-
1
-
-
84858964582
-
Analysis of uterine gene expression in interleukin-15 knockout mice reveals uterine natural killer cells do not play a major role in decidualization and associated angiogenesis
-
22187674 10.1530/REP-11-0325 1:CAS:528:DC%2BC38XlvFOqsLc%3D
-
Bany, B.M., Scott, C.A., and Eckstrum, K.S. (2012). Analysis of uterine gene expression in interleukin-15 knockout mice reveals uterine natural killer cells do not play a major role in decidualization and associated angiogenesis. Reproduction 143, 359-375.
-
(2012)
Reproduction
, vol.143
, pp. 359-375
-
-
Bany, B.M.1
Scott, C.A.2
Eckstrum, K.S.3
-
2
-
-
0032535177
-
C-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets
-
9869632 10.1101/gad.12.24.3797 1:CAS:528:DyaK1MXmtFGjtA%3D%3D
-
Bush, A., Mateyak, M., Dugan, K., Obaya, A., Adachi, S., Sedivy, J., and Cole, M. (1998). c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets. Genes Dev. 12, 3797-3802.
-
(1998)
Genes Dev.
, vol.12
, pp. 3797-3802
-
-
Bush, A.1
Mateyak, M.2
Dugan, K.3
Obaya, A.4
Adachi, S.5
Sedivy, J.6
Cole, M.7
-
3
-
-
77949769388
-
O-linked beta-Nacetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress
-
19647786 10.1016/j.bbagen.2009.07.018 1:CAS:528:DC%2BC3cXotVWitQ%3D%3D
-
Butkinaree, C., Park, K., and Hart, G.W. (2010). O-linked beta-Nacetylglucosamine (O-GlcNAc): extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress. Biochim. Biophys. Acta 1800, 96-106.
-
(2010)
Biochim. Biophys. Acta
, vol.1800
, pp. 96-106
-
-
Butkinaree, C.1
Park, K.2
Hart, G.W.3
-
4
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
18337823 10.1038/nature06734 1:CAS:528:DC%2BD1cXjt1Gnu74%3D
-
Christofk, H.R., Vander Heiden, M.G., Harris, M.H., Ramanathan, A., Gerszten, R.E., Wei, R., Fleming, M.D., Schreiber, S.L., and Cantley, L.C. (2008a). The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 452, 230-233.
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
5
-
-
40749099894
-
Pyruvate kinase M2 is a phosphotyrosine-binding protein
-
18337815 10.1038/nature06667 1:CAS:528:DC%2BD1cXjt1Gnu7k%3D
-
Christofk, H.R., Vander Heiden, M.G., Wu, N., Asara, J.M., and Cantley, L.C. (2008b). Pyruvate kinase M2 is a phosphotyrosine-binding protein. Nature 452, 181-186.
-
(2008)
Nature
, vol.452
, pp. 181-186
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Wu, N.3
Asara, J.M.4
Cantley, L.C.5
-
6
-
-
84861975431
-
Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis
-
22349059 10.1016/j.semcdb.2012.02.002 1:CAS:528:DC%2BC38XosFShu7g%3D
-
Daye, D., and Wellen, K.E. (2012). Metabolic reprogramming in cancer: unraveling the role of glutamine in tumorigenesis. Semin. Cell Dev. Biol. 23, 362-369.
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 362-369
-
-
Daye, D.1
Wellen, K.E.2
-
7
-
-
64749116346
-
C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
-
19219026 10.1038/nature07823 1:CAS:528:DC%2BD1MXhvFKjtrY%3D
-
Gao, P., Tchernyshyov, I., Chang, T.C., Lee, Y.S., Kita, K., Ochi, T., Zeller, K.I., De Marzo, A.M., Van Eyk, J.E., Mendell, J.T., et al. (2009). c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature 458, 762-765.
