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Volumn 33, Issue 16, 2013, Pages 3330-3342

Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycleexit, is mediated by the protein phosphatase 2A/B55α holoenzyme

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; MYC PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN P107;

EID: 84881283766     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00082-13     Document Type: Article
Times cited : (26)

References (53)
  • 1
    • 36448963487 scopus 로고    scopus 로고
    • Structure-function analysis of the retinoblastoma tumor suppressor protein-is the whole a sum of its parts
    • Dick FA. 2007. Structure-function analysis of the retinoblastoma tumor suppressor protein-is the whole a sum of its parts. Cell Div. 2:26.
    • (2007) Cell Div. , vol.2 , pp. 26
    • Dick, F.A.1
  • 2
    • 0032437776 scopus 로고    scopus 로고
    • Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth
    • Graña X, Garriga J, Mayol X. 1998. Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth. Oncogene 17:3365-3383.
    • (1998) Oncogene , vol.17 , pp. 3365-3383
    • Graña, X.1    Garriga, J.2    Mayol, X.3
  • 3
    • 84859776765 scopus 로고    scopus 로고
    • Escape from cellular quiescence, p 3-22
    • In Enders GH (ed), Cell cycle deregulation in cancer. Springer Publishing, New York, NY
    • Sotillo E, Graña X. 2010. Escape from cellular quiescence, p 3-22. In Enders GH (ed), Cell cycle deregulation in cancer. Springer Publishing, New York, NY.
    • (2010)
    • Sotillo, E.1    Graña, X.2
  • 4
    • 84859774713 scopus 로고    scopus 로고
    • PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates
    • Kurimchak A, Graña X. 2012. PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates. Gene 499:1-7.
    • (2012) Gene , vol.499 , pp. 1-7
    • Kurimchak, A.1    Graña, X.2
  • 5
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1501-1512.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 6
    • 33751239778 scopus 로고    scopus 로고
    • Re-evaluating cell-cycle regulation by E2Fs
    • Rowland BD, Bernards R. 2006. Re-evaluating cell-cycle regulation by E2Fs. Cell 127:871-874.
    • (2006) Cell , vol.127 , pp. 871-874
    • Rowland, B.D.1    Bernards, R.2
  • 7
    • 84880475258 scopus 로고    scopus 로고
    • The CDK network: linking cycles of cell division and gene expression
    • Fisher RP. 2012. The CDK network: linking cycles of cell division and gene expression. Genes Cancer 3:731-738.
    • (2012) Genes Cancer , vol.3 , pp. 731-738
    • Fisher, R.P.1
  • 8
    • 84880497002 scopus 로고    scopus 로고
    • PP2A counterbalances phosphorylation of pRB and mitotic proteins by multiple CDKs: potential implications for PP2A disruption in cancer
    • Kurimchak A, Graña X. 2012. PP2A counterbalances phosphorylation of pRB and mitotic proteins by multiple CDKs: potential implications for PP2A disruption in cancer. Genes Cancer 3:739-748.
    • (2012) Genes Cancer , vol.3 , pp. 739-748
    • Kurimchak, A.1    Graña, X.2
  • 9
    • 84880485027 scopus 로고    scopus 로고
    • Mammalian interphase cdks: dispensable master regulators of the cell cycle
    • Enders GH. 2012. Mammalian interphase cdks: dispensable master regulators of the cell cycle. Genes Cancer 3:614-618.
    • (2012) Genes Cancer , vol.3 , pp. 614-618
    • Enders, G.H.1
  • 10
    • 84880486381 scopus 로고    scopus 로고
    • Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function
    • MacDonald J, Dick FA. 2012. Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function. Genes Cancer 3:619-633.
    • (2012) Genes Cancer , vol.3 , pp. 619-633
    • MacDonald, J.1    Dick, F.A.2
  • 11
    • 0037184608 scopus 로고    scopus 로고
    • G1 cyclin/CDK coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression
    • Calbó J, Parreño M, Sotillo E, Yong T, Mazo A, Garriga J, Graña X. 2002. G1 cyclin/CDK coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression. J. Biol. Chem. 277:50263-50274.
