메뉴 건너뛰기




Volumn 125, Issue 11, 2013, Pages 513-520

Mineralocorticoid receptors modulate vascular endothelial function in human obesity

Author keywords

Abdominal visceral and subcutaneous fat; Brachial artery; Flow mediated dilation; Mineralocorticoid receptor; Obesity

Indexed keywords

3 NITROTYROSINE; EPLERENONE; ISOPROSTANE DERIVATIVE; MINERALOCORTICOID RECEPTOR; PLACEBO; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

EID: 84881233385     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20130200     Document Type: Article
Times cited : (37)

References (46)
  • 1
    • 67749129442 scopus 로고    scopus 로고
    • Obesity and overweight fact
    • World Health Organization, Fact Sheet No. 311
    • World Health Organization (2013) Obesity and overweight fact, Fact Sheet No. 311, http://www.who.int/mediacentre/ factsheets/fs311/en/
    • (2013)
  • 2
    • 84862005859 scopus 로고    scopus 로고
    • Prevalence of obesity in the United States
    • 2009-2010. NCHS Data Brief
    • Ogden, C. L., Carroll, M. D., Kit, B. K. and Flegal, K. M. (2012) Prevalence of obesity in the United States, 2009-2010. NCHS Data Brief, pp. 1-8
    • (2012) , pp. 1-8
    • Ogden, C.L.1    Carroll, M.D.2    Kit, B.F.3    Flegal, K.M.4
  • 3
    • 33644850953 scopus 로고    scopus 로고
    • Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism
    • Poirier, P., Giles, T. D., Bray, G. A., Hong, Y., Stern, J. S., Pi-Sunyer, F. X. and Eckel, R. H. (2006) Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 113, 898-918
    • (2006) Circulation , vol.113 , pp. 898-918
    • Poirier, P.1    Giles, T.D.2    Bray, G.A.3    Hong, Y.4    Stern, J.S.5    Pi-Sunyer, F.X.6    Eckel, R.H.7
  • 4
    • 80054975039 scopus 로고    scopus 로고
    • Eplerenone survival benefits in heart failure patients post-myocardial infarction are independent from its diuretic and potassium-sparing effects.Insights from an EPHESUS (Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study) substudy.
    • Rossignol, P., Menard, J., Fay, R., Gustafsson, F., Pitt, B. and Zannad, F. (2011) Eplerenone survival benefits in heart failure patients post-myocardial infarction are independent from its diuretic and potassium-sparing effects. Insights from an EPHESUS (Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study) substudy. J. Am. Coll. Cardiol. 58, 1958-1966
    • (2011) J. Am. Coll. Cardiol. , vol.58 , pp. 1958-1966
    • Rossignol, P.1    Menard, J.2    Fay, R.3    Gustafsson, F.4    Pitt, B.5    Zannad, F.6
  • 6
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure.Randomized Aldactone Evaluation Study Investigators.
    • Pitt, B., Zannad, F., Remme, W. J., Cody, R., Castaigne, A., Perez, A., Palensky, J. and Wittes, J. (1999) The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N. Engl. J. Med. 341, 709-717
    • (1999) N. Engl. J. Med. , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6    Palensky, J.7    Wittes, J.8
  • 7
    • 21244485420 scopus 로고    scopus 로고
    • Aldosterone biosynthesis, regulation, and classical mechanism of action
    • Williams, G. H. (2005) Aldosterone biosynthesis, regulation, and classical mechanism of action. Heart Fail. Rev. 10, 7-13
    • (2005) Heart Fail. Rev. , vol.10 , pp. 7-13
    • Williams, G.H.1
  • 8
    • 84856325649 scopus 로고    scopus 로고
    • Mineralocorticoid receptors in vascular function and disease
    • McCurley, A. and Jaffe, I. Z. (2012) Mineralocorticoid receptors in vascular function and disease. Mol. Cell. Endocrinol. 350, 256-265
