메뉴 건너뛰기




Volumn 14, Issue 1, 2013, Pages

A new approach for prediction of tumor sensitivity to targeted drugs based on functional data

Author keywords

[No Author keywords available]

Indexed keywords

DRUG-PROTEIN INTERACTIONS; FUNCTIONAL PERTURBATION; GENETIC CHARACTERIZATION; LEAVE-ONE-OUT CROSS VALIDATIONS; PREDICTION ACCURACY; SENSITIVITY PREDICTION; SMALL-MOLECULE DRUGS; THERAPEUTIC STRATEGY;

EID: 84880861643     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-14-239     Document Type: Article
Times cited : (35)

References (38)
  • 1
    • 58149398623 scopus 로고    scopus 로고
    • Translation of the Philadelphia chromosome into therapy for CML
    • Druker BJ. Translation of the Philadelphia chromosome into therapy for CML. Blood 2008, 112(13):4808-17.
    • (2008) Blood , vol.112 , Issue.13 , pp. 4808-4817
    • Druker, B.J.1
  • 2
    • 9244222261 scopus 로고    scopus 로고
    • Targeted cancer therapy
    • Sawyers C. Targeted cancer therapy. Nature 2004, 432:294-297.
    • (2004) Nature , vol.432 , pp. 294-297
    • Sawyers, C.1
  • 3
    • 2442517439 scopus 로고    scopus 로고
    • Targeting targeted therapy
    • Green MR. Targeting targeted therapy. New England J Med 2004, 350:2191-2193.
    • (2004) New England J Med , vol.350 , pp. 2191-2193
    • Green, M.R.1
  • 4
    • 3543037572 scopus 로고    scopus 로고
    • Molecularly targeted therapy: have the floodgates opened?
    • Druker BJ. Molecularly targeted therapy: have the floodgates opened?. Oncologist 2004, 9:357-360.
    • (2004) Oncologist , vol.9 , pp. 357-360
    • Druker, B.J.1
  • 6
    • 24944497371 scopus 로고    scopus 로고
    • Features of selective kinase inhibitors
    • Knight ZA, Shokat KM. Features of selective kinase inhibitors. Chem Biol 2005, 12(6):621-637.
    • (2005) Chem Biol , vol.12 , Issue.6 , pp. 621-637
    • Knight, Z.A.1    Shokat, K.M.2
  • 7
    • 67651006061 scopus 로고    scopus 로고
    • Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
    • Sos ML, et al. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest 2009, 119(6):1727-1740.
    • (2009) J Clin Invest , vol.119 , Issue.6 , pp. 1727-1740
    • Sos, M.L.1
  • 9
    • 0035845531 scopus 로고    scopus 로고
    • Chemosensitivity prediction by transcriptional profiling
    • Staunton JE, et al. Chemosensitivity prediction by transcriptional profiling. Proc Natl Acad Sci 2001, 98:10787-10792.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 10787-10792
    • Staunton, J.E.1
  • 13
    • 74549168922 scopus 로고    scopus 로고
    • Identifying drug effects via pathway alterations using an integer linear programming optimization formulation on phosphoproteomic data
    • Mitsos A, Melas IN, Siminelakis P, Chairakaki AD, Saez-Rodriguez J, Alexopoulos LG. Identifying drug effects via pathway alterations using an integer linear programming optimization formulation on phosphoproteomic data. PLoS Comput Biol 2009, 5(12):e1000591+. http://dx.doi.org/10.1371/journal.pcbi.1000591.
    • (2009) PLoS Comput Biol , vol.5 , Issue.12
    • Mitsos, A.1    Melas, I.N.2    Siminelakis, P.3    Chairakaki, A.D.4    Saez-Rodriguez, J.5    Alexopoulos, L.G.6
  • 14
    • 79954517618 scopus 로고    scopus 로고
    • Molecular tumor profiling for prediction of response to anticancer therapies
    • Walther Z, Sklar J. Molecular tumor profiling for prediction of response to anticancer therapies. Cancer J 2011, 17(2):71-9.
