Effects of agomelatine on oxidative stress in the brain of mice after chemically induced seizures

Cellular and Molecular Neurobiology

Volumn 33, Issue 6, 2013, Pages 825-835

  Aguiar, Carlos Clayton Torres ^a   Almeida, Anália Barbosa ^b   Araújo, Paulo Victor Pontes ^b   Vasconcelos, Germana Silva ^b   Chaves, Edna Maria Camelo ^b   Do Vale, Otoni Cardoso ^b   Macêdo, Danielle Silveira ^b   Leal, Luzia Kalyne Almeida Moreira ^b   De Barros Viana, Glauce Socorro ^b   Vasconcelos, Silvânia Maria Mendes ^b  

^a UNIVERSITY OF FORTALEZA   (Brazil)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Agomelatine; Antioxidant effect; Melatonin; Reactive oxygen species; Seizure

Indexed keywords

AGOMELATINE; CATALASE; MELATONIN; NITRITE; PENTETRAZOLE; PICROTOXIN; PILOCARPINE; STRYCHNINE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; ACETAMIDE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; FEMALE; HIPPOCAMPUS; LIPID PEROXIDATION; LOW DRUG DOSE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PREFRONTAL CORTEX; PRIORITY JOURNAL; SEIZURE; ANIMAL; BRAIN; CHEMICALLY INDUCED; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PATHOLOGY;

MUS; STRYCHNOS TOXIFERA;

ACETAMIDES; ANIMALS; BRAIN; CATALASE; FEMALE; LIPID PEROXIDATION; MICE; NITRITES; OXIDATIVE STRESS; PENTYLENETETRAZOLE; PICROTOXIN; PILOCARPINE; SEIZURES; STRYCHNINE;

EID: 84881104652     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-013-9949-0     Document Type: Article

References (53)

