-
1
-
-
0027458292
-
Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases
-
Alberts, A. S., A. M. Thorburn, S. Shenolikar, M. C. Mumby, and J. R. Feramisco. 1993. Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases. Proc. Natl. Acad. Sci. USA 90:388-392.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 388-392
-
-
Alberts, A.S.1
Thorburn, A.M.2
Shenolikar, S.3
Mumby, M.C.4
Feramisco, J.R.5
-
2
-
-
27944448894
-
Involvement of PP2A in viral and cellular transformation
-
Arroyo, J. D., and W. C. Hahn. 2005. Involvement of PP2A in viral and cellular transformation. Oncogene 24:7746-7755.
-
(2005)
Oncogene
, vol.24
, pp. 7746-7755
-
-
Arroyo, J.D.1
Hahn, W.C.2
-
3
-
-
0141861977
-
Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage
-
Avni, D., H. Yang, F. Martelli, F. Hofmann, W. M. ElShamy, S. Ganesan, R. Scully, and D. M. Livingston. 2003. Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage. Mol. Cell 12:735-746.
-
(2003)
Mol. Cell
, vol.12
, pp. 735-746
-
-
Avni, D.1
Yang, H.2
Martelli, F.3
Hofmann, F.4
ElShamy, W.M.5
Ganesan, S.6
Scully, R.7
Livingston, D.M.8
-
4
-
-
15544367398
-
Unlocking the secrets of cell signaling
-
Berridge, M. J. 2005. Unlocking the secrets of cell signaling. Annu. Rev. Physiol. 67:1-21.
-
(2005)
Annu. Rev. Physiol
, vol.67
, pp. 1-21
-
-
Berridge, M.J.1
-
5
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
Campisi, J. 2005. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120:513-522.
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
6
-
-
0038482115
-
Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130
-
Cicchillitti, L., P. Fasanaro, P. Biglioli, M. C. Capogrossi, and F. Martelli. 2003. Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130. J. Biol. Chem. 278:19509-19517.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 19509-19517
-
-
Cicchillitti, L.1
Fasanaro, P.2
Biglioli, P.3
Capogrossi, M.C.4
Martelli, F.5
-
7
-
-
18344383345
-
Pocket proteins and cell cycle control
-
Cobrinik, D. 2005. Pocket proteins and cell cycle control. Oncogene 24:2796-2809.
-
(2005)
Oncogene
, vol.24
, pp. 2796-2809
-
-
Cobrinik, D.1
-
8
-
-
0024792262
-
Protein phosphatases come of age
-
Cohen, P., and P. T. Cohen. 1989. Protein phosphatases come of age. J. Biol. Chem. 264:21435-21438.
-
(1989)
J. Biol. Chem
, vol.264
, pp. 21435-21438
-
-
Cohen, P.1
Cohen, P.T.2
-
9
-
-
0037022387
-
Analysis of Cdc6 function in the assembly of mammalian prereplication complexes
-
Cook, J. G., C. H. Park, T. W. Burke, G. Leone, J. DeGregori, A. Engel, and J. R. Nevins. 2002. Analysis of Cdc6 function in the assembly of mammalian prereplication complexes. Proc. Natl. Acad. Sci. USA 99:1347-1352.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1347-1352
-
-
Cook, J.G.1
Park, C.H.2
Burke, T.W.3
Leone, G.4
DeGregori, J.5
Engel, A.6
Nevins, J.R.7
-
10
-
-
33745987280
-
Cyclin D1 degradation enhances endothelial cell survival upon oxidative stress
-
Fasanaro, P., A. Magenta, G. Zaccagnini, L. Cicchillitti, S. Fucile, F. Eusebi, P. Biglioli, M. C. Capogrossi, and F. Martelli. 2006. Cyclin D1 degradation enhances endothelial cell survival upon oxidative stress. FASEB J. 20:1242-1244.
-
(2006)
FASEB J
, vol.20
, pp. 1242-1244
-
-
Fasanaro, P.1
Magenta, A.2
Zaccagnini, G.3
Cicchillitti, L.4
Fucile, S.5
Eusebi, F.6
Biglioli, P.7
Capogrossi, M.C.8
Martelli, F.9
-
11
-
-
33748039092
-
Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins
-
Felsani, A., A. M. Mileo, and M. G. Paggi. 2006. Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins. Oncogene 25:5277-5285.
