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Volumn 8, Issue 8, 2013, Pages

Slx8 Removes Pli1-Dependent Protein-SUMO Conjugates Including SUMOylated Topoisomerase I to Promote Genome Stability

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; LIGASE; SUMO DEPENDENT UBIQUITIN LIGASE SLX8; SUMO LIGASE PLI1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

EID: 84881187206     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071960     Document Type: Article
Times cited : (14)

References (66)
  • 1
    • 68249093137 scopus 로고    scopus 로고
    • Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks
    • Schleker T, Nagai S, Gasser SM, (2009) Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks. DNA Repair (Amst) 8: 1089-1100.
    • (2009) DNA Repair (Amst) , vol.8 , pp. 1089-1100
    • Schleker, T.1    Nagai, S.2    Gasser, S.M.3
  • 2
    • 29244473887 scopus 로고    scopus 로고
    • SUMO keeps a check on recombination during DNA replication
    • Ulrich HD, Vogel S, Davies AA, (2005) SUMO keeps a check on recombination during DNA replication. Cell Cycle 4: 1699-1702.
    • (2005) Cell Cycle , vol.4 , pp. 1699-1702
    • Ulrich, H.D.1    Vogel, S.2    Davies, A.A.3
  • 3
    • 84876886904 scopus 로고    scopus 로고
    • Regulation of DNA damage responses by ubiquitin and SUMO
    • Jackson SP, Durocher D, (2013) Regulation of DNA damage responses by ubiquitin and SUMO. Mol Cell 49: 795-807.
    • (2013) Mol Cell , vol.49 , pp. 795-807
    • Jackson, S.P.1    Durocher, D.2
  • 4
    • 4444301185 scopus 로고    scopus 로고
    • SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?
    • Gill G, (2004) SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? Genes Dev 18: 2046-2059.
    • (2004) Genes Dev , vol.18 , pp. 2046-2059
    • Gill, G.1
  • 5
    • 0037086643 scopus 로고    scopus 로고
    • Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover
    • Hardeland U, Steinacher R, Jiricny J, Schär P, (2002) Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover. EMBO J 21: 1456-1464.
    • (2002) EMBO J , vol.21 , pp. 1456-1464
    • Hardeland, U.1    Steinacher, R.2    Jiricny, J.3    Schär, P.4
  • 6
    • 84979831265 scopus 로고    scopus 로고
    • Regulatory Functions of Ubiquitin and SUMO in DNA Repair Pathways
    • Jentsch S, Müller S, (2010) Regulatory Functions of Ubiquitin and SUMO in DNA Repair Pathways. Subcell Biochem 54: 184-194.
    • (2010) Subcell Biochem , vol.54 , pp. 184-194
    • Jentsch, S.1    Müller, S.2
  • 7
    • 17144410054 scopus 로고    scopus 로고
    • Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation
    • Steinacher R, Schär P, (2005) Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation. Curr Biol 15: 616-623.
    • (2005) Curr Biol , vol.15 , pp. 616-623
    • Steinacher, R.1    Schär, P.2
  • 8
    • 34547113757 scopus 로고    scopus 로고
    • Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation
    • Wei F, Schöler HR, Atchison ML, (2007) Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation. J Biol Chem 282: 21551-21560.
    • (2007) J Biol Chem , vol.282 , pp. 21551-21560
    • Wei, F.1    Schöler, H.R.2    Atchison, M.L.3
  • 9
    • 77958550713 scopus 로고    scopus 로고
    • Ubiquitin/SUMO modification regulates VHL protein stability and nucleocytoplasmic localization
    • Cai Q, Robertson ES, (2010) Ubiquitin/SUMO modification regulates VHL protein stability and nucleocytoplasmic localization. PLoS One 5.
