-
1
-
-
0031439247
-
Cellular functions regulated by Src family kinases
-
Thomas SM, Brugge JS, (1997) Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 13: 513-609.
-
(1997)
Annu Rev Cell Dev Biol
, vol.13
, pp. 513-609
-
-
Thomas, S.M.1
Brugge, J.S.2
-
2
-
-
77957937844
-
Targeting SRC in glioblastoma tumors and brain metastases: rationale and preclinical studies
-
Ahluwalia MS, de Groot J, Liu WM, Gladson CL, (2010) Targeting SRC in glioblastoma tumors and brain metastases: rationale and preclinical studies. Cancer Lett 298: 139-149.
-
(2010)
Cancer Lett
, vol.298
, pp. 139-149
-
-
Ahluwalia, M.S.1
de Groot, J.2
Liu, W.M.3
Gladson, C.L.4
-
3
-
-
79960068715
-
From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond
-
Kharas MG, Daley GQ, (2010) From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond. Genes Cancer 1: 1164-1169.
-
(2010)
Genes Cancer
, vol.1
, pp. 1164-1169
-
-
Kharas, M.G.1
Daley, G.Q.2
-
4
-
-
0038386613
-
Src family kinases in tumor progression and metastasis
-
Summy JM, Gallick GE, (2003) Src family kinases in tumor progression and metastasis. Cancer Metastasis Rev 22: 337-358.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 337-358
-
-
Summy, J.M.1
Gallick, G.E.2
-
5
-
-
84873742727
-
Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor
-
Lida M, Brand TM, Campbell DA, Li C, Wheeler DL, (2013) Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor. Oncogene 32: 759-767.
-
(2013)
Oncogene
, vol.32
, pp. 759-767
-
-
Lida, M.1
Brand, T.M.2
Campbell, D.A.3
Li, C.4
Wheeler, D.L.5
-
6
-
-
0141994778
-
The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged
-
Ding Q, Stewart J Jr, Olman MA, Klobe MR, Gladson CL, (2003) The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged. J Biol Chem 278: 39882-39891.
-
(2003)
J Biol Chem
, vol.278
, pp. 39882-39891
-
-
Ding, Q.1
Stewart Jr., J.2
Olman, M.A.3
Klobe, M.R.4
Gladson, C.L.5
-
7
-
-
79955632219
-
Differential transformation capacity of Src family kinases during the initiation of prostate cancer
-
Cai H, Smith DA, Memarzadeh S, Lowell CA, Cooper JA, et al. (2011) Differential transformation capacity of Src family kinases during the initiation of prostate cancer. Proc Natl Acad Sci U S A 108: 6579-6584.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 6579-6584
-
-
Cai, H.1
Smith, D.A.2
Memarzadeh, S.3
Lowell, C.A.4
Cooper, J.A.5
-
8
-
-
70149112112
-
Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients
-
Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, et al. (2009) Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Res 69: 6889-6898.
-
(2009)
Cancer Res
, vol.69
, pp. 6889-6898
-
-
Lu, K.V.1
Zhu, S.2
Cvrljevic, A.3
Huang, T.T.4
Sarkaria, S.5
-
9
-
-
0037483090
-
The SH4-Unique-SH3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src
-
Summy JM, Qian Y, Jiang BH, Guappone-Koay A, Gatesman A, et al. (2003) The SH4-Unique-SH3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src. J Cell Sci 116: 2585-2598.
-
(2003)
J Cell Sci
, vol.116
, pp. 2585-2598
-
-
Summy, J.M.1
Qian, Y.2
Jiang, B.H.3
Guappone-Koay, A.4
Gatesman, A.5
-
10
-
-
60849137218
-
Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma
-
Milano V, Piao Y, LaFortune T, de Groot J, (2009) Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma. Mol Cancer Ther 8: 394-406.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 394-406
-
-
Milano, V.1
Piao, Y.2
LaFortune, T.3
de Groot, J.4
-
11
-
-
77953383616
-
Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors
-
Wu Z, Chang PC, Yang JC, Chu CY, Wang LY, et al. (2010) Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors. Genes Cancer 1: 40-49.
