메뉴 건너뛰기




Volumn 29, Issue 4, 2013, Pages 484-492

Valproic acid reduces autophagy and promotes functional recovery after spinal cord injury in rats

Author keywords

autophagy; Beclin 1; LC3; spinal cord injury; valproic acid

Indexed keywords

BECLIN 1; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; UNCLASSIFIED DRUG; VALPROIC ACID;

EID: 84881171157     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-013-1355-6     Document Type: Article
Times cited : (57)

References (33)
  • 1
    • 24944542337 scopus 로고    scopus 로고
    • Major causes of death among men and women in China
    • 16162883 10.1056/NEJMsa050467 1:CAS:528:DC%2BD2MXhtVWhsbnK
    • He J, Gu D, Wu X, Reynolds K, Duan X, Yao C, et al. Major causes of death among men and women in China. N Engl J Med 2005, 353:1124-1134.
    • (2005) N Engl J Med , vol.353 , pp. 1124-1134
    • He, J.1    Gu, D.2    Wu, X.3    Reynolds, K.4    Duan, X.5    Yao, C.6
  • 2
    • 19344376377 scopus 로고    scopus 로고
    • Assessing the burden of disease in the United States using disabilityadjusted life years
    • 15894144 10.1016/j.amepre.2005.02.009
    • McKenna MT, Michaud CM, Murray CJ, Marks JS. Assessing the burden of disease in the United States using disabilityadjusted life years. Am J Prev Med 2005, 28:415-423.
    • (2005) Am J Prev Med , vol.28 , pp. 415-423
    • McKenna, M.T.1    Michaud, C.M.2    Murray, C.J.3    Marks, J.S.4
  • 3
    • 1542573356 scopus 로고    scopus 로고
    • The burden of musculoskeletal conditions at the start of the new millennium
    • WHO Scientific Group on the Burden of Musculoskeletal Conditions at the start of the New Millennium
    • WHO Scientific Group on the Burden of Musculoskeletal Conditions at the start of the New Millennium. The burden of musculoskeletal conditions at the start of the new millennium. World Health Organ Tech Rep Ser 2003, 919:i-x, 1-218, back cover.
    • (2003) World Health Organ Tech Rep ser , vol.919 , Issue.1-10 , pp. 1-218
  • 4
    • 84873317670 scopus 로고    scopus 로고
    • An update on spinal cord injury research
    • 23124646 10.1007/s12264-012-1277-8
    • Cao HQ, Dong ED. An update on spinal cord injury research. Neurosci Bull 2013, 29:94-102.
    • (2013) Neurosci Bull , vol.29 , pp. 94-102
    • Cao, H.Q.1    Dong, E.D.2
  • 5
    • 79960102657 scopus 로고    scopus 로고
    • Secondary injury mechanisms in traumatic spinal cord injury: A nugget of this multiply cascade
    • Oyinbo CA. Secondary injury mechanisms in traumatic spinal cord injury: a nugget of this multiply cascade. Acta Neurobiol Exp (Wars) 2011, 71:281-299.
    • (2011) Acta Neurobiol Exp (Wars) , vol.71 , pp. 281-299
    • Oyinbo, C.A.1
  • 6
    • 33947682701 scopus 로고    scopus 로고
    • Trauma and aggressive homeostasis management
    • 17400155 10.1016/j.atc.2006.11.003
    • Baranov D, Neligan P. Trauma and aggressive homeostasis management. Anesthesiol Clin 2007, 25:49-63, viii.
    • (2007) Anesthesiol Clin , vol.25 , pp. 49-63
    • Baranov, D.1    Neligan, P.2
  • 7
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • 20965422 10.1016/j.molcel.2010.09.023 1:CAS:528:DC%2BC3cXhtlCjtr%2FM
    • Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010, 40:280-293.
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 8
    • 79956011038 scopus 로고    scopus 로고
    • Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice
    • 21463664 10.1016/j.neuroscience.2011.03.021 1:CAS:528: DC%2BC3MXmsVeqtLs%3D
    • Luo CL, Li BX, Li QQ, Chen XP, Sun YX, Bao HJ, et al. Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice. Neuroscience 2011, 184:54-63.
    • (2011) Neuroscience , vol.184 , pp. 54-63
