The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transporters

Journal of Neuroscience Research

Volumn 88, Issue 11, 2010, Pages 2420-2430

  Carmans, Sofie ^a   Hendriks, Jerome J A ^a   Thewissen, Kristof ^a   Van Den Eynden, Jimmy ^a   Stinissen, Piet ^a   Rigo, Jean Michel ^a   Hellings, Niels ^a  

^a NONE

Author keywords

Glycine; Macrophage; Multiple sclerosis; Neuroinflammation; Neutral amino acid transporter

Indexed keywords

2 AMINO 2 METHYLPROPIONIC ACID; AMINO ACID TRANSPORTER; GLYCINE; GLYCINE RECEPTOR; GLYCINE RECEPTOR ANTAGONIST; GLYCINE TRANSPORTER; MYELIN; N [3 (4 FLUOROPHENYL) 3 (4 PHENYLPHENOXY)PROPYL]SARCOSINE; NEUROTRANSMITTER; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; STRYCHNINE; TUMOR NECROSIS FACTOR ALPHA; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; AMINO ACID RECEPTOR AFFECTING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; IMMUNOLOGICAL PROCEDURES; INFLAMMATION; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; ANIMAL; BIOSYNTHESIS; BIOTRANSFORMATION; CELL PROLIFERATION; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; MALE; METABOLISM; MULTIPLE SCLEROSIS; MYELIN SHEATH; PATHOLOGY; PERITONEUM MACROPHAGE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT;

AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; BIOTRANSFORMATION; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCENT ANTIBODY TECHNIQUE; GLYCINE; GLYCINE AGENTS; INFLAMMATION; MACROPHAGES, PERITONEAL; MALE; MULTIPLE SCLEROSIS; MYELIN SHEATH; NEUROTRANSMITTER AGENTS; NITRIC OXIDE; PHAGOCYTOSIS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTORS, GLYCINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRYCHNINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77955387545     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22395     Document Type: Article

References (50)

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