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Volumn 27, Issue 8, 2013, Pages

Use of molecular biomarkers to inform adjuvant therapy for colon cancer

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; BEVACIZUMAB; BIOLOGICAL MARKER; CARCINOEMBRYONIC ANTIGEN; CETUXIMAB; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; K RAS PROTEIN; LEVAMISOLE; OXALIPLATIN; PROTEIN P53; SMAD2 PROTEIN; SMAD4 PROTEIN; THYMIDYLATE SYNTHASE;

EID: 84881292422     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (15)

References (57)
  • 1
    • 84865677954 scopus 로고    scopus 로고
    • Overcoming implementation challenges of personalized cancer therapy
    • Meric-Bernstam F, Mills GB. Overcoming implementation challenges of personalized cancer therapy. Nat Rev Clin Oncol. 2012;9:542-8.
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 542-548
    • Meric-Bernstam, F.1    Mills, G.B.2
  • 3
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Atkinson A, Colburn W, Degruttola V. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther. 2001;69:89-95.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 89-95
    • Atkinson, A.1    Colburn, W.2    Degruttola, V.3
  • 4
    • 67349111010 scopus 로고    scopus 로고
    • Predictive biomarkers in the development of oncology drugs: A therapeutic industry perspective
    • Fine BM, Amler L. Predictive biomarkers in the development of oncology drugs: a therapeutic industry perspective. Clin Pharmacol Ther. 2009;85:535-8.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 535-538
    • Fine, B.M.1    Amler, L.2
  • 5
    • 0025060806 scopus 로고
    • Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma
    • Moertel CG, Fleming TR, Macdonald JS, et al. Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. N Engl J Med. 1990;322:352-8.
    • (1990) N Engl J Med , vol.322 , pp. 352-358
    • Moertel, C.G.1    Fleming, T.R.2    Macdonald, J.S.3
  • 6
    • 4344587783 scopus 로고    scopus 로고
    • American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer
    • Benson AB, 3rd, Schrag D, Somerfield MR, et al. American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer. J Clin Oncol. 2004;22:3408-19.
    • (2004) J Clin Oncol , vol.22 , pp. 3408-3419
    • Benson, A.B.1    Schrag, D.2    Somerfield, M.R.3
  • 7
    • 84944371744 scopus 로고
    • Adjuvant therapy for patients with colon and rectal cancer
    • NIH Consensus Conference
    • NIH Consensus Conference. Adjuvant therapy for patients with colon and rectal cancer. JAMA. 1990;264:1444-50.
    • (1990) JAMA , vol.264 , pp. 1444-1450
  • 8
    • 36849064682 scopus 로고    scopus 로고
    • Adjuvant chemotherapy versus observation in patients with colorectal cancer: A randomised study
    • Gray R, Barnwell J, McConkey C, et al. Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study. Lancet. 2007;370:2020-9.
    • (2007) Lancet , vol.370 , pp. 2020-2029
    • Gray, R.1    Barnwell, J.2    McConkey, C.3
  • 9
    • 0032950293 scopus 로고    scopus 로고
    • International Multicentre Pooled Analysis of B2 Colon Cancer Trials (IMPACT B2) investigators
    • Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer
    • Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer. International Multicentre Pooled Analysis of B2 Colon Cancer Trials (IMPACT B2) investigators. J Clin Oncol. 1999;17:1356-63.
    • (1999) J Clin Oncol , vol.17 , pp. 1356-1363
  • 10
    • 2542563257 scopus 로고    scopus 로고
    • Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: Who benefits and by how much
    • Gill S, Loprinzi CL, Sargent DJ, et al. Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: who benefits and by how much? J Clin Oncol. 2004;22:1797-806.
