메뉴 건너뛰기




Volumn 14, Issue 4, 1999, Pages 528-535

ERK pathway mediates the activation of Cdk2 in IGF-1-induced proliferation of human osteosarcoma MG-63 cells

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MITOGEN ACTIVATED PROTEIN KINASE; OLOMOUCINE; SOMATOMEDIN C;

EID: 0033035897     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1999.14.4.528     Document Type: Article
Times cited : (54)

References (42)
  • 1
    • 0028314962 scopus 로고
    • Insulin-like growth factor-1 induces cyclin-D 1 expression in MG 63 human osteosarcoma cell in vitro
    • Furlanetto RW, Harwell SE, Frick KK 1994 Insulin-like growth factor-1 induces cyclin-D 1 expression in MG 63 human osteosarcoma cell in vitro. Mol Endocrinol 8:510-551.
    • (1994) Mol Endocrinol , vol.8 , pp. 510-551
    • Furlanetto, R.W.1    Harwell, S.E.2    Frick, K.K.3
  • 2
    • 0028335994 scopus 로고
    • Insulin-like growth factor-1 activation of extracellular signal-regulated kinase 1 and 2 in growth hormone-secreting cells
    • Webster J, Prager D, Melmed S 1994 Insulin-like growth factor-1 activation of extracellular signal-regulated kinase 1 and 2 in growth hormone-secreting cells. Mol Endocrinol 8:539-544.
    • (1994) Mol Endocrinol , vol.8 , pp. 539-544
    • Webster, J.1    Prager, D.2    Melmed, S.3
  • 3
    • 0027177288 scopus 로고
    • Insulin receptor substrate 1 mediated insulin and insulin-like growth factor1-stimulated maturation of Xenopus oocytes
    • Chuang LM, Myers M, Seidner GA, Birnbaum MJ, White MF, Kahn CR 1990 Insulin receptor substrate 1 mediated insulin and insulin-like growth factor1-stimulated maturation of Xenopus oocytes. Proc Natl Acad Sci USA 90:5173-5175.
    • (1990) Proc Natl Acad Sci USA , vol.90 , pp. 5173-5175
    • Chuang, L.M.1    Myers, M.2    Seidner, G.A.3    Birnbaum, M.J.4    White, M.F.5    Kahn, C.R.6
  • 4
    • 0026498949 scopus 로고
    • Nicotinic agonists, phorbol esters, and growth factors activate two extracellular signal-regulated kinases, ERK1 and ERK2, in bovine chromaffin cells
    • Pavlovic-Surjancev B, Cahill AL, Perlman RL 1992 Nicotinic agonists, phorbol esters, and growth factors activate two extracellular signal-regulated kinases, ERK1 and ERK2, in bovine chromaffin cells. J Neurochem 59:2134-2140.
    • (1992) J Neurochem , vol.59 , pp. 2134-2140
    • Pavlovic-Surjancev, B.1    Cahill, A.L.2    Perlman, R.L.3
  • 5
    • 0027165150 scopus 로고
    • The mitogenic-activated protein kinase signal transduction pathway
    • Davis DJ 1993 The mitogenic-activated protein kinase signal transduction pathway. J Biol Chem 268:14553-14556.
    • (1993) J Biol Chem , vol.268 , pp. 14553-14556
    • Davis, D.J.1
  • 6
    • 0028074621 scopus 로고
    • Ras-dependent growth factor regulation of MEK kinase in PC 12 cells
    • Lange-Carter CA, Johnson GL 1994 Ras-dependent growth factor regulation of MEK kinase in PC 12 cells. Science 265:1458-1461.
    • (1994) Science , vol.265 , pp. 1458-1461
    • Lange-Carter, C.A.1    Johnson, G.L.2
  • 7
    • 0026596576 scopus 로고
    • Serum-, TPA-, and Ras-induced expression from AP-1/Ets-driven promoters requires Raf-1 kinase
    • Bruder JT, Heidecher G, Rapp UR 1992 Serum-, TPA-, and Ras-induced expression from AP-1/Ets-driven promoters requires Raf-1 kinase. Genes Dev 6:545-556.
    • (1992) Genes Dev , vol.6 , pp. 545-556
    • Bruder, J.T.1    Heidecher, G.2    Rapp, U.R.3
  • 9
    • 0026539931 scopus 로고
    • The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product
    • Crews CM, Alessandrini A, Erikson RL 1992 The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science 258:478-480.
