Body mass index, lifestyles, physical performance and cognitive decline: The "treviso Longeva (Trelong)" study

Journal of Nutrition, Health and Aging

Volumn 17, Issue 4, 2013, Pages 378-384

  Gallucci, Maurizio ^a,h   Mazzuco, S ^b   Ongaro, F ^b   Di Giorgi, E ^c   Mecocci, P ^d   Cesari, M ^e   Albani, D ^f   Forloni, G L ^f   Durante, E ^g   Gajo, G B ^g   Zanardo, A ^g,h   Siculi, M ^g   Caberlotto, L ^g   Regini, C ^h  

^a General Hospital of Treviso   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c Territorial Health Services of Treviso   (Italy)

^d SANTA MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

^e UNIVERSITÉ DE TOULOUSE   (France)

^f MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^g General Hospital of Treviso   (Italy)

^h Interdisciplinary Geriatric Research Foundation   (Italy)

Author keywords

body mass index (BMI); Cognitive decline; lifestyles; physical performance

Indexed keywords

AGED; ARTICLE; BODY MASS; CHARLSON COMORBIDITY INDEX; COGNITIVE DEFECT; COMORBIDITY; DEPRESSION; EDUCATIONAL STATUS; FEMALE; FOLLOW UP; HAND GRIP; HEARING ACUITY; HUMAN; ITALY; LIFESTYLE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MEDITERRANEAN DIET; MINI MENTAL STATE EXAMINATION; PHYSICAL PERFORMANCE; PRIORITY JOURNAL; READING; SCORING SYSTEM; SHORT PHYSICAL PERFORMANCE BATTERY SCORE; SOCIAL BEHAVIOR; SURVIVOR; VISUAL ACUITY;

EID: 84880699136     PISSN: 12797707     EISSN: 17604788     Source Type: Journal    
DOI: 10.1007/s12603-012-0397-1     Document Type: Article

References (103)

