-
1
-
-
0033215340
-
Two co-existing mechanisms for nuclear import of MAP kinase: Passive diffusion of a monomer and active transport of a dimer
-
Adachi M, Fukuda M, Nishida E (1999) Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer. EMBO J 18: 5347-5358
-
(1999)
EMBO J
, vol.18
, pp. 5347-5358
-
-
Adachi, M.1
Fukuda, M.2
Nishida, E.3
-
2
-
-
0034610996
-
Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism
-
Adachi M, Fukuda M, Nishida E (2000) Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism. J Cell Biol 148: 849-856
-
(2000)
J Cell Biol
, vol.148
, pp. 849-856
-
-
Adachi, M.1
Fukuda, M.2
Nishida, E.3
-
3
-
-
3543020265
-
Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells
-
Ajenjo N, Canon E, Sanchez-Perez I, Matallanas D, Leon J, Perona R, Crespo P (2004) Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells. J Biol Chem 279: 32813-32823
-
(2004)
J Biol Chem
, vol.279
, pp. 32813-32823
-
-
Ajenjo, N.1
Canon, E.2
Sanchez-Perez, I.3
Matallanas, D.4
Leon, J.5
Perona, R.6
Crespo, P.7
-
4
-
-
0035971144
-
A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission
-
Bardwell AJ, Flatauer LJ, Matsukuma K, Thorner J, Bardwell L (2001) A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission. J Biol Chem 276: 10374-10386
-
(2001)
J Biol Chem
, vol.276
, pp. 10374-10386
-
-
Bardwell, A.J.1
Flatauer, L.J.2
Matsukuma, K.3
Thorner, J.4
Bardwell, L.5
-
5
-
-
0032563807
-
Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2
-
Ben-Levy R, Hooper S, Wilson R, Paterson HF, Marshall CJ (1998) Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2. Curr Biol 8: 1049-1057
-
(1998)
Curr Biol
, vol.8
, pp. 1049-1057
-
-
Ben-Levy, R.1
Hooper, S.2
Wilson, R.3
Paterson, H.F.4
Marshall, C.J.5
-
6
-
-
0033552609
-
A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase
-
Blanco-Aparicio C, Torres J, Pulido R (1999) A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase. J Cell Biol 147: 1129-1136
-
(1999)
J Cell Biol
, vol.147
, pp. 1129-1136
-
-
Blanco-Aparicio, C.1
Torres, J.2
Pulido, R.3
-
7
-
-
13544252820
-
Live Cell Imaging of ERK and MEK: Simple binding equilibrium explains the regulated nucleocytoplasmic distribution of ERK
-
Burack WR, Shaw AS (2005) Live Cell Imaging of ERK and MEK: simple binding equilibrium explains the regulated nucleocytoplasmic distribution of ERK. J Biol Chem 280: 3832-3837
-
(2005)
J Biol Chem
, vol.280
, pp. 3832-3837
-
-
Burack, W.R.1
Shaw, A.S.2
-
8
-
-
29144536766
-
Quantifying ERK2-protein interactions by fluorescence anisotropy: PEA-15 inhibits ERK2 by blocking the binding of DEJL domains
-
Callaway K, Rainey MA, Dalby KN (2005) Quantifying ERK2-protein interactions by fluorescence anisotropy: PEA-15 inhibits ERK2 by blocking the binding of DEJL domains. Biochim Biophys Acta 1754: 316-323
-
(2005)
Biochim Biophys Acta
, vol.1754
, pp. 316-323
-
-
Callaway, K.1
Rainey, M.A.2
Dalby, K.N.3
-
9
-
-
0036133133
-
Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2
-
Esparis-Ogando A, Diaz-Rodriguez E, Montero JC, Yuste L, Crespo P, Pandiella A (2002) Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2. Mol Cell Biol 22: 270-285
-
(2002)
Mol Cell Biol
, vol.22
, pp. 270-285
-
-
Esparis-Ogando, A.1
Diaz-Rodriguez, E.2
Montero, J.C.3
Yuste, L.4
Crespo, P.5
Pandiella, A.6
-
10
-
-
0023293153
-
Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores
-
Finlay DR, Newmeyer DD, Price TM, Forbes DJ (1987) Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores. J Cell Biol 104: 189-200
-
(1987)
J Cell Biol
, vol.104
, pp. 189-200
-
-
Finlay, D.R.1
Newmeyer, D.D.2
Price, T.M.3
Forbes, D.J.4
-
11
-
-
18044405015
-
PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase
-
Formstecher E, Ramos JW, Fauquet M, Calderwood DA, Hsieh JC, Canton B, Nguyen XT, Barnier JV, Camonis J, Ginsberg MH, Chneiweiss H (2001) PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase. Dev Cell 1: 239-250
-
(2001)
Dev Cell