    • (2012) Mol. Cell. Endocrinol. , vol.350 , pp. 256-265
    • McCurley, A.1    Jaffe, I.Z.2
  • 9
    • 80051931949 scopus 로고    scopus 로고
    • Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors
    • Nguyen Dinh Cat, A., Briones, A. M., Callera, G. E., Yogi, A., He, Y., Montezano, A. C. and Touyz, R. M. (2011) Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors. Hypertension 58, 479-488
    • (2011) Hypertension , vol.58 , pp. 479-488
    • Nguyen Dinh Cat, A.1    Briones, A.M.2    Callera, G.E.3    Yogi, A.4    He, Y.5    Montezano, A.C.6    Touyz, R.M.7
  • 10
  • 12
    • 70450225065 scopus 로고    scopus 로고
    • Aldosterone contributes to blood pressure variance and to likelihood of hypertension in normal-weight and overweight African Americans
    • Kidambi, S., Kotchen, J. M., Krishnaswami, S., Grim, C. E. and Kotchen, T. A. (2009) Aldosterone contributes to blood pressure variance and to likelihood of hypertension in normal-weight and overweight African Americans. Am. J. Hypertens. 22, 1303-1308
    • (2009) Am. J. Hypertens. , vol.22 , pp. 1303-1308
    • Kidambi, S.1    Kotchen, J.M.2    Krishnaswami, S.3    Grim, C.E.4    Kotchen, T.A.5
  • 17
    • 0019424146 scopus 로고
    • The effect of weight reduction on blood pressure, plasma renin activity, and plasma aldosterone levels in obese patients
    • Tuck, M. L., Sowers, J., Dornfeld, L., Kledzik, G. and Maxwell, M. (1981) The effect of weight reduction on blood pressure, plasma renin activity, and plasma aldosterone levels in obese patients. N. Engl. J. Med. 304, 930-933
    • (1981) N. Engl. J. Med. , vol.304 , pp. 930-933
    • Tuck, M.L.1    Sowers, J.2    Dornfeld, L.3    Kledzik, G.4    Maxwell, M.5
  • 19
    • 60349087302 scopus 로고    scopus 로고
    • Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity
    • Dall'Asta, C., Vedani, P., Manunta, P., Pizzocri, P., Marchi, M., Paganelli, M., Folli, F. and Pontiroli, A. E. (2009) Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity. Nutr. Metab. Cardiovasc. Dis. 19, 110-114
    • (2009) Nutr. Metab. Cardiovasc. Dis. , vol.19 , pp. 110-114
    • Dall'Asta, C.1    Vedani, P.2    Manunta, P.3    Pizzocri, P.4    Marchi, M.5    Paganelli, M.6    Folli, F.7    Pontiroli, A.E.8
  • 20
    • 0029977757 scopus 로고    scopus 로고
    • Obesity/insulin resistance is associated with endothelial dysfunction.Implications for the syndrome of insulin resistance.
    • Steinberg, H. O., Chaker, H., Leaming, R., Johnson, A., Brechtel, G. and Baron, A. D. (1996) Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J. Clin. Invest. 97, 2601-2610
    • (1996) J. Clin. Invest. , vol.97 , pp. 2601-2610
    • Steinberg, H.O.1    Chaker, H.2    Leaming, R.3    Johnson, A.4    Brechtel, G.5    Baron, A.D.6
  • 22
    • 84883790321 scopus 로고    scopus 로고
    • Flow-mediated dilation and cardiovascular risk prediction: a systematic review with meta-analysis
    • doi:10.1016/j.ijcard.2012.09.047
    • Ras, R. T., Streppel, M. T., Draijer, R. and Zock, P. L. (2012) Flow-mediated dilation and cardiovascular risk prediction: a systematic review with meta-analysis. Int. J. Cardiol., doi:10.1016/j.ijcard.2012.09.047
    • (2012) Int. J. Cardiol.
    • Ras, R.T.1    Streppel, M.T.2    Draijer, R.3    Zock, P.L.4
  • 23
    • 84055184240 scopus 로고    scopus 로고
    • Endothelial function
    • Vita, J. A. (2011) Endothelial function. Circulation 124, e906-e912
