Divergent synthesis of 4-epi-fagomine, 3,4-dihydroxypipecolic acid, and a dihydroxyindolizidine and their β-galactosidase inhibitory and immunomodulatory activities

Journal of Organic Chemistry

Volumn 78, Issue 15, 2013, Pages 7406-7413

  Kumar, K S Ajish ^a   Rathee, J S ^a   Subramanian, M ^a   Chattopadhyay, S ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC SYNTHESIS; CARBONYL PROTECTION; DIVERGENT SYNTHESIS; IMMUNOMODULATORY ACTIVITIES; PROINFLAMMATORY CYTOKINES; RAW 264.7 MACROPHAGES; REDUCTIVE AMINATION; STAUDINGER REACTIONS;

ADDITION REACTIONS; ALKALOIDS; ENZYME ACTIVITY; OZONE;

ENZYME INHIBITION;

3,4 DIHYDROXYPIPECOLIC ACID; 4 EPIFAGOMINE; BETA GALACTOSIDASE; CARBONYL DERIVATIVE; CYTOKINE; DIHYDROXYINDOLIZIDINE; HYDROXYL GROUP; IMMUNOMODULATING AGENT; INTERLEUKIN 1BETA; LENTIGINOSINE; LIPOPOLYSACCHARIDE; PLANT MEDICINAL PRODUCT; SWAINSONINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINATION; ANIMAL CELL; ARTICLE; ASYMMETRIC SYNTHESIS; BIOTRANSFORMATION; CHIRALITY; CONTROLLED STUDY; DRUG TARGETING; ENZYME INHIBITION; IMMUNOMODULATION; MACROPHAGE; MEDIATOR; NONHUMAN; ONE POT SYNTHESIS; OZONOLYSIS; PROTEIN BLOOD LEVEL; STAUDINGER REACTION;

EID: 84881230343     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo400448p     Document Type: Article

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