, vol.1
, pp. 239-250
-
-
Formstecher, E.1
Ramos, J.W.2
Fauquet, M.3
Calderwood, D.A.4
Hsieh, J.C.5
Canton, B.6
Nguyen, X.T.7
Barnier, J.V.8
Camonis, J.9
Ginsberg, M.H.10
Chneiweiss, H.11
-
12
-
-
0030831534
-
CRM1 is responsible for intracellular transport mediated by the nuclear export signal
-
Fukuda M, Asano S, Nakamura T, Adachi M, Yoshida M, Yanagida M, Nishida E (1997a) CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature 390: 308-311
-
(1997)
Nature
, vol.390
, pp. 308-311
-
-
Fukuda, M.1
Asano, S.2
Nakamura, T.3
Adachi, M.4
Yoshida, M.5
Yanagida, M.6
Nishida, E.7
-
13
-
-
0030972494
-
Interaction of MAP kinase with MAP kinase kinas: Its possible role in the control of nucleocytoplasmic transport of MAP kinase
-
Fukuda M, Gotoh Y, Nishida E (1997b) Interaction of MAP kinase with MAP kinase kinas: its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J 16: 1901-1908
-
(1997)
EMBO J
, vol.16
, pp. 1901-1908
-
-
Fukuda, M.1
Gotoh, Y.2
Nishida, E.3
-
14
-
-
0033555229
-
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase
-
Jacobs D, Glossip D, Xing H, Muslin AJ, Kornfeld K (1999) Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase. Genes Dev 13: 163-175
-
(1999)
Genes Dev
, vol.13
, pp. 163-175
-
-
Jacobs, D.1
Glossip, D.2
Xing, H.3
Muslin, A.J.4
Kornfeld, K.5
-
15
-
-
0032524356
-
Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation
-
Khokhlatchev AV, Canagarajah B, Wilsbacher J, Robinson M, Atkinson M, Goldsmith E, Cobb MH (1998) Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation. Cell 93: 605-615
-
(1998)
Cell
, vol.93
, pp. 605-615
-
-
Khokhlatchev, A.V.1
Canagarajah, B.2
Wilsbacher, J.3
Robinson, M.4
Atkinson, M.5
Goldsmith, E.6
Cobb, M.H.7
-
16
-
-
1842665655
-
Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry
-
Lee T, Hoofnagle AN, Kabuyama Y, Stroud J, Min X, Goldsmith EJ, Chen L, Resing KA, Ahn NG (2004) Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry. Mol Cell 14: 43-55
-
(2004)
Mol Cell
, vol.14
, pp. 43-55
-
-
Lee, T.1
Hoofnagle, A.N.2
Kabuyama, Y.3
Stroud, J.4
Min, X.5
Goldsmith, E.J.6
Chen, L.7
Resing, K.A.8
Ahn, N.G.9
-
17
-
-
0027283659
-
-
Lenormand P, Sardet C, Pages G, L'Allemain G, Brunet A, Pouyssegur J (1993) Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts. J Cell Biol 122: 1079-1088
-
Lenormand P, Sardet C, Pages G, L'Allemain G, Brunet A, Pouyssegur J (1993) Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts. J Cell Biol 122: 1079-1088
-
-
-
-
18
-
-
0035834689
-
Evidence for existence of a nuclear pore complex-mediated, cytosol-independent pathway of nuclear translocation of ERK MAP kinase in permeabilized cells
-
Matsubayashi Y, Fukuda M, Nishida E (2001) Evidence for existence of a nuclear pore complex-mediated, cytosol-independent pathway of nuclear translocation of ERK MAP kinase in permeabilized cells. J Biol Chem 276: 41755-41760
-
(2001)
J Biol Chem
, vol.276
, pp. 41755-41760
-
-
Matsubayashi, Y.1
Fukuda, M.2
Nishida, E.3
-
19
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
-
Pearson G, Robinson F, Gibson TG, Xu B, Karandikar M, Berman K, Cobb MH (2001) Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Revs 22: 153-183
-
(2001)
Endocr Revs
, vol.22
, pp. 153-183
-
-
Pearson, G.1
Robinson, F.2
Gibson, T.G.3
Xu, B.4
Karandikar, M.5
Berman, K.6
Cobb, M.H.7
-
20
-
-
0041926731
-
Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
-
Pouyssegur J, Lenormand P (2003) Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Eur J Biochem 270: 3291-3299
-
(2003)
Eur J Biochem
, vol.270
, pp. 3291-3299
-
-
Pouyssegur, J.1
Lenormand, P.2
-
21
-
-
33744941875
-
The nuclear localization of ERK2 occurs by mechanisms both independent of and dependent on energy
-
Ranganathan A, Yazicioglu MN, Cobb MH (2006) The nuclear localization of ERK2 occurs by mechanisms both independent of and dependent on energy. J Biol Chem 281: 15645-15652
-
(2006)
J Biol Chem
, vol.281
