Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation

Journal of Neuroinflammation

Volumn 8, Issue , 2011, Pages

  Hsieh, Peiyuan F ^a,b   Hou, Chien Wei ^c   Yao, Pei Wun ^c   Wu, Szu Pei ^c   Peng, Yu Fen ^c   Shen, Mei Lin ^a   Lin, Ching Huei ^a   Chao, Ya Yun ^a   Chang, Ming Hong ^a   Jeng, Kee Ching ^a,c  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL CHI NAN UNIVERSITY   (Taiwan)

^c YUANPEI UNIVERSITY   (Taiwan)

Author keywords

BV 2 cells; COX 2; Kainic acid; Mitogen activated protein kinases; Nitric acid; PC12 cells; Reactive oxygen species; Sesamin; Status epilepticus; Superoxide dismutase; Thiobarbituric acid reactive substances

Indexed keywords

ALPHA TOCOPHEROL; CALCIUM ION; CASPASE 3; CYCLOOXYGENASE 2; KAINIC ACID; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SESAMIN; 1,3 DIOXOLANE DERIVATIVE; ANTIOXIDANT; CYCLOOXYGENASE 2 INHIBITOR; LIGNAN; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CALCIUM TRANSPORT; CELL DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; EPILEPTIC STATE; MALE; MORTALITY; MOUSE; NERVE CELL PLASTICITY; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING; ANIMAL; ANIMAL BEHAVIOR; CELL STRAIN; CELL SURVIVAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; LIPID PEROXIDATION; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; CELL SURVIVAL; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DIOXOLES; ENZYME ACTIVATION; KAINIC ACID; LIGNANS; LIPID PEROXIDATION; MALE; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PC12 CELLS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RHOA GTP-BINDING PROTEIN; STATUS EPILEPTICUS;

EID: 79956275648     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-57     Document Type: Article

References (51)