    • (1992) Science , vol.258 , pp. 478-480
    • Crews, C.M.1    Alessandrini, A.2    Erikson, R.L.3
  • 10
    • 0023766145 scopus 로고
    • Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
    • Sturgill TW, Ray LB, Erikson E, Mailer JL 1988 Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature 334:715-718.
    • (1988) Nature , vol.334 , pp. 715-718
    • Sturgill, T.W.1    Ray, L.B.2    Erikson, E.3    Mailer, J.L.4
  • 11
    • 0028823892 scopus 로고
    • Mitogen and stress response pathway: MAP kinase cascades and phosphatase regulation in mammalian and yeast
    • Waskiewicz AJ, Cooper JA 1995 Mitogen and stress response pathway: MAP kinase cascades and phosphatase regulation in mammalian and yeast. Curr Opin Cell Biol 7:798-805.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 798-805
    • Waskiewicz, A.J.1    Cooper, J.A.2
  • 12
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall CJ 1995 Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 13
    • 0026481962 scopus 로고
    • Interplay between proliferation and differentiation within the myogenic lineage
    • Olson EN 1992 Interplay between proliferation and differentiation within the myogenic lineage. Dev Biol 154:261-272.
    • (1992) Dev Biol , vol.154 , pp. 261-272
    • Olson, E.N.1
  • 15
    • 0028171292 scopus 로고
    • G1 phase progression: Cyclin on cue
    • Sheer CJ 1994 G1 phase progression: Cyclin on cue. Cell 79:551-555.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sheer, C.J.1
  • 16
    • 0028950016 scopus 로고
    • Effects of phosphorylation by CDK on cyclin binding by CDC2 and CDK2
    • Desai D, Wessling HC, Fisher RP, Morgan DO 1995 Effects of phosphorylation by CDK on cyclin binding by CDC2 and CDK2. Mol Cell Biol 15:345-350.
    • (1995) Mol Cell Biol , vol.15 , pp. 345-350
    • Desai, D.1    Wessling, H.C.2    Fisher, R.P.3    Morgan, D.O.4
  • 17
    • 0026532413 scopus 로고
    • Human cyclin-dependent kinase 2 (Cdk2) is activated during the S and G2 phases of the cell cycle and associated with cyclin A
    • Rosenblatt J, Gu T, Morgan D 1992 Human cyclin-dependent kinase 2 (Cdk2) is activated during the S and G2 phases of the cell cycle and associated with cyclin A. Proc Natl Acad Sci USA 89:2824-2878.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2824-2878
    • Rosenblatt, J.1    Gu, T.2    Morgan, D.3
  • 20
    • 0027494125 scopus 로고
    • Reversal of terminal differentiation and control of DNA replication: Cyclin A and Cdk2 specifically localized at subnuclear sites of DNA replication
    • Cardoso MC, Leonhardt H, Nadal-Ginard B 1993 Reversal of terminal differentiation and control of DNA replication: Cyclin A and Cdk2 specifically localized at subnuclear sites of DNA replication. Cell 74:979-992.
    • (1993) Cell , vol.74 , pp. 979-992
    • Cardoso, M.C.1    Leonhardt, H.2    Nadal-Ginard, B.3
  • 22
    • 0026526437 scopus 로고
    • E2F: A link between the Rb tumor suppresor protein and viral oncoprotein
    • Nevins JR 1992 E2F: A link between the Rb tumor suppresor protein and viral oncoprotein. Science 258:424-429.
    • (1992) Science , vol.258 , pp. 424-429
    • Nevins, J.R.1
  • 23
    • 0024439444 scopus 로고
    • The rentinoblastoma protein is phosphorylated during specific phases of the cell cycle
    • Buchkovich K, Duffy LA, Harlow E 1989 The rentinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 58:1097-1105.
    • (1989) Cell , vol.58 , pp. 1097-1105
    • Buchkovich, K.1    Duffy, L.A.2    Harlow, E.3
  • 24
    • 0028878829 scopus 로고
    • Cell cycle arrest induced by an inhibitor of glucosylcermide synthase: Correlation with cyclin-dependnet kinases
    • Rani CSS, Abe K, Chang Y, Rosenweig N, Saltiel AR, Radin NS, Shayman JA 1995 Cell cycle arrest induced by an inhibitor of glucosylcermide synthase: Correlation with cyclin-dependnet kinases. J Biol Chem 270:2859-2867.
