메뉴 건너뛰기




Volumn 25, Issue , 2012, Pages 268-283

Mechanism of parathyroid hormone-mediated suppression of calcification markers in human intervertebral disc cells

Author keywords

Disc calcification; Gene expression; Intervertebral disc degeneration; Mitogen activated protein kinase; Parathyroid hormone; Type II collagen; Type X collagen

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ALKALINE PHOSPHATASE; CALCIUM ION; COLLAGEN TYPE 10; COLLAGEN TYPE 2; MITOGEN ACTIVATED PROTEIN KINASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PARATHYROID HORMONE RECEPTOR 1; PARATHYROID HORMONE[1-34]; PHOSPHATE;

EID: 84881243405     PISSN: 14732262     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (21)

References (47)
  • 1
    • 33747355707 scopus 로고    scopus 로고
    • What is intervertebral disc degeneration, and what causes it?
    • (Phila Pa 1976)
    • Adams MA, Roughley PJ (2006) What is intervertebral disc degeneration, and what causes it? Spine (Phila Pa 1976) 31: 2151-2161.
    • (2006) Spine , vol.31 , pp. 2151-2161
    • Adams, M.A.1    Roughley, P.J.2
  • 2
    • 0029813162 scopus 로고    scopus 로고
    • The human lumbar intervertebral disc: Evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration
    • Antoniou J, Steffen T, Nelson F, Winterbottom N, Hollander AP, Poole RA, Aebi M, Alini M (1996) The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration. J Clin Invest 98: 996-1003.
    • (1996) J Clin Invest , vol.98 , pp. 996-1003
    • Antoniou, J.1    Steffen, T.2    Nelson, F.3    Winterbottom, N.4    Hollander, A.P.5    Poole, R.A.6    Aebi, M.7    Alini, M.8
  • 3
    • 84863146922 scopus 로고    scopus 로고
    • Parathyroid hormone treatment improves the cortical bone micro-structure by improving the distribution of type I collagen in postmenopausal women with osteoporosis
    • Ascenzi MG, Liao VP, Lee BM, Billi F, Zhou H, Lindsay R, Cosman F, Nieves J, Bilezkian JP, Dempster DW (2012) Parathyroid hormone treatment improves the cortical bone micro-structure by improving the distribution of type I collagen in postmenopausal women with osteoporosis. J Bone Miner Res 27: 702-712.
    • (2012) J Bone Miner Res , vol.27 , pp. 702-712
    • Ascenzi, M.G.1    Liao, V.P.2    Lee, B.M.3    Billi, F.4    Zhou, H.5    Lindsay, R.6    Cosman, F.7    Nieves, J.8    Bilezkian, J.P.9    Dempster, D.W.10
  • 4
    • 0025941878 scopus 로고
    • Thrombin and parathyroid hormone mobilize intracellular calcium in rat osteosarcoma cells by distinct pathways
    • Babich M, Choi H, Johnson RM, King KL, Alford GE, Nissenson RA (1991) Thrombin and parathyroid hormone mobilize intracellular calcium in rat osteosarcoma cells by distinct pathways. Endocrinology 129: 1463-1470.
    • (1991) Endocrinology , vol.129 , pp. 1463-1470
    • Babich, M.1    Choi, H.2    Johnson, R.M.3    King, K.L.4    Alford, G.E.5    Nissenson, R.A.6
  • 5
    • 16544367542 scopus 로고    scopus 로고
    • Cell viability and the physical environment in the scoliotic intervertebral disc
    • Bibby SR, Meir A, Fairbank JC, Urban JP (2002) Cell viability and the physical environment in the scoliotic intervertebral disc. Stud Health Technol Inform 91: 419-421.
    • (2002) Stud Health Technol Inform , vol.91 , pp. 419-421
    • Bibby, S.R.1    Meir, A.2    Fairbank, J.C.3    Urban, J.P.4
  • 6
    • 0026235255 scopus 로고
    • The lumbar disc and low back pain
    • Bogduk N (1991) The lumbar disc and low back pain. Neurosurg Clin N Am 2: 791-806.
    • (1991) Neurosurg Clin N Am , vol.2 , pp. 791-806
    • Bogduk, N.1
  • 7
    • 0031438388 scopus 로고    scopus 로고
    • Immunolocalization of type X collagen in human lumbar intervertebral discs during ageing and degeneration
    • Boos N, Nerlich AG, Wiest I, von der Mark K, Aebi M (1997) Immunolocalization of type X collagen in human lumbar intervertebral discs during ageing and degeneration. Histochem Cell Biol 108: 471-480.
