Antigen specific immunotherapy generates CD27+ CD35+ tolerogenic dendritic cells

Cellular Immunology

Volumn 283, Issue 1-2, 2013, Pages 75-80

  Wu, Zhiqiang ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Antigen specific immunotherapy; B cell; CD27; CD35; Food allergy

Indexed keywords

CD27 ANTIGEN; COMPLEMENT COMPONENT C3B RECEPTOR; DENDRITIC CELL VACCINE; EGG EXTRACT VACCINE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADULT; ANTIGEN SPECIFIC IMMUNOTHERAPY; ARTICLE; B LYMPHOCYTE; BLOOD ANALYSIS; BLOOD SAMPLING; CD4+ CD25+ T LYMPHOCYTE; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; COCULTURE; CONTROLLED STUDY; DENDRITIC CELL; EGG; EGG ALLERGY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOTHERAPY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE;

ANTIGEN SPECIFIC IMMUNOTHERAPY; B CELL; CD27; CD35; FOOD ALLERGY;

ADULT; ANTIGENS, CD27; DENDRITIC CELLS; DESENSITIZATION, IMMUNOLOGIC; FEMALE; FLOW CYTOMETRY; FOOD HYPERSENSITIVITY; HUMANS; IMMUNE TOLERANCE; MALE; MIDDLE AGED; RECEPTORS, COMPLEMENT 3B;

EID: 84880766249     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2013.06.014     Document Type: Article

References (24)

1. Akdis C.A., Akdis M. Mechanisms and treatment of allergic disease in the big picture of regulatory T cells. J. Allergy Clin. Immunol. 2009, 123:735-746.
2. Berin M.C., Mayer L. Can we produce true tolerance in patients with food allergy?. J. Allergy Clin. Immunol. 2013, 131:14-22.
3. Chen X., Song C.H., Feng B.S., Li T.L., Li P., Zheng P.Y., Chen X.M., Xing Z., Yang P.C. Intestinal epithelial cell-derived integrin v6 plays an important role in the induction of regulatory T cells and inhibits an antigen-specific Th2 response. J. Leukoc. Biol. 2011, 90:751-759.
4. He S.H., Chen X., Song C.H., Liu Z.Q., Zhou L.F., Ma W.J., Zhao L.D., Li T.L., Tang S.G., Xing Z., Yang P.C. Interferon-lambda mediates oral tolerance and inhibits antigen-specific, T-helper 2 cell-mediated inflammation in mouse intestine. Gastroenterology 2011, 141:249-258.
5. Illingworth J., Butler N.S., Roetynck S., Mwacharo J., Pierce S.K., Bejon P., Crompton P.D., Marsh K., Ndungu F.M. Chronic exposure to plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion. J. Immunol. 2013, 190:1038-1047.
6. Klinker M.W., Lundy S.K. Multiple mechanisms of immune suppression by B lymphocytes. Mol. Med. 2012, 18:123-137.
7. Kremlitzka M., Polgár A., Fülöp L., Kiss E., Poór G., Erdei A. Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients. Int. Immunol. 2013, 25:25-33.
8. Erdei A., Isaák A., Török K., Sándor N., Kremlitzka M., Prechl J., Bajtay Z. Expression and role of CR1 and CR2 on B and T lymphocytes under physiological and autoimmune conditions. Mol. Immunol. 2009, 46:2767-2773.
9. Kushwah R., Hu J. Role of dendritic cells in the induction of regulatory T cells. Cell Biosci. 2011, 1:20.
10. Kwakkenbos M.J., Diehl S.A., Yasuda E., Bakker A.Q., van Geelen C.M., Lukens M.V., van Bleek G.M., Widjojoatmodjo M.N., Bogers W.M., Mei H., Radbruch A., Scheeren F.A., Spits H., Beaumont T. Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming. Nat. Med. 2010, 16:123-128.
11. Lee S.J., Noh G., Lee J.H. In vitro induction of allergen-specific interleukin-10-producing regulatory B cell responses by interferon-gamma in non-immunoglobulin E-mediated milk allergy. Allergy Asthma Immunol. Res. 2013, 5:48-54.
12. Leggat D.J., Thompson R.S., Khaskhely N.M., Iyer A.S., Westerink M.A.J. The immune response to pneumococcal polysaccharides 14 and 23F among elderly individuals consists predominantly of switched memory B cells. J. Infect. Dis. 2013, 208:101-108.
13. Lewis K.L., Reizis B. Dendritic cells: arbiters of immunity and immunological tolerance. Cold Spring Harb. Perspect. Biol. 2012, 4.
14. Li G., Abediankenari S., Kim Y.J., Campbell T.B., Ito S., Graham-Evans B., Cooper S., Broxmeyer H.E. TGF-beta combined with M-CSF and IL-4 induces generation of immune inhibitory cord blood dendritic cells capable of enhancing cytokine-induced ex vivo expansion of myeloid progenitors. Blood 2007, 110:2872-2879.
15. Liu W.H., Liu J.J., Wu J., Zhang L.L., Liu F., Yin L., Zhang M.M., Yu B. Novel mechanism of inhibition of dendritic cells maturation by mesenchymal stem cells via interleukin-10 and the JAK1/STAT3 signaling pathway. PLoS One 2013, 8:e55487.
16. Prodeus A.P., Goerg S., Shen L.M., Pozdnyakova O.O., Chu L., Alicot E.M., Goodnow C.C., Carroll M.C. A critical role for complement in maintenance of self-tolerance. Immunity 1998, 9:721-731.
17. Qiu S., Du Y., Duan X., Geng X., Xie J., Gao H., Yang P.C. B cell immunity in allergic nasal mucosa induces T helper 2 cell differentiation. J. Clin. Immunol. 2012, 32:886-895.
18. Santos A.F., Lack G. Food allergy and anaphylaxis in pediatrics: update 2010-2012. Pediatr. Allergy Immunol. 2012, 23:698-706.
19. Shamji M.H., Durham S.R. Mechanisms of immunotherapy to aeroallergens. Clin. Exp. Allergy 2011, 41:1235-1246.
20. Shulzhenko N., Morgun A., Hsiao W., Battle M., Yao M., Gavrilova O., Orandle M., Mayer L., Macpherson A.J., McCoy K.D., Fraser-Liggett C., Matzinger P. Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut. Nat. Med. 2011, 17:1585-1593.
21. Sicherer S.H., Leung D.Y.M. Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in. J. Allergy Clin. Immunol. 2012, 131(2013):55-66.
22. Valenta R., Campana R., Marth K., van Hage M. Allergen-specific immunotherapy: from therapeutic vaccines to prophylactic approaches. J. Intern. Med. 2012, 272:144-157.
23. Verhagen J., Blaser K., Akdis C.A., Akdis M. Mechanisms of allergen-specific immunotherapy: T-regulatory cells and more. Immunol. Allergy Clin. North Am. 2006, 26:207-231.
24. Zimmer A., Bouley J., Le Mignon M., Pliquet E., Horiot S.p., Turfkruyer M., Baron-Bodo V., Horak F., Nony E., Louise A., Moussu H., Mascarell L., Moingeon P. A regulatory dendritic cell signature correlates with the clinical efficacy of allergen-specific sublingual immunotherapy. J. Allergy Clin. Immunol. 2012, 129:1020-1030.