-
(2009)
Nature
, vol.458
, pp. 762-765
-
-
Gao, P.1
Tchernyshyov, I.2
Chang, T.C.3
Lee, Y.S.4
Kita, K.5
Ochi, T.6
Zeller, K.I.7
De Marzo, A.M.8
Van Eyk, J.E.9
Mendell, J.T.10
-
8
-
-
77949295164
-
The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine
-
19647043 10.1016/j.bbagen.2009.07.017 1:CAS:528:DC%2BC3cXotVWitw%3D%3D
-
Hanover, J.A., Krause, M.W., and Love, D.C. (2010). The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine. Biochim. Biophys. Acta 1800, 80-95.
-
(2010)
Biochim. Biophys. Acta
, vol.1800
, pp. 80-95
-
-
Hanover, J.A.1
Krause, M.W.2
Love, D.C.3
-
9
-
-
77449131347
-
Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth
-
19920251 10.1126/scisignal.2000431
-
Hitosugi, T., Kang, S., Vander Heiden, M.G., Chung, T.W., Elf, S., Lythgoe, K., Dong, S., Lonial, S., Wang, X., Chen, G.Z., et al. (2009). Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth. Sci. Signal. 2, ra73.
-
(2009)
Sci. Signal.
, vol.2
, pp. 73
-
-
Hitosugi, T.1
Kang, S.2
Vander Heiden, M.G.3
Chung, T.W.4
Elf, S.5
Lythgoe, K.6
Dong, S.7
Lonial, S.8
Wang, X.9
Chen, G.Z.10
-
10
-
-
67349127497
-
Role of FOXA in mitochondrial citrate carrier gene expression and insulin secretion
-
19445897 10.1016/j.bbrc.2009.05.030 1:CAS:528:DC%2BD1MXntVGmtLo%3D
-
Iacobazzi, V., Infantino, V., Bisaccia, F., Castegna, A., and Palmieri, F. (2009). Role of FOXA in mitochondrial citrate carrier gene expression and insulin secretion. Biochem. Biophys. Res. Commun. 385, 220-224.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.385
, pp. 220-224
-
-
Iacobazzi, V.1
Infantino, V.2
Bisaccia, F.3
Castegna, A.4
Palmieri, F.5
-
11
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
16517405 10.1016/j.cmet.2006.02.002
-
Kim, J.W., Tchernyshyov, I., Semenza, G.L., and Dang, C.V. (2006). HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 3, 177-185.
-
(2006)
Cell Metab.
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
12
-
-
84855453655
-
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells
-
22225880 10.1016/j.cmet.2011.12.009 1:CAS:528:DC%2BC38XkvF2nsg%3D%3D
-
Le, A., Lane, A.N., Hamaker, M., Bose, S., Gouw, A., Barbi, J., Tsukamoto, T., Rojas, C.J., Slusher, B.S., Zhang, H., et al. (2012). Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Cell Metab. 15, 110-121.
-
(2012)
Cell Metab.
, vol.15
, pp. 110-121
-
-
Le, A.1
Lane, A.N.2
Hamaker, M.3
Bose, S.4
Gouw, A.5
Barbi, J.6
Tsukamoto, T.7
Rojas, C.J.8
Slusher, B.S.9
Zhang, H.10
-
13
-
-
79957567239
-
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
-
21620138 10.1016/j.cell.2011.03.054 1:CAS:528:DC%2BC3MXmvFWhtL0%3D
-
Luo, W., Hu, H., Chang, R., Zhong, J., Knabel, M., O'Meally, R., Cole, R.N., Pandey, A., and Semenza, G.L. (2011). Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell 145, 732-744.
-
(2011)
Cell
, vol.145
, pp. 732-744
-
-
Luo, W.1
Hu, H.2
Chang, R.3
Zhong, J.4
Knabel, M.5
O'Meally, R.6
Cole, R.N.7
Pandey, A.8
Semenza, G.L.9
-
14
-
-
23044500915
-
Pyruvate kinase type M2 and its role in tumor growth and spreading
-
15908230 10.1016/j.semcancer.2005.04.009 1:CAS:528:DC%2BD2MXmvVKntbw%3D
-
Mazurek, S., Boschek, C.B., Hugo, F., and Eigenbrodt, E. (2005). Pyruvate kinase type M2 and its role in tumor growth and spreading. Semin. Cancer Biol. 15, 300-308.
