Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H

Journal of General Virology

Volumn 89, Issue 5, 2008, Pages 1184-1191

  Köck, Josef ^a   Blum, Hubert E ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3C; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3H; CELL PROTEIN; CYTOSINE DEAMINASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GUANINE; RNA; VIRUS DNA; APOBEC3C PROTEIN, HUMAN; APOBEC3G PROTEIN, HUMAN; APOBEC3H PROTEIN, HUMAN; CYTIDINE DEAMINASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL STRAIN HEPG2; CHICKEN; CONTROLLED STUDY; GENE AMPLIFICATION; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSFECTION; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; VIRUS GENOME; CELL LINE; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POINT MUTATION;

DNA VIRUSES; HEPATITIS B VIRUS;

BASE SEQUENCE; CELL LINE; CYTIDINE DEAMINASE; CYTOSINE DEAMINASE; DNA, VIRAL; HEPATITIS B VIRUS; HUMANS; MOLECULAR SEQUENCE DATA; POINT MUTATION;

EID: 44649185201     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.83507-0     Document Type: Article

References (28)

1. Baumert, T. F., Rosler, C. Malim, M. H. & von Weizsacker, F. (2007). Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C. Hepatology 46, 682-689.
2. Bonvin, M., Achermann, F., Greeve, I., Stroka, D., Keogh, A., Inderbitzin, D., Candinas, D., Sommer, P., Wain-Hobson, S. & other authors (2006). Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication. Hepatology 43, 1364-1374.
3. Conticello, S. G., Thomas, C. J., Petersen-Mahrt S. K. & Neuberger, M. S. (2005). Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases. Mol Biol Evol 22, 367-377.
4. Cullen, B. R. (2006). Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors. J Virol 80, 1067-1076.
5. Dang, Y., Wang, X., Esselman, W. J. & Zheng, Y. H. (2006). Identification of APOBEC3DE as another antiretroviral factor from the human APOBEC family. J Virol 80, 10522-10533.
6. Ganem, D. & Prince, A. M. (2004). Hepatitis B virus infection - natural history and clinical consequences. N Engl J Med 350, 1118-1129.
7. Gunther, S., Sommer, G., Plikat, U., Iwanska, A., Wain-Hobson, S., Will, H. & Meyerhans, A. (1997). Naturally occurring hepatitis B virus genomes bearing the hallmarks of retroviral G→A hypermutation. Virology 235, 104-108.
8. Harris, R. S. & Liddament, M. T. (2004). Retroviral restriction by APOBEC proteins. Nat Rev Immunol 4, 868-877.
9. Jost S, Turelli, P., Mangeat, B., Protzer, U. & Trono, D. (2007). Induction of antiviral cytidine deaminases does not explain the inhibition of hepatitis B virus replication by interferons. J Virol 81, 10588-10596.
10. Kao, J. H. & Chen, D. S. (2002). Global control of hepatitis B virus infection. Lancet Infect Dis 2, 395-403.
11. KewalRamani, V. N. & Coffin, J. M. (2003). Weapons of mutational destruction. Science 301, 923-925.
12. Nassal, M. (1992). The arginine-rich domain of the hepatitis B virus core protein is required for pregenome encapsidation and productive viral positive-strand DNA synthesis but not for virus assembly. J Virol 66, 4107-4116.
13. Nassal, M. & Schaller, H. (1993). Hepatitis B virus replication. Trends Microbiol 1, 221-228.
14. Nguyen, D. H., Gummuluru, S. & Hu, J. (2007). Deamination-independent inhibition of hepatitis B virus reverse transcription by APOBEC3G. J Virol 81, 4465-4472.
15. Noguchi, C., Ishino, H., Tsuge, M., Fujimoto, Y., Imamura, M., Takahashi, S. & Chayama, K. (2005). G to A hypermutation of hepatitis B virus. Hepatology 41, 626-633.
16. Noguchi, C., Hiraga, N., Mori, N., Tsuge, M., Imamura, M., Takahashi, S, Fujimoto, Y., Ochi, H., Abe, H. & other authors (2007). Dual effect of APOBEC3G on hepatitis B virus. J Gen Virol 88, 432-440.
17. OhAinle, M., Kerns, J. A., Malik H. S. & Emerman, M. (2006). Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H. J Virol 80, 3853-3862.
18. Rosler, C., Kock J., Malim, M. H., Blum, H. E. & von Weizsacker, F. (2004). Comment on "Inhibitioh of hepatitis B virus replication by APOBEC3G". Science 305, 1403 (author reply 1403)..
19. Rosier, C., Kock, J., Kann, M., Malim, M. H., Blum, H. E., Baumert, T. F. & von Weizsacker, F. (2005). APOBEC-mediated interference with hepadnavirus production. Hepatology 42, 301-309.
20. Schlicht, H. J., Radziwill, G. & Schaller, H. (1989). Synthesis and encapsidation of duck hepatitis B virus reverse transcriptase do not require formation of core-polymerase fusion proteins. Cell 56, 85-92.
21. Suspene, R., Guetard, D., Henry, M., Sommer, P., Wain-Hobson, S. & Vartanian, J. P. (2005a). Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo. Proc Natl Acad Sci U S A 102, 8321-8326.
22. Suspene, R., Henry, M., Guillot, S., Wain-Hobson, S. & Vartanian, J. P. (2005b). Recovery of APOBEC3-edited human immunodeficiency virus G→A hypermutants by differential DNA denaturation PCR. J Gen Virol 86, 125-129.
23. Tanaka, Y., Marusawa, H, Seno, H., Matsumoto, Y., Ueda, Y., Kodama, Y., Endo, Y., Yamauchi, J., Matsumoto, T. & other authors (2006). Anti-viral protein APOBEC3G is induced by interferon-α stimulation in human hepatocytes. Biochem Biophys Res Commun 341, 314-319.
24. Turelli, P. & Trono, D. (2005). Editing at the crossroad of innate and adaptive immunity. Science 307, 1061-1065.
25. Turelli, P., Mangeat, B., Jost S., Vianin, S. & Trono, D. (2004). Inhibition of hepatitis B virus replication by APOBEC3G. Science 303, 1829.
26. Wedekind, J. E., Dance, G. S., Sowden, M. P. & Smith, H. C. (2003). Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. Trends Genet 19, 207-216.
27. Wiegand, H. L. & Cullen, B. R. (2007). Inhibition of alpharetrovirus replication by a range of human APOBEC3 proteins. J Virol 81, 13694-13699.
28. Wright, T. L. & Lau, J. Y. (1993). Clinical aspects of hepatitis B virus infection. Lancet 342, 1340-1344.