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Volumn 120, Issue 1-2, 2011, Pages 130-135

Molecular analysis of pfatp6 and pfmdr1 polymorphisms and their association with in vitro sensitivity in Plasmodium falciparum isolates from the Thai-Myanmar border

Author keywords

Gene amplification; Multidrug resistance; Pfatp6; Pfmdr1; Plasmodium falciparum; Single nucleotide polymorphism

Indexed keywords

ARTESUNATE; CHLOROQUINE; MEFLOQUINE; QUININE;

EID: 80052095101     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2011.07.003     Document Type: Article
Times cited : (32)

References (44)
  • 2
    • 0035873715 scopus 로고    scopus 로고
    • High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance Gene pfmdr1
    • Babiker H.A., Pringle S.J., Abdel-Muhsin A., Mackinnon M., Hunt P., Walliker D. High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance Gene pfmdr1. J. Infect. Dis. 2001, 183:1535-1538.
    • (2001) J. Infect. Dis. , vol.183 , pp. 1535-1538
    • Babiker, H.A.1    Pringle, S.J.2    Abdel-Muhsin, A.3    Mackinnon, M.4    Hunt, P.5    Walliker, D.6
  • 3
    • 0030951090 scopus 로고    scopus 로고
    • Pfmdr1 gene mutation and clinical response to chloroquine in Yaounde, Cameroon
    • Basco L.K., Ringwald P. pfmdr1 gene mutation and clinical response to chloroquine in Yaounde, Cameroon. Trans. R. Soc. Trop. Med. Hyg. 1997, 91:210-211.
    • (1997) Trans. R. Soc. Trop. Med. Hyg. , vol.91 , pp. 210-211
    • Basco, L.K.1    Ringwald, P.2
  • 6
    • 24944572285 scopus 로고    scopus 로고
    • In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003
    • Chaijaroenkul W., Na-Bangchang K.N., Mungthin M., Ward S.A. In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003. Malar. J. 2005, 4:37-43.
    • (2005) Malar. J. , vol.4 , pp. 37-43
    • Chaijaroenkul, W.1    Na-Bangchang, K.N.2    Mungthin, M.3    Ward, S.A.4
  • 7
    • 74249093886 scopus 로고    scopus 로고
    • Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate
    • Chaijaroenkul W., Wisedpanichkij R., Na-Bangchang K. Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate. Acta Trop. 2010, 113:190-194.
    • (2010) Acta Trop. , vol.113 , pp. 190-194
    • Chaijaroenkul, W.1    Wisedpanichkij, R.2    Na-Bangchang, K.3
  • 8
    • 0036467783 scopus 로고    scopus 로고
    • Levels of chloroquine resistance in Plasmodium falciparum are determined by loci other than pfcrt and pfmdr1
    • Chen N., Russell B., Fowler E., Peters J., Cheng Q. Levels of chloroquine resistance in Plasmodium falciparum are determined by loci other than pfcrt and pfmdr1. J. Infect. Dis. 2002, 185:405-407.
    • (2002) J. Infect. Dis. , vol.185 , pp. 405-407
    • Chen, N.1    Russell, B.2    Fowler, E.3    Peters, J.4    Cheng, Q.5
  • 9
    • 19344377032 scopus 로고    scopus 로고
    • Contribution of the pfmdr1 gene to antimalarial drug-resistance
    • Duraisingh M.T., Cowman A.F. Contribution of the pfmdr1 gene to antimalarial drug-resistance. Acta Trop. 2005, 94:181-190.
    • (2005) Acta Trop. , vol.94 , pp. 181-190
    • Duraisingh, M.T.1    Cowman, A.F.2
  • 10
    • 0034732666 scopus 로고    scopus 로고
    • The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin
    • Duraisingh M.T., Jones P., Sambou I., von Seidlein L., Pinder M., Warhurst D.C. The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin. Mol. Biochem. Parasitol. 2000, 108:13-23.
