-
1
-
-
79955581681
-
Fundamental Structures and Behaviors of Proteins
-
Wang, W. Roberts, C. John Wiley & Sons, Inc. Hoboken, NJ
-
Laurence, J. S.; Middaugh, C. R. Fundamental Structures and Behaviors of Proteins. In Aggregation of Therapeutic Proteins; Wang, W., Roberts, C., Eds.; John Wiley & Sons, Inc.: Hoboken, NJ, 2010; pp 1-62.
-
(2010)
Aggregation of Therapeutic Proteins
, pp. 1-62
-
-
Laurence, J.S.1
Middaugh, C.R.2
-
2
-
-
78650543555
-
Impact of Product-Related Factors on Immunogenicity of Biotherapeutics
-
Singh, S. K. Impact of Product-Related Factors on Immunogenicity of Biotherapeutics J. Pharm. Sci. 2011, 100, 354-387
-
(2011)
J. Pharm. Sci.
, vol.100
, pp. 354-387
-
-
Singh, S.K.1
-
3
-
-
33748041958
-
Effects of Protein Aggregates: An Immunologic Perspective
-
Rosenberg, A. S. Effects of Protein Aggregates: An Immunologic Perspective AAPS J. 2006, 8, E501-E507
-
(2006)
AAPS J.
, vol.8
-
-
Rosenberg, A.S.1
-
4
-
-
79955599896
-
Frozen State Storage Instability of a Monoclonal Antibody: Aggregation as a Consequence of Trehalose Crystallization and Protein Unfolding
-
Singh, S. K.; Kolhe, P.; Mehta, A. P.; Chico, S. C.; Lary, A. L.; Huang, M. Frozen State Storage Instability of a Monoclonal Antibody: Aggregation as a Consequence of Trehalose Crystallization and Protein Unfolding Pharm. Res. 2011, 28, 873-885
-
(2011)
Pharm. Res.
, vol.28
, pp. 873-885
-
-
Singh, S.K.1
Kolhe, P.2
Mehta, A.P.3
Chico, S.C.4
Lary, A.L.5
Huang, M.6
-
5
-
-
0036250675
-
Freezing Biopharmaceuticals Using Common Techniques - And the Magnitude of Bulk-Scale Freeze-Concentration
-
Webb, S. D.; Sesin, D. F.; Kincaid, A. C.; Webb, J. N.; Hughes, T. G. Freezing Biopharmaceuticals Using Common Techniques-And the Magnitude of Bulk-Scale Freeze-Concentration BioPharm Int. 2002, 15, 22-34
-
(2002)
BioPharm Int.
, vol.15
, pp. 22-34
-
-
Webb, S.D.1
Sesin, D.F.2
Kincaid, A.C.3
Webb, J.N.4
Hughes, T.G.5
-
6
-
-
67651202371
-
Freezing-Induced Phase Separation and Spatial Microheterogeneity in Protein Solutions
-
Dong, J.; Hubel, A.; Bischof, J. C.; Aksan, A. Freezing-Induced Phase Separation and Spatial Microheterogeneity in Protein Solutions J. Phys. Chem. B 2009, 113, 10081-10087
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 10081-10087
-
-
Dong, J.1
Hubel, A.2
Bischof, J.C.3
Aksan, A.4
-
7
-
-
77953674463
-
Cold Denaturation of Monoclonal Antibodies
-
Lazar, K. L.; Patapoff, T. W.; Sharma, V. K. Cold Denaturation of Monoclonal Antibodies mAbs 2010, 2, 42-52
-
(2010)
MAbs
, vol.2
, pp. 42-52
-
-
Lazar, K.L.1
Patapoff, T.W.2
Sharma, V.K.3
-
8
-
-
35748979712
-
Protein Stability during Freezing: Separation of Stresses and Mechanisms of Protein Stabilization
-
Bhatnagar, B. S.; Bogner, R. H.; Pikal, M. J. Protein Stability During Freezing: Separation of Stresses and Mechanisms of Protein Stabilization Pharm. Dev. Technol. 2007, 12, 505-523
-
(2007)
Pharm. Dev. Technol.