    • (2011) Circulation , vol.124
    • Vita, J.A.1
  • 24
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress
    • Cai, H. and Harrison, D. G. (2000) Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res. 87, 840-844
    • (2000) Circ. Res. , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 25
    • 24144498067 scopus 로고    scopus 로고
    • Mechanisms of endothelial dysfunction in obesity
    • Avogaro, A. and de Kreutzenberg, S. V. (2005) Mechanisms of endothelial dysfunction in obesity. Clin. Chim. Acta 360, 9-26
    • (2005) Clin. Chim. Acta , vol.360 , pp. 9-26
    • Avogaro, A.1    de Kreutzenberg, S.V.2
  • 26
    • 2442490850 scopus 로고    scopus 로고
    • Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone
    • Keidar, S., Kaplan, M., Pavlotzky, E., Coleman, R., Hayek, T., Hamoud, S. and Aviram, M. (2004) Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone. Circulation 109, 2213-2220
    • (2004) Circulation , vol.109 , pp. 2213-2220
    • Keidar, S.1    Kaplan, M.2    Pavlotzky, E.3    Coleman, R.4    Hayek, T.5    Hamoud, S.6    Aviram, M.7
  • 27
    • 0037035471 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonism in experimental atherosclerosis
    • Rajagopalan, S., Duquaine, D., King, S., Pitt, B. and Patel, P. (2002) Mineralocorticoid receptor antagonism in experimental atherosclerosis. Circulation 105, 2212-2216
    • (2002) Circulation , vol.105 , pp. 2212-2216
    • Rajagopalan, S.1    Duaine, D.2    King, S.3    Pitt, B.4    Patel, P.5
  • 28
    • 33646488692 scopus 로고    scopus 로고
    • Aldosterone antagonism improves endothelial-dependent vasorelaxation in heart failure via upregulation of endothelial nitric oxide synthase production
    • Thai, H. M., Do, B. Q., Tran, T. D., Gaballa, M. A. and Goldman, S. (2006) Aldosterone antagonism improves endothelial-dependent vasorelaxation in heart failure via upregulation of endothelial nitric oxide synthase production. J. Card. Fail. 12, 240-245
    • (2006) J. Card. Fail. , vol.12 , pp. 240-245
    • Thai, H.M.1    Do, B.Q.2    Tran, T.D.3    Gaballa, M.A.4    Goldman, S.5
  • 29
    • 35848946585 scopus 로고    scopus 로고
    • Mineralocorticoid receptor blockade improves vasomotor dysfunction and vascular oxidative stress early after myocardial infarction
    • Sartorio, C. L., Fraccarollo, D., Galuppo, P., Leutke, M., Ertl, G., Stefanon, I. and Bauersachs, J. (2007) Mineralocorticoid receptor blockade improves vasomotor dysfunction and vascular oxidative stress early after myocardial infarction. Hypertension 50, 919-925
    • (2007) Hypertension , vol.50 , pp. 919-925
    • Sartorio, C.L.1    Fraccarollo, D.2    Galuppo, P.3    Leutke, M.4    Ertl, G.5    Stefanon, I.6    Bauersachs, J.7
  • 30
    • 0034651798 scopus 로고    scopus 로고
    • Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure
    • Farquharson, C. A. and Struthers, A. D. (2000) Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation 101, 594-597
    • (2000) Circulation , vol.101 , pp. 594-597
    • Farquharson, C.A.1    Struthers, A.D.2
  • 31
    • 2942604308 scopus 로고    scopus 로고
    • Effect of spironolactone on endothelial function in patients with congestive heart failure on conventional medical therapy
    • Abiose, A. K., Mansoor, G. A., Barry, M., Soucier, R., Nair, C. K. and Hager, D. (2004) Effect of spironolactone on endothelial function in patients with congestive heart failure on conventional medical therapy. Am. J. Cardiol. 93, 1564-1566