    • (1995) J Biol Chem , vol.270 , pp. 2859-2867
    • Rani, C.S.S.1    Abe, K.2    Chang, Y.3    Rosenweig, N.4    Saltiel, A.R.5    Radin, N.S.6    Shayman, J.A.7
  • 25
    • 0031559807 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2) by FGF-2 and PDGF-BB in normal human osteoblastic and bone marrow stromal cells: Differences in mobility and in-gel renaturation of ERK1 in human, rat, and mouse osteoblastic cells
    • Chaudhary LR, Avioli LV 1997 Activation of extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2) by FGF-2 and PDGF-BB in normal human osteoblastic and bone marrow stromal cells: Differences in mobility and in-gel renaturation of ERK1 in human, rat, and mouse osteoblastic cells. Biochem Biophys Res Commun 238:134-139.
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 134-139
    • Chaudhary, L.R.1    Avioli, L.V.2
  • 26
    • 0029898360 scopus 로고    scopus 로고
    • Mitogenic signaling from the EGF receptor is attenuated by a phospholipase C-γ protein kinase C feed back mechanism
    • Chen P, Xie H, Wells A 1996 Mitogenic signaling from the EGF receptor is attenuated by a phospholipase C-γ protein kinase C feed back mechanism. Mol Biol Cell 76:871-881.
    • (1996) Mol Biol Cell , vol.76 , pp. 871-881
    • Chen, P.1    Xie, H.2    Wells, A.3
  • 27
    • 0028937610 scopus 로고
    • mapk in proliferating cultures of epithelial cells
    • mapk in proliferating cultures of epithelial cells. J Biol Chem 270:7117-7124.
    • (1995) J Biol Chem , vol.270 , pp. 7117-7124
    • Hartsough, M.T.1    Mulder, K.M.2
  • 28
    • 0026320075 scopus 로고
    • Cyclin a is required for onset DNA replication mammalian fibroblasts
    • Girard F, Strausfeld U, Fernandez A, Lamb NJC 1991 Cyclin A is required for onset DNA replication mammalian fibroblasts. Cell 67:1169-1179.
    • (1991) Cell , vol.67 , pp. 1169-1179
    • Girard, F.1    Strausfeld, U.2    Fernandez, A.3    Lamb, N.J.C.4
  • 29
    • 0025885070 scopus 로고
    • Isolation of the human Cdk2 gene that encodes the cyclin A-and adenovirus E1A-associated p33 kinase
    • Tasi LH, Harlow E, Meyerson M 1991 Isolation of the human Cdk2 gene that encodes the cyclin A-and adenovirus E1A-associated p33 kinase. Nature 353:174-177.
    • (1991) Nature , vol.353 , pp. 174-177
    • Tasi, L.H.1    Harlow, E.2    Meyerson, M.3
  • 30
    • 0027318843 scopus 로고
    • Negative regulation of G1 progression in mammalian cells inhibition of cyclin E-dependent kinase by TGF-β
    • Koff A, Ohtsuki M, Polyak K, Roberts JM, Massague J 1993 Negative regulation of G1 progression in mammalian cells inhibition of cyclin E-dependent kinase by TGF-β. Science 260:536-539.
    • (1993) Science , vol.260 , pp. 536-539
    • Koff, A.1    Ohtsuki, M.2    Polyak, K.3    Roberts, J.M.4    Massague, J.5
  • 31
    • 0026713875 scopus 로고
    • Cell cycle regulation of cdk2 activity by phosphorylation of Thr 160 and Tyr 15
    • Gu Y, Rosenblatt J, Morgan DO 1992 Cell cycle regulation of Cdk2 activity by phosphorylation of Thr 160 and Tyr 15. EMBO J 11:3995-4005.
    • (1992) EMBO J , vol.11 , pp. 3995-4005
    • Gu, Y.1    Rosenblatt, J.2    Morgan, D.O.3
  • 32
    • 0027532449 scopus 로고
    • Phosphorylation independent activation of human cyclin dependent kinase 2 by cyclin A in vitro
    • Connell-Crowley L, Solomon MJ, Wei N, Harper JW 1993 Phosphorylation independent activation of human cyclin dependent kinase 2 by cyclin A in vitro. Mol Biol Cell 4:79-92.
