Phospho-GSK-3β is involved in the high-glucose-mediated lipid deposition in renal tubular cells in diabetes

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 9, 2013, Pages 2066-2075

  Liu, Wei ^a   Hao, Jun ^a   Zhu, Lin ^a   Li, Fan ^a   Liu, Qingjuan ^a   Liu, Shuxia ^a   Zhao, Song ^a   Li, Hongbo ^a   Duan, Huijun ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Bad; GSK 3 ; Lipid metabolism; PI3K Akt pathway; SREBP 1

Indexed keywords

GLUCOSE; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; LIPID; PROTEIN BAD; PROTEIN KINASE B; PYRROLOPYRIMIDINE DERIVATIVE; SHORT HAIRPIN RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STREPTOZOCIN; TRIACYLGLYCEROL; TWS 119; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENE TARGETING; GENE VECTOR; GLUCOSE INTAKE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULE CELL; LIPID STORAGE; LIPOGENESIS; LIVER CELL; MEDIATOR; NONHUMAN; PROADIPOCYTE; PROTEIN CONTENT; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; STREPTOZOCIN DIABETES; TRIACYLGLYCEROL BLOOD LEVEL; WILD TYPE;

RATTUS;

BAD; GSK-3Β; LIPID METABOLISM; PI3K/AKT PATHWAY; SREBP-1;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE; HUMANS; KIDNEY TUBULES; LIPID METABOLISM; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSFECTION; TRIGLYCERIDES;

EID: 84880985226     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.07.007     Document Type: Article

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