-
(2005)
Semin. Cancer Biol.
, vol.15
, pp. 300-308
-
-
Mazurek, S.1
Boschek, C.B.2
Hugo, F.3
Eigenbrodt, E.4
-
15
-
-
84856014884
-
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
-
1:CAS:528:DC%2BC3MXhsV2gt7fP
-
Metallo, C.M., Gameiro, P.A., Bell, E.L., Mattaini, K.R., Yang, J., Hiller, K., Jewell, C.M., Johnson, Z.R., Irvine, D.J., Guarente, L., et al. (2012). Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. Nature 481, 380-384.
-
(2012)
Nature
, vol.481
, pp. 380-384
-
-
Metallo, C.M.1
Gameiro, P.A.2
Bell, E.L.3
Mattaini, K.R.4
Yang, J.5
Hiller, K.6
Jewell, C.M.7
Johnson, Z.R.8
Irvine, D.J.9
Guarente, L.10
-
16
-
-
25444512870
-
Identification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesis
-
16027120 10.1074/jbc.M503152200 1:CAS:528:DC%2BD2MXpvVyqtb8%3D
-
Mizuarai, S., Miki, S., Araki, H., Takahashi, K., and Kotani, H. (2005). Identification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesis. J. Biol. Chem. 280, 32434-32441.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32434-32441
-
-
Mizuarai, S.1
Miki, S.2
Araki, H.3
Takahashi, K.4
Kotani, H.5
-
17
-
-
59049087460
-
Bidirectional transport of amino acids regulates mTOR and autophagy
-
19203585 10.1016/j.cell.2008.11.044 1:CAS:528:DC%2BD1MXltFSnsrc%3D
-
Nicklin, P., Bergman, P., Zhang, B., Triantafellow, E., Wang, H., Nyfeler, B., Yang, H., Hild, M., Kung, C., Wilson, C., et al. (2009). Bidirectional transport of amino acids regulates mTOR and autophagy. Cell 136, 521-534.
-
(2009)
Cell
, vol.136
, pp. 521-534
-
-
Nicklin, P.1
Bergman, P.2
Zhang, B.3
Triantafellow, E.4
Wang, H.5
Nyfeler, B.6
Yang, H.7
Hild, M.8
Kung, C.9
Wilson, C.10
-
18
-
-
84866601479
-
Regulation of metabolism by hypoxia-inducible factor 1
-
21785006 10.1101/sqb.2011.76.010678 1:CAS:528:DC%2BC38Xht1ChsbfO
-
Semenza, G.L. (2011). Regulation of metabolism by hypoxia-inducible factor 1. Cold Spring Harb. Symp. Quant. Biol. 76, 347-353.
-
(2011)
Cold Spring Harb. Symp. Quant. Biol.
, vol.76
, pp. 347-353
-
-
Semenza, G.L.1
-
19
-
-
60149091657
-
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
-
19212411 10.1038/nature07762 1:CAS:528:DC%2BD1MXhslCnt70%3D
-
Sreekumar, A., Poisson, L.M., Rajendiran, T.M., Khan, A.P., Cao, Q., Yu, J., Laxman, B., Mehra, R., Lonigro, R.J., Li, Y., et al. (2009). Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature 457, 910-914.
