High-fat diet causes increased serum insulin and glucose which synergistically lead to renal tubular lipid deposition and extracellular matrix accumulation

British Journal of Nutrition

Volumn 107, Issue 1, 2012, Pages 74-85

  Hao, Jun ^a   Liu, Shu Xia ^a   Zhao, Song ^a   Liu, Qing Juan ^a   Liu, Wei ^a   Duan, Hui Jun ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Extracellular matrix accumulation; High fat diet; Lipid accumulation; Sterol regulatory element binding protein 1; Transforming growth factor 1

Indexed keywords

FAT DROPLET; FATTY ACID SYNTHASE; FIBRONECTIN; GLUCOSE; INSULIN; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE SILENCING; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HORMONE ACTION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERTRIGLYCERIDEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE; KIDNEY TUBULE CELL; LIPID DIET; LIPID STORAGE; MALE; METABOLIC SYNDROME X; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CELL LINE; DIETARY FATS; EXTRACELLULAR MATRIX; FATTY ACID SYNTHETASE COMPLEX; FIBRONECTINS; GENE EXPRESSION REGULATION; HUMANS; HYPERGLYCEMIA; HYPERINSULINISM; INSULIN; KIDNEY TUBULES; LIPID METABOLISM; MALE; RANDOM ALLOCATION; RATS; RATS, WISTAR; RENAL INSUFFICIENCY; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA1;

RATTUS NORVEGICUS;

EID: 84862909595     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114511002613     Document Type: Article

References (36)

