Pioglitazone leads to an inactivation and disassembly of complex I of the mitochondrial respiratory chain

BMC Biology

Volumn 11, Issue , 2013, Pages

  García Ruiz, Inmaculada ^a   Solís Muñoz, Pablo ^b   Fernández Moreira, Daniel ^c   Muñoz Yagüe, Teresa ^a   Solís Herruzo, José A ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

^c Department of Bromatology and Food Hygiene Military Center of Veterinary of Defense   (Spain)

Author keywords

ATP; Mitochondrial respiratory chain; Pioglitazone; Proteomic; Thiazolidinediones

Indexed keywords

MUS;

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADENOSINE TRIPHOSPHATE; CHAPERONE; HEAT SHOCK PROTEIN; PIOGLITAZONE; PPARGC1A PROTEIN, HUMAN; PROHIBITIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1; TRITIUM; UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL; ARTICLE; C57BL MOUSE; CELL STRAIN HEPG2; DRUG EFFECT; ELECTRON TRANSPORT; ENZYME ACTIVATION; ENZYMOLOGY; GENETIC TRANSCRIPTION; GENETICS; HUMAN; LIVER MITOCHONDRION; METABOLISM; MITOCHONDRIAL MEMBRANE; MOLECULAR WEIGHT; MOUSE; PROTEIN SUBUNIT; UPREGULATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX III; ENZYME ACTIVATION; HEAT-SHOCK PROTEINS; HEP G2 CELLS; HUMANS; MICE; MICE, INBRED C57BL; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANES; MOLECULAR CHAPERONES; MOLECULAR WEIGHT; NADH DEHYDROGENASE; PROTEIN SUBUNITS; REPRESSOR PROTEINS; SP1 TRANSCRIPTION FACTOR; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRITIUM; UP-REGULATION;

EID: 84880886271     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-11-88     Document Type: Article

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