-
(2009)
Nature
, vol.457
, pp. 910-914
-
-
Sreekumar, A.1
Poisson, L.M.2
Rajendiran, T.M.3
Khan, A.P.4
Cao, Q.5
Yu, J.6
Laxman, B.7
Mehra, R.8
Lonigro, R.J.9
Li, Y.10
-
20
-
-
84858604270
-
Metabolic reprogramming: A cancer hallmark even warburg did not anticipate
-
22439925 10.1016/j.ccr.2012.02.014 1:CAS:528:DC%2BC38Xkt1ylsbc%3D
-
Ward, P.S., and Thompson, C.B. (2012). Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 21, 297-308.
-
(2012)
Cancer Cell
, vol.21
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
21
-
-
78650181190
-
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
-
21106670 10.1101/gad.1985910 1:CAS:528:DC%2BC3MXltVKn
-
Wellen, K.E., Lu, C., Mancuso, A., Lemons, J.M., Ryczko, M., Dennis, J.W., Rabinowitz, J.D., Coller, H.A., and Thompson, C. B. (2010). The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. Genes Dev. 24, 2784-2799.
-
(2010)
Genes Dev.
, vol.24
, pp. 2784-2799
-
-
Wellen, K.E.1
Lu, C.2
Mancuso, A.3
Lemons, J.M.4
Ryczko, M.5
Dennis, J.W.6
Rabinowitz, J.D.7
Coller, H.A.8
Thompson, C.B.9
-
22
-
-
77955281020
-
Glutamine addiction: A new therapeutic target in cancer
-
20570523 10.1016/j.tibs.2010.05.003 1:CAS:528:DC%2BC3cXpvFKqs7s%3D
-
Wise, D.R., and Thompson, C.B. (2010). Glutamine addiction: a new therapeutic target in cancer. Trends Biochem. Sci. 35, 427-433.
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 427-433
-
-
Wise, D.R.1
Thompson, C.B.2
-
23
-
-
57749088701
-
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
-
19033189 10.1073/pnas.0810199105 1:CAS:528:DC%2BD1cXhsV2rtL%2FK
-
Wise, D.R., DeBerardinis, R.J., Mancuso, A., Sayed, N., Zhang, X.Y., Pfeiffer, H.K., Nissim, I., Daikhin, E., Yudkoff, M., McMahon, S.B., et al. (2008). Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proc. Natl. Acad. Sci. USA 105, 18782-18787.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18782-18787
-
-
Wise, D.R.1
Deberardinis, R.J.2
Mancuso, A.3
Sayed, N.4
Zhang, X.Y.5
Pfeiffer, H.K.6
Nissim, I.7
Daikhin, E.8
Yudkoff, M.9
McMahon, S.B.10
-
24
-
-
82555170271
-
Nuclear PKM2 regulates betacatenin transactivation upon EGFR activation
-
22056988 10.1038/nature10598 1:CAS:528:DC%2BC3MXhsVagtbvP
-
Yang, W., Xia, Y., Ji, H., Zheng, Y., Liang, J., Huang, W., Gao, X., Aldape, K., and Lu, Z. (2011). Nuclear PKM2 regulates betacatenin transactivation upon EGFR activation. Nature 480, 118-122.
-
(2011)
Nature
, vol.480
, pp. 118-122
-
-
Yang, W.1
Xia, Y.2
Ji, H.3
Zheng, Y.4
Liang, J.5
Huang, W.6
Gao, X.7
Aldape, K.8
Lu, Z.9
-
25
-
-
84856087055
-
Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis
-
22225612 10.1016/j.cell.2011.11.050 1:CAS:528:DC%2BC38XhtFKgsbw%3D
-
Zhang, W.C., Shyh-Chang, N., Yang, H., Rai, A., Umashankar, S., Ma, S., Soh, B.S., Sun, L.L., Tai, B.C., Nga, M.E., et al. (2012). Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis. Cell 148, 259-272.
-
(2012)
Cell
, vol.148
, pp. 259-272
-
-
Zhang, W.C.1
Shyh-Chang, N.2
Yang, H.3
Rai, A.4
Umashankar, S.5
Ma, S.6
Soh, B.S.7
Sun, L.L.8
Tai, B.C.9
Nga, M.E.10
|