-
(2006)
Oncogene
, vol.25
, pp. 5277-5285
-
-
Felsani, A.1
Mileo, A.M.2
Paggi, M.G.3
-
12
-
-
28844473846
-
Opinion: Radical medicine: treating ageing to cure disease
-
Finkel, T. 2005. Opinion: Radical medicine: treating ageing to cure disease. Nat. Rev. Mol. Cell Biol. 6:971-976.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 971-976
-
-
Finkel, T.1
-
13
-
-
0035988776
-
HIV-based vectors. Preparation and use
-
Follenzi, A., and L. Naldini. 2002. HIV-based vectors. Preparation and use. Methods Mol. Med. 69:259-274.
-
(2002)
Methods Mol. Med
, vol.69
, pp. 259-274
-
-
Follenzi, A.1
Naldini, L.2
-
14
-
-
13944277105
-
A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130
-
Garriga, J., A. L. Jayaraman, A. Limon, G. Jayadeva, E. Sotillo, M. Truongcao, A. Patsialou, B. E. Wadzinski, and X. Grana. 2004. A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130. Cell Cycle 3:1320-1330.
-
(2004)
Cell Cycle
, vol.3
, pp. 1320-1330
-
-
Garriga, J.1
Jayaraman, A.L.2
Limon, A.3
Jayadeva, G.4
Sotillo, E.5
Truongcao, M.6
Patsialou, A.7
Wadzinski, B.E.8
Grana, X.9
-
15
-
-
0036594890
-
The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
-
Gartel, A. L., and A. L. Tyner. 2002. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol. Cancer Ther. 1:639-649.
-
(2002)
Mol. Cancer Ther
, vol.1
, pp. 639-649
-
-
Gartel, A.L.1
Tyner, A.L.2
-
16
-
-
33748047128
-
RB and cell cycle progression
-
Giacinti, C., and A. Giordano. 2006. RB and cell cycle progression. Oncogene 25:5220-5227.
-
(2006)
Oncogene
, vol.25
, pp. 5220-5227
-
-
Giacinti, C.1
Giordano, A.2
-
17
-
-
33646761687
-
Structural basis for diversity of the EF-hand calcium-binding proteins
-
Grabarek, Z. 2006. Structural basis for diversity of the EF-hand calcium-binding proteins. J. Mol. Biol. 359:509-525.
-
(2006)
J. Mol. Biol
, vol.359
, pp. 509-525
-
-
Grabarek, Z.1
-
18
-
-
0029820095
-
The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
-
Hofmann, F., F. Martelli, D. M. Livingston, and Z. Wang. 1996. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev. 10:2949-2959.
-
(1996)
Genes Dev
, vol.10
, pp. 2949-2959
-
-
Hofmann, F.1
Martelli, F.2
Livingston, D.M.3
Wang, Z.4
-
19
-
-
0032570321
-
Hydrogen peroxide induces intracellular calcium oscillations in human aortic endothelial cells
-
Hu, Q., S. Corda, J. L. Zweier, M. C. Capogrossi, and R. C. Ziegelstein. 1998. Hydrogen peroxide induces intracellular calcium oscillations in human aortic endothelial cells. Circulation 97:268-275.
-
(1998)
Circulation
, vol.97
, pp. 268-275
-
-
Hu, Q.1
Corda, S.2
Zweier, J.L.3
Capogrossi, M.C.4
Ziegelstein, R.C.5
-
20
-
-
0035252894
-
Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
-
Janssens, V., and J. Goris. 2001. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem. J. 353:417-439.
-
(2001)
Biochem. J
, vol.353
, pp. 417-439
-
-
Janssens, V.1
Goris, J.2
-
22
-
-
0038532312
-
Identification and functional analysis of two Ca2+-binding EF-hand motifs in the B″/PR72 subunit of protein phosphatase 2A
-
Janssens, V., J. Jordens, I. Stevens, C. Van Hoof, E. Martens, H. De Smedt, Y. Engelborghs, E. Waelkens, and J. Goris. 2003. Identification and functional analysis of two Ca2+-binding EF-hand motifs in the B″/PR72 subunit of protein phosphatase 2A. J. Biol. Chem. 278:10697-10706.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 10697-10706
-
-
Janssens, V.1
Jordens, J.2
Stevens, I.3
Van Hoof, C.4
Martens, E.5
De Smedt, H.6
Engelborghs, Y.7
Waelkens, E.8
Goris, J.9
-
23
-
-
34447283580
-
CIP2A inhibits PP2A in human malignancies
-
Junttila, M. R., P. Puustinen, M. Niemela, R. Ahola, H. Arnold, T. Bottzauw, R. Ala-aho, C. Nielsen, J. Ivaska, Y. Taya, S. L. Lu, S. Lin, E. K. Chan, X. J. Wang, R. Grenman, J. Kast, T. Kallunki, R. Sears, V. M. Kahari, and J. Westermarck. 2007. CIP2A inhibits PP2A in human malignancies. Cell 130:51-62.
