NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy

Kidney International

Volumn 84, Issue 2, 2013, Pages 265-276

  Du, Pengchao ^a   Fan, Baoxia ^a   Han, Huirong ^a   Zhen, Junhui ^a   Shang, Jin ^a   Wang, Xiaojie ^a   Li, Xiang ^a   Shi, Weichen ^a   Tang, Wei ^a   Bao, Chanchan ^b   Wang, Ziying ^a   Zhang, Yan ^a   Zhang, Bin ^a   Wei, Xinbing ^a   Yi, Fan ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Diabetic nephropathy; Immune homeostasis; Insulin resistance; NLR family; Podocytes

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CASPASE RECRUITMENT DOMAIN PROTEIN 15; GLUCOSE; NEPHRIN; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE EXACERBATION; DOWN REGULATION; GLUCOSE TRANSPORT; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; INSULIN RESISTANCE; KIDNEY BIOPSY; KIDNEY INJURY; LIPID DIET; MALE; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES; UPREGULATION;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; CELLS, CULTURED; CREATININE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DIET, HIGH-FAT; FEMALE; GLUCOSE TRANSPORTER TYPE 4; HUMANS; INFLAMMATION MEDIATORS; INSULIN; INSULIN RESISTANCE; LIPIDS; MALE; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MIDDLE AGED; NEPHRITIS; NOD2 SIGNALING ADAPTOR PROTEIN; PODOCYTES; TIME FACTORS; UP-REGULATION;

EID: 84881158042     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.113     Document Type: Article

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