Vascular endothelial growth factor counteracts the loss of phospho-Akt preceding motor neurone degeneration in amyotrophic lateral sclerosis

Neuropathology and Applied Neurobiology

Volumn 33, Issue 5, 2007, Pages 499-509

  Dewil, M ^a,b   Lambrechts, D ^c   Sciot, R ^a   Shaw, P J ^d   Ince, P G ^d   Robberecht, W ^a,b   Van Den Bosch, L ^a,e  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

^e Laboratory for Neurobiology   (Belgium)

Author keywords

Amyotrophic lateral sclerosis; Apoptosis; Motoneurone; Neurodegeneration; Protein kinase B; Vascular endothelial growth factor

Indexed keywords

PROTEIN KINASE B; VASCULOTROPIN;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG INHIBITION; DRUG MECHANISM; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOTOR NERVE; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BLOTTING, WESTERN; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, TRANSGENIC; MIDDLE AGED; MOTOR NEURONS; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SPINAL CORD; SUPEROXIDE DISMUTASE; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 34548552816     PISSN: 03051846     EISSN: 13652990     Source Type: Journal    
DOI: 10.1111/j.1365-2990.2007.00850.x     Document Type: Article

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