Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine

BMC Cancer

Volumn 8, Issue , 2008, Pages

  Uchida, Kazumi ^a   Danenberg, Peter V ^a   Danenberg, Kathleen D ^b   Grem, Jean L ^c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Response Genetics Inc   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPECITABINE; DIHYDROPYRIMIDINE DEHYDROGENASE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; MESSENGER RNA; OXALIPLATIN; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE; ANTINEOPLASTIC AGENT; DEOXYCYTIDINE; DNA BINDING PROTEIN; DRUG DERIVATIVE; ENDONUCLEASE; ERCC1 PROTEIN, HUMAN; FLUOROURACIL; PLATINUM COMPLEX; TUMOR PROTEIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; COLORECTAL ADENOCARCINOMA; DRUG DOSE ESCALATION; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; FEMALE; GASTROINTESTINAL CARCINOMA; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; METASTASIS; MULTIPLE CYCLE TREATMENT; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PHASE 1 CLINICAL TRIAL; RECOMMENDED DRUG DOSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE ADENOCARCINOMA; TREATMENT RESPONSE; TUMOR BIOPSY; UNSPECIFIED SIDE EFFECT; COLORECTAL TUMOR; DRUG ADMINISTRATION; DRUG RESISTANCE; GENETICS; MIDDLE AGED; MORTALITY; SURVIVAL; TREATMENT FAILURE;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COLORECTAL NEOPLASMS; DEOXYCYTIDINE; DIHYDROURACIL DEHYDROGENASE (NADP); DNA-BINDING PROTEINS; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE, NEOPLASM; ENDONUCLEASES; FEMALE; FLUOROURACIL; GENE EXPRESSION; HUMANS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; ORGANOPLATINUM COMPOUNDS; RNA, MESSENGER; SURVIVAL ANALYSIS; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE; TREATMENT FAILURE;

EID: 60549103246     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-386     Document Type: Article

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