    • (2010) PLoS One , vol.5
    • Cai, Q.1    Robertson, E.S.2
  • 10
    • 63649144413 scopus 로고    scopus 로고
    • Principles of ubiquitin and SUMO modifications in DNA repair
    • Bergink S, Jentsch S, (2009) Principles of ubiquitin and SUMO modifications in DNA repair. Nature 458: 461-467.
    • (2009) Nature , vol.458 , pp. 461-467
    • Bergink, S.1    Jentsch, S.2
  • 11
    • 37749023742 scopus 로고    scopus 로고
    • The role of Schizosaccharomyces pombe SUMO ligases in genome stability
    • Watts FZ, Skilton A, Ho JC, Boyd LK, Trickey MA, et al. (2007) The role of Schizosaccharomyces pombe SUMO ligases in genome stability. Biochem Soc Trans 35: 1379-1384.
    • (2007) Biochem Soc Trans , vol.35 , pp. 1379-1384
    • Watts, F.Z.1    Skilton, A.2    Ho, J.C.3    Boyd, L.K.4    Trickey, M.A.5
  • 14
    • 11144324990 scopus 로고    scopus 로고
    • Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage
    • Andrews EA, Palecek J, Sergeant J, Taylor E, Lehmann AR, et al. (2005) Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage. Mol Cell Biol 25: 185-196.
    • (2005) Mol Cell Biol , vol.25 , pp. 185-196
    • Andrews, E.A.1    Palecek, J.2    Sergeant, J.3    Taylor, E.4    Lehmann, A.R.5
  • 15
    • 68049103216 scopus 로고    scopus 로고
    • An additional role for SUMO in ubiquitin-mediated proteolysis
    • Geoffroy MC, Hay RT, (2009) An additional role for SUMO in ubiquitin-mediated proteolysis. Nat Rev Mol Cell Biol 10: 564-568.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 564-568
    • Geoffroy, M.C.1    Hay, R.T.2
  • 16
    • 62749091677 scopus 로고    scopus 로고
    • Crosstalk between the SUMO and ubiquitin pathways
    • Hunter T, Sun H, (2008) Crosstalk between the SUMO and ubiquitin pathways. Ernst Schering Found Symp Proc pp. 1-16.
    • (2008) Ernst Schering Found Symp Proc , pp. 1-16
    • Hunter, T.1    Sun, H.2
  • 17
    • 37249076354 scopus 로고    scopus 로고
    • The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity
    • Ii T, Fung J, Mullen JR, Brill SJ, (2007) The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity. Cell Cycle 6: 2800-2809.
    • (2007) Cell Cycle , vol.6 , pp. 2800-2809
    • Ii, T.1    Fung, J.2    Mullen, J.R.3    Brill, S.J.4
  • 18
    • 50649104647 scopus 로고    scopus 로고
    • Activation of the Slx5-Slx8 ubiquitin ligase by poly-small ubiquitin-like modifier conjugates
    • Mullen JR, Brill SJ, (2008) Activation of the Slx5-Slx8 ubiquitin ligase by poly-small ubiquitin-like modifier conjugates. J Biol Chem 283: 19912-19921.
    • (2008) J Biol Chem , vol.283 , pp. 19912-19921
    • Mullen, J.R.1    Brill, S.J.2
  • 20
    • 36348964395 scopus 로고    scopus 로고
    • The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation
    • Xie Y, Kerscher O, Kroetz MB, McConchie HF, Sung P, et al. (2007) The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation. J Biol Chem 282: 34176-34184.
    • (2007) J Biol Chem , vol.282 , pp. 34176-34184
    • Xie, Y.1    Kerscher, O.2    Kroetz, M.B.3    McConchie, H.F.4    Sung, P.5
  • 21
    • 34648816891 scopus 로고    scopus 로고
    • Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins
    • Sun H, Leverson JD, Hunter T, (2007) Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins. EMBO J 26: 4102-4112.