    • (2000) Mol. Biochem. Parasitol. , vol.108 , pp. 13-23
    • Duraisingh, M.T.1    Jones, P.2    Sambou, I.3    von Seidlein, L.4    Pinder, M.5    Warhurst, D.C.6
  • 11
    • 0035946415 scopus 로고    scopus 로고
    • Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum
    • Durand R., Jafari S., Vauzelle J., Delabre J.F., Jesic Z., Le, Bras.J. Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum. Mol. Biochem. Parasitol. 2001, 114:95-102.
    • (2001) Mol. Biochem. Parasitol. , vol.114 , pp. 95-102
    • Durand, R.1    Jafari, S.2    Vauzelle, J.3    Delabre, J.F.4    Jesic, Z.5    Le Bras, J.6
  • 12
    • 39849084773 scopus 로고    scopus 로고
    • Plasmodium falciparum from Para state (Brazil) shows satisfactory in vitro response to artemisinin derivatives and absence of the S769N mutation in the SERCA-type PfATPase6
    • Ferreira I.D., Martinelli A., Rodrigues L.A., do Carmo E.L., do Rosario V.E., Povoa M.M., Cravo P. Plasmodium falciparum from Para state (Brazil) shows satisfactory in vitro response to artemisinin derivatives and absence of the S769N mutation in the SERCA-type PfATPase6. Trop. Med. Int. Health 2008, 13:199-207.
    • (2008) Trop. Med. Int. Health , vol.13 , pp. 199-207
    • Ferreira, I.D.1    Martinelli, A.2    Rodrigues, L.A.3    do Carmo, E.L.4    do Rosario, V.E.5    Povoa, M.M.6    Cravo, P.7
  • 13
    • 33646360203 scopus 로고    scopus 로고
    • Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum
    • Ferreira I.D., Rosario V.E., Cravo P.V. Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum. Malar. J. 2006, 5:1-7.
    • (2006) Malar. J. , vol.5 , pp. 1-7
    • Ferreira, I.D.1    Rosario, V.E.2    Cravo, P.V.3
  • 14
    • 0025269612 scopus 로고
    • Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
    • Foote S.J., Kyle D.E., Martin R.K., Oduola A.M., Forsyth K., Kemp D.J., Cowman A.F. Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 1990, 345:255-258.
    • (1990) Nature , vol.345 , pp. 255-258
    • Foote, S.J.1    Kyle, D.E.2    Martin, R.K.3    Oduola, A.M.4    Forsyth, K.5    Kemp, D.J.6    Cowman, A.F.7
  • 15
    • 0028609975 scopus 로고
    • Chloroquine resistance of Plasmodium falciparum: further evidence for a lack of association with mutations of the pfmdr1 gene
    • Haruki K., Bray P.G., Ward S.A., Hommel M., Ritchie G.Y. Chloroquine resistance of Plasmodium falciparum: further evidence for a lack of association with mutations of the pfmdr1 gene. Trans. R. Soc. Trop. Med. Hyg. 1994, 88:694-698.
    • (1994) Trans. R. Soc. Trop. Med. Hyg. , vol.88 , pp. 694-698
    • Haruki, K.1    Bray, P.G.2    Ward, S.A.3    Hommel, M.4    Ritchie, G.Y.5
  • 16
    • 0036188538 scopus 로고    scopus 로고
    • Mechanisms of resistance of Plasmodium falciparum to antimalarial drugs
    • Hyde J.E. Mechanisms of resistance of Plasmodium falciparum to antimalarial drugs. Microbes Infect. 2002, 4:165-174.
    • (2002) Microbes Infect. , vol.4 , pp. 165-174
    • Hyde, J.E.1
  • 18
    • 0037396367 scopus 로고    scopus 로고
    • The mechanisms of resistance to antimalarial drugs in Plasmodium falciparum
    • Le Bras J., Durand R. The mechanisms of resistance to antimalarial drugs in Plasmodium falciparum. Fundam. Clin. Pharmacol. 2003, 17:147-153.
    • (2003) Fundam. Clin. Pharmacol. , vol.17 , pp. 147-153
