Modelling and simulation of continuous L (+) lactic acid production from sugarcane juice in membrane integrated hybrid-reactor system

Biochemical Engineering Journal

Volumn 79, Issue , 2013, Pages 15-24

  Dey, P ^a   Pal, P ^a  

^a NATIONAL INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Lactic acid; Membrane bioreactors; Modelling; Production kinetics; Scale up

Indexed keywords

CORRELATION COEFFICIENT; DOWNSTREAM PURIFICATIONS; L(+)LACTIC ACID PRODUCTION; MEMBRANE BIOREACTOR; MODELLING AND SIMULATIONS; PRODUCTION KINETICS; RENEWABLE CARBON SOURCES; SCALE-UP;

MODELS; NANOFILTRATION; PURIFICATION; SUGAR CANE;

LACTIC ACID;

FRUCTOSE; GLUCOSE; LACTIC ACID; SUCROSE; SUGAR;

ARTICLE; BACTERIAL GROWTH; BIOMASS PRODUCTION; BIOREACTOR; CARBON SOURCE; CELL RECYCLE REACTOR; CONTINUOUS PROCESS; CROSSFLOW FILTRATION; GROWTH; MATHEMATICAL MODEL; MEMBRANE FILTER; MEMBRANE INTEGRATED HYBRID REACTOR SYSTEM; MEMBRANE RESISTANCE; MICROFILTRATION; NANOFILTRATION; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PURIFICATION; SCALE UP; SEPARATION TECHNIQUE; SUGAR INTAKE; SUGAR TRANSPORT; SUGARCANE;

EID: 84880995775     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2013.06.014     Document Type: Article

References (27)

1. Giorno L., Chojnacka K., Donato L., Drioli E. Study of a cell-recycle membrane fermentor for the production of lactic acid by Lactobacillus bulgaricus. Ind. Eng. Chem. Res. 2002, 41:433-440.
2. Gonzalez M.I., Alvarez S., Riera F.A., Alvarez R. Lactic acid recovery from whey ultra filtrate fermentation broths and artificial solutions by nanofiltration. Desalination 2008, 228:84-96.
3. Uribe B.C., Vela M.C.V., Blanco S.A., Miranda M.I.A., Costa E.S. Nanofiltration of sweet whey and prediction of lactose retention as a function of permeate flux using the Kedem-Spiegler and Donnan steric portioning models. Sep. Purif. Technol. 2007, 56:38-46.
4. Tejayadi S, Cheryan M. Lactic acid from cheese whey permeates productivity and economics of a continuous membrane bioreactor. Appl. Microbiol. Biotechnol. 1995, 43:242-248.
5. Jeantet R., Maubois J.L. Semi continuous production of lactic acid in a bioreactor coupled with nanofiltration membranes. Enzyme Microbial Technol. 1996, 16:614-619.
6. Duke M.C., Limb A., Luz S.C. Lactic acid enrichment with inorganic nanofiltration and molecular sieving membranes by pervaporation. Food Bioprod. Process. 2008, 864:290-295.
7. Pal P., Sikder J., Roy S., Giorno L. Process intensification in lactic acid production: a review of membrane based processes. Chem. Eng. Process. 2009, 48:1549-1559.
8. Dey P., Pal P. Direct production of L(+) lactic acid in a continuous and fully membrane-integrated hybrid reactor system under non-neutralizing conditions. J. Membr. Sci. 2012, 389:355-362.
9. Gadjil C.J., Venkatesh K.V. Structured model for batch culture growth of Lactobacillus bulgaricus. J. Chem. Technol. Biotechnol. 1997, 68:89-93.
10. Ludeking R., Piret E.L. A kinetic study of the lactic acid fermentation. J. Biochem. Microbiol. 1959, 1:393-412.
11. Boonmee M., Leksawasdi N., Bridge W., Rogers P.L. Batch and continuous culture of Lactococcuslatis NZ133: experimental data and model development. Biochem. Eng. J. 2003, 14:127-135.
12. Charalampopoulos D., Vazquez J.A., Pandiella S.S. Modelling and validation of Lactobacillus plantarum fermentations in cereal-based media with different sugar concentrations and buffering capacities. Biochem. Eng. J. 2009, 44:96-105.
13. Nandasana A.D., Kumar S. Kinetic modelling of lactic acid production from molasses using Enterococcus faecalis RKY1. Biochem. Eng. J. 2008, 38:277-284.
14. Amrane A., Prigent Y. Analysis of growth and production coupling for batch cultures of Lactobacillus helveticus with the help of an unstructured model. Process Biochem. 1999, 34:1-10.
15. Bouguettoucha A., Balannec B., Amrane A. Unstructured generalized models for the analysis of the inhibitory and the nutritional limitation effects on Lactobacillus helveticus growth: models validation. Biochem. Eng. J. 2008, 39:566-574.
16. Bouguettoucha A., Balannec B., Nacef S., Amrane A. A generalised unstructured model for batch cultures of Lactobacillus helveticus. Enzyme Microbial Technol. 2007, 41:377-382.
17. Nancib D. Lactic acid production by Lactobacillus casei subsp. Rhamnosus growing on date juice: batch, fed-batch and continuous culture kinetics and optimization 2007, University of Nancy, Nancy, France, (thesis).
18. Altiok D., Tokatli F., Harsa S. Kinetic modelling of lactic acid production from whey by Lactobacillus casei (NRRL B-441). J. Chem. Technol. Biotechnol. 2006, 81:1190-1197.
19. Kwon S., Yoo I.K., Lee W.G., Chang H.N. High-rate continuous production of lactic acid by Lactobacillus rhamnosus in a two-stage membrane cell-recycle bioreactor. Biotechnol. Bioeng. 2001, 73:25-34.
20. Nishiwaki A., Dunn I.J. Performance of a two-stage fermenter with cell recycle for continuous production of lactic acid. Bioprocess. Eng. 1999, 21:299-305.
21. Bouguettoucha A., Nacef S., Balannec B., Amrane A. Unstructured models for growth and lactic acid production during two-stage continuous cultures of Lactobacillus helveticus. Process Biochem. 2009, 44:742-748.
22. Chang H.N., Kim N., Kang J., Jeong C.M., Choi J., Fei Q., Kim B.J., Kwon S., Lee S.Y., Kim J. Multi-stage high cell continuous fermentation for high productivity and titer. Bioprocess. Biosyst. Eng. 2011, 34:419-431.
23. Dey P., Sikder J., Roy S., Pal P. Fermentative lactic acid production from a renewable carbon source under response surface optimized conditions without alkali addition: a membrane-based green approach. Clean Technol. Environ. Policy 2012, 14(5):150-159.
24. Yamashita F.Y., Kokugan T. An improved model for cross-flow microfiltration properties of lactic acid fermentation broth. J. Chem. Eng. Jpn. 2010, 43:993-997.
25. Dey P., Linnanen L., Pal P. Separation of lactic acid from fermentation broth by cross flow nanofiltration: membrane characterization and transport modelling. Desalination 2012, 288:47-57.
26. Hofvendahl K., Hagerdal B.H. Factors affecting the fermentative lactic acid production from renewable resources. Enzyme Microbial Technol. 2000, 26:87-107.
27. Lee S.M., Jung J.Y., Chumgn Y.C. Novel method for enhancing permeate flux of submerged membrane system in two phase anaerobic reactor. Water Res. 2001, 35:471-477.