    • (1997) Histochem Cell Biol , vol.108 , pp. 471-480
    • Boos, N.1    Nerlich, A.G.2    Wiest, I.3    von der Mark, K.4    Aebi, M.5
  • 8
    • 0036894572 scopus 로고    scopus 로고
    • Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science
    • (Phila Pa 1976)
    • Boos N, Weissbach S, Rohrbach H, Weiler C, Spratt KF, Nerlich AG (2002) Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science. Spine (Phila Pa 1976) 27: 2631-2644.
    • (2002) Spine , Issue.27 , pp. 2631-2644
    • Boos, N.1    Weissbach, S.2    Rohrbach, H.3    Weiler, C.4    Spratt, K.F.5    Nerlich, A.G.6
  • 9
    • 0029008944 scopus 로고
    • Aging and degeneration of the human intervertebral disc
    • (Phila Pa 1976)
    • Buckwalter JA (1995) Aging and degeneration of the human intervertebral disc. Spine (Phila Pa 1976) 20: 1307-1314.
    • (1995) Spine , Issue.20 , pp. 1307-1314
    • Buckwalter, J.A.1
  • 10
    • 84862770811 scopus 로고    scopus 로고
    • Design, conformational studies and analysis of structure-function relationships of PTH (1-11) analogues: The essential role of Val in position 2
    • Caporale A, Gesiot L, Sturlese M, Wittelsberger A, Mammi S, Peggion E (2012) Design, conformational studies and analysis of structure-function relationships of PTH (1-11) analogues: the essential role of Val in position 2. Amino Acids 43: 207-218.
    • (2012) Amino Acids , vol.43 , pp. 207-218
    • Caporale, A.1    Gesiot, L.2    Sturlese, M.3    Wittelsberger, A.4    Mammi, S.5    Peggion, E.6
  • 11
  • 12
    • 0028951238 scopus 로고
    • Identification of heterogeneous cell populations in normal human intervertebral disc
    • Chelberg MK, Banks GM, Geiger DF, Oegema TR Jr (1995) Identification of heterogeneous cell populations in normal human intervertebral disc. J Anat 186: 43-53.
    • (1995) J Anat , vol.186 , pp. 43-53
    • Chelberg, M.K.1    Banks, G.M.2    Geiger, D.F.3    Oegema Jr., T.R.4
  • 13
    • 0024263042 scopus 로고
    • PTH elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line
    • Civitelli R, Reid IR, Westbrook S, Avioli LV, Hruska KA (1988) PTH elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line. Am J Physiol 255: E660-667.
    • (1988) Am J Physiol , vol.255
    • Civitelli, R.1    Reid, I.R.2    Westbrook, S.3    Avioli, L.V.4    Hruska, K.A.5
  • 14
    • 0035574614 scopus 로고    scopus 로고
    • Regulatory mechanisms in the pathways of cartilage and bone formation
    • De Crombrugghe B, Lefebvre V, Nakashima K (2001) Regulatory mechanisms in the pathways of cartilage and bone formation. Curr Opin Cell Biol 13: 721-727.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 721-727
    • de Crombrugghe, B.1    Lefebvre, V.2    Nakashima, K.3
  • 16
    • 0029116964 scopus 로고
    • Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells
    • Dobnig H, Turner RT (1995) Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells. Endocrinology 136: 3632-3638.
    • (1995) Endocrinology , vol.136 , pp. 3632-3638
    • Dobnig, H.1    Turner, R.T.2
  • 17
    • 54049090502 scopus 로고    scopus 로고
    • Calcium phosphate crystals induce cell death in human vascular smooth muscle cells: A potential mechanism in atherosclerotic plaque destabilization
    • Ewence AE, Bootman M, Roderick HL, Skepper JN, McCarthy G, Epple M, Neumann M, Shanahan CM, Proudfoot D (2008) Calcium phosphate crystals induce cell death in human vascular smooth muscle cells: a potential mechanism in atherosclerotic plaque destabilization. Circ Res 103: e28-34.
    • (2008) Circ Res , vol.103
    • Ewence, A.E.1    Bootman, M.2    Roderick, H.L.3    Skepper, J.N.4    McCarthy, G.5    Epple, M.6    Neumann, M.7    Shanahan, C.M.8    Proudfoot, D.9
  • 18
    • 57349105550 scopus 로고    scopus 로고
    • The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain
    • Freemont AJ (2009) The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain. Rheumatology (Oxford) 48: 5-10.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 5-10
    • Freemont, A.J.1
  • 19
    • 0032055960 scopus 로고    scopus 로고
    • Analysis of aging and degeneration of the human intervertebral disc. Comparison of surgical specimens with normal controls
    • (Phila Pa 1976)
    • Gruber HE, Hanley EN Jr (1998) Analysis of aging and degeneration of the human intervertebral disc. Comparison of surgical specimens with normal controls. Spine (Phila Pa 1976) 23: 751-757.