1. Ferri CP, Prince M, Brayne C, Brodaty H et al.; Global prevalence of dementia: a Delphi consensus study. Lancet 2005 dec 17;366(9503):2112-2117
2. World Health Organization. World Health Report 2003 - Shaping the future. Geneva: WHO, 2003.
3. Gustafson DR, Rothenberg E, Blennow K, Steen B, Skoog I. An 18-year follow up of overweight and risk for Alzheimer's disease. Arch Intern Med 2003;163:1524-1528.
4. Kivipelto M, Ngandu T, Fratiglioni L, et al. Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol 2005;62:1556-1560.
5. Rosengren A, Skoog I, Gustafson D, Wilhelmsen L. Body mass index, other cardiovascular risk factors, and hospitalization for dementia. Arch Intern Med 2005;165:321-326.
6. Whitmer RA, Gunderson EP, Barrett-Connor E, Quesenberry CP, Jr.; Yaffe K. Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ 2005;330:1360-1364.
7. Luchsinger JA, Patel B, Tang MX, Schupf N, Mayeux R. Measures of adiposity and dementia risk in elderly persons. Arch Neurol 2007;64:392-398.
8. Stewart R, Masaki K, Xue QL, et al. A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study. Arch Neurol 2005;62:55-60.
9. Atti AR, Palmer K, Volpato S, Winblad B, De Ronchi D, Fratiglioni L. Late-life body mass index and dementia incidence: nine-year follow-up data from the Kungsholmen Project. J Am Geriatr Soc 2008;56:111-116.
10. Barrett-Connor E, Edelstein SL, Corey-Bloom J, Wiederholt WC. Weight loss precedes dementia in community-dwelling older adults. J Am Geriatr Soc 1996;44:1147-1152.
11. Buchman AS, Wilson RS, Bienias JL, Shah RC, Evans DA, Bennett DA. Change in body mass index and risk of incident Alzheimer disease. Neurology 2005;65:892-897.
12. Fitzpatrick AL, Kuller LH, Lopez OL, et al. Midlife and late-life obesity and the risk of dementia: cardiovascular health study. Arch Neurol 2009;66:336-342.
13. Alfaro-Acha A, Al Snih S, Raji MA, Kuo YF, Markides KS, Ottenbacher KJ. Handgrip strength and cognitive decline in older Mexi-can Americans. J Gerontol A Biol Sci Med Sci. 2006;61(8):859-865.
14. Alfaro-Acha A, Al Snih S, Raji MA, Markides KS, Ottenbacher KJ. Does 8-foot walk time predict cognitive decline in older Mexicans Americans? J Am Geriatr Soc. 2007;55(2):245-251.
15. Inzitari M, Newman AB, Yaffe K, et al. Gait speed predicts decline in attention and psychomotor speed in older Adults: The Health Aging and Body Composition Study. Neuroepidemiology. 2007;29(3-4):156-162.
16. Wang L, Larson EB, Bowen JD, van Belle G. Performance-based physical function and future dementia in older people. Arch Intern Med. 2006;166(10):1115-1120.
17. Marsili M, Marsiglia D: Tavole di mortalità della popolazione italiana per provincia e regione di residenza. Anno 1998, Roma, Servizio Popolazione Istruzione e Cultura, 2001
18. Gallucci M, Ongaro F, Bresolin F, et al. The Treviso Longeva (Trelong) study: a biomedical, demographic, economic and social investigation on people 70 years and over in a typical town of North-East of Italy. Arch Gerontol Geriatr 2007;44Suppl 1:173-192.
19. Folstein MF, Folstein SE, McHugh PR: "Mini-Mental State" A practical method for grading the cognitive state of patients for the clinician. J Psychiatric Res 1975; 12:189-198
20. Magni E, Binetti G, Bianchetti A, et al: Mini-mental state examination: a normative study in Italian elderly population. Eur J Neurol 1996; 3:1-5
21. Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA, Wallace RB, 1994. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J. Gerontol. Biol. Sci. Med. Sci. 49, M85-M94.
22. Gallucci M, Ongaro F, Meggiolaro S et al.; Factors related to disability: Evidence from the "Treviso Longeva (TRELONG) Study", Archives of Gerontology and Geriatrics 52 (2011) 309-316
