Identification of resistance of Plasmodium falciparum to artesunate-mefloquine combination in an area along the Thai-Myanmar border: Integration of clinico-parasitological response, systemic drug exposure, and in vitro parasite sensitivity

Malaria Journal

Volumn 12, Issue 1, 2013, Pages

  Na Bangchang, Kesara ^a   Muhamad, Phunuch ^a   Ruaengweerayut, Ronnatrai ^b   Chaijaroenkul, Wanna ^a   Karbwang, Juntra ^c  

^a THAMMASAT UNIVERSITY   (Thailand)

^b MAE SOT GENERAL HOSPITAL   (Thailand)

^c NAGASAKI UNIVERSITY   (Japan)

Author keywords

Artesunate; Drug resistance; in vitro sensitivity; Mefloquine; pfmdr1 copy number; Plasmodium falciparum

Indexed keywords

ARTESUNATE PLUS MEFLOQUINE; DIHYDROARTEMISININ; MEFLOQUINE; MULTIDRUG RESISTANCE PROTEIN 1;

ADOLESCENT; ADULT; ANTIMALARIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; DRUG EXPOSURE; FEMALE; GENE DOSAGE; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MYANMAR; PARASITE ISOLATION; PLASMA CONCENTRATION-TIME CURVE; PLASMODIUM FALCIPARUM; THAILAND;

ADOLESCENT; ADULT; ANTIMALARIALS; ARTEMISININS; DNA, PROTOZOAN; DRUG COMBINATIONS; FEMALE; GENE DOSAGE; HUMANS; MALARIA, FALCIPARUM; MALE; MEFLOQUINE; MIDDLE AGED; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MYANMAR; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; THAILAND; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84880942863     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-12-263     Document Type: Article

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