    • (2002) J. Biol. Chem. , vol.277 , pp. 50263-50274
    • Calbó, J.1    Parreño, M.2    Sotillo, E.3    Yong, T.4    Mazo, A.5    Garriga, J.6    Graña, X.7
  • 12
    • 46749090395 scopus 로고    scopus 로고
    • Downregulation of the phosphatase nuclear targeting subunit (PNUTS) triggers pRB dephosphorylation and apoptosis in pRB positive tumor cell lines
    • Graña X. 2008. Downregulation of the phosphatase nuclear targeting subunit (PNUTS) triggers pRB dephosphorylation and apoptosis in pRB positive tumor cell lines. Cancer Biol. Ther. 7:842-844.
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 842-844
    • Graña, X.1
  • 13
    • 84872786662 scopus 로고    scopus 로고
    • PP1 and PP2A phosphatases- cooperating partners in modulating retinoblastoma protein activation
    • Kolupaeva V, Janssens V. 2013. PP1 and PP2A phosphatases- cooperating partners in modulating retinoblastoma protein activation. FEBS J. 280:627-643.
    • (2013) FEBS J. , vol.280 , pp. 627-643
    • Kolupaeva, V.1    Janssens, V.2
  • 18
    • 61649127812 scopus 로고    scopus 로고
    • From promiscuity to precision: protein phosphatases get a makeover
    • Virshup DM, Shenolikar S. 2009. From promiscuity to precision: protein phosphatases get a makeover. Mol. Cell 33:537-545.
    • (2009) Mol. Cell , vol.33 , pp. 537-545
    • Virshup, D.M.1    Shenolikar, S.2
  • 20
    • 77956901785 scopus 로고    scopus 로고
    • B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation
    • Jayadeva G, Kurimchak A, Garriga J, Sotillo E, Davis AJ, Haines DS, Mumby M, Graña X. 2010. B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation. J. Biol. Chem. 285:29863-29873.
    • (2010) J. Biol. Chem. , vol.285 , pp. 29863-29873
    • Jayadeva, G.1    Kurimchak, A.2    Garriga, J.3    Sotillo, E.4    Davis, A.J.5    Haines, D.S.6    Mumby, M.7    Graña, X.8
  • 23
    • 0142149161 scopus 로고    scopus 로고
    • Protein phosphatase 2A associates with Rb2/p130 and mediates retinoic acid-induced growth suppression of ovarian carcinoma cells
    • Vuocolo SC, Purev E, Zhang D, Bartek J, Hansen K, Soprano DR, Soprano KJ. 2003. Protein phosphatase 2A associates with Rb2/p130 and mediates retinoic acid-induced growth suppression of ovarian carcinoma cells. J. Biol. Chem. 278:41881-41889.
    • (2003) J. Biol. Chem. , vol.278 , pp. 41881-41889
    • Vuocolo, S.C.1    Purev, E.2    Zhang, D.3    Bartek, J.4    Hansen, K.5    Soprano, D.R.6    Soprano, K.J.7
  • 24
    • 0038491622 scopus 로고    scopus 로고
    • A network of tran-scriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation
    • Dailey L, Laplantine E, Priore R, Basilico C. 2003. A network of tran-scriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation. J. Cell Biol. 161:1053-1066.
    • (2003) J. Cell Biol. , vol.161 , pp. 1053-1066
    • Dailey, L.1    Laplantine, E.2    Priore, R.3    Basilico, C.4
  • 25
    • 55349128561 scopus 로고    scopus 로고
    • PP2A-mediated dephosphorylation of p107 plays a critical role in chondrocyte cell cycle arrest by FGF
    • doi:10.1371/journal.pone.0003447
    • Kolupaeva V, Laplantine E, Basilico C. 2008. PP2A-mediated dephosphorylation of p107 plays a critical role in chondrocyte cell cycle arrest by FGF. PLoS One 3:e3447. doi:10.1371/journal.pone.0003447.