    • (2004) J Clin Oncol , vol.22 , pp. 1797-1806
    • Gill, S.1    Loprinzi, C.L.2    Sargent, D.J.3
  • 11
    • 4344591790 scopus 로고    scopus 로고
    • Adjuvant therapy for stage II colon cancer: A systematic review from the Cancer Care Ontario Program in evidence-based care's gastrointestinal cancer disease site group
    • Figueredo A, Charette ML, Maroun J, et al. Adjuvant therapy for stage II colon cancer: a systematic review from the Cancer Care Ontario Program in evidence-based care's gastrointestinal cancer disease site group. J Clin Oncol. 2004;22:3395-407.
    • (2004) J Clin Oncol , vol.22 , pp. 3395-3407
    • Figueredo, A.1    Charette, M.L.2    Maroun, J.3
  • 12
    • 33847722573 scopus 로고    scopus 로고
    • Phase III trial of capecitabine plus oxaliplatin as adjuvant therapy for stage III colon cancer: A planned safety analysis in 1,864 patients
    • Schmoll HJ, Cartwright T, Tabernero J, et al. Phase III trial of capecitabine plus oxaliplatin as adjuvant therapy for stage III colon cancer: a planned safety analysis in 1,864 patients. J Clin Oncol. 2007;25:102-9.
    • (2007) J Clin Oncol , vol.25 , pp. 102-109
    • Schmoll, H.J.1    Cartwright, T.2    Tabernero, J.3
  • 13
    • 2542615200 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
    • Andre T, Boni C, Mounedji-Boudiaf L, et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med. 2004;350:2343-51.
    • (2004) N Engl J Med , vol.350 , pp. 2343-2351
    • Andre, T.1    Boni, C.2    Mounedji-Boudiaf, L.3
  • 14
    • 67650315187 scopus 로고    scopus 로고
    • Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial
    • Andre T, Boni C, Navarro M, et al. Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial. J Clin Oncol. 2009;27:3109-16.
    • (2009) J Clin Oncol , vol.27 , pp. 3109-3116
    • Andre, T.1    Boni, C.2    Navarro, M.3
  • 15
    • 34250210799 scopus 로고    scopus 로고
    • Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: Results from NSABP C-07
    • Kuebler JP, Wieand HS, O'Connell MJ, et al. Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: results from NSABP C-07. J Clin Oncol. 2007;25:2198-204.
    • (2007) J Clin Oncol , vol.25 , pp. 2198-2204
    • Kuebler, J.P.1    Wieand, H.S.2    O'Connell, M.J.3
  • 16
    • 34548160680 scopus 로고    scopus 로고
    • Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: Results of CALGB 89803
    • Saltz LB, Niedzwiecki D, Hollis D, et al. Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803. J Clin Oncol. 2007;25:3456-61.
    • (2007) J Clin Oncol , vol.25 , pp. 3456-3461
    • Saltz, L.B.1    Niedzwiecki, D.2    Hollis, D.3
  • 17
    • 67650290547 scopus 로고    scopus 로고
    • Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3
    • Van Cutsem E, Labianca R, Bodoky G, et al. Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3. J Clin Oncol. 2009;27:3117-25.
    • (2009) J Clin Oncol , vol.27 , pp. 3117-3125
    • van Cutsem, E.1    Labianca, R.2    Bodoky, G.3
  • 18
    • 63549145899 scopus 로고    scopus 로고
    • A phase III randomised trial of LV5FU2 + irinotecan versus LV5FU2 alone in adjuvant high-risk colon cancer (FNCLCC Accord02/FFCD9802)
    • Ychou M, Raoul JL, Douillard JY, et al. A phase III randomised trial of LV5FU2 + irinotecan versus LV5FU2 alone in adjuvant high-risk colon cancer (FNCLCC Accord02/FFCD9802). Ann Oncol. 2009;20:674-80.
    • (2009) Ann Oncol , vol.20 , pp. 674-680
    • Ychou, M.1    Raoul, J.L.2    Douillard, J.Y.3
  • 19
    • 79551521053 scopus 로고    scopus 로고
    • Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: Results of NSABP protocol C-08
    • Allegra CJ, Yothers G, O'Connell MJ, et al. Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08. J Clin Oncol. 2011;29:11-6.