    • (2007) EMBO J , vol.26 , pp. 4102-4112
    • Sun, H.1    Leverson, J.D.2    Hunter, T.3
  • 22
    • 34548213631 scopus 로고    scopus 로고
    • The Slx5-Slx8 complex affects sumoylation of DNA repair proteins and negatively regulates recombination
    • Burgess RC, Rahman S, Lisby M, Rothstein R, Zhao X, (2007) The Slx5-Slx8 complex affects sumoylation of DNA repair proteins and negatively regulates recombination. Mol Cell Biol 27: 6153-6162.
    • (2007) Mol Cell Biol , vol.27 , pp. 6153-6162
    • Burgess, R.C.1    Rahman, S.2    Lisby, M.3    Rothstein, R.4    Zhao, X.5
  • 23
    • 79953761297 scopus 로고    scopus 로고
    • SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability
    • Heideker J, Prudden J, Perry JJ, Tainer JA, Boddy MN, (2011) SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability. PLoS Genet 7: e1001320.
    • (2011) PLoS Genet , vol.7
    • Heideker, J.1    Prudden, J.2    Perry, J.J.3    Tainer, J.A.4    Boddy, M.N.5
  • 24
    • 0034923502 scopus 로고    scopus 로고
    • DNA topoisomerases: structure, function, and mechanism
    • Champoux JJ, (2001) DNA topoisomerases: structure, function, and mechanism. Annu Rev Biochem 70: 369-413.
    • (2001) Annu Rev Biochem , vol.70 , pp. 369-413
    • Champoux, J.J.1
  • 25
    • 0025133118 scopus 로고
    • Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons
    • D'Arpa P, Beardmore C, Liu LF, (1990) Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. Cancer Res 50: 6919-6924.
    • (1990) Cancer Res , vol.50 , pp. 6919-6924
    • D'Arpa, P.1    Beardmore, C.2    Liu, L.F.3
  • 26
    • 0027173884 scopus 로고
    • Hypersensitivity of Cockayne's syndrome cells to camptothecin is associated with the generation of abnormally high levels of double strand breaks in nascent DNA
    • Squires S, Ryan AJ, Strutt HL, Johnson RT, (1993) Hypersensitivity of Cockayne's syndrome cells to camptothecin is associated with the generation of abnormally high levels of double strand breaks in nascent DNA. Cancer Res 53: 2012-2019.
    • (1993) Cancer Res , vol.53 , pp. 2012-2019
    • Squires, S.1    Ryan, A.J.2    Strutt, H.L.3    Johnson, R.T.4
  • 27
    • 0035029153 scopus 로고    scopus 로고
    • Tumor cell death induced by topoisomerase-targeting drugs
    • Li TK, Liu LF, (2001) Tumor cell death induced by topoisomerase-targeting drugs. Annu Rev Pharmacol Toxicol 41: 53-77.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 53-77
    • Li, T.K.1    Liu, L.F.2
  • 28
    • 79958072366 scopus 로고    scopus 로고
    • DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes
    • Prudden J, Perry JJ, Nie M, Vashisht AA, Arvai AS, et al. (2011) DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes. Mol Cell Biol 31: 2299-2310.
    • (2011) Mol Cell Biol , vol.31 , pp. 2299-2310
    • Prudden, J.1    Perry, J.J.2    Nie, M.3    Vashisht, A.A.4    Arvai, A.S.5
  • 29
    • 35048872745 scopus 로고    scopus 로고
    • Topoisomerase I-dependent viability loss in Saccharomyces cerevisiae mutants defective in both SUMO conjugation and DNA repair
    • Chen XL, Silver HR, Xiong L, Belichenko I, Adegite C, et al. (2007) Topoisomerase I-dependent viability loss in Saccharomyces cerevisiae mutants defective in both SUMO conjugation and DNA repair. Genetics 177: 17-30.
