Characterization of "Yaa Chud" medicine on the Thailand-Myanmar border: Selecting for drug-resistant malaria and threatening public health

American Journal of Tropical Medicine and Hygiene

Volumn 79, Issue 5, 2008, Pages 662-669

  Newton, Paul N ^a,c   Hampton, Christina Y ^b   Alter Hall, Krystyn ^b   Teerwarakulpana, Thanongsak ^d   Prakongpan, Sompol ^e   Ruangveerayuth, Ronnatrai ^f   White, Nicholas J ^c,g   Day, Nicholas P J ^c,g   Tudino, Mabel B ^h   Mancuso, Natalia ^h   Fernández, Facundo M ^b  

^a MAHOSOT HOSPITAL   (Laos)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d Mahidol University ^*

^e MAHIDOL UNIVERSITY   (Thailand)

^f MAE SOT GENERAL HOSPITAL   (Thailand)

^g MAHIDOL UNIVERSITY   (Thailand)

^h Inst de Quim Fis de Materiales   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALPRENOLOL; AMITRIPTYLINE; AMPICILLIN; ANTACID AGENT; ARTEMISININ; ASCORBIC ACID; CHLOROQUINE; CHLORPHENIRAMINE; DICLOFENAC; DIPYRONE; DOXYCYCLINE; INDOMETACIN; NICOTINAMIDE; PARACETAMOL; PRAZEPAM; PREDNISOLONE; PRIMAQUINE; PYRIDOXINE; QUININE; SULFAMETHOXAZOLE; TETRACYCLINE; THIAMINE; TOLPERISONE;

ACIDOSIS; AGRANULOCYTOSIS; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BRADYCARDIA; DISEASE SEVERITY; DROWSINESS; DRUG CAPSULE; DRUG EFFICACY; GASTROINTESTINAL IRRITATION; HEALTH CARE COST; HEMOLYSIS; HUMAN; HYPOGLYCEMIA; MALARIA; MASS SPECTROMETRY; METHEMOGLOBINEMIA; MORBIDITY; MORTALITY; MULTIDRUG RESISTANCE; MYANMAR; NEWBORN HEMOLYTIC DISEASE; PLASMODIUM FALCIPARUM; RASH; STOMACH IRRITATION; TABLET; THAILAND; TINNITUS;

PLASMODIUM FALCIPARUM;

EID: 55849144034     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2008.79.662     Document Type: Article

References (43)