, vol.12
, pp. 505-523
-
-
Bhatnagar, B.S.1
Bogner, R.H.2
Pikal, M.J.3
-
9
-
-
0036771258
-
Effect of Glycine on pH Changes and Protein Stability during Freeze-Thawing in Phosphate Buffer systems
-
Pikal-Cleland, K. A.; Cleland, J. L.; Anchordoquy, T. J.; Carpenter, J. F. Effect of Glycine on pH Changes and Protein Stability during Freeze-Thawing in Phosphate Buffer systems J. Pharm. Sci. 2002, 91, 1969-1979
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 1969-1979
-
-
Pikal-Cleland, K.A.1
Cleland, J.L.2
Anchordoquy, T.J.3
Carpenter, J.F.4
-
10
-
-
23844447975
-
Mechanism of Protein Stabilization by Sugars during Freeze-Drying and Storage: Native Structure Preservation, Specific Interaction, and/or Immobilization in a Glassy Matrix?
-
Chang, L. L.; Shepherd, D.; Sun, J.; Ouellette, D.; Grant, K. L.; Tang, X. C.; Pikal, M. J. Mechanism of Protein Stabilization by Sugars during Freeze-Drying and Storage: Native Structure Preservation, Specific Interaction, and/or Immobilization in a Glassy Matrix? J. Pharm. Sci. 2005, 94, 1427-1444
-
(2005)
J. Pharm. Sci.
, vol.94
, pp. 1427-1444
-
-
Chang, L.L.1
Shepherd, D.2
Sun, J.3
Ouellette, D.4
Grant, K.L.5
Tang, X.C.6
Pikal, M.J.7
-
11
-
-
79951728885
-
Compacting Proteins: Pros and Cons of Osmolyte-Induced Folding
-
Melo, E. P.; Estrela, N.; Lopes, C.; Matias, A. C.; Tavares, E.; Ochoa-Mendes, V. Compacting Proteins: Pros and Cons of Osmolyte-Induced Folding Curr. Protein Pept. Sci. 2010, 11, 744-751
-
(2010)
Curr. Protein Pept. Sci.
, vol.11
, pp. 744-751
-
-
Melo, E.P.1
Estrela, N.2
Lopes, C.3
Matias, A.C.4
Tavares, E.5
Ochoa-Mendes, V.6
-
12
-
-
0036367093
-
Physical Stabilization of Proteins in Aqueous Solution
-
Carpenter, J. F. Manning, M. C. Kluwer Academic/Plenum Publishers: New York
-
Kendrick, B. S.; Li, T.; Chang, B. S. Physical Stabilization of Proteins in Aqueous Solution. In Rationale Design of Stable Protein Formulations-Theory and Practice; Carpenter, J. F.; Manning, M. C., Eds.; Kluwer Academic/Plenum Publishers: New York, 2002; Vol. 13, pp 61-84.
-
(2002)
Rationale Design of Stable Protein Formulations - Theory and Practice
, vol.13
, pp. 61-84
-
-
Kendrick, B.S.1
Li, T.2
Chang, B.S.3
-
13
-
-
0029198906
-
Solvent Stabilization of Protein Structure
-
Timasheff, S. N. Solvent Stabilization of Protein Structure Methods Mol. Biol. (N. Y., NY) 1995, 40, 253-269
-
(1995)
Methods Mol. Biol. (N. Y., NY)
, vol.40
, pp. 253-269
-
-
Timasheff, S.N.1
-
14
-
-
0036143398
-
Cryoglobulins
-
Ferri, C.; Zignego, A. L.; Pileri, S. A. Cryoglobulins J. Clin. Pathol. 2002, 55, 4-13
-
(2002)
J. Clin. Pathol.
, vol.55
, pp. 4-13
-
-
Ferri, C.1
Zignego, A.L.2
Pileri, S.A.3
-
15
-
-
33751249357
-
Cryoglobulins: An Important but Neglected Clinical Test
-
Shihabi, Z. K. Cryoglobulins: An Important but Neglected Clinical Test Ann. Clin. Lab. Sci. 2006, 36, 395-408
-
(2006)
Ann. Clin. Lab. Sci.