    • (2007) Genetics , vol.177 , pp. 17-30
    • Chen, X.L.1    Silver, H.R.2    Xiong, L.3    Belichenko, I.4    Adegite, C.5
  • 30
    • 21244440716 scopus 로고    scopus 로고
    • Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast
    • Ahn JS, Osman F, Whitby MC, (2005) Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast. EMBO J 24: 2011-2023.
    • (2005) EMBO J , vol.24 , pp. 2011-2023
    • Ahn, J.S.1    Osman, F.2    Whitby, M.C.3
  • 31
    • 77955479780 scopus 로고    scopus 로고
    • Homologous recombination restarts blocked replication forks at the expense of genome rearrangements by template exchange
    • Lambert S, Mizuno K, Blaisonneau J, Martineau S, Chanet R, et al. (2010) Homologous recombination restarts blocked replication forks at the expense of genome rearrangements by template exchange. Mol Cell 39: 346-359.
    • (2010) Mol Cell , vol.39 , pp. 346-359
    • Lambert, S.1    Mizuno, K.2    Blaisonneau, J.3    Martineau, S.4    Chanet, R.5
  • 32
    • 20444424939 scopus 로고    scopus 로고
    • Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier
    • Lambert S, Watson A, Sheedy DM, Martin B, Carr AM, (2005) Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier. Cell 121: 689-702.
    • (2005) Cell , vol.121 , pp. 689-702
    • Lambert, S.1    Watson, A.2    Sheedy, D.M.3    Martin, B.4    Carr, A.M.5
  • 33
    • 72849150228 scopus 로고    scopus 로고
    • Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism
    • Mizuno K, Lambert S, Baldacci G, Murray JM, Carr AM, (2009) Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism. Genes Dev 23: 2876-2886.
    • (2009) Genes Dev , vol.23 , pp. 2876-2886
    • Mizuno, K.1    Lambert, S.2    Baldacci, G.3    Murray, J.M.4    Carr, A.M.5
  • 34
    • 84872138637 scopus 로고    scopus 로고
    • Recombination-restarted replication makes inverted chromosome fusions at inverted repeats
    • Mizuno K, Miyabe I, Schalbetter SA, Carr AM, Murray JM, (2013) Recombination-restarted replication makes inverted chromosome fusions at inverted repeats. Nature 493: 246-249.
    • (2013) Nature , vol.493 , pp. 246-249
    • Mizuno, K.1    Miyabe, I.2    Schalbetter, S.A.3    Carr, A.M.4    Murray, J.M.5
  • 35
    • 0031818471 scopus 로고    scopus 로고
    • Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe
    • Bähler J, Wu JQ, Longtine MS, Shah NG, McKenzie A 3rd, et al. (1998) Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast 14: 943-951.
    • (1998) Yeast , vol.14 , pp. 943-951
    • Bähler, J.1    Wu, J.Q.2    Longtine, M.S.3    Shah, N.G.4    McKenzie 3rd, A.5
  • 36
    • 0026025891 scopus 로고
    • Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
    • Moreno S, Klar A, Nurse P, (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 194: 795-823.
    • (1991) Methods Enzymol , vol.194 , pp. 795-823
    • Moreno, S.1    Klar, A.2    Nurse, P.3
  • 37
    • 68349158055 scopus 로고    scopus 로고
    • Monitoring homologous recombination following replication fork perturbation in the fission yeast Schizosaccharomyces pombe
    • Osman F, Whitby MC, (2009) Monitoring homologous recombination following replication fork perturbation in the fission yeast Schizosaccharomyces pombe. Methods Mol Biol 521: 535-552.
    • (2009) Methods Mol Biol , vol.521 , pp. 535-552
    • Osman, F.1    Whitby, M.C.2
  • 38
    • 53149087431 scopus 로고    scopus 로고
    • The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair
    • Sun W, Nandi S, Osman F, Ahn JS, Jakovleska J, et al. (2008) The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair. Mol Cell 32: 118-128.