    • Le Bras, J.1    Durand, R.2
  • 21
    • 33846600057 scopus 로고    scopus 로고
    • Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania
    • Mugittu K., Genton B., Mshinda H., Beck H.P. Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania. Malar. J. 2006, 5:126-134.
    • (2006) Malar. J. , vol.5 , pp. 126-134
    • Mugittu, K.1    Genton, B.2    Mshinda, H.3    Beck, H.P.4
  • 22
    • 77955471359 scopus 로고    scopus 로고
    • The patterns of mutation and amplification of Plasmodium falciparum pfcrt and pfmdr1 genes in Thailand during the year 1988 to 2003
    • Mungthin M., Suwandittakul N., Chaijaroenkul W., Rungsrihirunrat K., Harnyuttanakorn P., Seugorn A., et al. The patterns of mutation and amplification of Plasmodium falciparum pfcrt and pfmdr1 genes in Thailand during the year 1988 to 2003. Parasitol. Res. 2010, 107:539-545.
    • (2010) Parasitol. Res. , vol.107 , pp. 539-545
    • Mungthin, M.1    Suwandittakul, N.2    Chaijaroenkul, W.3    Rungsrihirunrat, K.4    Harnyuttanakorn, P.5    Seugorn, A.6
  • 23
    • 33847068718 scopus 로고    scopus 로고
    • Current malaria status and distribution of drug resistance in East and Southeast Asia with special focus to Thailand
    • Na-Bangchang K., Congpuong K. Current malaria status and distribution of drug resistance in East and Southeast Asia with special focus to Thailand. Tohoku J. Exp. Med. 2007, 211:99-113.
    • (2007) Tohoku J. Exp. Med. , vol.211 , pp. 99-113
    • Na-Bangchang, K.1    Congpuong, K.2
  • 24
    • 77957557403 scopus 로고    scopus 로고
    • Declining in efficacy of a three-day combination regimen of mefloquine-artesunate in a multi-drug resistance area along the Thai-Myanmar border
    • Na-Bangchang K., Ruengweerayut R., Mahamad P., Ruengweerayut K., Chaijaroenkul W. Declining in efficacy of a three-day combination regimen of mefloquine-artesunate in a multi-drug resistance area along the Thai-Myanmar border. Malar. J. 2010, 9:273-279.
    • (2010) Malar. J. , vol.9 , pp. 273-279
    • Na-Bangchang, K.1    Ruengweerayut, R.2    Mahamad, P.3    Ruengweerayut, K.4    Chaijaroenkul, W.5
  • 25
    • 0035724047 scopus 로고    scopus 로고
    • Mutations in the pfmdr1, dhfr and dhps genes of Plasmodium falciparum are associated with in-vivo drug resistance in West Papua, Indonesia
    • Nagesha H.S., Din S., Casey G.J., Susanti A.I., Fryauff D.J., Reeder J.C., Cowmanm A.F. Mutations in the pfmdr1, dhfr and dhps genes of Plasmodium falciparum are associated with in-vivo drug resistance in West Papua, Indonesia. Trans. R. Soc. Trop. Med. Hyg. 2001, 95:43-49.
    • (2001) Trans. R. Soc. Trop. Med. Hyg. , vol.95 , pp. 43-49
    • Nagesha, H.S.1    Din, S.2    Casey, G.J.3    Susanti, A.I.4    Fryauff, D.J.5    Reeder, J.C.6    Cowmanm, A.F.7
  • 27
    • 68049146050 scopus 로고    scopus 로고
    • Artemisinin-resistant malaria in Asia
    • Noedl H., Socheat D., Satimai W. Artemisinin-resistant malaria in Asia. N. Engl. J. Med. 2009, 361:540-541.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 540-541
    • Noedl, H.1    Socheat, D.2    Satimai, W.3
  • 34
    • 0034708162 scopus 로고    scopus 로고
    • Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
    • Reed M.B., Saliba K.J., Caruana S.R., Kirk K., Cowman A.F. Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature 2000, 403:906-909.