    • (2011) J Clin Oncol , vol.29 , pp. 11-16
    • Allegra, C.J.1    Yothers, G.2    O'Connell, M.J.3
  • 20
    • 84870244259 scopus 로고    scopus 로고
    • Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): A phase 3 randomised controlled trial
    • de Gramont A, Van Cutsem E, Schmoll HJ, et al. Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial. Lancet Oncol. 2012;13:1225-33.
    • (2012) Lancet Oncol , vol.13 , pp. 1225-1233
    • de Gramont, A.1    van Cutsem, E.2    Schmoll, H.J.3
  • 21
    • 84859403854 scopus 로고    scopus 로고
    • Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: A randomized trial
    • Alberts SR, Sargent DJ, Nair S, et al. Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial. JAMA. 2012;307:1383-93.
    • (2012) JAMA , vol.307 , pp. 1383-1393
    • Alberts, S.R.1    Sargent, D.J.2    Nair, S.3
  • 22
    • 43049141451 scopus 로고    scopus 로고
    • Identification of patients with high-risk stage II colon cancer for adjuvant therapy
    • Quah HM, Chou JF, Gonen M, et al. Identification of patients with high-risk stage II colon cancer for adjuvant therapy. Dis Colon Rectum. 2008;51:503-7.
    • (2008) Dis Colon Rectum , vol.51 , pp. 503-507
    • Quah, H.M.1    Chou, J.F.2    Gonen, M.3
  • 23
    • 6944230093 scopus 로고    scopus 로고
    • Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging
    • O'Connell JB, Maggard MA, Ko CY. Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. J Natl Cancer Inst. 2004;96:1420-5.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1420-1425
    • O'Connell, J.B.1    Maggard, M.A.2    Ko, C.Y.3
  • 24
    • 0033866021 scopus 로고    scopus 로고
    • Updated protocol for the examination of specimens from patients with carcinomas of the colon and rectum, excluding carcinoid tumors, lymphomas, sarcomas, and tumors of the vermiform appendix: A basis for checklists. Cancer Committee
    • Compton CC. Updated protocol for the examination of specimens from patients with carcinomas of the colon and rectum, excluding carcinoid tumors, lymphomas, sarcomas, and tumors of the vermiform appendix: a basis for checklists. Cancer Committee. Arch Pathol Lab Med. 2000;124:1016-25.
    • (2000) Arch Pathol Lab Med , vol.124 , pp. 1016-10125
    • Compton, C.C.1
  • 25
    • 77954748953 scopus 로고    scopus 로고
    • Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer
    • Sargent DJ, Marsoni S, Monges G, et al. Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer. J Clin Oncol. 2010;28:3219-26.
    • (2010) J Clin Oncol , vol.28 , pp. 3219-3226
    • Sargent, D.J.1    Marsoni, S.2    Monges, G.3
  • 26
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
    • Ribic CM, Sargent DJ, Moore MJ, et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med. 2003;349:247-57.
    • (2003) N Engl J Med , vol.349 , pp. 247-257
    • Ribic, C.M.1    Sargent, D.J.2    Moore, M.J.3
  • 27
    • 0035912144 scopus 로고    scopus 로고
    • Molecular predictors of survival after adjuvant chemotherapy for colon cancer
    • Watanabe T, Wu TT, Catalano PJ, et al. Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med. 2001;344:1196-206.
    • (2001) N Engl J Med , vol.344 , pp. 1196-1206
    • Watanabe, T.1    Wu, T.T.2    Catalano, P.J.3
  • 28
    • 80051820416 scopus 로고    scopus 로고
    • Microsatellite instability and loss of heterozygosity at chromosomal location 18q: Prospective evaluation of biomarkers for stages II and III colon cancera study of CALGB 9851 and 89803
    • Bertagnolli MM, Redston M, Compton CC, et al. Microsatellite instability and loss of heterozygosity at chromosomal location 18q: prospective evaluation of biomarkers for stages II and III colon cancera study of CALGB 9851 and 89803. J Clin Oncol. 2011;29:3153-62.
