-
1
-
-
80052398365
-
Alpha-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
-
21841800 10.1038/nature10324 1:CAS:528:DC%2BC3MXhtFWku7nM
-
Bartels T, Choi JG, Selkoe DJ (2011) alpha-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation. Nature 477:107-111
-
(2011)
Nature
, vol.477
, pp. 107-111
-
-
Bartels, T.1
Choi, J.G.2
Selkoe, D.J.3
-
2
-
-
0031684499
-
Discovering transthyretin amyloid fibril inhibitors by limited screening
-
9784876 10.1016/S0968-0896(98)00130-8 1:CAS:528:DyaK1cXmtFOrurc%3D
-
Baures PW, Peterson SA, Kelly JW (1998) Discovering transthyretin amyloid fibril inhibitors by limited screening. Bioorg Med Chem 6:1389-1401
-
(1998)
Bioorg Med Chem
, vol.6
, pp. 1389-1401
-
-
Baures, P.W.1
Peterson, S.A.2
Kelly, J.W.3
-
3
-
-
58149364663
-
Use of a free radical method to evaluate antioxidant activity
-
10.1016/S0023-6438(95)80008-5 1:CAS:528:DyaK2MXjvV2itLw%3D
-
Brand-Williams W, Cuvelier ME, Berset C (1995) Use of a free radical method to evaluate antioxidant activity. LWT-Food Sci Technol. 28:25-30
-
(1995)
LWT-Food Sci Technol.
, vol.28
, pp. 25-30
-
-
Brand-Williams, W.1
Cuvelier, M.E.2
Berset, C.3
-
4
-
-
0034601964
-
Chiral nonracemic C2-symmetry biphenyls by desymmetrization of 6,6′,2,2′-tetramethoxy-1,1′-biphenyl
-
10.1016/S0957-4166(00)00410-9 1:CAS:528:DC%2BD3cXoslaltrk%3D
-
Delogu G, Fabbri D, Dettori MA, Forni A, Casalone G (2000) Chiral nonracemic C2-symmetry biphenyls by desymmetrization of 6,6′,2,2′- tetramethoxy-1,1′-biphenyl. Tetrahedron Asymmetry 11:4417-4427
-
(2000)
Tetrahedron Asymmetry
, vol.11
, pp. 4417-4427
-
-
Delogu, G.1
Fabbri, D.2
Dettori, M.A.3
Forni, A.4
Casalone, G.5
-
5
-
-
44949244899
-
Development of novel antiatherogenic biaryls: Design, synthesis, and reactivity
-
18465848 10.1021/jm7014793 1:CAS:528:DC%2BD1cXlslSmsLc%3D
-
Delomenede M, Bedos-Belval F, Duran H, Vindis C, Baltas M, Negre-Salvayre A (2008) Development of novel antiatherogenic biaryls: design, synthesis, and reactivity. J Med Chem 51:3171-3181
-
(2008)
J Med Chem
, vol.51
, pp. 3171-3181
-
-
Delomenede, M.1
Bedos-Belval, F.2
Duran, H.3
Vindis, C.4
Baltas, M.5
Negre-Salvayre, A.6
-
6
-
-
0023694189
-
Synthesis and anti-inflammatory activity of substituted (e)-4-phenyl-3-buten-2-ones
-
10.1016/0223-5234(88)90212-7 1:CAS:528:DyaL1MXhslarsrw%3D
-
Elias G, Rao MNA (1988) Synthesis and anti-inflammatory activity of substituted (e)-4-phenyl-3-buten-2-ones. Eur J Med Chem 23:379-380
-
(1988)
Eur J Med Chem
, vol.23
, pp. 379-380
-
-
Elias, G.1
Rao, M.N.A.2
-
7
-
-
84872687901
-
Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism
-
23064436 10.1016/j.nbd.2012.10.011 1:CAS:528:DC%2BC3sXhs1egt7g%3D
-
Hauser DN, Hastings TG (2013) Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism. Neurobiol Dis 51:35-42
-
(2013)
Neurobiol Dis
, vol.51
, pp. 35-42
-
-
Hauser, D.N.1
Hastings, T.G.2
-
8
-
-
52049098478
-
Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein
-
18775438 10.1016/j.jmb.2008.08.039 1:CAS:528:DC%2BD1cXhtFeksbfP
-
Hong DP, Fink AL, Uversky VN (2008) Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein. J Mol Biol 383:214-223
-
(2008)
J Mol Biol
, vol.383
, pp. 214-223
-
-
Hong, D.P.1
Fink, A.L.2
Uversky, V.N.3
-
9
-
-
59149100921
-
Optical properties of amyloid stained by Congo red: History and mechanisms
-
19019688 10.1016/j.micron.2008.10.002 1:CAS:528:DC%2BD1MXhvVSgtL8%3D
-
Howie AJ, Brewer DB (2009) Optical properties of amyloid stained by Congo red: history and mechanisms. Micron 40:285-301
-
(2009)
Micron
, vol.40
, pp. 285-301
