Brain tumor vessel response to synchrotron microbeam radiation therapy: A short-term in vivo study

Physics in Medicine and Biology

Volumn 53, Issue 13, 2008, Pages 3609-3622

  Serduc, Raphaël ^a,b,d,e   Christen, Thomas ^a,b   Laissue, Jean ^c   Farion, Régine ^a,b   Bouchet, Audrey ^a,b   Sanden, Boudewijn Van Der ^a,b   Segebarth, Christoph ^a,b   Bräuer Krisch, Elke ^d   Le Duc, Géraldine ^d   Bravin, Alberto ^d   Rémy, Chantal ^a,b   Barbier, Emmanuel L ^a,b  

^a GRENOBLE INSTITUT DES NEUROSCIENCES   (France)

^b UNIV GRENOBLE ALPES   (France)

^c UNIVERSITY OF BERN   (Switzerland)

^d EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^e UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APPARENT DIFFUSION COEFFICIENT (ADC); BLOOD VOLUME (BV); BRAIN TUMOR MODEL; BRAIN TUMORS; IN VIVO STUDIES; LOG-RANK TEST; MAGNETIC RESONANCE IMAGING (MRI); MICRO-BEAMS; MICROBEAM RADIATION THERAPY (MRT); NUDE MICE; ORTHOGONAL ARRAYS (OA); SURVIVAL TIME; VASCULATURE; VESSEL SIZE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL DIAMETER; BLOOD VOLUME; BRAIN TUMOR; CANCER SURVIVAL; CANCER TRANSPLANTATION; CONTROLLED STUDY; DIFFUSION COEFFICIENT; GLIOSARCOMA; HISTOPATHOLOGY; IMMUNOHISTOLOGY; IN VIVO STUDY; INOCULATION; IRRADIATION; LOG RANK TEST; MICROBEAM RADIATION THERAPY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RADIATION DOSE; RADIOTHERAPY; SURVIVAL TIME; SYNCHROTRON RADIATION; TREATMENT RESPONSE; TUMOR GROWTH; TUMOR VASCULARIZATION; TUMOR VOLUME;

ANIMALS; BRAIN NEOPLASMS; GLIOSARCOMA; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; RADIOTHERAPY; RADIOTHERAPY DOSAGE; SURVIVAL RATE; SYNCHROTRONS; TIME FACTORS; TREATMENT OUTCOME;

EID: 47649109950     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/53/13/015     Document Type: Article

References (53)