    • (2008) Mol Cell , vol.32 , pp. 118-128
    • Sun, W.1    Nandi, S.2    Osman, F.3    Ahn, J.S.4    Jakovleska, J.5
  • 40
    • 84858330322 scopus 로고    scopus 로고
    • The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability
    • Steinacher R, Osman F, Dalgaard JZ, Lorenz A, Whitby MC, (2012) The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability. Genes Dev 26: 594-602.
    • (2012) Genes Dev , vol.26 , pp. 594-602
    • Steinacher, R.1    Osman, F.2    Dalgaard, J.Z.3    Lorenz, A.4    Whitby, M.C.5
  • 41
    • 79959381925 scopus 로고    scopus 로고
    • Comparative proteomic analysis identifies a role for SUMO in protein quality control
    • Tatham MH, Matic I, Mann M, Hay RT, (2011) Comparative proteomic analysis identifies a role for SUMO in protein quality control. Sci Signal 4: rs4.
    • (2011) Sci Signal , vol.4
    • Tatham, M.H.1    Matic, I.2    Mann, M.3    Hay, R.T.4
  • 42
    • 67649173012 scopus 로고    scopus 로고
    • System-wide changes to SUMO modifications in response to heat shock
    • Golebiowski F, Matic I, Tatham MH, Cole C, Yin Y, et al. (2009) System-wide changes to SUMO modifications in response to heat shock. Sci Signal 2: ra24.
    • (2009) Sci Signal , vol.2
    • Golebiowski, F.1    Matic, I.2    Tatham, M.H.3    Cole, C.4    Yin, Y.5
  • 43
    • 6344254386 scopus 로고    scopus 로고
    • Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance
    • Xhemalce B, Seeler JS, Thon G, Dejean A, Arcangioli B, (2004) Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance. EMBO J 23: 3844-3853.
    • (2004) EMBO J , vol.23 , pp. 3844-3853
    • Xhemalce, B.1    Seeler, J.S.2    Thon, G.3    Dejean, A.4    Arcangioli, B.5
  • 44
    • 34447563946 scopus 로고    scopus 로고
    • Rad3-dependent phosphorylation of the checkpoint clamp regulates repair-pathway choice
    • Kai M, Furuya K, Paderi F, Carr AM, Wang TS, (2007) Rad3-dependent phosphorylation of the checkpoint clamp regulates repair-pathway choice. Nat Cell Biol 9: 691-697.
    • (2007) Nat Cell Biol , vol.9 , pp. 691-697
    • Kai, M.1    Furuya, K.2    Paderi, F.3    Carr, A.M.4    Wang, T.S.5
  • 45
    • 68849127270 scopus 로고    scopus 로고
    • Fbh1 limits Rad51-dependent recombination at blocked replication forks
    • Lorenz A, Osman F, Folkyte V, Sofueva S, Whitby MC, (2009) Fbh1 limits Rad51-dependent recombination at blocked replication forks. Mol Cell Biol 29: 4742-4756.
    • (2009) Mol Cell Biol , vol.29 , pp. 4742-4756
    • Lorenz, A.1    Osman, F.2    Folkyte, V.3    Sofueva, S.4    Whitby, M.C.5
  • 46
    • 9144239301 scopus 로고    scopus 로고
    • DNA repair by a Rad22-Mus81-dependent pathway that is independent of Rhp51
    • Doe CL, Osman F, Dixon J, Whitby MC, (2004) DNA repair by a Rad22-Mus81-dependent pathway that is independent of Rhp51. Nucleic Acids Res 32: 5570-5581.