1. Aguiar CC, Almeida AB, Araujo PV, Vasconcelos GS, Chaves EM, do Vale OC, Macedo DS, de Sousa FC, Viana GS, Vasconcelos SM (2012) Anticonvulsant effects of agomelatine in mice. Epilepsy Behav 24:324-328
2. Akula KK, Dhir A, Kulkarni SK (2007) Systemic administration of adenosine ameliorates pentylenetetrazol-induced chemical kindling and secondary behavioural and biochemical changes in mice. Fundam Clin Pharmacol 21:583-594
3. Banach M, Gurdziel E, Jedrych M, Borowicz KK (2011) Melatonin in experimental seizures and epilepsy. Pharmacol Rep 63:1-11
4. Betz H, Becker CM (1988) The mammalian glycine receptor: biology and structure of a neuronal chloride channel protein. Neurochem Int 13:137-146
5. Buznego MT, Perez-Saad H (2004) Acute effect of an extract of Ambrosia paniculata (Willd.) O. E. Schultz (mugwort) in several models of experimental epilepsy. Epilepsy Behav 5:847-851
6. Buznego MT, Perez-Saad H (2006) Behavioral and antiepileptic effect of acute administration of the extract of the aquatic plant Echinodorus berteroi (Sprengel) Fassett (upright burhead). Epilepsy Behav 9:40-45
7. Caballero B, Vega-Naredo I, Sierra V, Huidobro-Fernandez C, Soria-Valles C, De Gonzalo-Calvo D, Tolivia D, Gutierrez-Cuesta J, Pallas M, Camins A, Rodriguez-Colunga MJ, Coto-Montes A (2008) Favorable effects of a prolonged treatment with melatonin on the level of oxidative damage and neurodegeneration in senescence-accelerated mice. J Pineal Res 45:302-311
8. Carmans S, Hendriks JJ, Thewissen K, Van den Eynden J, Stinissen P, Rigo JM, Hellings N (2010) The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transporters. J Neurosci Res 88:2420-2430
9. Chagraoui A, Protais P, Filloux T, Mocaer E (2003) Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats. Psychopharmacology 170:17-22
10. Chen SD, Chang AY, Chuang YC (2010) The potential role of mitochondrial dysfunction in seizure-associated cell death in the hippocampus and epileptogenesis. J Bioenerg Biomembr 42:461-465
11. Chern CM, Liao JF, Wang YH, Shen YC (2012) Melatonin ameliorates neural function by promoting endogenous neurogenesis through the MT2 melatonin receptor in ischemic-stroke mice. Free Radic Biol Med 52:1634-1647
12. Chuang YC (2010) Mitochondrial dysfunction and oxidative stress in seizure-induced neuronal cell death. Acta Neurol Taiwan 19:3-15
13. Coloma FM, Niles LP (1988) Melatonin enhancement of [3H]-gamma- aminobutyric acid and [3H]muscimol binding in rat brain. Biochem Pharmacol 37:1271-1274
14. Cooper RL, Goldman JM, Vandenbergh JG (1993) Monitoring of estrous cyclicity in the laboratory rodent by vaginal lavage. In: Chapin RE, Heindel JJ (eds) Methods in toxicology: female reproductive toxicology, vol 3. Academic Press, New York, pp 45-56
15. Czuczwar SJ, Frey HH (1986) Effect of morphine and morphine-like analgesics on susceptibility to seizures in mice. Neuropharmacology 25:465-469
16. de Lima E, Jr Soares JM, del Carmen Sanabria GY, Gomes VS, Priel MR, Chada BE, Abrao CE, da GN-M, Amado D (2005) Effects of pinealectomy and the treatment with melatonin on the temporal lobe epilepsy in rats. Brain Res 1043:24-31
17. Debnath S, Kannadasan M, Acharjee A, Santhosh Kumar C, Kumar S (2010) Antioxidant activity of the hydro-alcoholic extract of Erythrina fusca Lour. Bark against the animal models of epilepsy. J Chem Pharm Res 2:379-383
18. Demyttenaere K (2011) Agomelatine: a narrative review. Eur Neuropsychopharmacol 21(Suppl 4):S703-S709
19. Devi PU, Manocha A, Vohora D (2008) Seizures, antiepileptics, antioxidants and oxidative stress: an insight for researchers. Expert Opin Pharmacother 9:3169-3177
20. Dubovsky SL, Warren C (2009) Agomelatine, a melatonin agonist with antidepressant properties. Expert Opin Investig Drugs 18:1533-1540
21. Elkhayat HA, Hassanein SM, Tomoum HY, Abd-Elhamid IA, Asaad T, Elwakkad AS (2010) Melatonin and sleep-related problems in children with intractable epilepsy. Pediatr Neurol 42:249-254
22. Freitas RM, Sousa FC, Vasconcelos SM, Viana GS, Fonteles MM (2004) Pilocarpine-induced status epilepticus in rats: lipid peroxidation level, nitrite formation, GABAergic and glutamatergic receptor alterations in the hippocampus, striatum and frontal cortex. Pharmacol Biochem Behav 78:327-332
23. Galeffi F, Sinnar S, Schwartz-Bloom RD (2000) Diazepam promotes ATP recovery and prevents cytochrome c release in hippocampal slices after in vitro ischemia. J Neurochem 75:1242-1249
24. Golombek DA, Escolar E, Burin LJ, De Brito Sanchez MG, Cardinali DP (1991) Time-dependent melatonin analgesia in mice: inhibition by opiate or benzodiazepine antagonism. Eur J Pharmacol 194:25-30
25. Green LC, Tannenbaum SR, Goldman P (1981) Nitrate synthesis in the germfree and conventional rat. Science 212:56-58
26. Henshall DC, Simon RP (2005) Epilepsy and apoptosis pathways. J Cereb Blood Flow Metab 25:1557-1572
27. Hsieh PF, Hou CW, Yao PW, Wu SP, Peng YF, Shen ML, Lin CH, Chao YY, Chang MH, Jeng KC (2011) Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation. J Neuroinflammation 8:57
