Whole-body and microscopic autoradiography to determine tissue distribution of biopharmaceuticals - Target discoveries with receptor micro-autoradiography engendered new concepts and therapies for vitamin D

Advanced Drug Delivery Reviews

Volumn 65, Issue 8, 2013, Pages 1086-1097

  Stumpf, Walter E ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Drug homunculus; Drug localization; Estradiol; Imaging; Receptor microscopic autoradiography; Vitamin D

Indexed keywords

DRUG HOMUNCULUS; DRUG LOCALIZATION; ESTRADIOL; RECEPTOR MICROSCOPIC AUTORADIOGRAPHY; VITAMIN-D;

BINDING SITES; DEPOSITION; IMAGING TECHNIQUES; TISSUE; VITAMINS;

RADIOGRAPHY;

CALCIFEDIOL; CALCITRIOL; ESTRADIOL; SECALCIFEROL; VITAMIN D; VITAMIN D RECEPTOR;

ARTIFACT; AUTORADIOGRAPHY; BINDING SITE; CELLULAR DISTRIBUTION; DIGESTIVE SYSTEM; DRUG DISTRIBUTION; FALSE NEGATIVE RESULT; FREEZE DRYING; FROZEN SECTION; IMAGE QUALITY; IMMUNOCYTOCHEMISTRY; ISOTOPE LABELING; MICROSCOPIC AUTORADIOGRAPHY; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; REVIEW; TISSUE DISTRIBUTION; TISSUE SLICE; WHOLE BODY AUTORADIOGRAPHY;

EID: 84881025837     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2012.11.008     Document Type: Review

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