23. Charlson, M.E.; Pompei, P.; Ales, K.L.; McKenzie, C.R.; 1987. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J. Chron. Dis. 40, 373-383.
24. Cleves, M.A.; Sanchez, N.; Draheim, M.; 1997. Evaluation of two competing methods for calculating Charlson's comorbidity index when analyzing short-term mortality using administrative data. J. Clin. Epidemiol. 50, 903-908.
25. Singh, B.; Bhaya, M.; Stern, J.; Roland, J.T.; Zimbler, M.; Rosenfeld, R.M.; Har-El, G.; Lucente, F.E.; 1997. Validation of the Charlson comorbidity index in patients with head and neck cancer: a multi-institutional study. Laryngoscope 107, 1469-1475.
26. Zhang, J.X.; Iwashyna, T.J.; Christakis, N.A.; 1999. The performance of different lookback periods and sources of information for Charlson comorbidity adjustment in Medicare claims. Med. Care 37, 1128-1139.
27. Schneeweiss, S.; Maclure, M.; 2000. Use of comorbidity scores for control of confounding in studies using administrative databases. Int. J. Epidemiol. 29, 891-898.
28. Yesavage, J.A.; Brink, T.L.; Rose, T.L.; Lum, O.; Huang, V.; Adey, M.; Leirer, V.O.; 1983. Development and validation of a geriatric depression screening scale: a preliminary report. J. Psychiatr. Res. 17, 37-49.
29. Montorio, I.; Izal, M.; 1996. The Geriatric Depression Scale: a review of its development and utility. Int. Psychogeriatr. 8, 103-112.
30. Gallucci, M.; Antuono, P.; Ongaro, F.; Forloni, P.L.; Albani, D.; Amici, G.P.; Regini, C.; 2009. Physical activity, socialization and reading in the elderly over the age of seventy: What is the relation with cognitive decline? Evidence from "The Treviso Longeva (TRELONG) study" Arch. Gerontol. Geriatr. 48, 284-286.
31. Rees, S.; Harborne, J.; 1984. Flavonoids and other phenolics of Cichorium and related members of the Lactueaceae (Compositae). Bot. J. Linn. Soc. 89, 313-319.
32. Papetti, A.; Daglia, M.; Gazzani, G.; 2002. Anti- and pro-oxidant activity of watersoluble compounds in Cichorium intybus var. Silvestre (Treviso red chicory). J. Pharmaceut. Biomed. Anal. 30, 939-945.
33. Buckland, G.; Bach, A.; Serra-Majem, L.; 2008. Obesity and the Mediterranean diet: a systematic review of observational and intervention studies. Obes. Rev. 9, 582-593.
34. R Development Core Team (2012). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07- 0, URL http://www.R-project.org/.
35. Hedden T, Gabrieli JD: Insights into the ageing mind: a view from cognitive neuroscience. Nat Rev Neurosci 2004, 5:87-96.
36. Salthouse TA: Memory aging from 18 to 80. Alzheimer Dis Assoc Disord 2003, 17:162-167.
37. Yakhno NN, Zakharov VV, Lokshina AB: Impairment of memory and attention in the elderly. Neurosci Behav Physiol 2007, 37:203-208.
38. Royall DR, Palmer R, Chiodo LK, Polk MJ: Declining executive control in normal aging predicts change in functional status: The Freedom House Study. J Am Geriatr Soc 2004, 52:346-352.
39. Coppin AK, Shumway-Cook A, Saczynski JS, Patel KV, Ble A, Ferrucci L, Guralnik JM: Association of executive function and performance of dualtask physical tests among older adults: analyses from the InChianti study. Age Ageing 2006, 35:619-624.
40. Salthouse TA: The processing-speed theory of adult age differences in cognition. Psychol Rev 1996, 103:403-428.
41. Cahn-Weiner DA, Malloy PF, Boyle PA, Marran M, Salloway S: Prediction of functional status from neuropsychological tests in community-dwelling elderly individuals. Clin Neuropsychol 2000, 14:187-195.
42. Lee Y, Kim JH, Lee KJ, Han G, Kim JL: Association of cognitive status with functional limitation and disability in older adults. Aging Clin Exp Res 2005, 17:20-28.
