Hexavalent chromium Cr(VI) up-regulates COX-2 expression through an NFκB/c-Jun/AP-1-dependent pathway

Environmental Health Perspectives

Volumn 120, Issue 4, 2012, Pages 547-553

  Zuo, Zhenghong ^a,b   Cai, Tongjian ^a   Li, Jingxia ^a   Zhang, Dongyun ^a   Yu, Yonghui ^a   Huang, Chuanshu ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b XIAMEN UNIVERSITY   (China)

Author keywords

AP 1; c Jun; Chromium; COX 2; NF B

Indexed keywords

CHROMIUM; CYCLOOXYGENASE 2; I KAPPA B ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN C FOS; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR FRA 1; TRANSCRIPTION FACTOR JUNB; TRANSCRIPTION FACTOR JUND; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CLONOGENIC ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA BINDING; EPITHELIUM CELL; FIBROBLAST; GEL MOBILITY SHIFT ASSAY; GENE SILENCING; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CARCINOGENS; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; CHROMIUM; COLONY-FORMING UNITS ASSAY; CYCLOOXYGENASE 2; ELECTROPHORESIS; FIBROBLASTS; MICE; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-JUN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; UP-REGULATION;

EID: 84859357647     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1104179     Document Type: Article

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