-
-
Howie, A.J.1
Brewer, D.B.2
-
10
-
-
20444412385
-
A new method for purification of recombinant human alpha-synuclein in Escherichia coli
-
15939304 10.1016/j.pep.2005.02.014 1:CAS:528:DC%2BD2MXltFejurc%3D
-
Huang CJ, Ren GP, Zhou H, Wang CC (2005) A new method for purification of recombinant human alpha-synuclein in Escherichia coli. Protein Expr Purif 42:173-177
-
(2005)
Protein Expr Purif
, vol.42
, pp. 173-177
-
-
Huang, C.J.1
Ren, G.P.2
Zhou, H.3
Wang, C.C.4
-
11
-
-
1842612537
-
Spectroscopic studies on the interaction of cinnamic acid and its hydroxyl derivatives with human serum albumin
-
10.1016/j.molstruc.2004.01.003
-
Jiang M, Xie MX, Zheng D, Liu Y, Li XY, Chen X (2004) Spectroscopic studies on the interaction of cinnamic acid and its hydroxyl derivatives with human serum albumin. J Mol Struct 692:71-80
-
(2004)
J Mol Struct
, vol.692
, pp. 71-80
-
-
Jiang, M.1
Xie, M.X.2
Zheng, D.3
Liu, Y.4
Li, X.Y.5
Chen, X.6
-
12
-
-
59449097315
-
Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function
-
19033821 10.1097/FJC.0b013e31818aed93 1:CAS:528:DC%2BD1cXhsVajur7F
-
Liu YZ, Dolence J, Ren J, Rao MNA, Sreejayan N (2008) Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function. J Cardiovasc Pharmacol 52:422-429
-
(2008)
J Cardiovasc Pharmacol
, vol.52
, pp. 422-429
-
-
Liu, Y.Z.1
Dolence, J.2
Ren, J.3
Rao, M.N.A.4
Sreejayan, N.5
-
13
-
-
0032567892
-
Oxidative coupling of 4-substituted 2-methoxy phenols using methyltributylammonium permanganate in dichloromethane
-
10.1016/S0040-4039(97)10665-7 1:CAS:528:DyaK1cXhtF2ktb8%3D
-
Marques FA, Simonelli F, Oliveira ARM, Gohr GL, Leal PC (1998) Oxidative coupling of 4-substituted 2-methoxy phenols using methyltributylammonium permanganate in dichloromethane. Tetrahedron Lett 39:943-946
-
(1998)
Tetrahedron Lett
, vol.39
, pp. 943-946
-
-
Marques, F.A.1
Simonelli, F.2
Oliveira, A.R.M.3
Gohr, G.L.4
Leal, P.C.5
-
14
-
-
32244432511
-
-
CRC Press, Taylor & Francis Group, Boca Raton
-
Montalti M, Credi A, Prodi L, Gandolfi MT (2006) Handbook of photochemistry. CRC Press, Taylor & Francis Group, Boca Raton, pp 561-600
-
(2006)
Handbook of Photochemistry
, pp. 561-600
-
-
Montalti, M.1
Credi, A.2
Prodi, L.3
Gandolfi, M.T.4
-
15
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
6606682 10.1016/0022-1759(83)90303-4 1:STN:280:DyaL2c%2FovFSmtw%3D%3D
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
16
-
-
71949086967
-
Molecular pathogenesis of protein misfolding diseases: Pathological molecular environments versus quality control systems against misfolded proteins
-
19643812 10.1093/jb/mvp119 1:CAS:528:DC%2BD1MXhsFaktb7I
-
Naiki H, Nagai Y (2009) Molecular pathogenesis of protein misfolding diseases: pathological molecular environments versus quality control systems against misfolded proteins. J Biochem 146:751-756
-
(2009)
J Biochem
, vol.146
, pp. 751-756
-
-
Naiki, H.1
Nagai, Y.2
-
17
-
-
34047174521
-
A simple and highly efficient method for the synthesis of chalcones by using borontrifluoride-etherate
-
10.1016/j.tetlet.2007.03.054 1:CAS:528:DC%2BD2sXjvF2rsL0%3D
-
Narender T, Reddy KP (2007) A simple and highly efficient method for the synthesis of chalcones by using borontrifluoride-etherate. Tetrahedron Lett 48:3177-3180
-
(2007)
Tetrahedron Lett
, vol.48
, pp. 3177-3180
-
-
Narender, T.1
Reddy, K.P.2
-
18
-
-
33644945380
-
Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro
-
16524383 10.1111/j.1471-4159.2006.03707.x 1:CAS:528:DC%2BD28Xjslars7c%3D
-
Ono K, Yamada M (2006) Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro. J Neurochem 97:105-115