28. Huong NT, Matsumoto K, Kasai R, Yamasaki K, Watanabe H (1998) In vitro antioxidant activity of Vietnamese ginseng saponin and its components. Biol Pharm Bull 21:978-981
29. Jain S, Bharal N, Khurana S, Mediratta PK, Sharma KK (2011) Anticonvulsant and antioxidant actions of trimetazidine in pentylenetetrazole- induced kindling model in mice. Naunyn Schmiedebergs Arch Pharmacol 383:385-392
30. Liang LP, Waldbaum S, Rowley S, Huang TT, Day BJ, Patel M (2012) Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin. Neurobiol Dis 45:1068-1076
31. Lima E, Cabral FR, Cavalheiro EA, Naffah-Mazzacoratti MG, Amado D (2011) Melatonin administration after pilocarpine-induced status epilepticus: a new way to prevent or attenuate postlesion epilepsy? Epilepsy Behav 20:607-612
32. Lowry H, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurements with the follin phenol reagent. J Biol Chem 193:265-275
33. Malinska D, Kulawiak B, Kudin AP, Kovacs R, Huchzermeyer C, Kann O, Szewczyk A, Kunz WS (2010) Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation. Biochim Biophys Acta 1797:1163-1170
34. Marangos PJ, Patel J, Hirata F, Sondhein D, Paul SM, Skolnick P, Goodwin FK (1981) Inhibition of diazepam binding by tryptophan derivatives including melatonin and its brain metabolite N-acetyl-5-methoxy kynurenamine. Life Sci 29:259-267
35. Millan MJ, Gobert A, Lejeune F, Dekeyne A, Newman-Tancredi A, Pasteau V, Rivet JM, Cussac D (2003a) The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways. J Pharmacol Exp Ther 306:954-964
36. Millan MJ, Gobert A, Lejeune F, Dekeyne A, Newman-Tancredi A, Pasteau V, Rivet JM, Cussac D (2003b) The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways. J Pharmacol Exp Ther 306:954-964
37. Moezi L, Shafaroodi H, Hojati A, Dehpour AR (2011) The interaction of melatonin and agmatine on pentylenetetrazole-induced seizure threshold in mice. Epilepsy Behav 22:200-206
38. Morley-Fletcher S, Mairesse J, Soumier A, Banasr M, Fagioli F, Gabriel C, Mocaer E, Daszuta A, McEwen B, Nicoletti F, Maccari S (2011) Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats. Psychopharmacology 217:301-313
39. Obradovic DI, Bokonjic DR, Savic MM, Andjelkovic DS, Ugresic ND, Stojilkovic MP (2002) Gaba-benzodiazepine receptor complex in brain oxidative metabolism regulation. Pharmacol Res 46:149-154
40. Pahuja M, Mehla J, Kumar GY (2012) Anticonvulsant and antioxidative activity of hydroalcoholic extract of tuber of Orchis mascula in pentylenetetrazole and maximal electroshock induced seizures in rats. J Ethnopharmacol 142:23-27
41. Palmeira CM, Santos MS, Carvalho AP, Oliveira CR (1993) Membrane lipid peroxidation induces changes in gamma-[3H]aminobutyric acid transport and calcium uptake by synaptosomes. Brain Res 609:117-123
42. Patel M (2004) Mitochondrial dysfunction and oxidative stress: cause and consequence of epileptic seizures. Free Radic Biol Med 37:1951-1962
43. Riazi K, Honar H, Homayoun H, Rashidi N, Dehghani M, Sadeghipour H, Gaskari SA, Dehpour AR (2004) Sex and estrus cycle differences in the modulatory effects of morphine on seizure susceptibility in mice. Epilepsia 45:1035-1042
44. Schwartz-Bloom RD, Sah R (2001) Gamma-aminobutyric acid(A) neurotransmission and cerebral ischemia. J Neurochem 77:353-371
45. Singh S, Hota D, Prakash A, Khanduja KL, Arora SK, Chakrabarti A (2010) Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice. Pharmacol Biochem Behav 94:416-422
46. Tejada S, Roca C, Sureda A, Rial RV, Gamundi A, Esteban S (2006) Antioxidant response analysis in the brain after pilocarpine treatments. Brain Res Bull 69:587-592
47. Tejada S, Sureda A, Roca C, Gamundi A, Esteban S (2007) Antioxidant response and oxidative damage in brain cortex after high dose of pilocarpine. Brain Res Bull 71:372-375
48. Tenn CC, Niles LP (1997) The antidopaminergic action of S-20098 is mediated by benzodiazepine/GABA(A) receptors in the striatum. Brain Res 756:293-296
49. Uberos J, Augustin-Morales MC, Molina CA, Florido J, Narbona E, Munoz-Hoyos A (2011) Normalization of the sleep-wake pattern and melatonin and 6-sulphatoxy-melatonin levels after a therapeutic trial with melatonin in children with severe epilepsy. J Pineal Res 50:192-196
50. Uma DP, Pillai KK, Vohora D (2006) Modulation of pentylenetetrazole- induced seizures and oxidative stress parameters by sodium valproate in the absence and presence of N-acetylcysteine. Fundam Clin Pharmacol 20:247-253
51. Velisek L (2006) Models of chemically-induced acute seizures. In: Pitkänen A, Schwartzkroin PA, Mos SL (eds) Models of seizures and epilepsy. Academic Press, Burlington, pp 127-152
52. Verma S, Sinha R, Kumar P, Amin F, Jain J, Tanwar S (2012) Study of Convolvulus pluricaulis for antioxidant and anticonvulsant activity. Cent Nerv Syst Agents Med Chem 12(1):55-59
53. Yemitan OK, Adeyemi OO (2005) CNS depressant activity of Lecaniodiscus cupanioides. Fitoterapia 76:412-418