1. Wasterlain CG, Fujikawa DG, Penix L, Sankar R. Pathophysiological mechanisms of brain damage from status epilepticus. Epilepsia 1993, 34:S37-S53. 10.1111/j.1528-1157.1993.tb05905.x, 8385002.
2. Millikan D, Rice B, Silbergleit R. Emergency treatment of status epilepticus: current thinking. Emerg Med Clin North Am 2009, 27:101-113. 10.1016/j.emc.2008.12.001, 19218022.
3. Rocca WA, Sharbrough FW, Hauser WA, Annegers JF, Schoenberg BS. Risk factors for complex partial seizures: a population-based case-control study. Ann Neurol 1987, 21:22-31. 10.1002/ana.410210106, 3827212.
4. Lee B, Cao R, Choi YS, Cho HY, Rhee AD, Hah CK, Hoyt KR, Obrietan K. The CREB/CRE transcriptional pathway: protection against oxidative stress-mediated neuronal cell death. J Neurochem 2009, 108:1251-1265. 10.1111/j.1471-4159.2008.05864.x, 2884273, 19141071.
5. Penner MR, Pinaud R, Robertson HA. Rapid kindling of the hippocampus protects against neural damage resulting from status epilepticus. Neuroreport 2001, 12:453-457. 10.1097/00001756-200103050-00007, 11234745.
6. Turski L, Ikonomidou C, Turski WA, Bortolotto ZA, Cavalheiro EA. Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy. Synapse 1989, 3:154-171. 10.1002/syn.890030207, 2648633.
7. Wang Q, Yu S, Simonyi A, Rottinghaus G, Sun GY, Sun AY. Resveratrol protects against neurotoxicity induced by kainic acid. Neurochem Res 2004, 29:2105-2112. 10.1007/s11064-004-6883-z, 15662844.
8. Muller-Schwarze AB, Tandon P, Liu Z, Yang Y, Holmes GL, Stafstrom CE. Ketogenic diet reduces spontaneous seizures and mossy fiber sprouting in the kainic acid model. Neuroreport 1999, 10:1517-1522. 10.1097/00001756-199905140-00023, 10380973.
9. Wasterlain CG, Shirasaka Y, Mazarati AM, Spigelman I. Chronic epilepsy with damage restricted to the hippocampus: possible mechanisms. Epilepsy Res 1996, 26:255-265. 10.1016/S0920-1211(96)00058-7, 8985705.
10. Gupta YK, Briyal S, Chaudhary G. Protective effect of trans-resveratrol gainst kainic acid-induced seizures and oxidative stress in rats. Pharmacol Biochem Behav 2002, 71:245-249. 10.1016/S0091-3057(01)00663-3, 11812529.
11. Miyamoto R, Shimakawa S, Suzuki S, Ogihara T, Tamai H. Edaravone prevents kainic acid-induced neuronal death. Brain Res 2008, 1209:85-91.
12. Freitas RM, Sousa FC, Vasconcelos SM, Viana GS, Fonteles MM. Pilocarpine-induced status epilepticus in rats: lipid peroxidation level, nitrite formation, GABAergic and glutamatergic receptor alterations in the hippocampus, striatum and frontal cortex. Pharmacol Biochem Behav 2004, 78:327-332. 10.1016/j.pbb.2004.04.004, 15219774.
13. Bashkatova V, Narkevich V, Vitskova G, Vanin A. The influence of anticonvulsant and antioxidant drugs on nitric oxide level and lipid peroxidation in the rat brain during penthylenetetrazole-induced epileptiform model seizures. Prog Neuropsychopharmacol Biol Psychiatry 2003, 27:487-492. 10.1016/S0278-5846(03)00037-X, 12691785.
14. Meyerhoff JL, Lee JK, Rittase BW, Tsang AY, Yourick DL. Lipoic acid pretreatment attenuates ferric chloride-induced seizures in the rat. Brain Res 2004, 1016:139-144. 10.1016/j.brainres.2004.03.019, 15246849.
15. Sun AY, Cheng Y, Bu Q, Oldfield F. The biochemical mechanism of the excitotoxicity of kainic acid. Mol Chem Neuropathol 1992, 17:51-63. 10.1007/BF03159981, 1326973.
16. Bruce AJ, Baudry M. Oxygen free radicals in rat limbic structures after kainate-induced seizures. Free Radical Biol Med 1995, 18:993-1002.
17. D'Antuono M, Benini R, Biagini G, D'Arcangelo G, Barbarosie M, Tancredi V, Avoli M. Limbic network interactions leading to hyperexcitability in a model of temporal lobe epilepsy. J Neurophysiol 2002, 87:634-639.
18. Arispe N, Pollard HB, Rojas E. β-Amyloid Ca2+ -channel hypothesis for neuronal death in Alzheimer disease. Mol Cell Biochem 1994, 140:119-125. 10.1007/BF00926750, 7898484.
19. Goodenough S, Davidson M, Chen M, Beckmann A, Pujic Z, Otsuki M, Matsumoto I. Immediate early gene expression and delayed cell death in limbic areas of the rat brain after kainic acid treatment and recovery in the cold. Exp Neurol 1997, 145:451-461. 10.1006/exnr.1997.6471, 9217081.
20. Dubreuil CI, Marklund N, Deschamps K, McIntosh TK, McKerracher L. Activation of Rho after traumatic brain injury and seizure in rats. Exp Neurol 2006, 198:361-369. 10.1016/j.expneurol.2005.12.002, 16448651.
21. Matagne V, Lebrethon MC, Gérard A, Bourguignon JP. Kainate/estrogen receptor involvement in rapid estradiol effects in vitro and intracellular signaling pathways. Endocrinology 2005, 146:2313-2323. 10.1210/en.2004-1265, 15661860.
22. Hou RC, Chen HL, Tzen JT, Jeng KC. Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells. Neuroreport 2003, 14:1815-1819. 10.1097/00001756-200310060-00011, 14534426.
23. Lahaie-Collins V, Bournival J, Plouffe M, Carange J, Martinoli MG. Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergic cells under MPP-induced oxidative stress. Oxid Med Cell Longev 2008, 1:54-62. 10.4161/oxim.1.1.6958, 2715194, 19794909.
24. Ma CJ, Kim SR, Kim J, Kim YC. Meso-dihydroguaiaretic acid and licarin A of Machilus thunbergii protect against glutamate-induced toxicity in primary cultures of a rat cortical cells. Br J Pharmacol 2005, 146:752-759. 10.1038/sj.bjp.0706380, 1751201, 16151440.
25. Kanada A, Nishimura Y, Yamaguchi JY, Kobayashi M, Mishima K, Horimoto K, Kanemaru K, Oyama Y. Extract of Ginkgo biloba leaves attenuates kainate-induced increase in intracellular Ca2+ concentration of rat cerebellar granule neurons. Biol Pharm Bull 2005, 28:934-936. 10.1248/bpb.28.934, 15863911.