    • (2008) PLoS One , vol.3
    • Kolupaeva, V.1    Laplantine, E.2    Basilico, C.3
  • 27
    • 0037097976 scopus 로고    scopus 로고
    • FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease
    • Ornitz DM, Marie PJ. 2002. FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes Dev. 16:1446-1465.
    • (2002) Genes Dev. , vol.16 , pp. 1446-1465
    • Ornitz, D.M.1    Marie, P.J.2
  • 28
    • 79960124728 scopus 로고    scopus 로고
    • Nuclear factor-B (NF-B) p65 interacts with Stat5b in growth plate chondrocytes and mediates the effects of growth hormone on chondrogenesis and on the expression of insulin-like growth factor-1 and bone morphogenetic protein-2
    • Wu S, Morrison A, Sun H, De Luca F. 2011. Nuclear factor-B (NF-B) p65 interacts with Stat5b in growth plate chondrocytes and mediates the effects of growth hormone on chondrogenesis and on the expression of insulin-like growth factor-1 and bone morphogenetic protein-2. J. Biol. Chem. 286:24726-24734.
    • (2011) J. Biol. Chem. , vol.286 , pp. 24726-24734
    • Wu, S.1    Morrison, A.2    Sun, H.3    De Luca, F.4
  • 30
    • 76349090199 scopus 로고    scopus 로고
    • CDK8 is a positive regulator of transcriptional elongation within the serum response network
    • Donner AJ, Ebmeier CC, Taatjes DJ, Espinosa JM. 2010. CDK8 is a positive regulator of transcriptional elongation within the serum response network. Nat. Struct. Mol. Biol. 17:194-201.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 194-201
    • Donner, A.J.1    Ebmeier, C.C.2    Taatjes, D.J.3    Espinosa, J.M.4
  • 31
    • 84858981981 scopus 로고    scopus 로고
    • Complex effects of flavopiridol on the expression of primary response genes
    • Keskin H, Garriga J, Georlette D, Graña X. 2012. Complex effects of flavopiridol on the expression of primary response genes. Cell Div. 7:11.
    • (2012) Cell Div. , vol.7 , pp. 11
    • Keskin, H.1    Garriga, J.2    Georlette, D.3    Graña, X.4
  • 33
    • 0033151612 scopus 로고    scopus 로고
    • FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway
    • Sahni M, Ambrosetti DC, Mansukhani A, Gertner R, Levy D, Basilico C. 1999. FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway. Genes Dev. 13:1361- 1366.
    • (1999) Genes Dev. , vol.13
    • Sahni, M.1    Ambrosetti, D.C.2    Mansukhani, A.3    Gertner, R.4    Levy, D.5    Basilico, C.6
  • 34
    • 0035800801 scopus 로고    scopus 로고
    • Fibroblast growth factor inhibits chondrocytic growth through induction of p21 and subsequent inactivation of cyclin E-Cdk2
    • Aikawa T, Segre GV, Lee K. 2001. Fibroblast growth factor inhibits chondrocytic growth through induction of p21 and subsequent inactivation of cyclin E-Cdk2. J. Biol. Chem. 276:29347-29352.
    • (2001) J. Biol. Chem. , vol.276 , pp. 29347-29352
    • Aikawa, T.1    Segre, G.V.2    Lee, K.3
  • 36
    • 78349282593 scopus 로고    scopus 로고
    • FGF inhibits the activity of the cyclin B1/CDK1 kinase to induce a transient G(2) arrest in RCS chondrocytes
    • Tran T, Kolupaeva V, Basilico C. 2010. FGF inhibits the activity of the cyclin B1/CDK1 kinase to induce a transient G(2) arrest in RCS chondrocytes. Cell Cycle 9:4379-4386.
    • (2010) Cell Cycle , vol.9 , pp. 4379-4386
    • Tran, T.1    Kolupaeva, V.2    Basilico, C.3
  • 39
    • 0029811716 scopus 로고    scopus 로고
    • G1 cyclin/Cdk-independent phosphorylation and accumulation of p130 during the transition from G1 to G0 lead to its association with E2F-4
    • Mayol X, Garriga J, Graña X. 1996. G1 cyclin/Cdk-independent phosphorylation and accumulation of p130 during the transition from G1 to G0 lead to its association with E2F-4. Oncogene 13:237-246.