-
(2007)
Cell
, vol.130
, pp. 51-62
-
-
Junttila, M.R.1
Puustinen, P.2
Niemela, M.3
Ahola, R.4
Arnold, H.5
Bottzauw, T.6
Ala-aho, R.7
Nielsen, C.8
Ivaska, J.9
Taya, Y.10
Lu, S.L.11
Lin, S.12
Chan, E.K.13
Wang, X.J.14
Grenman, R.15
Kast, J.16
Kallunki, T.17
Sears, R.18
Kahari, V.M.19
Westermarck, J.20
more..
-
24
-
-
0034669029
-
Nuclear organization of DNA replication in primary mammalian cells
-
Kennedy, B. K., D. A. Barbie, M. Classon, N. Dyson, and E. Harlow. 2000. Nuclear organization of DNA replication in primary mammalian cells. Genes Dev. 14:2855-2868.
-
(2000)
Genes Dev
, vol.14
, pp. 2855-2868
-
-
Kennedy, B.K.1
Barbie, D.A.2
Classon, M.3
Dyson, N.4
Harlow, E.5
-
25
-
-
0033796320
-
RB-dependent S-phase response to DNA damage
-
Knudsen, K. E., D. Booth, S. Naderi, Z. Sever-Chroneos, A. F. Fribourg, I. C. Hunton, J. R. Feramisco, J. Y. Wang, and E. S. Knudsen. 2000. RB-dependent S-phase response to DNA damage. Mol. Cell. Biol. 20:7751-7763.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 7751-7763
-
-
Knudsen, K.E.1
Booth, D.2
Naderi, S.3
Sever-Chroneos, Z.4
Fribourg, A.F.5
Hunton, I.C.6
Feramisco, J.R.7
Wang, J.Y.8
Knudsen, E.S.9
-
26
-
-
0036161826
-
Two conserved domains in regulatory B subunits mediate binding to the A subunit of protein phosphatase 2A
-
Li, X., and D. M. Virshup. 2002. Two conserved domains in regulatory B subunits mediate binding to the A subunit of protein phosphatase 2A. Eur. J. Biochem. 269:546-552.
-
(2002)
Eur. J. Biochem
, vol.269
, pp. 546-552
-
-
Li, X.1
Virshup, D.M.2
-
27
-
-
0344443762
-
SV40 large T antigen promotes dephosphorylation of p130
-
Lin, J. Y., and J. A. DeCaprio. 2003. SV40 large T antigen promotes dephosphorylation of p130. J. Biol. Chem. 278:46482-46487.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 46482-46487
-
-
Lin, J.Y.1
DeCaprio, J.A.2
-
28
-
-
1242276313
-
Alteration in temporal kinetics of Ca2+ signaling and control of growth and proliferation
-
Lipskaia, L., and A. M. Lompre. 2004. Alteration in temporal kinetics of Ca2+ signaling and control of growth and proliferation. Biol. Cell 96:55-68.
-
(2004)
Biol. Cell
, vol.96
, pp. 55-68
-
-
Lipskaia, L.1
Lompre, A.M.2
-
29
-
-
0035836772
-
p19ARF targets certain E2F species for degradation
-
Martelli, F., T. Hamilton, D. P. Silver, N. E. Sharpless, N. Bardeesy, M. Rokas, R. A. DePinho, D. M. Livingston, and S. R. Grossman. 2001. p19ARF targets certain E2F species for degradation. Proc. Natl. Acad. Sci. USA 98:4455-4460.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4455-4460
-
-
Martelli, F.1
Hamilton, T.2
Silver, D.P.3
Sharpless, N.E.4
Bardeesy, N.5
Rokas, M.6
DePinho, R.A.7
Livingston, D.M.8
Grossman, S.R.9
-
30
-
-
14844342479
-
The retinoblastoma protein - from bench to bedside
-
Mittnacht, S. 2005. The retinoblastoma protein - from bench to bedside. Eur. J. Cell Biol. 84:97-107.