    • (1998) Spine , Issue.23 , pp. 751-757
    • Gruber, H.E.1    Hanley Jr., E.N.2
  • 20
    • 10044264297 scopus 로고    scopus 로고
    • Chondrocyte terminal differentiation, apoptosis, and type X collagen expression are downregulated by parathyroid hormone
    • Harrington EK, Lunsford LE, Svoboda KK (2004) Chondrocyte terminal differentiation, apoptosis, and type X collagen expression are downregulated by parathyroid hormone. Anat Rec (Hoboken) 281:1286-1295.
    • (2004) Anat Rec (Hoboken) , vol.281 , pp. 1286-1295
    • Harrington, E.K.1    Lunsford, L.E.2    Svoboda, K.K.3
  • 21
    • 76149085502 scopus 로고    scopus 로고
    • PTH stimulated growth and decreased Col-X deposition are phosphotidylinositol-3,4,5 triphosphate kinase and mitogen activating protein kinase dependent in avian sterna
    • Harrington EK, Coon DJ, Kern MF, Svoboda KK (2010) PTH stimulated growth and decreased Col-X deposition are phosphotidylinositol-3,4,5 triphosphate kinase and mitogen activating protein kinase dependent in avian sterna. Anat Rec (Hoboken) 293: 225-234.
    • (2010) Anat Rec (Hoboken) , vol.293 , pp. 225-234
    • Harrington, E.K.1    Coon, D.J.2    Kern, M.F.3    Svoboda, K.K.4
  • 22
    • 0035040548 scopus 로고    scopus 로고
    • Extracellular matrix in development of the intervertebral disc
    • Hayes AJ, Benjamin M, Ralphs JR (2001) Extracellular matrix in development of the intervertebral disc. Matrix Biol 20: 107-121.
    • (2001) Matrix Biol , vol.20 , pp. 107-121
    • Hayes, A.J.1    Benjamin, M.2    Ralphs, J.R.3
  • 24
    • 0030950116 scopus 로고    scopus 로고
    • Effects of calcitonin and parathyroid hormone on calcification of primary cultures of chicken growth plate chondrocytes
    • Ishikawa Y, Wu LN, Genge BR, Mwale F, Wuthier RE (1997) Effects of calcitonin and parathyroid hormone on calcification of primary cultures of chicken growth plate chondrocytes. J Bone Miner Res 12: 356-366.
    • (1997) J Bone Miner Res , vol.12 , pp. 356-366
    • Ishikawa, Y.1    Wu, L.N.2    Genge, B.R.3    Mwale, F.4    Wuthier, R.E.5
  • 25
    • 0041352137 scopus 로고    scopus 로고
    • Parathyroid hormone (PTH) down-regulates PTH/PTH-related protein receptor gene expression in UMR-106 osteoblast-like cells via a 3',5'-cyclic adenosine monophosphate-dependent, protein kinase A-independent pathway
    • Kawane T, Mimura J, Yanagawa T, Fujii-Kuriyama Y, Horiuchi N (2003) Parathyroid hormone (PTH) down-regulates PTH/PTH-related protein receptor gene expression in UMR-106 osteoblast-like cells via a 3',5'-cyclic adenosine monophosphate-dependent, protein kinase A-independent pathway. J Endocrinol 178: 247-256.
    • (2003) J Endocrinol , vol.178 , pp. 247-256
    • Kawane, T.1    Mimura, J.2    Yanagawa, T.3    Fujii-Kuriyama, Y.4    Horiuchi, N.5
  • 26
    • 23044507489 scopus 로고    scopus 로고
    • New perspectives on parathyroid hormone therapy
    • Lane N, Morris S (2005) New perspectives on parathyroid hormone therapy. Curr Opin Rheumatol 17:467-474.
    • (2005) Curr Opin Rheumatol , vol.17 , pp. 467-474
    • Lane, N.1    Morris, S.2
  • 27
    • 0034846904 scopus 로고    scopus 로고
    • L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway
    • Lefebvre V, Behringer RR, de Crombrugghe B (2001) L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. Osteoarthritis Cartilage 9 Suppl A: S69-75.