    • (2011) Cancer J , vol.17 , Issue.2 , pp. 71-79
    • Walther, Z.1    Sklar, J.2
  • 15
    • 84859169877 scopus 로고    scopus 로고
    • The cancer cell line encyclopedia enables Predictive modelling of anticancer drug sensitivity
    • Barretina J, et al. The cancer cell line encyclopedia enables Predictive modelling of anticancer drug sensitivity. Nature 2012, 483(7391):603-607. [http://dx.doi.org/10.1038/nature11003].
    • (2012) Nature , vol.483 , Issue.7391 , pp. 603-607
    • Barretina, J.1
  • 17
    • 84877823775 scopus 로고    scopus 로고
    • Anticancer drug sensitivity analysis: an integrated approach applied to Erlotinib sensitivity prediction in the CCLE database
    • Washington DC
    • Pal R, Berlow N, Haider S. Anticancer drug sensitivity analysis: an integrated approach applied to Erlotinib sensitivity prediction in the CCLE database. IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) 2012, 9-12. Washington DC.
    • (2012) IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) , pp. 9-12
    • Pal, R.1    Berlow, N.2    Haider, S.3
  • 19
    • 64249106832 scopus 로고    scopus 로고
    • Mouse xenograft models vs GEM models for human cancer therapeutics
    • Richmond A, Su Y. Mouse xenograft models vs GEM models for human cancer therapeutics. Dis Model Mech 2008, 1(2-3):78-82.
    • (2008) Dis Model Mech , vol.1 , Issue.2-3 , pp. 78-82
    • Richmond, A.1    Su, Y.2
  • 21
    • 0027464950 scopus 로고
    • P53 abnormalities in different subtypes of human sarcomas
    • Andreassen A, Oyjord T, Hovig E, Holm R, Florenes V, et al. p53 abnormalities in different subtypes of human sarcomas. Cancer Res 1993, 53(3):468-471.
    • (1993) Cancer Res , vol.53 , Issue.3 , pp. 468-471
    • Andreassen, A.1    Oyjord, T.2    Hovig, E.3    Holm, R.4    Florenes, V.5
  • 22
    • 33846882630 scopus 로고    scopus 로고
    • Molecular pathogenesis of osteosarcoma
    • Kansara M, Thomas DM. Molecular pathogenesis of osteosarcoma. DNA Cell Biol 2007, 26:1-18.
    • (2007) DNA Cell Biol , vol.26 , pp. 1-18
    • Kansara, M.1    Thomas, D.M.2
  • 25
    • 0034045930 scopus 로고    scopus 로고
    • Involvement of p21Waf1 Cip1 in protein kinase C alpha induced cell cycle progression
    • Besson A, Yong VW. Involvement of p21Waf1 Cip1 in protein kinase C alpha induced cell cycle progression. Mol Cell Biol 2000, 20(13):4580-90.
    • (2000) Mol Cell Biol , vol.20 , Issue.13 , pp. 4580-4590
    • Besson, A.1    Yong, V.W.2
  • 26
    • 77953364958 scopus 로고    scopus 로고
    • Proteasome inhibition with bortezomib suppresses growth and induces apoptosis in osteosarcoma
    • Shapovalov Y, Benavidez D, Zuch D, Eliseev RA. Proteasome inhibition with bortezomib suppresses growth and induces apoptosis in osteosarcoma. Int J Cancer 2010, 127:67-76.
    • (2010) Int J Cancer , vol.127 , pp. 67-76
    • Shapovalov, Y.1    Benavidez, D.2    Zuch, D.3    Eliseev, R.A.4
  • 27
    • 0031780665 scopus 로고    scopus 로고
    • Ubiquitin, E6-AP, and their role in p53 inactivation
    • Scheffner M. Ubiquitin, E6-AP, and their role in p53 inactivation. Pharmacol Ther 1998, 78(3):129-139.
    • (1998) Pharmacol Ther , vol.78 , Issue.3 , pp. 129-139
    • Scheffner, M.1
  • 28
    • 0033035897 scopus 로고    scopus 로고
    • ERK pathway mediates the activation of Cdk2 in IGF1 induced proliferation of human osteosarcoma MG63 cells