43. Owsley C, McGwin G Jr: Association between visual attention and mobility in older adults. J Am Geriatr Soc 2004, 52:1901-1906.
44. Katz MJ, Lipton RB, Hall CB, Zimmerman ME, Sanders AE, Verghese J, Dickson DW, Derby CA. Age-specific and Sex-specific Prevalence and Incidence of Mild Cognitive Impairment, Dementia, and Alzheimer Dementia in Blacks and Whites: A Report From the Einstein Aging Study. Alzheimer Dis Assoc Disord. 2011 Dec 7.
45. Whitmer, R.A.; Gunderson, E.P.; Quesenberry Jr.; C.P.; Zhou, J.; Yaffe, K.; 2007. Body mass index in midlife and risk of Alzheimer disease and vascular dementia. Curr. Alzheimer Res. 4, 103-109.
46. Hayden, K.; Zandi, P.; Lyketsos, C.; Khachaturian, A.; Bastian, L.; Charoonruk, G.; Tschanz, J.; Norton, M.; Pieper, C.; Munger, R.; Breitner, J.; Welsh-Bohmer, K.; Cache County Investigators, 2006. Vascular risk factors for incident Alzheimer disease and vascular dementia: the Cache County study. Alzheimer Dis. Assoc. Disord. 20, 93-100.
47. Nourhashemi F, Deschamps V, Larrieu S, Letenneur L, Dartigues JF, Barberger-Gateau P. Body mass index and incidence of dementia: the PAQUID study. Neurology 2003;60:117-119.
48. Chiang, C.J.; Yip, P.K.; Wu, S.C.; Lu, C.S.; Liou, C.W.; Liu, H.C.; Liu, C.K.; Chu, C.H.; Hwang, C.S.; Sung, S.F.; Hsu, Y.D.; Chen, C.C.; Liu, S.I.; Yan, S.H.; Fong, C.S.; Chang, S.F.; You, S.L.; Chen, C.J.; 2007. Midlife risk factors for subtypes of dementia: a nested case-control study in Taiwan. Am. J. Geriatr. Psychiatry 15, 762-771.
49. Luchsinger, J.A.; Patel, B.; Tang, M.X.; Schupf, N.; Mayeux, R.; 2007. Measures of adiposity and dementia risk in elderly persons. Arch. Neurol. 64, 392-398.
50. Buchman, A.S.; Wilson, R.S.; Bienias, J.L.; Shah, R.C.; Evans, D.A.; Bennett, D.A.; 2005. Change in body mass index and risk of incident Alzheimer disease. Neurology 65, 892-897.
51. Faxen-Irving, G.; Basun, H.; Cederholm, T.; 2005. Nutritional and cognitive relationships and longterm mortality in patients with various dementia disorders. Age Ageing 34, 136-141.
52. Hogan, D.B.; Ebly, E.M.; Rockwood, K.; 1997. Weight, blood pressure, osmolarity, and glucose levels across various stages of Alzheimer's disease and vascular dementia. Dement. Geriatr. Cogn. Disord. 8, 147-151.
53. Knopman, D.S.; Edland, S.D.; Cha, R.H.; Petersen, R.C.; Rocca, W.A.; 2007. Incident dementia in women is preceded by weight loss by at least a decade. Neurology 69, 739-746.
54. White, H.; Pieper, C.; Schmader, K.; Fillenbaum, G.; 1996. Weight change in Alzheimer's disease. J. Am. Geriatr. Soc. 44, 265-272.
55. White, H.; Pieper, C.; Schmader, K.; 1998. The association of weight change in Alzheimer's disease with severity of disease and mortality: a longitudinal analysis. J. Am. Geriatr. Soc. 46, 1223-1227.
56. Dey DK, Rothenberg E, Sundh V, et al: Height and body weight in the elderly. I. A 25- year longitudinal study of a population aged 70 to 95 years. Eur J Clin Nutr 1999; 53:905-914
57. Flicker L, McCaul KA, Hankey GJ, et al: Body mass index and survival in men and women aged 70 to 75. J Am Geriatr Soc 2010; 58:234-241
58. Gustafson, D.; Mazzuco, S.; Gallucci, M.; et al.: Body mass index, cognition, disability, APOE genotype and mortality: the "TREVISO LONGEVA (TRELONG)" Study. Am J Geriatr Psychiatry, 2011 Oct 8
59. Gustafson, D.: A life course of adiposity and dementia. Eur J Pharmacol 2008; 585:163-175
60. Ross, M.G.; Desai, M.; Khorram, O.; McKnight, R.A.; Lane, R.H.; Torday, J.; 2007. Gestational programming of offspring obesity: a potential contributor to Alzheimer's disease. Curr. Alzheimer Res. 4, 213-217.