    • (2001) Osteoarthritis Cartilage , vol.9 , Issue.SUPPL. A
    • Lefebvre, V.1    Behringer, R.R.2    de Crombrugghe, B.3
  • 28
    • 79952100061 scopus 로고    scopus 로고
    • Degenerative disc disease of herniated intervertebral discs is associated with extracellular matrix remodeling, vimentin-positive cells and cell death
    • Loreto C, Musumeci G, Castorina A, Martinez G (2011) Degenerative disc disease of herniated intervertebral discs is associated with extracellular matrix remodeling, vimentin-positive cells and cell death. Ann Anat 193: 156-162.
    • (2011) Ann Anat , vol.193 , pp. 156-162
    • Loreto, C.1    Musumeci, G.2    Castorina, A.3    Martinez, G.4
  • 30
    • 0020324495 scopus 로고
    • Alkaline phosphatase inhibition by parathyroid hormone and isoproterenol in a clonal rat osteosarcoma cell line. Possible mediation by cyclic AMP
    • Majeska RJ, Rodan GA (1982) Alkaline phosphatase inhibition by parathyroid hormone and isoproterenol in a clonal rat osteosarcoma cell line. Possible mediation by cyclic AMP. Calcif Tissue Int 34: 59-66.
    • (1982) Calcif Tissue Int , vol.34 , pp. 59-66
    • Majeska, R.J.1    Rodan, G.A.2
  • 31
    • 78149253233 scopus 로고    scopus 로고
    • Effect of parathyroid hormone on type X and type II collagen expression in mesenchymal stem cells from osteoarthritic patients
    • Mwale F, Yao G, Ouellet JA, Petit A, Antoniou J (2010) Effect of parathyroid hormone on type X and type II collagen expression in mesenchymal stem cells from osteoarthritic patients. Tissue Eng Part A 16: 3449-3455.
    • (2010) Tissue Eng Part A , vol.16 , pp. 3449-3455
    • Mwale, F.1    Yao, G.2    Ouellet, J.A.3    Petit, A.4    Antoniou, J.5
  • 32
    • 0027220026 scopus 로고
    • Biochemistry of the intervertebral disc
    • Oegema TR Jr (1993) Biochemistry of the intervertebral disc. Clin Sports Med 12: 419-439.
    • (1993) Clin Sports Med , vol.12 , pp. 419-439
    • Oegema Jr., T.R.1
  • 34
    • 76249113874 scopus 로고    scopus 로고
    • The mechanism of mineralization and the role of alkaline phosphatase in health and disease
    • Orimo H (2010) The mechanism of mineralization and the role of alkaline phosphatase in health and disease. J Nihon Med Sch 77: 4-12.
    • (2010) J Nihon Med Sch , vol.77 , pp. 4-12
    • Orimo, H.1
  • 35
    • 0028341473 scopus 로고
    • Signal transduction pathways mediating parathyroid hormone regulation of osteoblastic gene expression
    • Partridge NC, Bloch SR, Pearman AT (1994) Signal transduction pathways mediating parathyroid hormone regulation of osteoblastic gene expression. J Cell Biochem 55: 321-327.
    • (1994) J Cell Biochem , vol.55 , pp. 321-327
    • Partridge, N.C.1    Bloch, S.R.2    Pearman, A.T.3
  • 37
    • 0027670543 scopus 로고
    • The cartilage end-plate and intervertebral disc in scoliosis: Calcification and other sequelae
    • Roberts S, Menage J, Eisenstein SM (1993) The cartilage end-plate and intervertebral disc in scoliosis: calcification and other sequelae. J Orthop Res 11: 747-757.
    • (1993) J Orthop Res , vol.11 , pp. 747-757
    • Roberts, S.1    Menage, J.2    Eisenstein, S.M.3
  • 39
    • 0032835840 scopus 로고    scopus 로고
    • Anabolic or catabolic responses of MC3T3-E1 osteoblastic cells to parathyroid hormone depend on time and duration of treatment
    • Schiller PC, D'Ippolito G, Roos BA, Howard GA (1999) Anabolic or catabolic responses of MC3T3-E1 osteoblastic cells to parathyroid hormone depend on time and duration of treatment. J Bone Miner Res 14: 1504-1512.
    • (1999) J Bone Miner Res , vol.14 , pp. 1504-1512
    • Schiller, P.C.1    D'Ippolito, G.2    Roos, B.A.3    Howard, G.A.4
  • 40
    • 70349772002 scopus 로고    scopus 로고
    • Endogenous parathyroid hormone-related protein regulates the expression of PTH type 1 receptor and proliferation of vascular smooth muscle cells
    • Song GJ, Fiaschi-Taesch N, Bisello A (2009) Endogenous parathyroid hormone-related protein regulates the expression of PTH type 1 receptor and proliferation of vascular smooth muscle cells. Mol Endocrinol 23: 1681-1690.
