Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis

EMBO Journal

Volumn 32, Issue 5, 2013, Pages 742-755

  Burkovics, Peter ^a,b   Sebesta, Marek ^a   Sisakova, Alexandra ^a   Plault, Nicolas ^c   Szukacsov, Valeria ^b   Robert, Thomas ^c,f   Pinter, Lajos ^b   Marini, Victoria ^a   Kolesar, Peter ^a   Haracska, Lajos ^b   Gangloff, Serge ^c,d,g   Krejci, Lumir ^a,e  

^a MASARYK UNIVERSITY   (Czech Republic)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^d CNRS   (France)

^e ST ANNE S UNIVERSITY HOSPITAL   (Czech Republic)

^f INSTITUTE OF HUMAN GENETICS   (France)

^g INSTITUT PASTEUR   (France)

Author keywords

DNA repair synthesis; genome stability; PCNA SUMOylation; Srs2; SUMO interacting motif

Indexed keywords

CARRIER PROTEIN; CYCLINE; DEOXYRIBONUCLEOPROTEIN; RAD51 PROTEIN; SRS2 PROTEIN; SUMO PROTEIN; UNCLASSIFIED DRUG;

CARBOXY TERMINAL SEQUENCE; DNA REPAIR; DNA STRAND BREAKAGE; DNA SYNTHESIS; DNA TEMPLATE; GENE REARRANGEMENT; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN MOTIF; REGULATORY MECHANISM; REVIEW; SUMOYLATION;

DNA DAMAGE; DNA HELICASES; DNA POLYMERASE II; DNA POLYMERASE III; DNA REPAIR; DNA REPLICATION; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; MUTATION; PROLIFERATING CELL NUCLEAR ANTIGEN; RAD51 RECOMBINASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUMO-1 PROTEIN; SUMOYLATION; ULTRAVIOLET RAYS;

EID: 84875219980     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.9     Document Type: Review

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