An iterative, bimodular nonribosomal peptide synthetase that converts anthranilate and tryptophan into tetracyclic asperlicins

Chemistry and Biology

Volumn 20, Issue 7, 2013, Pages 870-878

  Gao, Xue ^a   Jiang, Wei ^c   Jiménez Osés, Gonzalo ^b   Choi, Moon Seok ^a   Houk, Kendall N ^b   Tang, Yi ^a,b   Walsh, Christopher T ^c  

^a Department of Civil and Environmental Engineering   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRANILIC ACID; ASPA PROTEIN; ASPERLICIN; ASPERLICIN C; ASPERLICIN D; NONRIBOSOMAL PEPTIDE SYNTHETASE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATION; CONTROLLED STUDY; CYCLIZATION; ENZYME ACTIVITY; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; TERMINAL CONDENSATION DOMAIN;

ASPERGILLUS; BENZODIAZEPINONES; BIOCATALYSIS; CYCLIZATION; HOLOENZYMES; MODELS, MOLECULAR; OLIGOPEPTIDES; ORTHO-AMINOBENZOATES; PEPTIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; SOLUBILITY; STEREOISOMERISM; TRYPTOPHAN;

EID: 84880873148     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.04.019     Document Type: Article

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