-
(2006)
J Neurochem
, vol.97
, pp. 105-115
-
-
Ono, K.1
Yamada, M.2
-
19
-
-
77955366745
-
Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: Implications for Parkinson's disease pathogenesis and therapies
-
A. Bjorklund M. Cenci (eds) Elsevier Science BV Amsterdam 10.1016/S0079-6123(10)83007-9
-
Oueslati A, Fournier M, Lashuel HA (2010) Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: implications for Parkinson's disease pathogenesis and therapies. In: Bjorklund A, Cenci M (eds) Recent Advances in Parkinsons Disease: Basic Research. Elsevier Science BV, Amsterdam, pp 115-145
-
(2010)
Recent Advances in Parkinsons Disease: Basic Research
, pp. 115-145
-
-
Oueslati, A.1
Fournier, M.2
Lashuel, H.A.3
-
20
-
-
34548570431
-
Free radical scavenging and radioprotective activity of dehydrozingerone against whole body gamma irradiation in Swiss albino mice
-
17765885 10.1016/j.cbi.2007.07.006 1:CAS:528:DC%2BD2sXhtVCit77M
-
Parihar VK, Dhawan J, Kumar S, Manjula SN, Subramanian G, Unnikrishnan MK, Rao CM (2007) Free radical scavenging and radioprotective activity of dehydrozingerone against whole body gamma irradiation in Swiss albino mice. Chem Biol Interact 170:49-58
-
(2007)
Chem Biol Interact
, vol.170
, pp. 49-58
-
-
Parihar, V.K.1
Dhawan, J.2
Kumar, S.3
Manjula, S.N.4
Subramanian, G.5
Unnikrishnan, M.K.6
Rao, C.M.7
-
21
-
-
77952962215
-
Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells
-
20525240 10.1186/1476-4598-9-137
-
Pisano M, Pagnan G, Dettori MA, Cossu S, Caffa I, Sassu I, Emionite L, Fabbri D, Cilli M, Pastorino F, Palmieri G, Delogu G, Ponzoni M, Rozzo C (2010) Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells. Mol Cancer 9:137-148
-
(2010)
Mol Cancer
, vol.9
, pp. 137-148
-
-
Pisano, M.1
Pagnan, G.2
Dettori, M.A.3
Cossu, S.4
Caffa, I.5
Sassu, I.6
Emionite, L.7
Fabbri, D.8
Cilli, M.9
Pastorino, F.10
Palmieri, G.11
Delogu, G.12
Ponzoni, M.13
Rozzo, C.14
-
22
-
-
0032053805
-
Physico-chemical properties and antioxidant activities of methoxy phenols
-
9607603 10.1016/S0891-5849(97)00382-1 1:STN:280:DyaK1c3mvVKiuw%3D%3D
-
Priyadarsini KI, Guha SN, Rao MNA (1998) Physico-chemical properties and antioxidant activities of methoxy phenols. Free Radic Biol Med 24:933-941
-
(1998)
Free Radic Biol Med
, vol.24
, pp. 933-941
-
-
Priyadarsini, K.I.1
Guha, S.N.2
Rao, M.N.A.3
-
23
-
-
0032982508
-
Antioxidant activity applying an improved ABTS radical cation decolorization assay
-
10381194 10.1016/S0891-5849(98)00315-3 1:CAS:528:DyaK1MXjvVakt7o%3D
-
Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26:1231-1237
-
(1999)
Free Radic Biol Med
, vol.26
, pp. 1231-1237
-
-
Re, R.1
Pellegrini, N.2
Proteggente, A.3
Pannala, A.4
Yang, M.5
Rice-Evans, C.6
-
24
-
-
72949094441
-
Are there common biochemical and molecular mechanisms controlling manganism and parkisonism
-
10.1007/s12017-009-8088-8 1:CAS:528:DC%2BD1MXhsFClur3F
-
Roth J (2009) Are there common biochemical and molecular mechanisms controlling manganism and parkisonism. NeuroMol Med 11:281-296
-
(2009)
NeuroMol Med
, vol.11
, pp. 281-296
-
-
Roth, J.1
-
25
-
-
84876790040
-
Oxidative and nitrative alpha-synuclein modifications and proteostatic stress: Implications for disease mechanisms and interventions in synucleinopathies
-
10.1111/jnc.12226 23452040
-
Schildknecht S, Gerding HR, Karreman C, Drescher M, Lashuel HA, Outeiro TF, Di Monte DA, Leist M (2013) Oxidative and nitrative alpha-synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies. J Neurochem. doi: 10.1111/jnc.12226