    • (1996) Oncogene , vol.13 , pp. 237-246
    • Mayol, X.1    Garriga, J.2    Graña, X.3
  • 40
    • 84880476319 scopus 로고    scopus 로고
    • Deciphering the new role of the Greatwall/PP2A pathway in cell cycle control
    • Lorca T, Castro A. 2012. Deciphering the new role of the Greatwall/PP2A pathway in cell cycle control. Genes Cancer 3:712-720.
    • (2012) Genes Cancer , vol.3 , pp. 712-720
    • Lorca, T.1    Castro, A.2
  • 41
    • 0037135987 scopus 로고    scopus 로고
    • FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest
    • Laplantine E, Rossi F, Sahni M, Basilico C, Cobrinik D. 2002. FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest. J. Cell Biol. 158:741-750.
    • (2002) J. Cell Biol. , vol.158 , pp. 741-750
    • Laplantine, E.1    Rossi, F.2    Sahni, M.3    Basilico, C.4    Cobrinik, D.5
  • 42
    • 0030955563 scopus 로고    scopus 로고
    • Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development
    • Yan Y, Frisen J, Lee MH, Massague J, Barbacid M. 1997. Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev. 11:973-983.
    • (1997) Genes Dev. , vol.11 , pp. 973-983
    • Yan, Y.1    Frisen, J.2    Lee, M.H.3    Massague, J.4    Barbacid, M.5
  • 44
    • 84873412441 scopus 로고    scopus 로고
    • The Greatwall kinase: a new pathway in the control of the cell cycle
    • Lorca T, Castro A. 2013. The Greatwall kinase: a new pathway in the control of the cell cycle. Oncogene 32:537-543.
    • (2013) Oncogene , vol.32 , pp. 537-543
    • Lorca, T.1    Castro, A.2
  • 45
    • 73949151141 scopus 로고    scopus 로고
    • The Mphase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites
    • Castilho PV, Williams BC, Mochida S, Zhao Y, Goldberg ML. 2009. The Mphase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites. Mol. Biol. Cell 20: 4777-4789.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 4777-4789
    • Castilho, P.V.1    Williams, B.C.2    Mochida, S.3    Zhao, Y.4    Goldberg, M.L.5
  • 46
    • 70349210060 scopus 로고    scopus 로고
    • Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts
    • Mochida S, Ikeo S, Gannon J, Hunt T. 2009. Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts. EMBO J. 28:2777-2785.
    • (2009) EMBO J. , vol.28 , pp. 2777-2785
    • Mochida, S.1    Ikeo, S.2    Gannon, J.3    Hunt, T.4
  • 49
    • 78650366525 scopus 로고    scopus 로고
    • Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis
    • Mochida S, Maslen SL, Skehel M, Hunt T. 2010. Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis. Science 330:1670-1673.
    • (2010) Science , vol.330 , pp. 1670-1673
    • Mochida, S.1    Maslen, S.L.2    Skehel, M.3    Hunt, T.4
  • 52
    • 0038708117 scopus 로고    scopus 로고
    • SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells
    • Bhattacharya S, Garriga J, Calbo J, Yong T, Haines DS, Graña X. 2003. SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells. Oncogene 22:2443-2451.
    • (2003) Oncogene , vol.22 , pp. 2443-2451
    • Bhattacharya, S.1    Garriga, J.2    Calbo, J.3    Yong, T.4    Haines, D.S.5    Graña, X.6
  • 53
    • 0037112174 scopus 로고    scopus 로고
    • The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the proteinubiquitin ligase SCF(Skp2)
    • Tedesco D, Lukas J, Reed SI. 2002. The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the proteinubiquitin ligase SCF(Skp2). Genes Dev. 16:2946-2957.
    • (2002) Genes Dev. , vol.16 , pp. 2946-2957
    • Tedesco, D.1    Lukas, J.2    Reed, S.I.3


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