-
(2010)
Genes Cancer
, vol.1
, pp. 40-49
-
-
Wu, Z.1
Chang, P.C.2
Yang, J.C.3
Chu, C.Y.4
Wang, L.Y.5
-
12
-
-
84255169600
-
Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling
-
Sandilands E, Serrels B, McEwan DG, Morton JP, Macagno JP, et al. (2012) Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling. Nat Cell Biol 14: 51-60.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 51-60
-
-
Sandilands, E.1
Serrels, B.2
McEwan, D.G.3
Morton, J.P.4
Macagno, J.P.5
-
13
-
-
64949147229
-
Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients
-
Samanta AK, Chakraborty SN, Wang Y, Kantarjian H, Sun X, et al. (2009) Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients. Oncogene 28: 1669-1681.
-
(2009)
Oncogene
, vol.28
, pp. 1669-1681
-
-
Samanta, A.K.1
Chakraborty, S.N.2
Wang, Y.3
Kantarjian, H.4
Sun, X.5
-
14
-
-
0037438640
-
BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571
-
Donato NJ, Wu JY, Stapley J, Gallick G, Lin H, et al. (2003) BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571. Blood 101: 690-698.
-
(2003)
Blood
, vol.101
, pp. 690-698
-
-
Donato, N.J.1
Wu, J.Y.2
Stapley, J.3
Gallick, G.4
Lin, H.5
-
15
-
-
41349089065
-
A critical role for Lyn in acute myeloid leukemia
-
Dos Santos C, Demur C, Bardet V, Prade-Houdellier N, Payrastre B, et al. (2008) A critical role for Lyn in acute myeloid leukemia. Blood 111: 2269-2279.
-
(2008)
Blood
, vol.111
, pp. 2269-2279
-
-
Dos Santos, C.1
Demur, C.2
Bardet, V.3
Prade-Houdellier, N.4
Payrastre, B.5
-
16
-
-
57149098598
-
Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression
-
Mahon FX, Hayette S, Lagarde V, Belloc F, Turcq B, et al. (2008) Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression. Cancer Res 68: 9809-9816.
-
(2008)
Cancer Res
, vol.68
, pp. 9809-9816
-
-
Mahon, F.X.1
Hayette, S.2
Lagarde, V.3
Belloc, F.4
Turcq, B.5
-
17
-
-
21344470873
-
Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells
-
Stettner MR, Wang W, Nabors LB, Bharara S, Flynn DC, et al. (2005) Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells. Cancer Res 65: 5535-5543.
-
(2005)
Cancer Res
, vol.65
, pp. 5535-5543
-
-
Stettner, M.R.1
Wang, W.2
Nabors, L.B.3
Bharara, S.4
Flynn, D.C.5
-
18
-
-
77950284093
-
LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer
-
Choi YL, Bocanegra M, Kwon MJ, Shin YK, Nam SJ, et al. (2010) LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer. Cancer Res 70: 2296-2306.
-
(2010)
Cancer Res
, vol.70
, pp. 2296-2306
-
-
Choi, Y.L.1
Bocanegra, M.2
Kwon, M.J.3
Shin, Y.K.4
Nam, S.J.5
-
19
-
-
51049114726
-
Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma
-
Guan H, Zhou Z, Gallick GE, Jia SF, Morales J, et al. (2008) Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma. Mol Cancer Ther 7: 1807-1816.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1807-1816
-
-
Guan, H.1
Zhou, Z.2
Gallick, G.E.3
Jia, S.F.4
Morales, J.5
-
20
-
-
0030927381
-
Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice
-
Weissenberger J, Steinbach JP, Malin G, Spada S, Rulicke T, et al. (1997) Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice. Oncogene 14: 2005-2013.
-
(1997)
Oncogene
, vol.14
, pp. 2005-2013
-
-
Weissenberger, J.1
Steinbach, J.P.2
Malin, G.3
Spada, S.4
Rulicke, T.5
-
21
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, et al. (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17: 98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
-
22
-
-
79951847989
-
Principles and current strategies for targeting autophagy for cancer treatment
-
Amaravadi RK, Lippincott-Schwartz J, Yin XM, Weiss WA, Takebe N, et al. (2011) Principles and current strategies for targeting autophagy for cancer treatment. Clin Cancer Res 17: 654-666.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 654-666
-
-
Amaravadi, R.K.1
Lippincott-Schwartz, J.2
Yin, X.M.3
Weiss, W.A.4
Takebe, N.5
-
23
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, et al. (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4: 151-175.