-
(2005)
Eur. J. Cell Biol
, vol.84
, pp. 97-107
-
-
Mittnacht, S.1
-
31
-
-
27644569730
-
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein
-
Neviani, P., R. Santhanam, R. Trotta, M. Notari, B. W. Blaser, S. Liu, H. Mao, J. S. Chang, A. Galietta, A. Uttam, D. C. Roy, M. Valtieri, R. Bruner-Klisovic, M. A. Caligiuri, C. D. Bloomfield, G. Marcucci, and D. Perrotti. 2005. The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein. Cancer Cell 8:355-368.
-
(2005)
Cancer Cell
, vol.8
, pp. 355-368
-
-
Neviani, P.1
Santhanam, R.2
Trotta, R.3
Notari, M.4
Blaser, B.W.5
Liu, S.6
Mao, H.7
Chang, J.S.8
Galietta, A.9
Uttam, A.10
Roy, D.C.11
Valtieri, M.12
Bruner-Klisovic, R.13
Caligiuri, M.A.14
Bloomfield, C.D.15
Marcucci, G.16
Perrotti, D.17
-
32
-
-
0025103372
-
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A
-
Pallas, D. C., L. K. Shahrik, B. L. Martin, S. Jaspers, T. B. Miller, D. L. Brautigan, and T. M. Roberts. 1990. Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell 60:167-176.
-
(1990)
Cell
, vol.60
, pp. 167-176
-
-
Pallas, D.C.1
Shahrik, L.K.2
Martin, B.L.3
Jaspers, S.4
Miller, T.B.5
Brautigan, D.L.6
Roberts, T.M.7
-
33
-
-
33745797761
-
Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells
-
Peers, C., P. Kang, J. P. Boyle, K. E. Porter, H. A. Pearson, I. F. Smith, and P. J. Kemp. 2006. Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells. Novartis Found. Symp. 272:119-140.
-
(2006)
Novartis Found. Symp
, vol.272
, pp. 119-140
-
-
Peers, C.1
Kang, P.2
Boyle, J.P.3
Porter, K.E.4
Pearson, H.A.5
Smith, I.F.6
Kemp, P.J.7
-
34
-
-
18344369616
-
Biochemical and cellular mechanisms of mammalian CDK inhibitors: A few unresolved issues
-
Pei, X. H., and Y. Xiong. 2005. Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues. Oncogene 24:2787-2795.
-
(2005)
Oncogene
, vol.24
, pp. 2787-2795
-
-
Pei, X.H.1
Xiong, Y.2
-
35
-
-
0028983370
-
-
Qin, X.-Q., D. M. Livingston, M. Ewen, W. R. Sellers, Z. Arany, and W. G. Kaelin, Jr. 1995. The transcription factor E2F-1 is a downstream target of RB action. Mol. Cell. Biol. 15:742-755.
-
Qin, X.-Q., D. M. Livingston, M. Ewen, W. R. Sellers, Z. Arany, and W. G. Kaelin, Jr. 1995. The transcription factor E2F-1 is a downstream target of RB action. Mol. Cell. Biol. 15:742-755.
-
-
-
-
36
-
-
0035100119
-
The role of the SV40 ST antigen in cell growth promotion and transformation
-
Rundell, K., and R. Parakati. 2001. The role of the SV40 ST antigen in cell growth promotion and transformation. Semin. Cancer Biol. 11:5-13.
-
(2001)
Semin. Cancer Biol
, vol.11
, pp. 5-13
-
-
Rundell, K.1
Parakati, R.2
-
37
-
-
0025162212
-
C-terminal truncation of the retinoblastoma gene product leads to functional inactivation
-
Shew, J. Y., B. T. Lin, P. L. Chen, B. Y. Tseng, T. L. Yang-Feng, and W. H. Lee. 1990. C-terminal truncation of the retinoblastoma gene product leads to functional inactivation. Proc. Natl. Acad. Sci. USA 87:6-10.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6-10
-
-
Shew, J.Y.1
Lin, B.T.2
Chen, P.L.3
Tseng, B.Y.4
Yang-Feng, T.L.5
Lee, W.H.6
-
38
-
-
0037244417
-
Identification and characterization of B″-subunits of protein phosphatase 2 A in Xenopus laevis oocytes and adult tissues
-
Stevens, I., V. Janssens, E. Martens, S. Dilworth, J. Goris, and C. Van Hoof. 2003. Identification and characterization of B″-subunits of protein phosphatase 2 A in Xenopus laevis oocytes and adult tissues. Eur. J. Biochem. 270:376-387.