    • Luo, C.L.1    Li, B.X.2    Li, Q.Q.3    Chen, X.P.4    Sun, Y.X.5    Bao, H.J.6
  • 9
    • 58149483522 scopus 로고    scopus 로고
    • Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death
    • 18948195 10.1016/j.nbd.2008.09.009 1:CAS:528:DC%2BD1MXnslSmuw%3D%3D
    • Kanno H, Ozawa H, Sekiguchi A, Itoi E. Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death. Neurobiol Dis 2009, 33:143-148.
    • (2009) Neurobiol Dis , vol.33 , pp. 143-148
    • Kanno, H.1    Ozawa, H.2    Sekiguchi, A.3    Itoi, E.4
  • 10
    • 65249104617 scopus 로고    scopus 로고
    • The role of autophagy in spinal cord injury
    • 19158496 10.4161/auto.5.3.7724 1:CAS:528:DC%2BD1MXnvVyrsrk%3D
    • Kanno H, Ozawa H, Sekiguchi A, Itoi E. The role of autophagy in spinal cord injury. Autophagy 2009, 5:390-392.
    • (2009) Autophagy , vol.5 , pp. 390-392
    • Kanno, H.1    Ozawa, H.2    Sekiguchi, A.3    Itoi, E.4
  • 11
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • 18006683 10.1101/gad.1599207 1:CAS:528:DC%2BD2sXhtlGmsrjP
    • Mizushima N. Autophagy: process and function. Genes Dev 2007, 21:2861-2873.
    • (2007) Genes Dev , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 12
    • 34548265278 scopus 로고    scopus 로고
    • Autophagy and human disease
    • 17671424 10.4161/cc.6.15.4511 1:CAS:528:DC%2BD2sXhtFWmurfM
    • Huang J, Klionsky DJ. Autophagy and human disease. Cell Cycle 2007, 6:1837-1849.
    • (2007) Cell Cycle , vol.6 , pp. 1837-1849
    • Huang, J.1    Klionsky, D.J.2
  • 13
    • 84871464536 scopus 로고    scopus 로고
    • Neuronal autophagy in cerebral ischemia
    • 22968594 10.1007/s12264-012-1268-9 1:CAS:528:DC%2BC38XhsVKhu7%2FL
    • Xu F, Gu JH, Qin ZH. Neuronal autophagy in cerebral ischemia. Neurosci Bull 2012, 28:658-666.
    • (2012) Neurosci Bull , vol.28 , pp. 658-666
    • Xu, F.1    Gu, J.H.2    Qin, Z.H.3
  • 14
    • 77951228508 scopus 로고    scopus 로고
    • Hypoxia-induced autophagy: Cell death or cell survival?
    • 20022734 10.1016/j.ceb.2009.11.015 1:CAS:528:DC%2BC3cXks1Srtb8%3D
    • Mazure NM, Pouyssegur J. Hypoxia-induced autophagy: cell death or cell survival? Curr Opin Cell Biol 2010, 22: 177-180.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 177-180
    • Mazure, N.M.1    Pouyssegur, J.2
  • 15
    • 80053970026 scopus 로고    scopus 로고
    • Induction of autophagy and autophagic cell death in damaged neural tissue after acute spinal cord injury in mice
    • 10.1097/BRS.0b013e3182028c3a
    • Kanno H, Ozawa H, Sekiguchi A, Yamaya S, Itoi E. Induction of autophagy and autophagic cell death in damaged neural tissue after acute spinal cord injury in mice. Spine (Phila Pa 1976) 2011, 36:E1427-1434.
    • (2011) Spine (Phila Pa 1976) , vol.36 , pp. 1427-1434
    • Kanno, H.1    Ozawa, H.2    Sekiguchi, A.3    Yamaya, S.4    Itoi, E.5
  • 16
    • 84858800745 scopus 로고    scopus 로고
    • Autophagy is activated in injured neurons and inhibited by methylprednisolone after experimental spinal cord injury
    • 10.1097/BRS.0b013e318221e859
    • Chen HC, Fong TH, Lee AW, Chiu WT. Autophagy is activated in injured neurons and inhibited by methylprednisolone after experimental spinal cord injury. Spine (Phila Pa 1976) 2012, 37:470-475.
    • (2012) Spine (Phila Pa 1976) , vol.37 , pp. 470-475
    • Chen, H.C.1    Fong, T.H.2    Lee, A.W.3    Chiu, W.T.4
  • 17
    • 84855588783 scopus 로고    scopus 로고
    • Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury
    • 22253859 10.1371/journal.pone.0030012 1:CAS:528:DC%2BC38Xht12mu78%3D
    • Walker CL, Walker MJ, Liu NK, Risberg EC, Gao X, Chen J, et al. Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury. PLoS One 2012, 7:e30012.