-
(2013)
J Neurochem
-
-
Schildknecht, S.1
Gerding, H.R.2
Karreman, C.3
Drescher, M.4
Lashuel, H.A.5
Outeiro, T.F.6
Di Monte, D.A.7
Leist, M.8
-
26
-
-
79951926837
-
Differential protection of pre-, co- and post-treatment of curcumin against hydrogen peroxide in PC12 cells
-
20488840 10.1177/0960327110371696 1:CAS:528:DC%2BC3MXktlahu7k%3D
-
Siddiqui MA, Kashyap MP, Kumar V, Tripathi VK, Khanna VK, Yadav S, Pant AB (2011) Differential protection of pre-, co- and post-treatment of curcumin against hydrogen peroxide in PC12 cells. Hum Exp Toxicol 30:192-198
-
(2011)
Hum Exp Toxicol
, vol.30
, pp. 192-198
-
-
Siddiqui, M.A.1
Kashyap, M.P.2
Kumar, V.3
Tripathi, V.K.4
Khanna, V.K.5
Yadav, S.6
Pant, A.B.7
-
27
-
-
0030839940
-
Stability of curcumin in buffer solutions and characterization of its degradation products
-
9278892 10.1016/S0731-7085(96)02024-9 1:CAS:528:DyaK2sXlvVejtbo%3D
-
Wang YJ, Pan MH, Cheng AL, Lin LI, Ho YS, Hsieh CY, Lin JK (1997) Stability of curcumin in buffer solutions and characterization of its degradation products. J Pharm Biomed Anal 15:1867-1876
-
(1997)
J Pharm Biomed Anal
, vol.15
, pp. 1867-1876
-
-
Wang, Y.J.1
Pan, M.H.2
Cheng, A.L.3
Lin, L.I.4
Ho, Y.S.5
Hsieh, C.Y.6
Lin, J.K.7
-
28
-
-
77951557863
-
Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model
-
20433710 10.1186/1471-2202-11-57
-
Wang MS, Boddapati S, Emadi S, Sierks MR (2010) Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model. BMC Neurosci 11:57
-
(2010)
BMC Neurosci
, vol.11
, pp. 57
-
-
Wang, M.S.1
Boddapati, S.2
Emadi, S.3
Sierks, M.R.4
-
29
-
-
0029985683
-
A rapid and simple screening test for potential inhibitors of tocopherol-mediated peroxidation of LDL lipids
-
8732785 1:CAS:528:DyaK28XivVOms7k%3D
-
Witting PK, Westerlund C, Stocker R (1996) A rapid and simple screening test for potential inhibitors of tocopherol-mediated peroxidation of LDL lipids. J Lipid Res 37:853-867
-
(1996)
J Lipid Res
, vol.37
, pp. 853-867
-
-
Witting, P.K.1
Westerlund, C.2
Stocker, R.3
-
30
-
-
84874372615
-
Oxidative stress-induced posttranslational modifications of alpha-synuclein: Specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity
-
23369945 10.1016/j.mcn.2013.01.004 1:CAS:528:DC%2BC3sXlt1Cjsb0%3D
-
Xiang W, Schlachetzki JC, Helling S, Bussmann JC, Berlinghof M, Schäffer TE, Marcus K, Winkler J, Klucken J, Becker CM (2013) Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity. Mol Cell Neurosci 54:71-83
-
(2013)
Mol Cell Neurosci
, vol.54
, pp. 71-83
-
-
Xiang, W.1
Schlachetzki, J.C.2
Helling, S.3
Bussmann, J.C.4
Berlinghof, M.5
Schäffer, T.E.6
Marcus, K.7
Winkler, J.8
Klucken, J.9
Becker, C.M.10
-
31
-
-
33847265732
-
Rifampicin protects PC12 cells against MPP+-induced apoptosis and inhibits the expression of an alpha-Synuclein multimer
-
17280646 10.1016/j.brainres.2006.12.074 1:CAS:528:DC%2BD2sXisVWhu70%3D
-
Xu J, Wei CZ, Xu CQ, Bennett MC, Zhang GH, Li FC, Tao EX (2007) Rifampicin protects PC12 cells against MPP+-induced apoptosis and inhibits the expression of an alpha-Synuclein multimer. Brain Res 1139:220-225
-
(2007)
Brain Res
, vol.1139
, pp. 220-225
-
-
Xu, J.1
Wei, C.Z.2
Xu, C.Q.3
Bennett, M.C.4
Zhang, G.H.5
Li, F.C.6
Tao, E.X.7
-
32
-
-
79551618617
-
The Targets of Curcumin
-
20955148 10.2174/138945011794815356 1:CAS:528:DC%2BC3MXisFOrsr8%3D
-
Zhou HY, Beevers CS, Huang SL (2011) The Targets of Curcumin. Curr Drug Targets 12:332-347
-
(2011)
Curr Drug Targets
, vol.12
, pp. 332-347
-
-
Zhou, H.Y.1
Beevers, C.S.2
Huang, S.L.3
|