The novel purification and biochemical characterization of a reversible CYP24A1:adrenodoxin complex

Journal of Steroid Biochemistry and Molecular Biology

Volumn 136, Issue 1, 2013, Pages 47-53

  Hartfield, Kimberly A ^a   Stout, C David ^a   Annalora, Andrew J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Adrenodoxin; Adx; CYP24A1; Cytochrome P450 24A1; Membrane protein crystallography; Mitochondrial P450; Rational drug development; Vitamin D metabolism

Indexed keywords

1,25 DIHYDROXYERGOCALCIFEROL; 3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 1 PROPANESULFONIC ACID; ADRENODOXIN; DETERGENT; MEMBRANE PROTEIN; PROTEIN CYP24A1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; BINDING AFFINITY; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; CRYSTALLIZATION; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME PURIFICATION; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; EXPRESSION VECTOR; LIGAND BINDING; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STABILITY; REVIEW; SPECTROSCOPY; X RAY CRYSTALLOGRAPHY;

BOVINAE; RATTUS;

EID: 84881162529     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.11.001     Document Type: Review

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