    • (2011) J Clin Oncol , vol.29 , pp. 3153-3162
    • Bertagnolli, M.M.1    Redston, M.2    Compton, C.C.3
  • 30
    • 0034895979 scopus 로고    scopus 로고
    • P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma
    • Elsaleh H, Powell B, McCaul K, et al. P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma. Clin Cancer Res. 2001;7:1343-9.
    • (2001) Clin Cancer Res , vol.7 , pp. 1343-1349
    • Elsaleh, H.1    Powell, B.2    McCaul, K.3
  • 31
    • 24944525406 scopus 로고    scopus 로고
    • Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients
    • Westra JL, Schaapveld M, Hollema H, et al. Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients. J Clin Oncol. 2005;23:5635-43.
    • (2005) J Clin Oncol , vol.23 , pp. 5635-5643
    • Westra, J.L.1    Schaapveld, M.2    Hollema, H.3
  • 32
    • 77951967408 scopus 로고    scopus 로고
    • Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treated by 5-fluorouracil and leucovorin with or without oxaliplatin
    • Zaanan A, Cuilliere-Dartigues P, Guilloux A, et al. Impact of p53 expression and microsatellite instability on stage III colon cancer disease-free survival in patients treated by 5-fluorouracil and leucovorin with or without oxaliplatin. Ann Oncol. 2010;21:772-80.
    • (2010) Ann Oncol , vol.21 , pp. 772-780
    • Zaanan, A.1    Cuilliere-Dartigues, P.2    Guilloux, A.3
  • 33
    • 32544444419 scopus 로고    scopus 로고
    • The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: Influence of tumor site, type of mutation, and adjuvant treatment
    • Russo A, Bazan V, Iacopetta B, et al. The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment. J Clin Oncol. 2005;23:7518-28.
    • (2005) J Clin Oncol , vol.23 , pp. 7518-7528
    • Russo, A.1    Bazan, V.2    Iacopetta, B.3
  • 34
    • 78149327190 scopus 로고    scopus 로고
    • Clinical impact of microsatellite instability in colon cancer following adjuvant FOLFOX therapy
    • Kim ST, Lee J, Park SH, et al. Clinical impact of microsatellite instability in colon cancer following adjuvant FOLFOX therapy. Cancer Chemother Pharmacol. 2010;66:659-67.
    • (2010) Cancer Chemother Pharmacol , vol.66 , pp. 659-667
    • Kim, S.T.1    Lee, J.2    Park, S.H.3
  • 35
    • 0035444798 scopus 로고    scopus 로고
    • Kirsten ras mutations in patients with colorectal cancer: The 'RASCAL II' study
    • Andreyev HJ, Norman AR, Cunningham D, et al. Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study. Br J Cancer. 2001;85:692-6.
    • (2001) Br J Cancer , vol.85 , pp. 692-696
    • Andreyev, H.J.1    Norman, A.R.2    Cunningham, D.3
  • 36
    • 0032490124 scopus 로고    scopus 로고
    • Kirsten ras mutations in patients with colorectal cancer: The multicenter RASCAL study
    • Andreyev HJ, Norman AR, Cunningham D, et al. Kirsten ras mutations in patients with colorectal cancer: the multicenter RASCAL study. J Natl Cancer Inst. 1998;90:675-84.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 675-684
    • Andreyev, H.J.1    Norman, A.R.2    Cunningham, D.3
  • 37
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61:759-67.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 38
    • 0032033144 scopus 로고    scopus 로고
    • Ki-ras mutations and prognosis in colorectal cancer
    • Kressner U, Bjorheim J, Westring S, et al. Ki-ras mutations and prognosis in colorectal cancer. Eur J Cancer. 1998;34:518-21.