1. Barth R F 1998 Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas J. Neurooncol. 36 91-102
2. Benda P, Someda K, Messer J and Sweet W H 1971 Morphological and immunochemical studies of rat glial tumors and clonal strains propagated in culture J. Neurosurg. 34 310-23
3. Brauer E 2005 Theoretical and experimental microdosimetry for MRT (Microbeam Radiation Therapy) Micro and Mini Dosimetry (Melbourne, Australia)
4. Brauer E, Siegbahn E A, Zhang L, Stepanek J, Blattmann H, Slatkin D N, Gebbers J O, Jasmin M, Laissue J and Bravin A 2005 Characterization of a tungsten/gas multislit collimator for microbeam radiation therapy at the European synchrotron radiation facility Rev. Sci. Instrum. 76 1-7
5. Brauer-Krisch E, Bravin A, Lerch M, Rosenfeld A, Stepanek J, Di Michiel M and Laissue J A 2003 MOSFET dosimetry for microbeam radiation therapy at the European Synchrotron Radiation Facility Med. Phys. 30 583-9
6. Brauer-Krisch E, Requardt H, Regnard P, Corde S, Siegbahn E, Leduc G, Brochard T, Blattmann H, Laissue J and Bravin A 2005 New irradiation geometry for microbeam radiation therapy Phys. Med. Biol. 50 3103-11
7. Coderre J A, Button T M, Micca P L, Fisher C D, Nawrocky M M and Liu H B 1994 Neutron capture therapy of the 9L rat gliosarcoma using the p-boronophenylalanine-fructose complex Int. J. Radiat. Oncol. Biol. Phys. 30 643-52
8. De Felici M, Felici R, Sanchez del Rio M, Ferrero C, Bacarian T and Dilmanian F A 2005 Dose distribution from x-ray microbeam arrays applied to radiation therapy: an EGS4 Monte Carlo study Med. Phys. 32 2455-63
9. Dilmanian F A et al 2001 Response of avian embryonic brain to spatially segmented x-ray microbeams Cell Mol. Biol. 47 485-93
10. Dilmanian F A et al 2002 Response of rat intracranial 9L gliosarcoma to microbeam radiation therapy Neuro-oncol 4 26-38
11. Dilmanian F A, Hainfeld J F, Kruse C A, Cool C D, Sze C I, Laterra J S, Feldman A, Gatley S J, Nawrocky M M and Yakupov R 2003a Biological mechanisms underlying the X-ray microbeam effects of preferentially destroying tumors National Synchrotron Light Source Activity Report 2002 ed M A Corwin and S N Ehrlich available at: http://nslsweb.nsls.bnl.gov/nsls/pubs/actrpt/2002/ Abstracts/dilm0599.pdf
12. Dilmanian F A, Morris G M, Zhong N, Bacarian T, Hainfeld J F, Kalef-Ezra J, Brewington L J, Tammam J and Rosen E M 2003b Murine EMT-6 carcinoma: high therapeutic efficacy of microbeam radiation therapy Radiat. Res. 159 632-41
13. Dilmanian F A, Zhong Z, Bacarian T, Benveniste H, Romanelli P, Wang R, Welwart J, Yuasa T, Rosen E M and Anschel D J 2006 Interlaced x-ray microplanar beams: a radiosurgery approach with clinical potential Proc. Natl Acad. Sci. USA 103 9709-14
14. Gaber M W, Yuan H, Killmar J T, Naimark M D, Kiani M F and Merchant T E 2004 An intravital microscopy study of radiation-induced changes in permeability and leukocyte-endothelial cell interactions in the microvessels of the rat pia mater and cremaster muscle Brain Res. Brain Res. Protoc. 13 1-10
15. Heckmann M, Douwes K, Peter R and Degitz K 1998 Vascular activation of adhesion molecule mRNA and cell surface expression by ionizing radiation Exp. Cell Res. 238 148-54
16. Hillman G G, Slos P, Wang Y, Wright J L, Layer A, De Meyer M, Yudelev M, Che M and Forman J D 2004 Tumor irradiation followed by intratumoral cytokine gene therapy for murine renal adenocarcinoma Cancer Gene Ther. 11 61-72
17. Ito J, Marmarou A, Barzo P, Fatouros P and Corwin F 1996 Characterization of edema by diffusion-weighted imaging in experimental traumatic brain injury J. Neurosurg. 84 97-103
18. Jain R K 2003 Molecular regulation of vessel maturation Nature 9 685-93
19. Kim J H, Khil M S, Kolozsvary A, Gutierrez J A and Brown S L 1999 Fractionated radiosurgery for 9L gliosarcoma in the rat brain Int. J. Radiat. Oncol. Biol. Phys. 45 1035-40
20. Kulprathipanja N V and Kruse C A 2004 Microglia phagocytose alloreactive CTL-damaged 9L gliosarcoma cells J. Neuroimmunol. 153 76-82
21. Laissue J 2003 Preclinical Microbeam radiation therapy (MRT): concepts experiments Medical Application Workshop (Melbourne, Australia)
22. Laissue J A et al 1999 Microbeam radiation therapy Proc. SPIE 3770 38-45
23. Laissue J A et al 2001 The weanling piglet cerebellum: a surrogate for tolerance to MRT (microbeam radiation therapy) in pediatric neuro-oncology Proc. SPIE 4508 65-73
24. Laissue J A, Blattmann H, Wagner H P, Grotzer M A and Slatkin D N 2007 Prospects for microbeam radiation therapy of brain tumours in children to reduce neurological sequelae Dev. Med. Child. Neurol. 49 577-81
25. Laissue J A et al 1998 Neuropathology of ablation of rat gliosarcomas and contiguous brain tissues using a microplanar beam of synchrotron-wiggler- generated X rays Int. J. Cancer 78 654-60
26. Lambert L E and Paulnock D M 1987 Modulation of macrophage function by gamma-irradiation. Acquisition of the primed cell intermediate stage of the macrophage tumoricidal activation pathway J. Immunol. 139 2834-41
27. Mariani C L, Kouri J G and Streit W J 2006 Rejection of RG-2 gliomas is mediated by microglia and T lymphocytes J. Neurooncol. 79 243-53