    • (2012) PLoS One , vol.7 , pp. 30012
    • Walker, C.L.1    Walker, M.J.2    Liu, N.K.3    Risberg, E.C.4    Gao, X.5    Chen, J.6
  • 18
    • 0037728684 scopus 로고    scopus 로고
    • Valproic acid enhances axonal regeneration and recovery of motor function after sciatic nerve axotomy in adult rats
    • 12763612 10.1016/S0006-8993(03)02699-4 1:CAS:528:DC%2BD3sXjvV2ltrk%3D
    • Cui SS, Yang CP, Bowen RC, Bai O, Li XM, Jiang W, et al. Valproic acid enhances axonal regeneration and recovery of motor function after sciatic nerve axotomy in adult rats. Brain Res 2003, 975:229-236.
    • (2003) Brain Res , vol.975 , pp. 229-236
    • Cui, S.S.1    Yang, C.P.2    Bowen, R.C.3    Bai, O.4    Li, X.M.5    Jiang, W.6
  • 19
    • 77956197481 scopus 로고    scopus 로고
    • Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats
    • 20614021 10.1371/journal.pone.0011383
    • Dash PK, Orsi SA, Zhang M, Grill RJ, Pati S, Zhao J, et al. Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats. PLoS One 2010, 5:e11383.
    • (2010) PLoS One , vol.5 , pp. 11383
    • Dash, P.K.1    Orsi, S.A.2    Zhang, M.3    Grill, R.J.4    Pati, S.5    Zhao, J.6
  • 20
    • 34147199586 scopus 로고    scopus 로고
    • Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation
    • 17398106 10.1016/j.nbd.2007.02.006 1:CAS:528:DC%2BD2sXkt1aitrg%3D
    • Sinn DI, Kim SJ, Chu K, Jung KH, Lee ST, Song EC, et al. Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation. Neurobiol Dis 2007, 26:464-472.
    • (2007) Neurobiol Dis , vol.26 , pp. 464-472
    • Sinn, D.I.1    Kim, S.J.2    Chu, K.3    Jung, K.H.4    Lee, S.T.5    Song, E.C.6
  • 21
    • 79957769597 scopus 로고    scopus 로고
    • Valproic acid improves outcome after rodent spinal cord injury: Potential roles of histone deacetylase inhibition
    • 21439269 10.1016/j.brainres.2011.03.040 1:CAS:528:DC%2BC3MXmvVejtr0%3D
    • Lv L, Sun Y, Han X, Xu CC, Tang YP, Dong Q. Valproic acid improves outcome after rodent spinal cord injury: potential roles of histone deacetylase inhibition. Brain Res 2011, 1396:60-68.
    • (2011) Brain Res , vol.1396 , pp. 60-68
    • Lv, L.1    Sun, Y.2    Han, X.3    Xu, C.C.4    Tang, Y.P.5    Dong, Q.6
  • 22
    • 77954643043 scopus 로고    scopus 로고
    • Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines
    • 20308311 10.1093/neuonc/nop005 1:CAS:528:DC%2BC3cXotlCmsb0%3D
    • Fu J, Shao CJ, Chen FR, Ng HK, Chen ZP. Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines. Neuro Oncol 2010, 12:328-340.
    • (2010) Neuro Oncol , vol.12 , pp. 328-340
    • Fu, J.1    Shao, C.J.2    Chen, F.R.3    Ng, H.K.4    Chen, Z.P.5
  • 23
    • 84858407568 scopus 로고    scopus 로고
    • Rapamycin promotes autophagy and reduces neural tissue damage and locomotor impairment after spinal cord injury in mice
    • 21806471 10.1089/neu.2011.1919
    • Sekiguchi A, Kanno H, Ozawa H, Yamaya S, Itoi E. Rapamycin promotes autophagy and reduces neural tissue damage and locomotor impairment after spinal cord injury in mice. J Neurotrauma 2012, 29:946-956.
    • (2012) J Neurotrauma , vol.29 , pp. 946-956
    • Sekiguchi, A.1    Kanno, H.2    Ozawa, H.3    Yamaya, S.4    Itoi, E.5
  • 24
    • 0026802223 scopus 로고
    • A monitored contusion model of spinal cord injury in the rat
    • 1404425 10.1089/neu.1992.9.123 1:STN:280:DyaK3s%2FitFWltw%3D%3D
    • Gruner JA. A monitored contusion model of spinal cord injury in the rat. J Neurotrauma 1992, 9:123-126; discussion 126-128.
    • (1992) J Neurotrauma , vol.9 , pp. 123-126
    • Gruner, J.A.1
  • 25
    • 34248530339 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: Multiple mechanisms of action
    • 17371805 10.1124/jpet.107.120188 1:CAS:528:DC%2BD2sXmsFeru7o%3D
