Nitric oxide mediates selective degeneration of hypothalamic orexin neurons through dysfunction of protein disulfide isomerase

Journal of Neuroscience

Volumn 33, Issue 31, 2013, Pages 12557-12568

  Obukuro, Kanae ^a   Nobunaga, Mizuki ^a   Takigawa, Moeko ^a   Morioka, Hiroshi ^a   Hisatsune, Akinori ^a   Isohama, Yoichiro ^a   Shimokawa, Hiroaki ^b   Tsutsui, Masato ^c   Katsuki, Hiroshi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3, 3 BIS (2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; CASPASE 3; CYSTAMINE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; OREXIN; OREXIN A; PROTEIN C FOS; PROTEIN DISULFIDE ISOMERASE; SECURININE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FLUORESCENCE MICROSCOPY; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOUSE; NERVE CELL DEGENERATION; NITROSATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SLEEP DEPRIVATION; SURGICAL TECHNIQUE; WESTERN BLOTTING;

ANIMALS; CELL COUNT; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NADPH DEHYDROGENASE; NERVE DEGENERATION; NEUROPEPTIDES; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROSATION; NITROSO COMPOUNDS; PROTEIN DISULFIDE-ISOMERASES; TIME FACTORS;

EID: 84880813336     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0595-13.2013     Document Type: Article

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