    • (2009) Mol Endocrinol , vol.23 , pp. 1681-1690
    • Song, G.J.1    Fiaschi-Taesch, N.2    Bisello, A.3
  • 41
    • 34948899776 scopus 로고    scopus 로고
    • Regulation of matrix Gla protein by parathyroid hormone in MC3T3-E1 osteoblast-like cells involves protein kinase A and extracellular signal-regulated kinase pathways
    • Suttamanatwong S, Franceschi RT, Carlson AE, Gopalakrishnan R (2007) Regulation of matrix Gla protein by parathyroid hormone in MC3T3-E1 osteoblast-like cells involves protein kinase A and extracellular signal-regulated kinase pathways. J Cell Biochem 102: 496-505.
    • (2007) J Cell Biochem , vol.102 , pp. 496-505
    • Suttamanatwong, S.1    Franceschi, R.T.2    Carlson, A.E.3    Gopalakrishnan, R.4
  • 42
    • 0035831498 scopus 로고    scopus 로고
    • Stimulation of extracellular signal-regulated kinases and proliferation in rat osteoblastic cells by parathyroid hormone is protein kinase C-dependent
    • Swarthout JT, Doggett TA, Lemker JL, Partridge NC (2001) Stimulation of extracellular signal-regulated kinases and proliferation in rat osteoblastic cells by parathyroid hormone is protein kinase C-dependent. J Biol Chem 276: 7586-7592.
    • (2001) J Biol Chem , vol.276 , pp. 7586-7592
    • Swarthout, J.T.1    Doggett, T.A.2    Lemker, J.L.3    Partridge, N.C.4
  • 43
    • 0037045407 scopus 로고    scopus 로고
    • Parathyroid hormone-dependent signaling pathways regulating genes in bone cells
    • Swarthout JT, D'Alonzo RC, Selvamurugan N, Partridge NC (2002) Parathyroid hormone-dependent signaling pathways regulating genes in bone cells. Gene 282: 1-17.
    • (2002) Gene , vol.282 , pp. 1-17
    • Swarthout, J.T.1    D'Alonzo, R.C.2    Selvamurugan, N.3    Partridge, N.C.4
  • 44
    • 33646030271 scopus 로고    scopus 로고
    • Intermittent parathyroid hormone therapy to increase bone formation
    • Thomas T (2006) Intermittent parathyroid hormone therapy to increase bone formation. Joint Bone Spine 73: 262-269.
    • (2006) Joint Bone Spine , vol.73 , pp. 262-269
    • Thomas, T.1
  • 45
    • 0025332891 scopus 로고
    • Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc
    • (Phila Pa 1976)
    • Thompson JP, Pearce RH, Schechter MT, Adams ME, Tsang IK, Bishop PB (1990) Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc. Spine (Phila Pa 1976) 15: 411-415.
    • (1990) Spine , Issue.15 , pp. 411-415
    • Thompson, J.P.1    Pearce, R.H.2    Schechter, M.T.3    Adams, M.E.4    Tsang, I.K.5    Bishop, P.B.6
  • 46
    • 0035871248 scopus 로고    scopus 로고
    • Electrochemical measurement of transport into scoliotic intervertebral discs ex vivo using nitrous oxide as a tracer
    • (Phila Pa 1976)
    • Urban MR, Fairbank JC, Etherington PJ, Loh FL, Winlove CP, Urban JP (2001) Electrochemical measurement of transport into scoliotic intervertebral discs ex vivo using nitrous oxide as a tracer. Spine (Phila Pa 1976) 26: 984-990.
    • (2001) Spine , Issue.26 , pp. 984-990
    • Urban, M.R.1    Fairbank, J.C.2    Etherington, P.J.3    Loh, F.L.4    Winlove, C.P.5    Urban, J.P.6
  • 47
    • 0038729670 scopus 로고    scopus 로고
    • Measurement of the millisecond activation switch of G protein-coupled receptors in living cells
    • Vilardaga JP, Bunemann M, Krasel C, Castro M, Lohse MJ (2003) Measurement of the millisecond activation switch of G protein-coupled receptors in living cells. Nat Biotechnol 21: 807-812.
    • (2003) Nat Biotechnol , vol.21 , pp. 807-812
    • Vilardaga, J.P.1    Bunemann, M.2    Krasel, C.3    Castro, M.4    Lohse, M.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.