Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 31, 2013, Pages

  Reiterer, Veronika ^a   Fey, Dirk ^b   Kolch, Walter ^b,c   Kholodenko, Boris N ^b,c   Farhan, Hesso ^a,d  

^a UNIVERSITY OF KONSTANZ   (Switzerland)

^b Systems Biology   (Ireland)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

Computational modeling; MAPK

Indexed keywords

DUAL SPECIFICITY PHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATASE; SERINE THREONINE TYROSINE INTERACTING PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; DUSP4 PROTEIN, HUMAN; DUSP4 PROTEIN, RAT; MAPK1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE; NUCLEAR PROTEIN; SIGNAL PEPTIDE; STYX PROTEIN, HUMAN; STYX PROTEIN, RAT;

ARTICLE; BINDING COMPETITION; CELL DIFFERENTIATION; CELL FATE; CELL MIGRATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME BINDING; ENZYME PHOSPHORYLATION; GOLGI COMPLEX; MOLECULAR MODEL; NUCLEOCYTOPLASMIC TRANSPORT; PC12 CELL; POLARIZATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; ANIMAL; CELL MOTION; GENE SILENCING; GENETICS; HUMAN; METABOLISM; PC12 CELL LINE; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL NUCLEUS; DUAL-SPECIFICITY PHOSPHATASES; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; GOLGI APPARATUS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE PHOSPHATASES; NUCLEAR PROTEINS; PC12 CELLS; RATS;

EID: 84881108561     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1301985110     Document Type: Article

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