1. Nosten F, van Vugt M, Price R, Luxemburger C, Thway KL, Brockman A, McGready R, ter Kuile F, Looareesuwan S, White NJ, 2000. Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study. Lancet 356: 297-302.
2. Price RN, Nosten F, 2001. Drug resistant falciparum malaria: clinical consequences and strategies for prevention. Drug Resist Updat 4: 187-196.
3. Carrara VI, Sirilak S, Thonglairuam J, Rojanawatsirivet C, Proux S, Gilbos V, Brockman A, Ashley EA, McGready R, Krudsood S, Leemingsawat S, Looareesuwan S, Singhasivanon P, White N, Nosten F, 2006. Deployment of early diagnosis and mefloquine-artesunate treatment of falciparum malaria in Thailand: the Tak Malaria Initiative. PLoS Med 3: e183.
4. White NJ, 1999. Antimalarial drug resistance and combination chemotherapy. Philos Trans R Soc Lond B Biol Sci 354: 739-749.
5. White NJ, 2004. Antimalarial drug resistance. J Clin Invest 113: 1084-1092.
6. Dondorp A, Nosten F, Stepniewska K, Day N, White N, 2005. Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet 366: 717-725.
7. Jaidee S, Limpananon J, Wittayanartpaisal S, 1980. Drug utilization of yaa-chud in Thailand. Thai J Pharm Sci 5: 219-220.
8. Wiwat C, Silapa-archa W, Temsirilerkhul R, Chiowatana J, 1982. Rural self-medication in malaria infection. Thai J Pharm Sci 7: 14-29.
9. Kamolratanakul P, Dhanamun B, Thaithong S, 1992. Human behavior in relation to selection of malaria treatment. Southeast Asian J Trop Med Public Health 23: 189-194.
10. Plasai V, Spielman A, 1996. Mefloquine insusceptibility of malaria in Thailand not promoted by nonregulated drug-use. Acta Trop 60: 281-289.
11. Cunningham CE, 1970. Thai "injection doctors"; antibiotic mediators. Soc Sci Med 4: 1-24.
12. Foster SD, 1991. Pricing, distribution, and use of antimalarial drugs. Bull World Health Organ 69: 349-363.
13. Amin AA, Hughes DA, Marsh V, Abuya TO, Kokwaro GO, Winstanley PA, Ochola SA, Snow RW, 2004. The difference between effectiveness and efficacy of antimalarial drugs in Kenya. Trop Med Int Health 9: 967-974.
14. Basco LK, 2004. Molecular epidemiology of malaria in Cameroon. XIX. Quality of antimalarial drugs used for self-medication. Am J Trop Med Hyg 70: 245-250.
15. Goodman C, Brieger W, Unwin A, Mills A, Meek S, Greer G, 2007. Medicine sellers and malaria treatment in sub-Saharan Africa: what do they do and how can their practice be improved? Am J Trop Med Hyg 77: 203-218.
16. Brown GW, Saunders JP, Singh S, Huxsoll DL, Shirai A, 1978. Single dose doxycycline therapy for scrub typhus. Trans R Soc Trop Med Hyg 72: 412-416.
17. Taylor RB, Shakoor O, Behrens RH, 1995. Drug quality, a contributor to drug-resistance. Lancet 346: 122.
18. Okeke IN, Lamikanra A, Edelman R, 1999. Socioeconomic and behavioral factors leading to acquired bacterial resistance to antibiotics in developing countries. Emerg Infect Dis 5: 18-27.
19. Noranate N, Durand R, Tall A, Marrama L, Spiegel A, Sokhna C, Pradines B, Cojean S, Guillotte M, Bischoff E, Ekala MT, Bouchier C, Fandeur T, Ariey F, Patarapotikul J, Le Bras J, Trape JF, Rogier C, Mercereau-Puijalon O, 2007. Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use. PLoS ONE 2: e139.
20. Yeung S, White NJ, 2005. How do patients use antimalarial drugs? A review of the evidence. Trop Med Int Health 10: 121-138.
21. Kachur SP, Black C, Abdulla S, Goodman C, 2006. Putting the genie back in the bottle? Availability and presentation of oral artemisinin compounds at retail pharmacies in urban Dar-es-Salaam. Malar J 5: 25.
22. Newton PN, Green MD, Fernandez FM, Day NP, White NJ, 2006. Counterfeit anti-infective drugs. Lancet Infect Dis 6: 602-613.
23. Fernandez FM, Cody RB, Green MD, Hampton CY, McGready R, Sengaloundeth S, White NJ, Newton PN, 2006. Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry. ChemMedChem 1: 702-705.
24. Hall KA, Newton PN, Green MD, De Veij M, Vandenabeele P, Pizzanelli D, Mayxay M, Dondorp A, Fernandez FM, 2006. Characterization of counterfeit artesunate antimalarial tablets from southeast Asia. Am J Trop Med Hyg 75: 804-811.
25. Ward SA, Sevene EJ, Hastings IM, Nosten F, McGready R, 2007. Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance. Lancet Infect Dis 7: 136-144.
26. Lee MS, Kerns EH, 1999. LC/MS applications in drug development. Mass Spectrom Rev 18: 187-279.
27. Tomer KB, 2001. Separations combined with mass spectrometry. Chem Rev 101: 297-328.
28. Cody R, Laramee J, Durst H, 2005. Versatile new ion source for the analysis of materials in open air under ambient conditions. Anal Chem 77: 2297-2302.
29. Gaskell S, 1997. Electrospray: principles and practice. J Mass Spectrom 32: 677-688.
30. WHO Model List of Essential Medicines, 2008. Geneva: World Health Organization.
31. World Health Organization, 2006. WHO Guidelines for the Treatment of Malaria. Geneva: World Health Organization.
32. Beers MH, Porter RS, Jones TV, Kaplan JL, Berwits M, 2006. The Merck Manual of Diagnosis and Therapy. Whitehouse Station, NJ: Merck Research Laboratories.
33. Anonymous, 2007. British National Formulary. London: BMJ Publishing Group and RPS Publishing.
34. Ballereau F, Prazuck T, Schrive I, Lafleuriel MT, Rozec D, Fisch A, Lafaix C, 1997. Stability of essential drugs in the field: results of a study conducted over a two-year period in Burkina Faso. Am J Trop Med Hyg 57: 31-36.
35. Roper C, Pearce R, Nair S, Sharp B, Nosten F, Anderson T, 2004. Intercontinental spread of pyrimethamine-resistant malaria. Science 305: 1124.
36. Anon., 2007. Resistance to artemisinin derivatives along the Thai-Cambodian border. Wkly Epidemiol Rec 82: 360.
37. Bousema JT, Gouagna LC, Meutstege AM, Okech BE, Akim NI, Githure JI, Beier JC, Sauerwein RW, 2003. Treatment failure of pyrimethamine-sulphadoxine and induction of Plasmodium falciparum gametocytaemia in children in western Kenya. Trop Med Int Health 8: 427-430.
38. Price R, Nosten F, Simpson JA, Luxemburger C, Phaipun L, ter Kuile F, van Vugt M, Chongsuphajaisiddhi T, White NJ, 1999. Risk factors for gametocyte carriage in uncomplicated falciparum malaria. Am J Trop Med Hyg 60: 1019-1023.
39. Tomson G, Sterky G, 1986. Self-prescribing by way of pharmacies in 3 Asian developing-countries. Lancet 2: 620-622.
40. Wondemagegnehu E, 1999. Counterfeit and Substandard Drugs in Myanmar and Vietnam. Geneva: World Health Organization. WHO Report WHO/EDM/QSM/993.
41. Lon CT, Tsuyuoka R, Phanouvong S, Nivanna N, Socheat D, Sokhan C, Blum N, Christophel EM, Smine A, 2006. Counterfeit and substandard antimalarial drugs in Cambodia. Trans R Soc Trop Med Hyg 100: 1019-1024.
42. Patterson AE, Winch PJ, Gilroy KE, Doumbia S, 2006. Local terminology for medicines to treat fever in Bougouni District, Mali: implications for the introduction and evaluation of malaria treatment policies. Trop Med Int Health 11: 1613-1624.
43. Ratanowijitrasin S, Wondemagegnehu E, 2003. Effective drug regulation: a multicountry study. Essent Drugs Monit 32: 2-4.