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Volumn 8, Issue 6, 2013, Pages

Comparison of two methods for measuring γ-H2AX nuclear fluorescence as a marker of DNA damage in cultured human cells: Applications for microbeam radiation therapy

Author keywords

H2AX foci; microbeam; Radiation damage evaluation methods; Radiotherapy concepts

Indexed keywords

DAMAGE EVALUATION; FLUORESCENCE INTENSITY MEASUREMENT; H2AX FOCI; IMMUNOFLUORESCENCE ASSAY; MICRO BEAMS; MICROBEAM RADIATION THERAPY; NORMAL TISSUE SPARING; NORMAL-TISSUE TOXICITY;

EID: 84880708331     PISSN: None     EISSN: 17480221     Source Type: Journal    
DOI: 10.1088/1748-0221/8/06/C06008     Document Type: Article
Times cited : (9)

References (33)
  • 1
    • 77952098070 scopus 로고    scopus 로고
    • Effects of pulsed, spatially fractionated, microscopic synchrotron X-ray beams on normal and tumoral brain tissue
    • 10.1016/j.mrrev.2009.12.003 0027-5107
    • E. Brauer-Krisch et al. 2010 Effects of pulsed, spatially fractionated, microscopic synchrotron X-ray beams on normal and tumoral brain tissue, Mutat. Res. 704 160
    • (2010) Mutat. Res. , vol.704 , pp. 160
    • Brauer-Krisch, E.1
  • 3
    • 0029068507 scopus 로고
    • Subacute neuropathological effects of microplanar beams of x-rays from a synchrotron wiggler
    • 10.1073/pnas.92.19.8783 0027-8424
    • D.N. Slatkin, P. Spanne, F.A. Dilmanian, J.O. Gebbers, and J.A. Laissue 1995 Subacute neuropathological effects of microplanar beams of x-rays from a synchrotron wiggler, Proc. Natl. Acad. Sci. USA 92 8783
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8783
    • Slatkin, D.N.1    Spanne, P.2    Dilmanian, F.A.3    Gebbers, J.O.4    Laissue, J.A.5
  • 4
    • 19244384949 scopus 로고    scopus 로고
    • Neuropathology of ablation of rat gliosarcomas and contiguous brain tissues using a microplanar beam of synchrotron-wiggler-generated x rays
    • 10.1002/(SICI)1097-0215(199 81123)78:5<654::AID-I JC21>3.0.CO;2-L
    • J.A. Laissue et al. 1998 Neuropathology of ablation of rat gliosarcomas and contiguous brain tissues using a microplanar beam of synchrotron-wiggler- generated x rays, Int. J. Cancer 78 654
    • (1998) Int. J. Cancer , vol.78 , pp. 654
    • Laissue, J.A.1
  • 5
    • 33748294454 scopus 로고    scopus 로고
    • Determination of dosimetrical quantities used in microbeam radiation therapy (MRT) with Monte Carlo simulations
    • DOI 10.1118/1.2229422
    • E.A. Siegbahn, J. Stepanek, E. Brauer-Krisch and A. Bravin 2006 Determination of dosimetrical quantities used in microbeam radiation therapy (MRT) with Monte Carlo simulations, Med. Phys. 33 3248 (Pubitemid 44327427)
    • (2006) Medical Physics , vol.33 , Issue.9 , pp. 3248-3259
    • Siegbahn, E.A.1    Stepanek, J.2    Brauer-Krisen, E.3    Bravin, A.4
  • 6
    • 0033318577 scopus 로고    scopus 로고
    • Microbeam radiation therapy
    • 10.1117/12.368185
    • J.A. Laissue et al. 1999 Microbeam radiation therapy, Proc. SPIE 3770 38
    • (1999) Proc. SPIE , vol.3770 , pp. 38
    • Laissue, J.A.1
  • 8
    • 0041302189 scopus 로고    scopus 로고
    • Response of rat skin to high-dose unidirectional x-ray microbeams: A histological study
    • 10.1667/3033 0033-7587
    • N. Zhong, G.M. Morris, T. Bacarian, E.M. Rosen and F.A. Dilmanian 2003 Response of rat skin to high-dose unidirectional x-ray microbeams: a histological study, Radiat. Res. 160 133