    • (1998) Eur J Cancer , vol.34 , pp. 518-521
    • Kressner, U.1    Bjorheim, J.2    Westring, S.3
  • 39
    • 73149107502 scopus 로고    scopus 로고
    • KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803
    • Ogino S, Meyerhardt JA, Irahara N, et al. KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803. Clin Cancer Res. 2009;15:7322-9.
    • (2009) Clin Cancer Res , vol.15 , pp. 7322-7329
    • Ogino, S.1    Meyerhardt, J.A.2    Irahara, N.3
  • 40
    • 75749102647 scopus 로고    scopus 로고
    • Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: Results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial
    • Roth AD, Tejpar S, Delorenzi M, et al. Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial. J Clin Oncol. 2010;28:466-74.
    • (2010) J Clin Oncol , vol.28 , pp. 466-474
    • Roth, A.D.1    Tejpar, S.2    Delorenzi, M.3
  • 43
    • 34249785078 scopus 로고    scopus 로고
    • Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis
    • Minoo P, Moyer MP, Jass JR. Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis. J Pathol. 2007;212:124-133.
    • (2007) J Pathol , vol.212 , pp. 124-133
    • Minoo, P.1    Moyer, M.P.2    Jass, J.R.3
  • 44
    • 1442290323 scopus 로고    scopus 로고
    • Thymidylate synthase expression and prognosis in colorectal cancer: A systematic review and meta-analysis
    • Popat S, Matakidou A, Houlston RS. Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis. J Clin Oncol. 2004;22:529-536.
    • (2004) J Clin Oncol , vol.22 , pp. 529-536
    • Popat, S.1    Matakidou, A.2    Houlston, R.S.3
  • 45
    • 3142773418 scopus 로고    scopus 로고
    • Oncogenic H-Ras up-regulates expression of ERCC1 to protect cells from platinum-based anticancer agents
    • Youn CK, Kim MH, Cho HJ, et al. Oncogenic H-Ras up-regulates expression of ERCC1 to protect cells from platinum-based anticancer agents. Cancer Res. 2004;64:4849-4857.
    • (2004) Cancer Res , vol.64 , pp. 4849-4857
    • Youn, C.K.1    Kim, M.H.2    Cho, H.J.3
  • 46
    • 0037213983 scopus 로고    scopus 로고
    • Cellular determinants of oxaliplatin sensitivity in colon cancer cell lines
    • Arnould S, Hennebelle I, Canal P, et al. Cellular determinants of oxaliplatin sensitivity in colon cancer cell lines. Eur J Cancer. 2003;39:112-119.
    • (2003) Eur J Cancer , vol.39 , pp. 112-119
    • Arnould, S.1    Hennebelle, I.2    Canal, P.3
  • 47
    • 0035576102 scopus 로고    scopus 로고
    • ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy
    • Shirota Y, Stoehlmacher J, Brabender J, et al. ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy. J Clin Oncol. 2001;4298-4304.
    • (2001) J Clin Oncol , pp. 4298-4304
    • Shirota, Y.1    Stoehlmacher, J.2    Brabender, J.3
  • 48
    • 60549103246 scopus 로고    scopus 로고
    • Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine
    • Uchida K, Danenberg PV, Danenberg KD, Grem JL. Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine. BMC Cancer. 2008;8:386.
    • (2008) BMC Cancer , vol.8 , pp. 386
    • Uchida, K.1    Danenberg, P.V.2    Danenberg, K.D.3    Grem, J.L.4
  • 49
    • 66349132712 scopus 로고    scopus 로고
    • ERCC-1 gene expression levels and outcome to FOLFOX chemotherapy in patients enrolled in CONFIRM1 and CONFIRM2
    • abstr 4131
    • Lenz HJ, Zhang W, Shi MM, et al. ERCC-1 gene expression levels and outcome to FOLFOX chemotherapy in patients enrolled in CONFIRM1 and CONFIRM2. J Clin Oncol. 2008;26(15S):abstr 4131.