1. Kendall CW, Josse AR, Esfahani A, et al. (2010) Nuts, metabolic syndrome and diabetes. Br J Nutr 104, 465-473.
2. Watanabe S, Yaginuma R, Ikejima K, et al. (2008) Liver diseases and metabolic syndrome. J Gastroenterol 43, 509-518.
3. Egert S, Bosy-Westphal A, Seiberl J, et al. (2009) Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study. Br J Nutr 102, 1065-1074.
4. Korantzopoulos P, Elisaf M & Milionis HJ (2007) Multifactor-ial intervention in metabolic syndrome targeting at prevention of chronic kidney disease ready for prime time? Nephrol Dial Transplant 22, 2768-2774. (Pubitemid 350093476)
5. Kume S, Uzu T, Araki S, et al. (2007) Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet. J Am Soc Nephrol 18, 2715-2723. (Pubitemid 47531198)
6. Spencer MW, Mühlfeld AS, Segerer S, et al. (2004) Hypergly-cemia and hyperlipidemia act synergistically to induce renal disease in LDL receptor-deficient BALB mice. Am J Nephrol 24, 20-31. (Pubitemid 38250483)
7. Proctor G, Jiang T, Iwahashi M, et al. (2006) Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes. Diabetes 55, 2502-2509. (Pubitemid 44871150)
8. Jiang T, Wang Z, Proctor G, et al. (2005) Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway. J Biol Chem 280, 32317-32325. (Pubitemid 41361841)
9. Li HH, Hsu YH, Wei CC, et al. (2008) Interleukin-20 induced cell death in renal epithelial cells and was associated with acute renal failure. Genes Immun 9, 395-404.
10. Jun H, Song Z, Chen W, et al. (2009) In vivo and in vitro effects of SREBP-1 on diabetic renal tubular lipid accumulation and RNAi-mediated gene silencing study. Histochem Cell Biol 131, 327-345.
11. Lotan D, Sheinberg N, Kopolovic J, et al. (2008) Expression of SDF-1/CXCR4 in injured human kidneys. Pediatr Nephrol 23, 71-77. (Pubitemid 50000093)
12. Sakai J, Duncan EA, Rawson RB, et al. (1996) Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment. Cell 85, 1037-1046. (Pubitemid 26231170)
13. Menendez JA, Vazquez-Martin A, Ortega FJ, et al. (2009) Fatty acid synthase: association with insulin resistance, type 2 diabetes, and cancer. Clin Chem 55, 425-438.
14. Wang XL, Jiang LL, Ma J, et al. (2008) Changes of very long-chain free fatty acids in serum and liver tissues of rats with diabetes induced by high fat food (in Chinese). Chinese Gen Pract 11, 306-308.
15. Racusen LC, Monteil C, Sgrignoli A, et al. (1997) Cell lines with extended in vitro growth potential from human renal proximal tubule: characterization, response to inducers, and comparison with established cell lines. J Lab Clin Med 129, 318-329. (Pubitemid 27169434)
16. Folch J, Lees M & Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226, 497-509.
17. Hsu CL & Yen GC (2007) Effect of gallic acid on high fat diet-induced dyslipidaemia, hepatosteatosis and oxidative stress in rats. Br J Nutr 98, 727-735.
18. Moraes RC, Blondet A, Birkenkamp-Demtroeder K, et al. (2003) Study of the alteration of gene expression in adipose tissue of diet-induced obese mice by microarray and reverse transcription-polymerase chain reaction analyses. Endocrinology 144, 4773-4782. (Pubitemid 37378391)
19. Dobbins RL, Szczepaniak LS, Bentley B, et al. (2001) Prolonged inhibition of muscle carnitine palmitoyltransfer-ase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats. Diabetes 50, 123-130. (Pubitemid 32047990)
20. Afonso RA, Lautt WW, Schafer J, et al. (2010) High-fat diet results in postprandial insulin resistance that involves para-sympathetic dysfunction. Br J Nutr 104, 1450-1459.
21. Bourgoin F, Bachelard H, Badeau M, et al. (2008) Endothelial and vascular dysfunctions and insulin resistance in rats fed a high-fat, high-sucrose diet. Am J Physiol Heart Circ Physiol 295, H1044-H1055.
22. Santoso MI & Rohman MS (2006) Decreased TGF-beta1 and IGF-1 protein expression in rat embryo skull bone in folic acid-restricted diet. J Nutr Biochem 17, 51-56. (Pubitemid 41774406)
23. Kohli R, Kirby M, Xanthakos SA, et al. (2010) High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology 52, 934-944.
24. Carroll JF & Tyagi SC (2005) Extracellular matrix remodeling in the heart of the homocysteinemic obese rabbit. Am J Hypertens 18, 692-698. (Pubitemid 40692438)
25. Lara-Castro C & Garvey WT (2008) Intracellular lipid accumulation in liver and muscle and the insulin resistance syndrome. Endocrinol Metab Clin North Am 37, 841-856.
26. Van der Kallen CJ, Voors-Pette C, Bouwman FG, et al. (2002) Evidence of insulin resistant lipid metabolism in adipose tissue in familial combined hyperlipidemia, but not type 2 diabetes mellitus. Atherosclerosis 164, 337-346. (Pubitemid 35223085)
27. Hoffler U, Hobbie K, Wilson R, et al. (2009) Diet-induced obesity is associated with hyperleptinemia, hyperinsuline-mia, hepatic steatosis, and glomerulopathy in C57Bl/6J mice. Endocrine 36, 311-325.
28. Shimomura I, Bashmakov Y, Ikemoto S, et al. (1999) Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes. Proc Natl Acad Sci USA 96, 13656-13661.
29. Chen G, Liang G, Ou J, et al. (2004) Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Proc Natl Acad Sci USA 101, 11245-11250. (Pubitemid 39038332)
30. Anderson PW, Zhang XY, Tian J, et al. (1996) Insulin and angiotensin II are additive in stimulating TGF-beta 1 and matrix mRNAs in mesangial cells. Kidney Int 50, 745-753. (Pubitemid 26302661)
31. Olsson U, Egnell AC, Lee MR, et al. (2001) Changes in matrix proteoglycans induced by insulin and fatty acids in hepatic cells may contribute to dyslipidemia of insulin resistance. Diabetes 50, 2126-2132. (Pubitemid 33643681)
32. Dekkers BG, Schaafsma D, Tran T, et al. (2009) Insulin-induced laminin expression promotes a hypercontractile airway smooth muscle phenotype. Am J Respir Cell Mol Biol 41, 494-504.
33. Sun L, Halaihel N, Zhang W, et al. (2002) Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus. J Biol Chem 277, 18919-18927. (Pubitemid 34952453)
34. O'Callaghan BL, Koo SH, Wu Y, et al. (2001) Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes. J Biol Chem 276, 16033-16039.
35. Dentin R, Girard J & Postic C (2005) Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver. Biochimie 87, 81-86. (Pubitemid 40298769)
36. Dentin R, Pégorier JP, Benhamed F, et al. (2004) Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression. J Biol Chem 279, 20314-20326. (Pubitemid 38623477)