    • (2004) Nucleic Acids Res , vol.32 , pp. 5570-5581
    • Doe, C.L.1    Osman, F.2    Dixon, J.3    Whitby, M.C.4
  • 47
    • 66049151307 scopus 로고    scopus 로고
    • Schizosaccharomyces pombe Rtf2 mediates site-specific replication termination by inhibiting replication restart
    • Inagawa T, Yamada-Inagawa T, Eydmann T, Mian IS, Wang TS, et al. (2009) Schizosaccharomyces pombe Rtf2 mediates site-specific replication termination by inhibiting replication restart. Proc Natl Acad Sci U S A 106: 7927-7932.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 7927-7932
    • Inagawa, T.1    Yamada-Inagawa, T.2    Eydmann, T.3    Mian, I.S.4    Wang, T.S.5
  • 48
    • 4744360999 scopus 로고    scopus 로고
    • A proteome-wide approach identifies sumoylated substrate proteins in yeast
    • Panse VG, Hardeland U, Werner T, Kuster B, Hurt E, (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279: 41346-41351.
    • (2004) J Biol Chem , vol.279 , pp. 41346-41351
    • Panse, V.G.1    Hardeland, U.2    Werner, T.3    Kuster, B.4    Hurt, E.5
  • 50
    • 34249942213 scopus 로고    scopus 로고
    • Exploring the roles of Mus81-Eme1/Mms4 at perturbed replication forks
    • Osman F, Whitby MC, (2007) Exploring the roles of Mus81-Eme1/Mms4 at perturbed replication forks. DNA Repair (Amst) 6: 1004-1017.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 1004-1017
    • Osman, F.1    Whitby, M.C.2
  • 51
    • 43249128930 scopus 로고    scopus 로고
    • Mus81 is essential for sister chromatid recombination at broken replication forks
    • Roseaulin L, Yamada Y, Tsutsui Y, Russell P, Iwasaki H, et al. (2008) Mus81 is essential for sister chromatid recombination at broken replication forks. EMBO J 27: 1378-1387.
    • (2008) EMBO J , vol.27 , pp. 1378-1387
    • Roseaulin, L.1    Yamada, Y.2    Tsutsui, Y.3    Russell, P.4    Iwasaki, H.5
  • 52
    • 84862908473 scopus 로고    scopus 로고
    • Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes
    • Regairaz M, Zhang YW, Fu H, Agama KK, Tata N, et al. (2011) Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes. J Cell Biol 195: 739-749.
    • (2011) J Cell Biol , vol.195 , pp. 739-749
    • Regairaz, M.1    Zhang, Y.W.2    Fu, H.3    Agama, K.K.4    Tata, N.5
  • 53
    • 0035422206 scopus 로고    scopus 로고
    • Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells
    • Desai SD, Li TK, Rodriguez-Bauman A, Rubin EH, Liu LF, (2001) Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells. Cancer Res 61: 5926-5932.
    • (2001) Cancer Res , vol.61 , pp. 5926-5932
    • Desai, S.D.1    Li, T.K.2    Rodriguez-Bauman, A.3    Rubin, E.H.4    Liu, L.F.5
  • 54
    • 0030854371 scopus 로고    scopus 로고
    • Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin
    • Desai SD, Liu LF, Vazquez-Abad D, D'Arpa P, (1997) Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin. J Biol Chem 272: 24159-24164.
    • (1997) J Biol Chem , vol.272 , pp. 24159-24164
    • Desai, S.D.1    Liu, L.F.2    Vazquez-Abad, D.3    D'Arpa, P.4
  • 55
    • 0037079237 scopus 로고    scopus 로고
    • SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin
    • Horie K, Tomida A, Sugimoto Y, Yasugi T, Yoshikawa H, et al. (2002) SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin. Oncogene 21: 7913-7922.
    • (2002) Oncogene , vol.21 , pp. 7913-7922
    • Horie, K.1    Tomida, A.2    Sugimoto, Y.3    Yasugi, T.4    Yoshikawa, H.5
  • 56
    • 0034635958 scopus 로고    scopus 로고
    • SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage
    • Mao Y, Sun M, Desai SD, Liu LF, (2000) SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage. Proc Natl Acad Sci U S A 97: 4046-4051.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 4046-4051
    • Mao, Y.1    Sun, M.2    Desai, S.D.3    Liu, L.F.4
  • 57
    • 51049099613 scopus 로고    scopus 로고
    • A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes
    • Lin CP, Ban Y, Lyu YL, Desai SD, Liu LF, (2008) A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes. J Biol Chem 283: 21074-21083.