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
-
24
-
-
37449034854
-
Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, et al. (2007) Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci U S A 104: 19345-19350.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19345-19350
-
-
DeBerardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
-
25
-
-
84857792910
-
Breathless cancer cells get fat on glutamine
-
Anastasiou D, Cantley LC, (2012) Breathless cancer cells get fat on glutamine. Cell Res 22: 443-446.
-
(2012)
Cell Res
, vol.22
, pp. 443-446
-
-
Anastasiou, D.1
Cantley, L.C.2
-
26
-
-
34547134691
-
Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice
-
Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, et al. (2007) Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice. Clin Cancer Res 13: 4051-60.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4051-4060
-
-
Gondi, C.S.1
Lakka, S.S.2
Dinh, D.H.3
Olivero, W.C.4
Gujrati, M.5
-
27
-
-
79955932525
-
Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity
-
Wang D, Olman MA, Stewart J Jr, Tipps R, Huang P, et al. (2011) Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity. PLoS One 6: e19629.
-
(2011)
PLoS One
, vol.6
-
-
Wang, D.1
Olman, M.A.2
Stewart Jr., J.3
Tipps, R.4
Huang, P.5
-
28
-
-
59049087460
-
Bidirectional transport of amino acids regulates mTOR and autophagy
-
Nicklin P, Bergman P, Zhang B, Triantafellow E, Wang H, et al. (2009) Bidirectional transport of amino acids regulates mTOR and autophagy. Cell 136: 521-534.
-
(2009)
Cell
, vol.136
, pp. 521-534
-
-
Nicklin, P.1
Bergman, P.2
Zhang, B.3
Triantafellow, E.4
Wang, H.5
-
29
-
-
79953757100
-
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3
-
Guryanova OA, Wu Q, Cheng L, Lathia JD, Huang Z, et al. (2011) Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. Cancer Cell 19: 498-511.
-
(2011)
Cancer Cell
, vol.19
, pp. 498-511
-
-
Guryanova, O.A.1
Wu, Q.2
Cheng, L.3
Lathia, J.D.4
Huang, Z.5
-
30
-
-
58049198191
-
Brain cancer stem cells display preferential sensitivity to Akt inhibition
-
Eyler CE, Foo WC, LaFiura KM, McLendon RE, Hjelmeland AB, et al. (2008) Brain cancer stem cells display preferential sensitivity to Akt inhibition. Stem Cells 26: 3027-3036.
-
(2008)
Stem Cells
, vol.26
, pp. 3027-3036
-
-
Eyler, C.E.1
Foo, W.C.2
LaFiura, K.M.3
McLendon, R.E.4
Hjelmeland, A.B.5
-
31
-
-
0030901234
-
Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells
-
Tilbrook PA, Ingley E, Williams JH, Hibbs ML, Klinken SP, (1997) Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells. EMBO J 16: 1610-1619.
-
(1997)
EMBO J
, vol.16
, pp. 1610-1619
-
-
Tilbrook, P.A.1
Ingley, E.2
Williams, J.H.3
Hibbs, M.L.4
Klinken, S.P.5
-
32
-
-
19444375120
-
Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions
-
Mulky A, Sarafianos SG, Jia Y, Arnold E, Kappes JC, (2005) Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions. J Mol Biol 349: 673-684.
-
(2005)
J Mol Biol
, vol.349
, pp. 673-684
-
-
Mulky, A.1
Sarafianos, S.G.2
Jia, Y.3
Arnold, E.4
Kappes, J.C.5
-
33
-
-
14844327984
-
p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain
-
Ding Q, Grammer JR, Nelson MA, Guan JL, Stewart JE Jr, et al. (2005) p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain. J Biol Chem 280: 6802-6815.
