BAFF Controls Neural Cell Survival through BAFF Receptor

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Tada, Satoru ^a,b   Yasui, Teruhito ^b   Nakatsuji, Yuji ^a   Okuno, Tatsusada ^a   Koda, Toru ^a   Mochizuki, Hideki ^a   Sakoda, Saburo ^c   Kikutani, Hitoshi ^b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c TONEYAMA NATIONAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; B CELL ACTIVATING FACTOR RECEPTOR; COPPER ZINC SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CELL SURVIVAL; CONTROLLED STUDY; DISEASE COURSE; DRUG MECHANISM; EMBRYO; GENETIC DISORDER; LYMPHOCYTE DEPLETION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NERVE CELL; NEWBORN; NONHUMAN; PROTEIN DEFECT; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; B-CELL ACTIVATING FACTOR; B-CELL ACTIVATION FACTOR RECEPTOR; B-LYMPHOCYTES; BONE MARROW CELLS; CELL LINE; CELL SURVIVAL; GENE EXPRESSION; HUMANS; MICE; MICE, KNOCKOUT; NEURONS; SUPEROXIDE DISMUTASE;

EID: 84880837796     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070924     Document Type: Article

References (30)

1. Blesch A, (2006) Neurotrophic factors in neurodegeneration. Brain Pathol 16: 295-303.
2. Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, et al. (2007) Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Rev Neurother 7: 473-485.
3. Tuszynski MH, (2007) Nerve growth factor gene therapy in Alzheimer disease. Alzheimer Dis Assoc Disord 21: 179-189.
4. Nagahara AH, Bernot T, Moseanko R, Brignolo L, Blesch A, et al. (2009) Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene delivery. Exp Neurol 215: 153-159.
5. Kirik D, Georgievska B, Bjorklund A, (2004) Localized striatal delivery of GDNF as a treatment for Parkinson disease. Nat Neurosci 7: 105-110.
6. Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F, (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260: 1130-1132.
7. Azzouz M, Ralph GS, Storkebaum E, Walmsley LE, Mitrophanous KA, et al. (2004) VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 429: 413-417.
8. Kaspar BK, Llado J, Sherkat N, Rothstein JD, Gage FH, (2003) Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 301: 839-842.
9. Sun W, Funakoshi H, Nakamura T, (2002) Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS. J Neurosci 22: 6537-6548.
10. Mackay F, Silveira PA, Brink R, (2007) B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling. Curr Opin Immunol 19: 327-336.
11. Bossen C, Schneider P, (2006) BAFF, APRIL and their receptors: structure, function and signaling. Semin Immunol 18: 263-275.
12. Mackay F, Schneider P, (2009) Cracking the BAFF code. Nat Rev Immunol 9: 491-502.
13. Okuno T, Nakatsuji Y, Kumanogoh A, Moriya M, Ichinose H, et al. (2005) Loss of dopaminergic neurons by the induction of inducible nitric oxide synthase and cyclooxygenase-2 via CD 40: relevance to Parkinson's disease. J Neurosci Res 81: 874-882.
14. Kanzawa T, Sawada M, Kato K, Yamamoto K, Mori H, et al. (2000) Differentiated regulation of allo-antigen presentation by different types of murine microglial cell lines. J Neurosci Res 62: 383-388.
15. Ramanujam M, Wang X, Huang W, Liu Z, Schiffer L, et al. (2006) Similarities and differences between selective and nonselective BAFF blockade in murine SLE. J Clin Invest 116: 724-734.
16. Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, et al. (1994) Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 264: 1772-1775.
17. Henkel JS, Beers DR, Zhao W, Appel SH, (2009) Microglia in ALS: the good, the bad, and the resting. J Neuroimmune Pharmacol 4: 389-398.
18. Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, et al. (2007) Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci 10: 615-622.
19. Yamanaka K, Chun SJ, Boillee S, Fujimori-Tonou N, Yamashita H, et al. (2008) Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat Neurosci 11: 251-253.
20. Tada S, Okuno T, Yasui T, Nakatsuji Y, Sugimoto T, et al. (2011) Deleterious effects of lymphocytes at the early stage of neurodegeneration in an animal model of amyotrophic lateral sclerosis. J Neuroinflammation 8: 19.
21. Beers DR, Henkel JS, Zhao W, Wang J, Appel SH, (2008) CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. Proc Natl Acad Sci U S A 105: 15558-15563.
22. Chiu IM, Chen A, Zheng Y, Kosaras B, Tsiftsoglou SA, et al. (2008) T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS. Proc Natl Acad Sci U S A 105: 17913-17918.
23. Naor S, Keren Z, Bronshtein T, Goren E, Machluf M, et al. (2009) Development of ALS-like disease in SOD-1 mice deficient of B lymphocytes. J Neurol 256: 1228-1235.
24. Chen J, Aguilera G, (2010) Vasopressin protects hippocampal neurones in culture against nutrient deprivation or glutamate-induced apoptosis. J Neuroendocrinol 22: 1072-1081.
25. Li M, Ona VO, Guegan C, Chen M, Jackson-Lewis V, et al. (2000) Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 288: 335-339.
26. Kostic V, Jackson-Lewis V, de Bilbao F, Dubois-Dauphin M, Przedborski S, (1997) Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science 277: 559-562.
27. Nawa M, Kage-Nakadai E, Aiso S, Okamoto K, Mitani S, et al. (2012) Reduced expression of BTBD10, an Akt activator, leads to motor neuron death. Cell Death Differ 19: 1398-1407.
28. Dewil M, Lambrechts D, Sciot R, Shaw PJ, Ince PG, et al. (2007) Vascular endothelial growth factor counteracts the loss of phospho-Akt preceding motor neurone degeneration in amyotrophic lateral sclerosis. Neuropathol Appl Neurobiol 33: 499-509.
29. Tolosa L, Mir M, Olmos G, Llado J, (2009) Vascular endothelial growth factor protects motoneurons from serum deprivation-induced cell death through phosphatidylinositol 3-kinase-mediated p38 mitogen-activated protein kinase inhibition. Neuroscience 158: 1348-1355.
30. Kieran D, Sebastia J, Greenway MJ, King MA, Connaughton D, et al. (2008) Control of motoneuron survival by angiogenin. J Neurosci 28: 14056-14061.