    • (2004) Am. J. Cardiol. , vol.93 , pp. 1564-1566
    • Abiose, A.K.1    Mansoor, G.A.2    Barry, M.3    Soucier, R.4    Nair, C.K.5    Hager, D.6
  • 33
    • 2642544579 scopus 로고    scopus 로고
    • Erratum
    • Erratum (2002) J. Am. Coll. Cardiol. 39, 1082
    • (2002) J. Am. Coll. Cardiol. , vol.39 , pp. 1082
  • 37
    • 33846862034 scopus 로고    scopus 로고
    • Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47phox expression and evidence of endothelial oxidative stress
    • Silver, A., Beske, S. D., Christou, D. D., Donato, A. J., Moreau, K. L., Eskurza, I., Gates, P. E. and Seals, D. R. (2007) Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47phox expression and evidence of endothelial oxidative stress. Circulation 115, 627-637
    • (2007) Circulation , vol.115 , pp. 627-637
    • Silver, A.1    Beske, S.D.2    Christou, D.D.3    Donato, A.J.4    Moreau, K.L.5    Eskurza, I.6    Gates, P.E.7    Seals, D.R.8
  • 40
    • 34347251604 scopus 로고    scopus 로고
    • Quantification of F2-isoprostanes as a biomarker of oxidative stress
    • Milne, G. L., Sanchez, S. C., Musiek, E. S. and Morrow, J. D. (2007) Quantification of F2-isoprostanes as a biomarker of oxidative stress. Nat. Protoc. 2, 221-226
    • (2007) Nat. Protoc. , vol.2 , pp. 221-226
    • Milne, G.L.1    Sanchez, S.C.2    Musiek, E.S.3    Morrow, J.D.4
  • 41
    • 17644393220 scopus 로고    scopus 로고
    • Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men
    • Christou, D. D., Gentile, C. L., DeSouza, C. A., Seals, D. R. and Gates, P. E. (2005) Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men. Circulation 111, 1904-1914
    • (2005) Circulation , vol.111 , pp. 1904-1914
    • Christou, D.D.1    Gentile, C.L.2    DeSouza, C.A.3    Seals, D.R.4    Gates, P.E.5
  • 43
    • 69749100645 scopus 로고    scopus 로고
    • Predictors of hyperkalemia risk following hypertension control with aldosterone blockade
    • Khosla, N., Kalaitzidis, R. and Bakris, G. L. (2009) Predictors of hyperkalemia risk following hypertension control with aldosterone blockade. Am. J. Nephrol. 30, 418-424
    • (2009) Am. J. Nephrol. , vol.30 , pp. 418-424
    • Khosla, N.1    Kalaitzidis, R.2    Bakris, G.L.3
  • 44
    • 73849140879 scopus 로고    scopus 로고
    • Efficacy of spironolactone therapy in patients with true resistant hypertension
    • de Souza, F., Muxfeldt, E., Fiszman, R. and Salles, G. (2010) Efficacy of spironolactone therapy in patients with true resistant hypertension. Hypertension 55, 147-152
    • (2010) Hypertension , vol.55 , pp. 147-152
    • de Souza, F.1    Muxfeldt, E.2    Fiszman, R.3    Salles, G.4
  • 45
    • 84873027749 scopus 로고    scopus 로고
    • Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease?
    • Bender, S. B., McGraw, A. P., Jaffe, I. Z. and Sowers, J. R. (2013) Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease?. Diabetes 62, 313-319
    • (2013) Diabetes , vol.62 , pp. 313-319
    • Bender, S.B.1    McGraw, A.P.2    Jaffe, I.Z.3    Sowers, J.R.4
  • 46
    • 77649327873 scopus 로고    scopus 로고
    • Aldosterone and mineralocorticoid receptors in the cardiovascular system
    • Funder, J. W. (2010) Aldosterone and mineralocorticoid receptors in the cardiovascular system. Prog. Cardiovasc. Dis. 52, 393-400
    • (2010) Prog. Cardiovasc. Dis. , vol.52 , pp. 393-400
    • Funder, J.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.