28. Marmarou A, Portella G, Barzò P, Signoretti S, Fatouros P, Beaumont A, Jiang T and Bullock R 2000 Distinguishing between cellular and vasogenic edema in head-injured patients with focal lesions using MRI Acta Neurochir. Suppl. 76 349-51
29. Miura M, Blattmann H, Brauer-Krisch E, Bravin A, Hanson A L, Nawrocky M M, Micca P L, Slatkin D N and Laissue J A 2006 Radiosurgical palliation of aggressive murine SCCVII squamous cell carcinomas using synchrotron-generated X-ray microbeams Br. J. Radiol. 79 71-5
30. Morris G M, Coderre J A, Micca P L, Lombardo D T and Hopewell J W 2000 Boron neutron capture therapy of the rat 9L gliosarcoma: evaluation of the effects of shark cartilage Br. J. Radiol. 73 429-34
31. Regnard P 2004 Thérapie par microfaisceaux appliquée à la pathologie tumorale cérébrale chez le rat Veterinarian Thesis Université Claude Bernard, Lyon I, France 150 pp
32. Regnard P et al 2008 Irradiation of intracerebral 9L gliosarcoma by a single array of microplanar x-ray beams from a synchrotron: balance between curing and sparing Phys. Med. Biol. 53 861-78
33. Regnard P, Le Duc G, Brauer E, Clair C, Kusak A, Dallery D, Tropres I, Lamalle L, Laissue J and Bravin A 2004 Microbeam radiation therapy applied to rat's brain tumor: finding the best compromise between normal tissue sparing and tumor curing ESRF User Meeting (Grenoble)
34. Salvat F, Fernandez-Varea J M and Sempau J 2003 PENELOPE. A code system for Monte Carlo simulation of lectron and photon transport OECD Nuclear Energy Agency Issyles-Moulineaux-France (available in PDF format at www.nea.fr)
35. Serduc R 2006 Effets de la radiothérapie par microfaisceaux sur la microvascularisation saine et tumorale chez la souris PhD Thesis University Joseph Fourier, Grenoble, France 243 pp
36. Serduc R et al 2006 In vivo two-photon microscopy study of short-term effects of microbeam irradiation on normal mouse brain microvasculature Int. J. Radiat. Oncol. Biol. Phys. 64 1519-27
37. Serduc R et al 2008 Characterization and quantification of cerebral edema induced by synchrotron x-ray microbeam radiation therapy Phys. Med. Biol. 53 1153-66
38. Shah M R and Ramsey W J 2003 CD8+ T-cell mediated anti-tumor responses cross-reacting against 9L and RT2 rat glioma cell lines Cell Immunol. 225 113-21
39. Siegbahn E, Brauer-Krisch E, Stepanek J, Blattmann H, Laissue J and Bravin A 2005 Dosimetric studies of microbeam radiation therapy (MRT) with Monte Carlo simulations Nucl. Instrum. Methods Phys. Res. A 548 54-8
40. Siegbahn E A, Stepanek J, Bräuer-Krisch E and Bravin A 2006 Determination of dosimetrical quantities used in microbeam radiation therapy (MRT) with Monte Carlo simulations Med. Phys. 33 3248-59
41. Slatkin D N, Spanne P, Dilmanian F A, Gebbers J O and Laissue J A 1995 Subacute neuropathological effects of microplanar beams of x-rays from a synchrotron wiggler Proc. Natl Acad. Sci. USA 92 8783-7
42. Slatkin D N, Spanne P, Dilmanian F A and Sandborg M 1992 Microbeam radiation therapy Med. Phys. 19 1395-400
43. Smilowitz H M et al 2006 Synergy of gene-mediated immunoprophylaxis and microbeam radiation therapy for advanced intracerebral rat 9L gliosarcomas J. Neurooncol. 78 135-43
44. Smilowitz H M, Coderre J A, Nawrocky M M, Tu W, Pinkerton A, Jahng G H, Gebbers N and Slatkin D N 2002 The combination of X-ray-mediated radiosurgery and gene-mediated immunoprophylaxis for advanced intracerebral gliosarcomas in rats J. Neurooncol. 57 9-18
45. Smilowitz H M, Micca P L, Nawrocky M M, Slatkin D N, Tu W and Coderre J A 2000 The combination of boron neutron-capture therapy and immunoprophylaxis for advanced intracerebral gliosarcomas in rats J. Neurooncol. 46 231-40
46. Smyth M J, Cretney E, Kershaw M H and Hayakawa Y 2004 Cytokines in cancer immunity and immunotherapy Immunol. Rev. 202 275-93
47. Tropres I, Grimault S, Vaeth A, Grillon E, Julien C, Payen J F, Lamalle L and Decorps M 2001 Vessel size imaging Magn. Reson. Med. 45 397-408
48. Tropres I, Lamalle L, Peoc'h M, Farion R, Usson Y, Decorps M and Remy C 2004 In vivo assessment of tumoral angiogenesis Magn. Reson. Med. 51 533-41
49. Valable S, Lemasson B, Farion R, Beaumont M, Segebarth C, Remy C and Barbier E L 2008 Assessment of blood volume, vessel size and the expression of angiogenic factors in two rat glioma models: a longitudinal in vivo and ex vivo study NMR Biomed. accepted
50. Wang Y, Xu M, Che M, Von Hofe E, Abbas A, Kallinteris N L, Lu X, Liss Z J, Forman J D and Hillman G G 2005 Curative antitumor immune response is optimal with tumor irradiation followed by genetic induction of major histocompatibility complex class I and class II molecules and suppression of Ii protein Hum. Gene Ther. 16 187-99
51. Yuan H, Gaber M W, McColgan T, Naimark M D, Kiani M F and Merchant T E 2003 Radiation-induced permeability and leukocyte adhesion in the rat blood-brain barrier: modulation with anti-ICAM-1 antibodies Brain Res. 969 59-69
52. Zeman W, Curtis H and Baker C 1961 Histopathologic effect of high-energy-particle microbeams on the visual cortex of the mouse brain Radiat. Res. 15 496-514
53. Zhong N, Morris G M, Bacarian T, Rosen E M and Dilmanian F A 2003 Response of rat skin to high-dose unidirectional x-ray microbeams: a histological study Radiat. Res. 160 133-42