Exploring QSARs for antiviral activity of 4-alkylamino-6-(2-hydroxyethyl)- 2-methylthiopyrimidines by support vector machine

Chemical Biology and Drug Design

Volumn 72, Issue 3, 2008, Pages 205-216

  Riahi, Siavash ^a   Pourbasheer, Eslam ^a   Dinarvand, Rassoul ^b   Ganjali, Mohammad Reza ^a   Norouzi, Parviz ^a  

^a UNIVERSITY OF TEHRAN   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antiviral activity; Chemometrics; Genetic algorithms; QSAR; Support vector machine

Indexed keywords

4 AMINO 6 (2 HYDROXYETHYL) 2 METHYLTHIOPYRIMIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ANTIVIRAL ACTIVITY; ARTICLE; CHEMOMETRIC ANALYSIS; COMPARATIVE STUDY; CORRELATION COEFFICIENT; CYTOTOXICITY; GENETIC ALGORITHM; LIPOPHILICITY; MULTIPLE LINEAR REGRESSION ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RELIABILITY; STATISTICAL PARAMETERS; SUPPORT VECTOR MACHINE;

ALGORITHMS; ANTIVIRAL AGENTS; DRUG DESIGN; LINEAR MODELS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; PYRIMIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SOLUBILITY;

EID: 50449092250     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2008.00695.x     Document Type: Article

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