26. Fukumoto LR, Mazza G. Assessing antioxidant and prooxidant activities and phenolic compounds. J Agric Food Chem 2000, 48:3597-3604. 10.1021/jf000220w, 10956156.
27. Hou RC, Huang HM, Tzen JT, Jeng KC. Protective effects of sesamin and sesamolin on hypoxic neuronal and PC12 cells. J Neurosci Res 2003, 74:123-133. 10.1002/jnr.10749, 13130514.
28. Jeng KC, Hou RC, Wang JC, Ping LI. Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB. Immunol Lett 2005, 97:101-106. 10.1016/j.imlet.2004.10.004, 15626481.
29. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358. 10.1016/0003-2697(79)90738-3, 36810.
30. Racine RJ. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol 1972, 32:281-294. 10.1016/0013-4694(72)90177-0, 4110397.
31. Handforth A, Ackermann RF. Functional 14 C 2-deoxyglucose mapping of progressive states of status epilepticus induced by amygdala stimulation in rat. Brain Res 1988, 460:94-102. 10.1016/0006-8993(88)90433-7, 3219574.
32. Wu WH, Kang YP, Wang NH, Jou HJ, Wang TA. Sesame ingestion affects sex hormones, antioxidant status, and blood lipids in postmenopausal women. J Nutr 2006, 136:1270-1275.
33. Dykens JA, Stern A, Trenkner E. Mechanisms of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury. J Neurochem 1987, 49:1222-1228. 10.1111/j.1471-4159.1987.tb10014.x, 3040909.
34. Jamarkattel-Pandit N, Pandit NR, Kim MY, Park SH, Kim KS, Choi H, Kim H, Bu Y. Neuroprotective effect of defatted sesame seeds extract against in vitro and in vivo ischemic neuronal damage. Planta Med 2010, 76:20-26. 10.1055/s-0029-1185903, 19598078.
35. Somera-Molina KC, Nair S, Van Eldik LJ, Watterson DM, Wainwright MS. Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a 'two-hit' seizure model. Brain Res 2009, 1282:162-172. 2739829, 19501063.
36. Hashimoto K, Watanabe K, Nishimura T, Iyo M, Shirayama Y, Minabe Y. Behavioral changes and expression of heat shock protein HSP-70 mRNA, brain-derived neurotrophic factor mRNA, and cyclooxygenase-2 mRNA in rat brain following seizures induced by systemic administration of kainic acid. Brain Res 1998, 804:212-223. 10.1016/S0006-8993(98)00708-2, 9757041.
37. Sandhya TL, Ong WY, Horrocks LA, Farooqui AA. A light and electron microscopic study of cytoplasmic phospholipase A2 and cyclooxygenase-2 in the hippocampus after kainite lesions. Brain Res 1998, 788:223-231. 10.1016/S0006-8993(97)01552-7, 9555027.
38. Sanz O, Estrada A, Ferrer I, Planas AM. Differential cellular distribution and dynamics of HSP70, cyclooxygenase-2, and c-Fos in the rat brain after transient focal ischemia or kainic acid. Neurosci 1997, 80:221-232.
39. Candelario-Jalil E, Ajamieh HH, Sam S, Martinez G, Leon OS. Nimesulide limits kainate-induced oxidative damage in the rat hippocampus. Eur J Pharmacol 2000, 390:295-298. 10.1016/S0014-2999(99)00908-5, 10708736.
40. Sarker KP, Nakata M, Kitajima I, Nakajima T, Maruyama I. Inhibition of caspase-3 activation by SB 203580, p38 mitogen-activated protein kinase inhibitor in nitric oxide-induced apoptosis of PC-12 cells. J Mol Neurosci 15:243-250.
41. Cai C, Li J, Wu Q, Min C, Ouyang M, Zheng S, Ma W, Lin F. Modulation of the oxidative stress and nuclear factor kappaB activation by theaflavin 3,3'-gallate in the rats exposed to cerebral ischemia-reperfusion. Folia Biol 2007, 53:164-172.
42. Xu K, Janet L, Stringer JL. Antioxidants and free radical scavengers do not consistently delay seizure onset in animal models of acute seizures. Epilepsy & Behavior 2008, 13:77-82. 10.1016/j.yebeh.2008.03.002, 21623030.
43. Turski L, Ikonomidou C, Turski WA, Bortolotto ZA, Cavalheiro EA. Cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy. Synapse 1989, 3:154-171. 10.1002/syn.890030207, 2648633.
44. Ayyildiz M, Yildirim M, Agar E. The effects of vitamin E on penicillin-induced epileptiform activity in rats. Exp Brain Res 2006, 174:109-113. 10.1007/s00221-006-0425-7, 16604321.
45. Milatovic D, Gupta RC, Dettbarn WD. Involvement of nitric oxide in kainic acid-induced excitotoxicity in rat brain. Brain Res 2002, 957:330-337. 10.1016/S0006-8993(02)03669-7, 12445975.
46. Tome AR, Feng D, Freitas RM. The effects of alpha-tocopherol on hippocampal oxidative stress prior to in pilocarpine-induced seizures. Neurochem Res 2010, 35:580-587. 10.1007/s11064-009-0102-x, 19941068.
47. Champney TH, Champney JA. Novel anticonvulsant action of chronic melatonin in gerbils. Neuroreport 1992, 3:1152-1154. 10.1097/00001756-199212000-00031, 1493230.
48. Yamamoto HA, Mohanan PV. Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice. Brain Res 2003, 964:100-106. 10.1016/S0006-8993(02)04083-0, 12573517.
49. Wu Z, Xu Q, Zhang L, Kong D, Ma R, Wang L. Protective effect of resveratrol against kainate-induced temporal lobe epilepsy in rats. Neurochem Res 2009, 34:1393-1400. 10.1007/s11064-009-9920-0, 19219549.
50. Shin EJ, Jeong JH, Kim AY, Koh YH, Nah SY, Kim WK, Ko KH, Kim HJ, Wie MB, Kwon YS, Yoneda Y, Kim HC. Protection against kainate neurotoxicity by ginsenosides: attenuation of convulsive behavior, mitochondrial dysfunction, and oxidative stress. J Neurosci Res 2009, 87:710-722. 10.1002/jnr.21880, 18816793.
51. Miyamoto R, Shimakawa S, Suzuki S, Ogihara T, Tamai H. Edaravone prevents kainic acid-induced neuronal death. Brain Res 2008, 1209:85-91.