    • Kim HJ, Rowe M, Ren M, Hong JS, Chen PS, Chuang DM. Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther 2007, 321:892-901.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 892-901
    • Kim, H.J.1    Rowe, M.2    Ren, M.3    Hong, J.S.4    Chen, P.S.5    Chuang, D.M.6
  • 26
    • 84873749490 scopus 로고    scopus 로고
    • Quantitative analysis of histological staining and fluorescence using imageJ
    • 10.1002/ar.22554
    • Jensen EC. Quantitative analysis of histological staining and fluorescence using imageJ. Anat Rec (Hoboken) 2013, 296:378-381.
    • (2013) Anat Rec (Hoboken) , vol.296 , pp. 378-381
    • Jensen, E.C.1
  • 27
    • 0030157694 scopus 로고    scopus 로고
    • Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
    • 8654527 10.1006/exnr.1996.0098 1:STN:280:DyaK283jt1eiuw%3D%3D
    • Basso DM, Beattie MS, Bresnahan JC. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp Neurol 1996, 139:244-256.
    • (1996) Exp Neurol , vol.139 , pp. 244-256
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 28
    • 0036797791 scopus 로고    scopus 로고
    • A statistical method for analyzing rating scale data: The BBB locomotor score
    • 12427332 10.1089/08977150260338038
    • Scheff SW, Saucier DA, Cain ME. A statistical method for analyzing rating scale data: the BBB locomotor score. J Neurotrauma 2002, 19:1251-1260.
    • (2002) J Neurotrauma , vol.19 , pp. 1251-1260
    • Scheff, S.W.1    Saucier, D.A.2    Cain, M.E.3
  • 29
    • 27644514227 scopus 로고    scopus 로고
    • Another way to die: Autophagic programmed cell death
    • 16247500 10.1038/sj.cdd.4401777 1:CAS:528:DC%2BD2MXhtFCjt7%2FL
    • Tsujimoto Y, Shimizu S. Another way to die: autophagic programmed cell death. Cell Death Differ 2005, 12(Suppl 2):1528-1534.
    • (2005) Cell Death Differ , vol.12 , Issue.SUPPL. 2 , pp. 1528-1534
    • Tsujimoto, Y.1    Shimizu, S.2
  • 30
    • 84857301687 scopus 로고    scopus 로고
    • Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage
    • 22248716 10.4161/auto.8.2.18599 1:CAS:528:DC%2BC38XlvFOju78%3D
    • Viscomi MT, D'Amelio M, Cavallucci V, Latini L, Bisicchia E, Nazio F, et al. Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage. Autophagy 2012, 8:222-235.
    • (2012) Autophagy , vol.8 , pp. 222-235
    • Viscomi, M.T.1    D'Amelio, M.2    Cavallucci, V.3    Latini, L.4    Bisicchia, E.5    Nazio, F.6
  • 31
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • 18191218 10.1016/j.cell.2007.12.018 1:CAS:528:DC%2BD1cXhtFehtb8%3D
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 32
    • 34250894388 scopus 로고    scopus 로고
    • BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)
    • 17438366 1:CAS:528:DC%2BD2sXhtVGrtLfJ
    • Maiuri MC, Criollo A, Tasdemir E, Vicencio JM, Tajeddine N, Hickman JA, et al. BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L). Autophagy 2007, 3:374-376.
    • (2007) Autophagy , vol.3 , pp. 374-376
    • Maiuri, M.C.1    Criollo, A.2    Tasdemir, E.3    Vicencio, J.M.4    Tajeddine, N.5    Hickman, J.A.6
  • 33
    • 13844309711 scopus 로고    scopus 로고
    • Clinical development of histone deacetylase inhibitors as anticancer agents
    • 15822187 10.1146/annurev.pharmtox.45.120403.095825 1:CAS:528: DC%2BD2MXisVWjtLs%3D
    • Drummond DC, Noble CO, Kirpotin DB, Guo Z, Scott GK, Benz CC. Clinical development of histone deacetylase inhibitors as anticancer agents. Annu Rev Pharmacol Toxicol 2005, 45:495-528.
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 495-528
    • Drummond, D.C.1    Noble, C.O.2    Kirpotin, D.B.3    Guo, Z.4    Scott, G.K.5    Benz, C.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.