    • (2008) J Biol Chem , vol.283 , pp. 21074-21083
    • Lin, C.P.1    Ban, Y.2    Lyu, Y.L.3    Desai, S.D.4    Liu, L.F.5
  • 59
    • 84875220657 scopus 로고    scopus 로고
    • Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition
    • Berti M, Chaudhuri AR, Thangavel S, Gomathinayagam S, Kenig S, et al. (2013) Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat Struct Mol Biol 20: 347-354.
    • (2013) Nat Struct Mol Biol , vol.20 , pp. 347-354
    • Berti, M.1    Chaudhuri, A.R.2    Thangavel, S.3    Gomathinayagam, S.4    Kenig, S.5
  • 60
    • 55249096736 scopus 로고    scopus 로고
    • The fast-growing business of SUMO chains
    • Ulrich HD, (2008) The fast-growing business of SUMO chains. Mol Cell 32: 301-305.
    • (2008) Mol Cell , vol.32 , pp. 301-305
    • Ulrich, H.D.1
  • 61
    • 33750437743 scopus 로고    scopus 로고
    • Ubc9- and Mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks
    • Branzei D, Sollier J, Liberi G, Zhao X, Maeda D, et al. (2006) Ubc9- and Mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell 127: 509-522.
    • (2006) Cell , vol.127 , pp. 509-522
    • Branzei, D.1    Sollier, J.2    Liberi, G.3    Zhao, X.4    Maeda, D.5
  • 62
    • 84861765707 scopus 로고    scopus 로고
    • RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair
    • Galanty Y, Belotserkovskaya R, Coates J, Jackson SP, (2012) RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair. Genes Dev 26: 1179-1195.
    • (2012) Genes Dev , vol.26 , pp. 1179-1195
    • Galanty, Y.1    Belotserkovskaya, R.2    Coates, J.3    Jackson, S.P.4
  • 63
    • 84875219980 scopus 로고    scopus 로고
    • Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis
    • Burkovics P, Sebesta M, Sisakova A, Plault N, Szukacsov V, et al. (2013) Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis. EMBO J 32: 742-755.
    • (2013) EMBO J , vol.32 , pp. 742-755
    • Burkovics, P.1    Sebesta, M.2    Sisakova, A.3    Plault, N.4    Szukacsov, V.5
  • 64
    • 22944474665 scopus 로고    scopus 로고
    • SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase
    • Pfander B, Moldovan GL, Sacher M, Hoege C, Jentsch S, (2005) SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase. Nature 436: 428-433.
    • (2005) Nature , vol.436 , pp. 428-433
    • Pfander, B.1    Moldovan, G.L.2    Sacher, M.3    Hoege, C.4    Jentsch, S.5
  • 65
    • 21244449061 scopus 로고    scopus 로고
    • Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p
    • Papouli E, Chen S, Davies AA, Huttner D, Krejci L, et al. (2005) Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p. Mol Cell 19: 123-133.
    • (2005) Mol Cell , vol.19 , pp. 123-133
    • Papouli, E.1    Chen, S.2    Davies, A.A.3    Huttner, D.4    Krejci, L.5
  • 66
    • 0037925515 scopus 로고    scopus 로고
    • Complex mechanism of site-specific DNA replication termination in fission yeast
    • Codlin S, Dalgaard JZ, (2003) Complex mechanism of site-specific DNA replication termination in fission yeast. EMBO J 22: 3431-3440.
    • (2003) EMBO J , vol.22 , pp. 3431-3440
    • Codlin, S.1    Dalgaard, J.Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.