A phe-rich region in short-wavelength sensitive opsins is responsible for their aggregation in the absence of 11-cis-retinal

FEBS Letters

Volumn 587, Issue 15, 2013, Pages 2430-2434

  Zhang, Tao ^a   Fu, Yingbin ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

Cone degeneration; G protein coupled receptors (GPCRs); Leber congenital amaurosis (LCA); Medium long wavelength sensitive opsins (M LWS); Opsin aggregation; RPE65 LRAT; Short wavelength sensitive opsins (SWS)

Indexed keywords

GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; LONG WAVELENGTH SENSITIVE OPSIN; MEDIUM WAVELENGTH SENSITIVE OPSIN; OPSIN; PHENYLALANINE; SHORT WAVELENGTH SENSITIVE OPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LEBER CONGENITAL AMAUROSIS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RETINA CONE;

CONE DEGENERATION; G-PROTEIN-COUPLED RECEPTORS (GPCRS); LEBER CONGENITAL AMAUROSIS (LCA); LRAT; MEDIUM/LONG-WAVELENGTH SENSITIVE OPSINS (M/LWS); OPSIN AGGREGATION; RPE65; SHORT-WAVELENGTH SENSITIVE OPSINS (SWS);

AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; OPSINS; PHENYLALANINE; RETINALDEHYDE; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA;

EID: 84880700248     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.06.012     Document Type: Article

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