Fenofibrate suppresses melanogenesis in B16-F10 melanoma cells via activation of the p38 mitogen-activated protein kinase pathway

Chemico-Biological Interactions

Volumn 205, Issue 3, 2013, Pages 157-164

  Huang, Yu Chun ^a   Liu, Kao Chih ^a   Chiou, Yi Ling ^a   Yang, Chao Hsun ^a   Chen, Tien Hui ^b   Li, Ting Ting ^a   Liu, Li Ling ^a  

^a PROVIDENCE UNIVERSITY   (Taiwan)

^b CHANG BING SHOW CHWAN MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Fenofibrate; Liver X receptor; Melanocortin 1 receptor; p38 Mitogen activated protein kinase; Peroxisome proliferator activated receptor; Tyrosinase

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; DOPA; FENOFIBRATE; LIVER X RECEPTOR; MELANIN; MELANOCORTIN 1 RECEPTOR; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOPHENOL MONOOXYGENASE; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN B16 F10; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MELANOGENESIS; MELANOMA CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

FENOFIBRATE; LIVER X RECEPTOR; MELANOCORTIN 1 RECEPTOR; P38 MITOGEN-ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; TYROSINASE;

BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; FENOFIBRATE; HUMANS; IMIDAZOLES; MAP KINASE SIGNALING SYSTEM; MELANINS; MELANOMA, EXPERIMENTAL; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; OXAZOLES; PPAR ALPHA; PYRIDINES; REAL-TIME POLYMERASE CHAIN REACTION; RNA; TYROSINE;

EID: 84881149249     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.07.008     Document Type: Article

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