    • (2000) Nature , vol.403 , pp. 906-909
    • Reed, M.B.1    Saliba, K.J.2    Caruana, S.R.3    Kirk, K.4    Cowman, A.F.5
  • 35
    • 23744435838 scopus 로고    scopus 로고
    • Pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum
    • Sidhu A.B., Valderramos S.G., Fidock D.A. pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum. Mol. Microbiol. 2005, 57:913-926.
    • (2005) Mol. Microbiol. , vol.57 , pp. 913-926
    • Sidhu, A.B.1    Valderramos, S.G.2    Fidock, D.A.3
  • 37
    • 0017311840 scopus 로고
    • Human malaria parasites in continuous culture
    • Trager W., Jensen J.B. Human malaria parasites in continuous culture. Science 1976, 193:673-675.
    • (1976) Science , vol.193 , pp. 673-675
    • Trager, W.1    Jensen, J.B.2
  • 38
    • 0036562621 scopus 로고    scopus 로고
    • In vitro chloroquine susceptibility and PCR analysis of pfcrt and pfmdr1 polymorphisms in Plasmodium falciparum isolates from Senegal
    • Thomas S.M., Ndir O., Dieng T., Mboup S., Wypij D., Maguire J.H., Wirth D.F. In vitro chloroquine susceptibility and PCR analysis of pfcrt and pfmdr1 polymorphisms in Plasmodium falciparum isolates from Senegal. Am. J. Trop. Med. Hyg. 2002, 66:474-480.
    • (2002) Am. J. Trop. Med. Hyg. , vol.66 , pp. 474-480
    • Thomas, S.M.1    Ndir, O.2    Dieng, T.3    Mboup, S.4    Wypij, D.5    Maguire, J.H.6    Wirth, D.F.7
  • 40
    • 33644988310 scopus 로고    scopus 로고
    • In vivo sensitivity monitoring of mefloquine monotherapy and artesunate-mefloquine combinations for the treatment of uncomplicated falciparum malaria in Thailand in 2003
    • Vijaykadga S., Rojanawatsirivej C., Cholpol S., Phoungmaneem D., Nakavej A., Wongsrichanalai C. In vivo sensitivity monitoring of mefloquine monotherapy and artesunate-mefloquine combinations for the treatment of uncomplicated falciparum malaria in Thailand in 2003. Trop. Med. Int. Health 2003, 11:211-219.
    • (2003) Trop. Med. Int. Health , vol.11 , pp. 211-219
    • Vijaykadga, S.1    Rojanawatsirivej, C.2    Cholpol, S.3    Phoungmaneem, D.4    Nakavej, A.5    Wongsrichanalai, C.6
  • 42
    • 0027171599 scopus 로고
    • PCR and strain identification in Plasmodium falciparum
    • Wooden J., Kyes S., Sibley C.H. PCR and strain identification in Plasmodium falciparum. Parasitol. Today 1993, 9:303-305.
    • (1993) Parasitol. Today , vol.9 , pp. 303-305
    • Wooden, J.1    Kyes, S.2    Sibley, C.H.3
  • 43
    • 0031836529 scopus 로고    scopus 로고
    • Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance
    • Zalis M.G., Pang L., Silveira M.S., Milhous W.K., Wirth D.F. Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance. Am. J. Trop. Med. Hyg. 1998, 58:630-637.
    • (1998) Am. J. Trop. Med. Hyg. , vol.58 , pp. 630-637
    • Zalis, M.G.1    Pang, L.2    Silveira, M.S.3    Milhous, W.K.4    Wirth, D.F.5
  • 44
    • 47349124330 scopus 로고    scopus 로고
    • No PfATPase6 S769N mutation found in Plasmodium falciparum isolates from China
    • Zhang G.Q., Guan Y.Y., Zheng B., Wu S., Tang L.H. No PfATPase6 S769N mutation found in Plasmodium falciparum isolates from China. Malar. J. 2008, 8:7-12.
    • (2008) Malar. J. , vol.8 , pp. 7-12
    • Zhang, G.Q.1    Guan, Y.Y.2    Zheng, B.3    Wu, S.4    Tang, L.H.5


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