    • (2008) J Clin Oncol , vol.26 , Issue.15
    • Lenz, H.J.1    Zhang, W.2    Shi, M.M.3
  • 50
    • 84866736621 scopus 로고    scopus 로고
    • TS and ERCC-1 mRNA expressions and clinical outcome in patients with metastatic colon cancer in CONFIRM-1 and -2 clinical trials
    • Grimminger PP, Shi M, Barrett C, et al. TS and ERCC-1 mRNA expressions and clinical outcome in patients with metastatic colon cancer in CONFIRM-1 and -2 clinical trials. Pharmacogenomics J. 2012.;12:404-411.
    • (2012) Pharmacogenomics J. , vol.12 , pp. 404-411
    • Grimminger, P.P.1    Shi, M.2    Barrett, C.3
  • 51
    • 60549093904 scopus 로고    scopus 로고
    • Prognostic value of ERCC1, thymidylate synthase, and glutathione S-trans-ferase pi for 5-FU/oxaliplatin chemotherapy in advanced colorectal cancer
    • Kim SH, Kwon HC, Oh SY, et al. Prognostic value of ERCC1, thymidylate synthase, and glutathione S-trans-ferase pi for 5-FU/oxaliplatin chemotherapy in advanced colorectal cancer. Am J Clin Oncol. 2009;32:38-43.
    • (2009) Am J Clin Oncol , vol.32 , pp. 38-43
    • Kim, S.H.1    Kwon, H.C.2    Oh, S.Y.3
  • 52
    • 45749127481 scopus 로고    scopus 로고
    • Predictive biomarkers of chemotherapy efficacy in colorectal cancer: Results from the UK MRC FOCUS trial
    • Braun MS, Richman SD, Quirke P, et al. Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial. J Clin Oncol. 2008;26:2690-2698.
    • (2008) J Clin Oncol , vol.26 , pp. 2690-2698
    • Braun, M.S.1    Richman, S.D.2    Quirke, P.3
  • 53
    • 84877619075 scopus 로고    scopus 로고
    • A colorectal cancer classification system that associates cellular phenotype and responses to therapy
    • Sadanandam A, Lyssiotis CA, Homicsko K, et al. A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nat Med. 2013;19:619-625.
    • (2013) Nat Med , vol.19 , pp. 619-625
    • Sadanandam, A.1    Lyssiotis, C.A.2    Homicsko, K.3
  • 54
    • 79951506562 scopus 로고    scopus 로고
    • Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer
    • Salazar R, Roepman P, Capella G, et al. Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer. J Clin Oncol. 2011;29:17-24.
    • (2011) J Clin Oncol , vol.29 , pp. 17-24
    • Salazar, R.1    Roepman, P.2    Capella, G.3
  • 55
    • 84879114673 scopus 로고    scopus 로고
    • Independent validation of a prognostic genomic signature (ColoPrint) for patients with stage II colon cancer
    • Maak M, Simon I, Nitsche U, et al. Independent validation of a prognostic genomic signature (ColoPrint) for patients with stage II colon cancer. Ann Surg. 2013;257:1053-1058.
    • (2013) Ann Surg , vol.257 , pp. 1053-1058
    • Maak, M.1    Simon, I.2    Nitsche, U.3
  • 56
    • 84879471309 scopus 로고    scopus 로고
    • Biologic determinants of tumor recurrence in stage II colon cancer: Validation study of the 12-gene recurrence score in Cancer and Leukemia Group B (CALGB) 9581
    • Venook AP, Niedzwiecki D, Lopatin M, et al. Biologic determinants of tumor recurrence in stage II colon cancer: validation study of the 12-gene recurrence score in Cancer and Leukemia Group B (CALGB) 9581. J Clin Oncol. 2013;31:1775-1781.
    • (2013) J Clin Oncol , vol.31 , pp. 1775-1781
    • Venook, A.P.1    Niedzwiecki, D.2    Lopatin, M.3
  • 57
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012;487:330-337.
    • (2012) Nature , vol.487 , pp. 330-337


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