, vol.36
, pp. 395-408
-
-
Shihabi, Z.K.1
-
16
-
-
0031047581
-
Modeling of the Water-Sucrose State Diagram below 0 C
-
Blond, G.; Simatos, D.; Catté, M.; Dussap, C. G.; Gros, J. B. Modeling of the Water-Sucrose State Diagram Below 0 C Carbohydr. Res. 1997, 298, 139-145
-
(1997)
Carbohydr. Res.
, vol.298
, pp. 139-145
-
-
Blond, G.1
Simatos, D.2
Catté, M.3
Dussap, C.G.4
Gros, J.B.5
-
17
-
-
50849128798
-
Viscosity of Concentrated Sucrose and Trehalose Aqueous Solutions Including the Supercooled Regime
-
Longinotti, M. P.; Corti, H. R. Viscosity of Concentrated Sucrose and Trehalose Aqueous Solutions Including the Supercooled Regime J. Phys. Chem. Ref. Data 2008, 37, 1503-1515
-
(2008)
J. Phys. Chem. Ref. Data
, vol.37
, pp. 1503-1515
-
-
Longinotti, M.P.1
Corti, H.R.2
-
18
-
-
0002862399
-
Denaturation of Hemoglobin under High Pressure i
-
Suzuki, K.; Kitamura, K. Denaturation of Hemoglobin under High Pressure I Rev. Phys. Chem. Jpn. 1960, 29, 81-85
-
(1960)
Rev. Phys. Chem. Jpn.
, vol.29
, pp. 81-85
-
-
Suzuki, K.1
Kitamura, K.2
-
19
-
-
0028220701
-
Proteins under Pressure - The Influence of High Hydrostatic Pressure on Structure, Function and Assembly of Proteins and Protein Complexes
-
Gross, M.; Jaenicke, R. Proteins under Pressure-The Influence of High Hydrostatic Pressure on Structure, Function and Assembly of Proteins and Protein Complexes Eur. J. Biochem. 1994, 221, 617-630
-
(1994)
Eur. J. Biochem.
, vol.221
, pp. 617-630
-
-
Gross, M.1
Jaenicke, R.2
-
20
-
-
0012223420
-
High Pressure and Protein Oligomeric Dissociation
-
Balny, C. High Pressure and Protein Oligomeric Dissociation High Pressure Res. 2002, 22, 737-741
-
(2002)
High Pressure Res.
, vol.22
, pp. 737-741
-
-
Balny, C.1
-
21
-
-
24344491042
-
High-Pressure Studies of Aggregation of Recombinant Human Interleukin-1 Receptor Antagonist: Thermodynamics, Kinetics, and Application to Accelerated Formulation Studies
-
Seefeldt, M. B.; Kim, Y. S.; Tolley, K. P.; Seely, J.; Carpenter, J. F.; Randolph, T. W. High-Pressure Studies of Aggregation of Recombinant Human Interleukin-1 Receptor Antagonist: Thermodynamics, Kinetics, and Application to Accelerated Formulation Studies Protein Sci. 2005, 14, 2258-2266
-
(2005)
Protein Sci.
, vol.14
, pp. 2258-2266
-
-
Seefeldt, M.B.1
Kim, Y.S.2
Tolley, K.P.3
Seely, J.4
Carpenter, J.F.5
Randolph, T.W.6
-
22
-
-
0008823209
-
Pressure-Assisted Cold Unfolding of Proteins and Its Effects on the Conformational Stability Compared to Pressure and Heat Unfolding
-
Meersman, F.; Smeller, L.; Heremans, K. Pressure-Assisted Cold Unfolding of Proteins and Its Effects on the Conformational Stability Compared to Pressure and Heat Unfolding High Pressure Res. 2000, 19, 263-268
-
(2000)
High Pressure Res.
