QSAR study on hERG inhibitory effect of kappa opioid receptor antagonists by linear and non-linear methods

Medicinal Chemistry Research

Volumn 22, Issue 9, 2013, Pages 4047-4058

  Pourbasheer, Eslam ^a   Beheshti, Abolghasem ^a   Khajehsharifi, Habibollah ^b   Ganjali, Mohammad Reza ^a   Norouzi, Parviz ^a  

^a UNIVERSITY OF TEHRAN   (Iran)

^b YASOUJ UNIVERSITY   (Iran)

Author keywords

Genetic algorithm; Kappa opioid receptors; QSAR; Support vector machine

Indexed keywords

KAPPA OPIATE RECEPTOR ANTAGONIST; POTASSIUM CHANNEL HERG;

ARTICLE; CHEMICAL STRUCTURE; GENETIC ALGORITHM; PATTERN RECOGNITION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SUPPORT VECTOR MACHINE;

EID: 84881183407     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0412-4     Document Type: Article

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