Downregulation of the phosphatase nuclear targeting subunit (PNUTS) triggers pRB dephosphorylation and apoptosis in pRB positive tumor cell lines

Cancer Biology and Therapy

Volumn 7, Issue 6, 2008, Pages 842-844

  Graña, Xavier ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CDK; Cell cycle; Cyclin; E2F 1; p107; p130; Pocket protein; PP1; PP2A

Indexed keywords

CASPASE 8; CYCLIN DEPENDENT KINASE 2; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTIEN PNUTS; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1; BCAR1 PROTEIN, HUMAN; CRK ASSOCIATED SUBSTRATE PROTEIN; CYCLIN DEPENDENT KINASE; DNA BINDING PROTEIN; NUCLEAR PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2; PPP1R10 PROTEIN, HUMAN; RNA BINDING PROTEIN;

APOPTOSIS; CELL CYCLE PROGRESSION; CELL DIVISION; CELL PROLIFERATION; DOWN REGULATION; HUMAN; NOTE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR CELL LINE; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL CYCLE; PHOSPHORYLATION; PHYSIOLOGY;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CRK-ASSOCIATED SUBSTRATE PROTEIN; CYCLIN-DEPENDENT KINASES; DNA-BINDING PROTEINS; E2F1 TRANSCRIPTION FACTOR; HUMANS; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; RETINOBLASTOMA PROTEIN; RNA-BINDING PROTEINS;

EID: 46749090395     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.7.6.6298     Document Type: Note

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