, vol.19
, pp. 263-268
-
-
Meersman, F.1
Smeller, L.2
Heremans, K.3
-
23
-
-
59349083966
-
Protein Aggregation Kinetics, Mechanism, and Curve-Fitting: A Review of the Literature
-
Morris, A. M.; Watzky, M. A.; Finke, R. G. Protein Aggregation Kinetics, Mechanism, and Curve-Fitting: A Review of the Literature Biochim. Biophys. Acta 2009, 1794, 375-397
-
(2009)
Biochim. Biophys. Acta
, vol.1794
, pp. 375-397
-
-
Morris, A.M.1
Watzky, M.A.2
Finke, R.G.3
-
24
-
-
15544363358
-
Unfolding, Aggregation, and Seeded Amyloid Formation of Lysine-58-Cleaved Beta 2-Microglobulin
-
Heegaard, N. H.; Jorgensen, T. J.; Rozlosnik, N.; Corlin, D. B.; Pedersen, J. S.; Tempesta, A. G.; Roepstorff, P.; Bauer, R.; Nissen, M. H. Unfolding, Aggregation, and Seeded Amyloid Formation of Lysine-58-Cleaved Beta 2-Microglobulin Biochemistry 2005, 44, 4397-4407
-
(2005)
Biochemistry
, vol.44
, pp. 4397-4407
-
-
Heegaard, N.H.1
Jorgensen, T.J.2
Rozlosnik, N.3
Corlin, D.B.4
Pedersen, J.S.5
Tempesta, A.G.6
Roepstorff, P.7
Bauer, R.8
Nissen, M.H.9
-
25
-
-
0036070790
-
Thermal Denaturation of Bungarus fasciatus Acetylcholinesterase: Is Aggregation a Driving Force in Protein Unfolding?
-
Shin, I.; Wachtel, E.; Roth, E.; Bon, C.; Silman, I.; Weiner, L. Thermal Denaturation of Bungarus fasciatus Acetylcholinesterase: Is Aggregation a Driving Force in Protein Unfolding? Protein Sci. 2002, 11, 2022-2032
-
(2002)
Protein Sci.
, vol.11
, pp. 2022-2032
-
-
Shin, I.1
Wachtel, E.2
Roth, E.3
Bon, C.4
Silman, I.5
Weiner, L.6
-
26
-
-
0037421836
-
Kinetics of Irreversible Protein Aggregation: Analysis of Extended Lumry-Eyring Models and Implications for Predicting Protein Shelf Life
-
Roberts, C. J. Kinetics of Irreversible Protein Aggregation: Analysis of Extended Lumry-Eyring Models and Implications for Predicting Protein Shelf Life J. Phys. Chem. B 2003, 107, 1194-1207
-
(2003)
J. Phys. Chem. B
, vol.107
, pp. 1194-1207
-
-
Roberts, C.J.1
-
27
-
-
67650072650
-
Lumry-Eyring Nucleated-Polymerization Model of Protein Aggregation Kinetics: 2. Competing Growth via Condensation and Chain Polymerization
-
Li, Y.; Roberts, C. J. Lumry-Eyring Nucleated-Polymerization Model of Protein Aggregation Kinetics: 2. Competing Growth via Condensation and Chain Polymerization J. Phys. Chem. B 2009, 113, 7020-7032
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 7020-7032
-
-
Li, Y.1
Roberts, C.J.2
-
28
-
-
34250834054
-
A Lumry-Eyring Nucleated Polymerization Model of Protein Aggregation Kinetics: 1. Aggregation with Pre-Equilibrated Unfolding
-
Andrews, J. M.; Roberts, C. J. A Lumry-Eyring Nucleated Polymerization Model of Protein Aggregation Kinetics: 1. Aggregation with Pre-Equilibrated Unfolding J. Phys. Chem. B 2007, 11, 7897-7913
-
(2007)
J. Phys. Chem. B
, vol.11
, pp. 7897-7913
-
-
Andrews, J.M.1
Roberts, C.J.2
-
29
-
-
64549100352
-
Tangential Flow Filtration of Hemoglobin
-
Palmer, A. F.; Sun, G.; Harris, D. R. Tangential Flow Filtration of Hemoglobin Biotechnol. Prog. 2009, 25, 189-199
-
(2009)
Biotechnol. Prog.