, pp. 15645-15652
-
-
Ranganathan, A.1
Yazicioglu, M.N.2
Cobb, M.H.3
-
22
-
-
0029026860
-
Association of mitogen-activated protein kinase with the microtubule cytoskeleton
-
Reszka AA, Seger R, Diltz CD, Krebs EG, Fischer EH (1995) Association of mitogen-activated protein kinase with the microtubule cytoskeleton. Proc Natl Acad Sci USA 92: 8881-8885
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8881-8885
-
-
Reszka, A.A.1
Seger, R.2
Diltz, C.D.3
Krebs, E.G.4
Fischer, E.H.5
-
23
-
-
0032558692
-
A constitutively active and nuclear form of MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation
-
Robinson MJ, Stippec SA, Goldsmith E, White MA, Cobb MH (1998) A constitutively active and nuclear form of MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation. Curr Biol 8: 1141-1150
-
(1998)
Curr Biol
, vol.8
, pp. 1141-1150
-
-
Robinson, M.J.1
Stippec, S.A.2
Goldsmith, E.3
White, M.A.4
Cobb, M.H.5
-
24
-
-
0034595828
-
Distinct carboxi-termini confer divergent characteristics to the mitogen-activated protein kinase p38a and its splice isoform Mxi2
-
Sanz V, Arozarena I, Crespo P (2000) Distinct carboxi-termini confer divergent characteristics to the mitogen-activated protein kinase p38a and its splice isoform Mxi2. FEBS Lett 474: 169-174
-
(2000)
FEBS Lett
, vol.474
, pp. 169-174
-
-
Sanz, V.1
Arozarena, I.2
Crespo, P.3
-
25
-
-
0038727006
-
p38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levels
-
Sanz-Moreno V, Casar B, Crespo P (2003) p38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levels. Mol Cell Biol 23: 3079-3090
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3079-3090
-
-
Sanz-Moreno, V.1
Casar, B.2
Crespo, P.3
-
26
-
-
0032555891
-
Activation of the MKK/ERK pathway during somatic cell mitosis: Direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen
-
Shapiro PS, Vaisberg E, Hunt AJ, Tolwinski NS, Whalen AM, McIntosh JR, Ahn NG (1998) Activation of the MKK/ERK pathway during somatic cell mitosis: direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen. J Cell Biol 142: 1533-1545
-
(1998)
J Cell Biol
, vol.142
, pp. 1533-1545
-
-
Shapiro, P.S.1
Vaisberg, E.2
Hunt, A.J.3
Tolwinski, N.S.4
Whalen, A.M.5
McIntosh, J.R.6
Ahn, N.G.7
-
27
-
-
1842581898
-
The death effector domain protein PEA-15 prevents nuclear entry of ERK2 by inhibiting required interactions
-
Whitehurst AW, Robinson FL, Moore MS, Cobb MH (2004) The death effector domain protein PEA-15 prevents nuclear entry of ERK2 by inhibiting required interactions. J Biol Chem 279: 12840-12847
-
(2004)
J Biol Chem
, vol.279
, pp. 12840-12847
-
-
Whitehurst, A.W.1
Robinson, F.L.2
Moore, M.S.3
Cobb, M.H.4
-
28
-
-
0037188473
-
ERK2 enters the nucleus by a carrier-independent mechanism
-
Whitehurst AW, Wilsbacher JL, You Y, Luby-Phelps K, Moore MS, Cobb MH (2002) ERK2 enters the nucleus by a carrier-independent mechanism. Proc Natl Acad Sci USA 99: 7496-7501
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7496-7501
-
-
Whitehurst, A.W.1
Wilsbacher, J.L.2
You, Y.3
Luby-Phelps, K.4
Moore, M.S.5
Cobb, M.H.6
-
29
-
-
0035816678
-
Involvement of the activation loop of ERK in the detachment from cytosolic anchoring
-
Wolf I, Rubinfeld H, Yoon S, Marmor G, Hanoch T, Seger R (2001) Involvement of the activation loop of ERK in the detachment from cytosolic anchoring. J Biol Chem 276: 24490-24497
-
(2001)
J Biol Chem
, vol.276
, pp. 24490-24497
-
-
Wolf, I.1
Rubinfeld, H.2
Yoon, S.3
Marmor, G.4
Hanoch, T.5
Seger, R.6
-
30
-
-
0028818395
-
Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates max protein
-
Zervos AS, Faccio L, Gatto JP, Kyriakis JM, Brent R (1995) Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates max protein. Proc Natl Acad Sci USA 92: 10531-10534
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10531-10534
-
-
Zervos, A.S.1
Faccio, L.2
Gatto, J.P.3
Kyriakis, J.M.4
Brent, R.5
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