Tandem enzymatic oxygenations in biosynthesis of epoxyquinone pharmacophore of manumycin-type metabolites

Chemistry and Biology

Volumn 20, Issue 7, 2013, Pages 879-887

  Rui, Zhe ^a   Sandy, Moriah ^a   Jung, Brian ^a   Zhang, Wenjun ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 4 HYDROXYL BENZOIC ACID; ADENOSINE TRIPHOSPHATE DEPENDENT ADENYLASE; ASUE 1 PROTEIN; ASUE 3 PROTEIN; BENZOIC ACID DERIVATIVE; CARRIER PROTEINS AND BINDING PROTEINS; DRUG METABOLITE; EPOXYQUINONE; MANUMYCIN; QUERCETIN; QUINONE DERIVATIVE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE CLUSTER; IN VITRO STUDY; IN VIVO STUDY; METABOLITE; NONHUMAN; OXYGENATION; PHARMACOPHORE; PRIORITY JOURNAL;

BENZOIC ACID; BENZOQUINONES; DINITROCRESOLS; MIXED FUNCTION OXYGENASES; MULTIGENE FAMILY; OXIDOREDUCTASES; OXYGEN; POLYENES; POLYUNSATURATED ALKAMIDES; STREPTOMYCES; SUBSTRATE SPECIFICITY;

EID: 84880898014     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.05.006     Document Type: Article

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