, vol.25
, pp. 189-199
-
-
Palmer, A.F.1
Sun, G.2
Harris, D.R.3
-
30
-
-
0029937808
-
Recommendations for Reference Method for Haemoglobinometry in Human Blood (ICSH Standard 1995) and Specifications for International Haemiglobinocyanide Standard (4th Edition)
-
Zwart, A.; van Assendelft, O. W.; Bull, B. S.; England, J. M.; Lewis, S. M.; Zijlstra, W. G. Recommendations for Reference Method for Haemoglobinometry in Human Blood (ICSH Standard 1995) and Specifications for International Haemiglobinocyanide Standard (4th Edition) J. Clin. Pathol. 1996, 49, 271-274
-
(1996)
J. Clin. Pathol.
, vol.49
, pp. 271-274
-
-
Zwart, A.1
Van Assendelft, O.W.2
Bull, B.S.3
England, J.M.4
Lewis, S.M.5
Zijlstra, W.G.6
-
31
-
-
0001962269
-
Principle of "cryostabilization" Technology from Structure/Property Relationships of Carbohydrate/Water Systems-A Review
-
Levine, H.; Slade, L. Principle of "Cryostabilization" Technology from Structure/Property Relationships of Carbohydrate/Water Systems-A Review CryoLetters 1988, 9, 21-63
-
(1988)
CryoLetters
, vol.9
, pp. 21-63
-
-
Levine, H.1
Slade, L.2
-
32
-
-
0842302347
-
Trehalose-Enzyme Interactions Result in Structure Stabilization and Activity Inhibition. The Role of Viscosity
-
Sampedro, J. G.; Uribe, S. Trehalose-Enzyme Interactions Result in Structure Stabilization and Activity Inhibition. The Role of Viscosity Mol. Cell. Biochem. 2004, 256, 319-327
-
(2004)
Mol. Cell. Biochem.
, vol.256
, pp. 319-327
-
-
Sampedro, J.G.1
Uribe, S.2
-
33
-
-
0023905575
-
The Mechanism of Cryoprotection of Proteins by Solutes
-
Carpenter, J. F.; Crowe, J. H. The Mechanism of Cryoprotection of Proteins by Solutes Cryobiology 1988, 25, 244-255
-
(1988)
Cryobiology
, vol.25
, pp. 244-255
-
-
Carpenter, J.F.1
Crowe, J.H.2
-
34
-
-
0019888281
-
The Stabilization of Proteins by Sucrose
-
Lee, J. C.; Thimaseff, S. N. The Stabilization of Proteins by Sucrose J. Biol. Chem. 1981, 256, 7193-7201
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 7193-7201
-
-
Lee, J.C.1
Thimaseff, S.N.2
-
36
-
-
84874723211
-
Frozen-State Storage Stability of a Monoclonal Antibody: Aggregation is Impacted by Freezing Rate and Solute Distribution
-
Miller, M. A.; Rodrigues, M. A.; Glass, M. A.; Singh, S. K.; Johnston, K. P.; Maynard, J. A. Frozen-State Storage Stability of a Monoclonal Antibody: Aggregation is Impacted by Freezing Rate and Solute Distribution J. Pharm. Sci. 2013, 102, 1194-1208
-
(2013)
J. Pharm. Sci.
, vol.102
, pp. 1194-1208
-
-
Miller, M.A.1
Rodrigues, M.A.2
Glass, M.A.3
Singh, S.K.4
Johnston, K.P.5
Maynard, J.A.6
-
37
-
-
56449087972
-
The Hyperthermophilic Nature of the Metallo-Oxidase from Aquifex aeolicus
-
Fernandes, A. T.; Martins, L. O.; Melo, E. P. The Hyperthermophilic Nature of the Metallo-Oxidase from Aquifex aeolicus Biochim. Biophys. Acta 2009, 1794, 75-83
-
(2009)
Biochim. Biophys. Acta
, vol.1794
, pp. 75-83
-
-
Fernandes, A.T.1
Martins, L.O.2
Melo, E.P.3
-
38
-
-
0034694819
-
Trehalose Delays the Reversible but Not the Irreversible Thermal Denaturation of Cutinase
-
Baptista, R. P.; Cabral, J. M.; Melo, E. P. Trehalose Delays the Reversible but Not the Irreversible Thermal Denaturation of Cutinase Biotechnol. Bioeng. 2000, 70, 699-703
-
(2000)
Biotechnol. Bioeng.
, vol.70
, pp. 699-703
-
-
Baptista, R.P.1
Cabral, J.M.2
Melo, E.P.3
|