Microglial P2Y12 Deficiency/Inhibition Protects against Brain Ischemia

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Webster, Corey M ^a   Hokari, Masaaki ^a   McManus, April ^a   Tang, Xian Nan ^a   Ma, Hualong ^a   Kacimi, Rachid ^a   Yenari, Midori A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOPIDOGREL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PURINERGIC P2Y12 RECEPTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; DRUG DERIVATIVE; GLUCOSE; P2RY12 PROTEIN, MOUSE; PURINERGIC P2Y RECEPTOR ANTAGONIST; TICLOPIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; CELL ACTIVATION; CELL MIGRATION; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROGLIA; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPATHOLOGY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PROTEIN FUNCTION; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL CULTURE; CELL HYPOXIA; CELL MOTION; CELL SURVIVAL; COCULTURE; GENETICS; HIPPOCAMPAL CA1 REGION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY; ANALOGS AND DERIVATIVES; DEFICIENCY;

ANIMALS; APOPTOSIS; ASTROCYTES; BRAIN ISCHEMIA; CA1 REGION, HIPPOCAMPAL; CELL HYPOXIA; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; GENE KNOCKDOWN TECHNIQUES; GLUCOSE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NEURONS; NF-KAPPA B; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2Y12; TICLOPIDINE;

EID: 84881116173     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070927     Document Type: Article

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