-
(2005)
J Biol Chem
, vol.280
, pp. 6802-6815
-
-
Ding, Q.1
Grammer, J.R.2
Nelson, M.A.3
Guan, J.L.4
Stewart Jr., J.E.5
-
34
-
-
80052225991
-
Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells
-
Mazumdar T, Devecchio J, Agyeman A, Shi T, Houghton JA, (2011) Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells. Cancer Res 71: 5904-5914.
-
(2011)
Cancer Res
, vol.71
, pp. 5904-5914
-
-
Mazumdar, T.1
Devecchio, J.2
Agyeman, A.3
Shi, T.4
Houghton, J.A.5
-
35
-
-
79551540949
-
Hedgehog signaling drives cellular survival in human colon carcinoma cells
-
Mazumdar T, DeVecchio J, Shi T, Jones J, Agyeman A, et al. (2011) Hedgehog signaling drives cellular survival in human colon carcinoma cells. Cancer Res 71: 1092-1102.
-
(2011)
Cancer Res
, vol.71
, pp. 1092-1102
-
-
Mazumdar, T.1
DeVecchio, J.2
Shi, T.3
Jones, J.4
Agyeman, A.5
-
36
-
-
59249105259
-
Monitoring autophagy by electron microscopy in Mammalian cells
-
Yla-Anttila P, Vihinen H, Jokitalo E, Eskelinen EL, (2009) Monitoring autophagy by electron microscopy in Mammalian cells. Methods Enzymol 452: 143-164.
-
(2009)
Methods Enzymol
, vol.452
, pp. 143-164
-
-
Yla-Anttila, P.1
Vihinen, H.2
Jokitalo, E.3
Eskelinen, E.L.4
-
37
-
-
80052338863
-
Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia
-
Kung HN, Marks JR, Chi JT, (2011) Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia. PLoS Genet 7: e1002229.
-
(2011)
PLoS Genet
, vol.7
-
-
Kung, H.N.1
Marks, J.R.2
Chi, J.T.3
-
38
-
-
34047265691
-
Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival
-
Shor AC, Keschman EA, Lee FY, Muro-Cacho C, Letson GD, et al. (2007) Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival. Cancer Res 67: 2800-2808.
-
(2007)
Cancer Res
, vol.67
, pp. 2800-2808
-
-
Shor, A.C.1
Keschman, E.A.2
Lee, F.Y.3
Muro-Cacho, C.4
Letson, G.D.5
-
39
-
-
80053058993
-
Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells
-
Lathia JD, Gallagher J, Myers JT, Li M, Vasanji A, et al. (2011) Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. PLoS One 6: e24807.
-
(2011)
PLoS One
, vol.6
-
-
Lathia, J.D.1
Gallagher, J.2
Myers, J.T.3
Li, M.4
Vasanji, A.5
-
40
-
-
78149475478
-
Akt and autophagy cooperate to promote survival of drug-resistant glioma
-
Fan QW, Cheng C, Hackett C, Feldman M, Houseman BT, et al. (2010) Akt and autophagy cooperate to promote survival of drug-resistant glioma. Sci Signal 3: ra81.
-
(2010)
Sci Signal
, vol.3
-
-
Fan, Q.W.1
Cheng, C.2
Hackett, C.3
Feldman, M.4
Houseman, B.T.5
-
41
-
-
79953331942
-
MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer
-
Majid S, Saini S, Dar AA, Hirata H, Shahryari V, et al. (2011) MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer. Cancer Res 71: 2611-2621.
-
(2011)
Cancer Res
, vol.71
, pp. 2611-2621
-
-
Majid, S.1
Saini, S.2
Dar, A.A.3
Hirata, H.4
Shahryari, V.5
-
42
-
-
77958134349
-
Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia
-
Zimmerman EI, Dollins CM, Crawford M, Grant S, Nana-Sinkam SP, et al. (2010) Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia. Mol Pharmacol 78: 811-817.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 811-817
-
-
Zimmerman, E.I.1
Dollins, C.M.2
Crawford, M.3
Grant, S.4
Nana-Sinkam, S.P.5
-
43
-
-
0035393501
-
A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells
-
Bates RC, Edwards NS, Burns GF, Fisher DE, (2001) A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells. Cancer Res 61: 5275-5283.