    • (2003) Radiat. Res. , vol.160 , pp. 133
    • Zhong, N.1    Morris, G.M.2    Bacarian, T.3    Rosen, E.M.4    Dilmanian, F.A.5
  • 9
    • 18344393248 scopus 로고    scopus 로고
    • Response of rat intracranial 9L gliosarcoma to microbeam radiation therapy
    • F.A. Dilmanian et al. 2002 Response of rat intracranial 9L gliosarcoma to microbeam radiation therapy, Neuro-oncology 4 26
    • (2002) Neuro-oncology , vol.4 , pp. 26
    • Dilmanian, F.A.1
  • 13
    • 71049166023 scopus 로고    scopus 로고
    • Synchrotron microbeam radiation therapy for rat brain tumor palliation - Influence of the microbeam width at constant valley dose
    • 10.1088/0031-9155/54/21/017 0031-9155 017
    • R. Serduc et al. 2009 Synchrotron microbeam radiation therapy for rat brain tumor palliation - influence of the microbeam width at constant valley dose, Phys. Med. Biol. 54 6711
    • (2009) Phys. Med. Biol. , vol.54 , Issue.21 , pp. 6711
    • Serduc, R.1
  • 14
    • 34547470601 scopus 로고    scopus 로고
    • Prospects for microbeam radiation therapy of brain tumours in children to reduce neurological sequelae
    • DOI 10.1111/j.1469-8749.2007.00577.x
    • J.A. Laissue, H. Blattmann, H.. Wagner, M.A. Grotzer and D.N. Slatkin 2007 Prospects for microbeam radiation therapy of brain tumours in children to reduce neurological sequelae, Dev. Med. Child Neurol. 49 577 (Pubitemid 47161847)
    • (2007) Developmental Medicine and Child Neurology , vol.49 , Issue.8 , pp. 577-581
    • Laissue, J.A.1    Blattmann, H.2    Wagner, H.P.3    Grotzer, M.A.4    Slatkin, D.N.5
  • 16
    • 33645354036 scopus 로고    scopus 로고
    • In vivo two-photon microscopy study of short-term effects of microbeam irradiation on normal mouse brain microvasculature
    • 10.1016/j.ijrobp.2005.11.047 0360-3016
    • R. Serduc et al. 2006 In vivo two-photon microscopy study of short-term effects of microbeam irradiation on normal mouse brain microvasculature, Int. J. Radiat. Oncol. Biol. Phys. 64 1519
    • (2006) Int. J. Radiat. Oncol. Biol. Phys. , vol.64 , pp. 1519
    • Serduc, R.1
  • 17
    • 77952572348 scopus 로고    scopus 로고
    • Tumor cell response to synchrotron microbeam radiation therapy differs markedly from cells in normal tissues
    • 10.1016/j.ijrobp.2010.01.035 0360-3016
    • J.C. Crosbie et al. 2010 Tumor cell response to synchrotron microbeam radiation therapy differs markedly from cells in normal tissues, Int. J. Radiat. Oncol. Biol. Phys. 77 886
    • (2010) Int. J. Radiat. Oncol. Biol. Phys. , vol.77 , pp. 886
    • Crosbie, J.C.1
  • 19
    • 3242880238 scopus 로고    scopus 로고
    • H2AX: The histone guardian of the genome
    • DOI 10.1016/j.dnarep.2004.03.024, PII S1568786404000837
    • O. Ferandez-Capetillo, A. Lee, M. Nussenzweig and A. Nussenzweig 2004 H2AX: The histone guardian of the genome, DNA Repair 3 959 (Pubitemid 38997938)
    • (2004) DNA Repair , vol.3 , Issue.8-9 , pp. 959-967
    • Fernandez-Capetillo, O.1    Lee, A.2    Nussenzweig, M.3    Nussenzweig, A.4
  • 20
    • 70350304614 scopus 로고    scopus 로고
    • γ-H2AX as a protein biomarker for radiation exposure
    • K. Rothkamm and S. Horn 2009 γ-H2AX as a protein biomarker for radiation exposure, Ann. Ist. Super. Sanità 45 265
    • (2009) Ann. Ist. Super. Sanità , vol.45 , pp. 265
    • Rothkamm, K.1    Horn, S.2
  • 23
    • 33751171564 scopus 로고    scopus 로고
