Solution NMR analyses of the C-type carbohydrate recognition domain of DC-SIGNR protein reveal different binding modes for HIV-derived oligosaccharides and smaller glycan fragments

Journal of Biological Chemistry

Volumn 288, Issue 31, 2013, Pages 22745-22757

  Probert, Fay ^a   Whittaker, Sara B M ^d   Crispin, Max ^e   Mitchell, Daniel A ^b   Dixon, Ann M ^c  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

^c UNIVERSITY OF WARWICK   (United Kingdom)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING MODES; C-TYPE LECTINS; CARBOHYDRATE-RECOGNITION DOMAINS; DRUG TARGETS; GLYCANS; LIGAND BINDING; SOLUTION DYNAMICS; SOLUTION NMR;

BINDING ENERGY; PROTEINS;

POLYSACCHARIDES;

DENDRITIC CELL SPECIFIC ICAM 3 GABBING NON INTEGRIN RELATED PROTEIN; DNA FRAGMENT; GLYCAN; MEMBRANE PROTEIN; NITROGEN 15; OLIGOSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONFORMATION; CONTROLLED STUDY; CRYSTALLOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS; LIGAND BINDING; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

C-TYPE LECTIN; CALCIUM-BINDING PROTEINS; GLYCAN BINDING AFFINITIES; GLYCOBIOLOGY; GP120 MAN9GLCNAC2; HIV; LECTIN; NUCLEAR MAGNETIC RESONANCE; OLIGOSACCHARIDE INTERACTIONS; SOLUTION NMR DYNAMICS;

CELL ADHESION MOLECULES; HIV; LECTINS, C-TYPE; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOSACCHARIDES; POLYSACCHARIDES; PROTEIN BINDING; RECEPTORS, CELL SURFACE;

EID: 84881261507     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.458299     Document Type: Article

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