-
(2001)
Cancer Res
, vol.61
, pp. 5275-5283
-
-
Bates, R.C.1
Edwards, N.S.2
Burns, G.F.3
Fisher, D.E.4
-
44
-
-
58149399472
-
Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia
-
Trentin L, Frasson M, Donella-Deana A, Frezzato F, Pagano MA, et al. (2008) Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia. Blood 112: 4665-4674.
-
(2008)
Blood
, vol.112
, pp. 4665-4674
-
-
Trentin, L.1
Frasson, M.2
Donella-Deana, A.3
Frezzato, F.4
Pagano, M.A.5
-
45
-
-
80755140037
-
Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells
-
Tibaldi E, Brunati AM, Zonta F, Frezzato F, Gattazzo C, et al. (2011) Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells. Leukemia 25: 1768-1781.
-
(2011)
Leukemia
, vol.25
, pp. 1768-1781
-
-
Tibaldi, E.1
Brunati, A.M.2
Zonta, F.3
Frezzato, F.4
Gattazzo, C.5
-
46
-
-
57649198325
-
Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity
-
Chudakova DA, Zeidan YH, Wheeler BW, Yu J, Novgorodov SA, et al. (2008) Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity. J Biol Chem 283: 28806-28816.
-
(2008)
J Biol Chem
, vol.283
, pp. 28806-28816
-
-
Chudakova, D.A.1
Zeidan, Y.H.2
Wheeler, B.W.3
Yu, J.4
Novgorodov, S.A.5
-
47
-
-
0035964285
-
Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis
-
Grishin AV, Azhipa O, Semenov I, Corey SJ, (2001) Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis. Proc Natl Acad Sci U S A 98: 10172-10177.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10172-10177
-
-
Grishin, A.V.1
Azhipa, O.2
Semenov, I.3
Corey, S.J.4
-
48
-
-
80052749324
-
Retrospective study of dasatinib for recurrent glioblastoma after bevacizumab failure
-
Lu-Emerson C, Norden AD, Drappatz J, Quant EC, Beroukhim R, et al. (2011) Retrospective study of dasatinib for recurrent glioblastoma after bevacizumab failure. J Neurooncol 104: 287-291.
-
(2011)
J Neurooncol
, vol.104
, pp. 287-291
-
-
Lu-Emerson, C.1
Norden, A.D.2
Drappatz, J.3
Quant, E.C.4
Beroukhim, R.5
-
49
-
-
77950986253
-
c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin
-
Xu J, Millard M, Ren X, Cox OT, Erdreich-Epstein A, (2010) c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin. Blood 115: 2709-2718.
-
(2010)
Blood
, vol.115
, pp. 2709-2718
-
-
Xu, J.1
Millard, M.2
Ren, X.3
Cox, O.T.4
Erdreich-Epstein, A.5
-
50
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
Kondo Y, Kanzawa T, Sawaya R, Kondo S, (2005) The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 5: 726-734.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
51
-
-
84864667633
-
Bcl-2:Beclin 1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch
-
Marquez RT, Xu L, (2012) Bcl-2:Beclin 1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch. Am J Cancer Res 2: 214-221.
-
(2012)
Am J Cancer Res
, vol.2
, pp. 214-221
-
-
Marquez, R.T.1
Xu, L.2
-
52
-
-
80051696767
-
Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2
-
Ahn JH, Lee M, (2011) Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2. Cancer Lett 310: 188-197.
-
(2011)
Cancer Lett
, vol.310
, pp. 188-197
-
-
Ahn, J.H.1
Lee, M.2
-
53
-
-
0842347483
-
Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts
-
Goldenberg-Furmanov M, Stein I, Pikarsky E, Rubin H, Kasem S, et al. (2004) Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts. Cancer Res 64: 1058-1066.
-
(2004)
Cancer Res
, vol.64
, pp. 1058-1066
-
-
Goldenberg-Furmanov, M.1
Stein, I.2
Pikarsky, E.3
Rubin, H.4
Kasem, S.5
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