-
(2003)
Eur. J. Biochem
, vol.270
, pp. 376-387
-
-
Stevens, I.1
Janssens, V.2
Martens, E.3
Dilworth, S.4
Goris, J.5
Van Hoof, C.6
-
39
-
-
29444461333
-
High glucose-induced apoptosis through store-operated calcium entry and calcineurin in human umbilical vein endothelial cells
-
Tamareille, S., O. Mignen, T. Capiod, C. Rucker-Martin, and D. Feuvray. 2006. High glucose-induced apoptosis through store-operated calcium entry and calcineurin in human umbilical vein endothelial cells. Cell Calcium 39:47-55.
-
(2006)
Cell Calcium
, vol.39
, pp. 47-55
-
-
Tamareille, S.1
Mignen, O.2
Capiod, T.3
Rucker-Martin, C.4
Feuvray, D.5
-
40
-
-
0033630808
-
Role of pRB dephosphorylation in cell cycle regulation
-
Tamrakar, S., E. Rubin, and J. W. Ludlow. 2000. Role of pRB dephosphorylation in cell cycle regulation. Front. Biosci. 5:D121-D137.
-
(2000)
Front. Biosci
, vol.5
-
-
Tamrakar, S.1
Rubin, E.2
Ludlow, J.W.3
-
41
-
-
1442285922
-
PP2A fulfills its promises as tumor suppressor: Which subunits are important?
-
Van Hoof, C., and J. Goris. 2004. PP2A fulfills its promises as tumor suppressor: which subunits are important? Cancer Cell 5:105-106.
-
(2004)
Cancer Cell
, vol.5
, pp. 105-106
-
-
Van Hoof, C.1
Goris, J.2
-
42
-
-
0033552957
-
Functional interaction between a novel protein phosphatase 2A regulatory subunit, PR59, and the retinoblastoma-related p107 protein
-
Voorhoeve, P. M., E. M. Hijmans, and R. Bernards. 1999. Functional interaction between a novel protein phosphatase 2A regulatory subunit, PR59, and the retinoblastoma-related p107 protein. Oncogene 18:515-524.
-
(1999)
Oncogene
, vol.18
, pp. 515-524
-
-
Voorhoeve, P.M.1
Hijmans, E.M.2
Bernards, R.3
-
43
-
-
0142149161
-
Protein phosphatase 2A associates with Rb2/p130 and mediates retinoic acid-induced growth suppression of ovarian carcinoma cells
-
Vuocolo, S., E. Purev, D. Zhang, J. Bartek, K. Hansen, D. R. Soprano, and K. J. Soprano. 2003. Protein phosphatase 2A associates with Rb2/p130 and mediates retinoic acid-induced growth suppression of ovarian carcinoma cells. J. Biol. Chem. 278:41881-41889.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 41881-41889
-
-
Vuocolo, S.1
Purev, E.2
Zhang, D.3
Bartek, J.4
Hansen, K.5
Soprano, D.R.6
Soprano, K.J.7
-
44
-
-
0033972224
-
PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells
-
Yan, Z., S. A. Fedorov, M. C. Mumby, and R. S. Williams. 2000. PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells. Mol. Cell. Biol. 20:1021-1029.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 1021-1029
-
-
Yan, Z.1
Fedorov, S.A.2
Mumby, M.C.3
Williams, R.S.4
-
45
-
-
0037437370
-
Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: Differences in expression, subunit interaction, and evolution
-
Zhou, J., H. T. Pham, R. Ruediger, and G. Walter. 2003. Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolution. Biochem. J. 369:387-398.
-
(2003)
Biochem. J
, vol.369
, pp. 387-398
-
-
Zhou, J.1
Pham, H.T.2
Ruediger, R.3
Walter, G.4
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