    • (1993) Mol Biol Cell , vol.4 , pp. 79-92
    • Connell-Crowley, L.1    Solomon, M.J.2    Wei, N.3    Harper, J.W.4
  • 33
    • 0026802989 scopus 로고
    • Regulation of rentinoblastoma protein functions by ectopic expression of human cyclins
    • Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA 1992 Regulation of rentinoblastoma protein functions by ectopic expression of human cyclins. Cell 70:993-1006.
    • (1992) Cell , vol.70 , pp. 993-1006
    • Hinds, P.W.1    Mittnacht, S.2    Dulic, V.3    Arnold, A.4    Reed, S.I.5    Weinberg, R.A.6
  • 34
    • 84970709901 scopus 로고
    • Effects of rh-IGF-1 and IGF-II and GH on the growth of normal adults human osteoblast-like cells and human osteogenic sarcoma cells
    • Scheven BA, Hamilton NJ, Fakkldij TM, Dursma SA 1989 Effects of rh-IGF-1 and IGF-II and GH on the growth of normal adults human osteoblast-like cells and human osteogenic sarcoma cells. Growth Regul 1:160-167.
    • (1989) Growth Regul , vol.1 , pp. 160-167
    • Scheven, B.A.1    Hamilton, N.J.2    Fakkldij, T.M.3    Dursma, S.A.4
  • 35
    • 0018869013 scopus 로고
    • Effects of IGF-1 on DNA and protein synthesis in cultural rat calvaria
    • Canalis E 1980 Effects of IGF-1 on DNA and protein synthesis in cultural rat calvaria. J Clin Invest 66:709-719.
    • (1980) J Clin Invest , vol.66 , pp. 709-719
    • Canalis, E.1
  • 36
    • 0023832454 scopus 로고
    • IGF-1 has independent effects on bone matrix formation and cell replication
    • Hock JM, Centrella M, Canalis E 1988 IGF-1 has independent effects on bone matrix formation and cell replication. Endocrinology 122:254-260.
    • (1988) Endocrinology , vol.122 , pp. 254-260
    • Hock, J.M.1    Centrella, M.2    Canalis, E.3
  • 37
    • 0024532580 scopus 로고
    • IGF-1 mediates selective anabolic effects of PTH in bone cultures
    • Canalis E, Centralla M, Burch W, McCuthy TL 1989 IGF-1 mediates selective anabolic effects of PTH in bone cultures. J Clin Invest 83:60-65.
    • (1989) J Clin Invest , vol.83 , pp. 60-65
    • Canalis, E.1    Centralla, M.2    Burch, W.3    McCuthy, T.L.4
  • 38
    • 0023182603 scopus 로고
    • Ras p21 as a potential mediator of insulin action in Xenopus oocytes
    • Korn LJ, Seibel CW, McCormick F, Roth RA 1987 Ras p21 as a potential mediator of insulin action in Xenopus oocytes. Science 236:840-843.
    • (1987) Science , vol.236 , pp. 840-843
    • Korn, L.J.1    Seibel, C.W.2    McCormick, F.3    Roth, R.A.4
  • 40
    • 0029794788 scopus 로고    scopus 로고
    • Involvement of Raf-1 kinase and protein kinase δ in insulin-like growth factor-1-induced brown adipocyte mitogenic signaling cascade: Inhibition by cyclic adenosine 3′,5′-monophosphate
    • Valverde AM, Teresa T, Lorenzo M, Benito M 1996 Involvement of Raf-1 kinase and protein kinase δ in insulin-like growth factor-1-induced brown adipocyte mitogenic signaling cascade: Inhibition by cyclic adenosine 3′,5′-monophosphate. Endocrinology 137:3832-3841.
    • (1996) Endocrinology , vol.137 , pp. 3832-3841
    • Valverde, A.M.1    Teresa, T.2    Lorenzo, M.3    Benito, M.4
  • 41
    • 0031028381 scopus 로고    scopus 로고
    • Cell cycle arrest mediated by the MEK/ mitogen-activated protein kinase pathway
    • Pumiglia KM, Decker S 1997 Cell cycle arrest mediated by the MEK/ mitogen-activated protein kinase pathway. Proc Natl Acad Sci USA 94:448-452.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 448-452
    • Pumiglia, K.M.1    Decker, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.