    • Zhang W, Lee JC, Kumar S, Gowen M. ERK pathway mediates the activation of Cdk2 in IGF1 induced proliferation of human osteosarcoma MG63 cells. J Bone Miner Res 1999, 14(4):528-535.
    • (1999) J Bone Miner Res , vol.14 , Issue.4 , pp. 528-535
    • Zhang, W.1    Lee, J.C.2    Kumar, S.3    Gowen, M.4
  • 29
    • 84861333261 scopus 로고    scopus 로고
    • High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes
    • Choy E, Hornicek F, MacConaill L, Harmon D, Tariq Z, Garraway L, Duan Z. High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes. Cancer 2012, 118(11):2905-2914.
    • (2012) Cancer , vol.118 , Issue.11 , pp. 2905-2914
    • Choy, E.1    Hornicek, F.2    MacConaill, L.3    Harmon, D.4    Tariq, Z.5    Garraway, L.6    Duan, Z.7
  • 30
    • 24044551995 scopus 로고    scopus 로고
    • PI3K/Akt/mTOR pathway as a target for cancer therapy
    • Morgensztern D, McLeod H. PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 2005, 16(8):797-803.
    • (2005) Anticancer Drugs , vol.16 , Issue.8 , pp. 797-803
    • Morgensztern, D.1    McLeod, H.2
  • 31
    • 0036082913 scopus 로고    scopus 로고
    • ET1 stimulates ERK signaling pathway through sequential activation of PKC and Src in rat myometrial cells
    • Robin P, Boulven I, Desmyter C, Harbon S, Leiber D. ET1 stimulates ERK signaling pathway through sequential activation of PKC and Src in rat myometrial cells. Am J Physiol - Cell Physiol 2002, 283:C251-C260.
    • (2002) Am J Physiol - Cell Physiol , vol.283
    • Robin, P.1    Boulven, I.2    Desmyter, C.3    Harbon, S.4    Leiber, D.5
  • 32
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto Encycolpedia of Genes and Genomes
    • Kanehisa M, Goto S. KEGG: Kyoto Encycolpedia of Genes and Genomes. Nucleic Acids Res 2000, 28:27-30.
    • (2000) Nucleic Acids Res , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 33
    • 84881549066 scopus 로고    scopus 로고
    • [Library containing dissociation constants of Drugs]., Pubchem
    • Pubchem [Library containing dissociation constants of Drugs]. http://pubchem.ncbi.nlm.nih.gov/, Pubchem.
  • 34
    • 84891424303 scopus 로고    scopus 로고
    • A Kinase inhibition map approach for tumor sensitivity prediction and combination therapy design for targeted drugs
    • Pal R, Berlow N. A Kinase inhibition map approach for tumor sensitivity prediction and combination therapy design for targeted drugs. Pacific Symposium on Biocomputing 2012, 351-62. http://psb.stanford.edu/psb-online/proceedings/psb12/pal.pdf.
    • (2012) Pacific Symposium on Biocomputing , pp. 351-362
    • Pal, R.1    Berlow, N.2
  • 35
  • 37
    • 40749162731 scopus 로고    scopus 로고
    • Robust intervention in probabilistic boolean networks
    • Pal R, Datta A, Dougherty ER. Robust intervention in probabilistic boolean networks. IEEE Trans Signal Process 2008, 56:1280-1294.
    • (2008) IEEE Trans Signal Process , vol.56 , pp. 1280-1294
    • Pal, R.1    Datta, A.2    Dougherty, E.R.3
  • 38
    • 69349084710 scopus 로고    scopus 로고
    • Bayesian robustness in the control of gene regulatory networks
    • Pal R, Datta A, Dougherty ER. Bayesian robustness in the control of gene regulatory networks. IEEE Trans Signal Process 2009, 57:3667-3678.
    • (2009) IEEE Trans Signal Process , vol.57 , pp. 3667-3678
    • Pal, R.1    Datta, A.2    Dougherty, E.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.