    • Relationship between DNA double-strand break rejoining and cell survival after exposure to ionizing radiation in human fibroblast strains with differing ATM/p53 status: Implications for evaluation of clinical radiosensitivity
    • 10.1016/j.ijrobp.2006.08.064 0360-3016
    • R. Mirzayans, D. Severin and D. Murray 2006 Relationship between DNA double-strand break rejoining and cell survival after exposure to ionizing radiation in human fibroblast strains with differing ATM/p53 status: implications for evaluation of clinical radiosensitivity, Int. J. Radiat. Oncol. Biol. Phys. 66 1498
    • (2006) Int. J. Radiat. Oncol. Biol. Phys. , vol.66 , pp. 1498
    • Mirzayans, R.1    Severin, D.2    Murray, D.3
  • 24
    • 84855447566 scopus 로고    scopus 로고
    • In situ biological dose mapping estimates the radiation burden delivered to 'spared' tissue between synchrotron x-ray microbeam radiation therapy tracks
    • 10.1371/journal.pone.0029853
    • K. Rothkamm et al. 2012 In situ biological dose mapping estimates the radiation burden delivered to 'spared' tissue between synchrotron x-ray microbeam radiation therapy tracks, PLoS ONE 7 e29853
    • (2012) PLoS ONE , vol.7
    • Rothkamm, K.1
  • 25
    • 29644443047 scopus 로고    scopus 로고
    • Computational methods for analysis of foci: Validation for radiation-induced γ-H2AX foci in human cells
    • DOI 10.1667/RR3486.1
    • W. Böcker and G. Iliakis 2006 Computational methods for analysis of foci: Validation for radiation-induced γ-H2AX foci in human cells, Radiat. Res. 165 113 (Pubitemid 43023331)
    • (2006) Radiation Research , vol.165 , Issue.1 , pp. 113-124
    • Bocker, W.1    Iliakis, G.2
  • 27
    • 39749184636 scopus 로고    scopus 로고
    • Biochemical kinetics model of DSB repair and induction of γ-H2AX foci by non-homologous end joining
    • DOI 10.1667/RR1035.1
    • F.A. Cucinotta, J.M. Pluth, J.A. Anderson, J.V. Harper and P. O'Neill 2008 Biochemical kinetics model of DSB repair and induction of γ-H2AX foci by non-homologous end joining, Radiat. Res. 169 214 (Pubitemid 351295079)
    • (2008) Radiation Research , vol.169 , Issue.2 , pp. 214-222
    • Cucinotta, F.A.1    Pluth, J.M.2    Anderson, J.A.3    Harper, J.V.4    O'Neill, P.5
  • 28
    • 61849145731 scopus 로고    scopus 로고
    • Development of an automated γ-H2AX immunocytochemistry assay
    • 10.1667/RR1349.1 0033-7587
    • Y.N. Hou et al. 2009 Development of an automated γ-H2AX immunocytochemistry assay, Radiat. Res. 171 360
    • (2009) Radiat. Res. , vol.171 , pp. 360
    • Hou, Y.N.1
  • 29
    • 67449088381 scopus 로고    scopus 로고
    • Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software
    • 10.1080/09553000902748757
    • Z. Cai, K.A. Vallis and R.M. Reilly 2009 Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software, Int. J. Radiat. Biol. 85 262
    • (2009) Int. J. Radiat. Biol. , vol.85 , pp. 262
    • Cai, Z.1    Vallis, K.A.2    Reilly, R.M.3
  • 30
    • 0035512271 scopus 로고    scopus 로고
    • SPECTRA: A synchrotron radiation calculation code
    • DOI 10.1107/S090904950101425X
    • T. Tanaka and H. Kitamura 2001 SPECTRA: a synchrotron radiation calculation code, J. Synchrotron Radiat. 8 1221 (Pubitemid 33576470)
    • (2001) Journal of Synchrotron Radiation , vol.8 , Issue.6 , pp. 1221-1228
    • Tanaka, T.1    Kitamura, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.