61. Kalmijn S, Foley D, White L, et al. Metabolic cardiovascular syndrome and risk of dementia in Japanese-American elderly men: the Honolulu-Asia aging study. Arterioscler Thromb Vasc Biol. 2000;20:2255-2260.
62. deLeon, M.J.; George, A.E.; Golomb, J.; Tarshish, C.; Convit, A.; Kluger, A.; Santi, S.; McRae, T.; Ferris, S.H.; Reisberg, B.; Ince, C.; Rusinek, H.; Bobinski, M.; Quinn, B.; Miller, D.C.; Wisniewski, H.M.; 1996. Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease. Neurobiol. Aging 18, 1-11.
63. Visser, P.J.; Verhey, F.R.J.; Hofman, P.A.M.; Scheltens, P.; Jolles, J.; 2002. Medial temporal lobe atrophy predicts Alzheimer' disease in patients with minor cognitive impairment. J. Neurol. Neurosur. Psychiatr. 72, 491-497.
64. Gustafson, D.; Lissner, L.; Bengtsson, C.; Björkelund, C.; Skoog, I.; 2004. A 24-year follow-up of body mass index and cerebral atrophy. Neurology 63, 1876-1881.
65. Ward, M.A.; Carlsson, C.M.; Trivedi, M.A.; Sager, M.A.; Johnson, S.C.; 2005. The effect of body mass index on global brain volume in middle-aged adults: a cross sectional study. BMC Neurol. 5, 23-29.
66. Wolf-Klein GP, Silverstone FA. Weight loss in Alzheimer's disease: an international review of the literature. Int Psychogeriatr 1994;6:135-142.
67. Wang GJ, Volkow ND, Logan J, et al. Brain dopamine and obesity. Lancet 2001;357:354-357.
68. Shatenstein B, Kergoat MJ, Nadon S. Weight change, nutritional risk and its determinants among cognitively intact and demented elderly Canadians. Can J Public Health 2001;92:143-149.
69. Payette H, Kergoat MJ, Shatenstein B, Boutier V, Nadon S. Validity of self-reported height and weight estimates in cognitively-intact and impaired elderly individuals. J Nutr Health Aging 2000;4:223-228.
70. Cronin-Stubbs D, Beckett LA, Scherr PA, et al. Weight loss in people with Alzheimer's disease: a prospective population based analysis. Br Med J 1997;314:178-179.
71. White H, Pieper C, Schmader K, Fillenbaum G. A longitudinal analysis of weight change in Alzheimer's disease. J Am Geriatr Soc 1997;45:531-532.
72. Salvà A, Andrieu S, Fernandez E, Schiffrin EJ, Moulin J, Decarli B, Rojano-i-Luque X, Guigoz Y, Vellas B; NutriAlz group. Health and nutrition promotion program for patients with dementia (NutriAlz): cluster randomized trial. J Nutr Health Aging. 2011;15(10):822-830.
73. Gillette Guyonnet S, Abellan Van Kan G, Alix E, Andrieu S, Belmin J, Berrut G, Bonnefoy M, Brocker P, Constans T, Ferry M, Ghisolfi-Marque A, Girard L, Gonthier R, Guerin O, Hervy MP, Jouanny P, Laurain MC, Lechowski L, Nourhashemi F, Raynaud-Simon A, Ritz P, Roche J, Rolland Y, Salva T, Vellas B; International Academy on Nutrition and Aging Expert Group. IANA (International Academy on Nutrition and Aging) Expert Group: weight loss and Alzheimer's disease. J Nutr Health Aging. 2007 Jan-Feb;11(1):38-48.
74. Andrieu S, Reynish W, Nourhashemi F et al. Nutritional risk factors for institutional placement in Alzheimer's disease after one year follow-up. J Nutr Health Aging 2001; 5: 113-117
75. Inelmen EM, Sergi G, Coin A, Girardi A and Manzato E. An open-ended question: Alzheimer's disease and involuntary weight loss: which comes first? Aging Clin Exp Res, 2010, Vol. 22, No 3, 192-197.
76. Uchida S, Kawashima R: Reading and solving arithmetic problems improves cognitive functions of normal aged people: a randomized controlled study. Age (Dordr) 2008, 30:21-29.
77. Nouchi R, Taki Y, Takeuchi H, et al. Beneficial effects of reading aloud and solvingsimple arithmetic calculations (learning therapy) on a wide range of cognitive functions in the healthy elderly: study protocol for a randomized controlled trial. Trials 2012, 13:32
78. Jefferson AL, Gibbons LE, Rentz DM, Carvalho JO, Manly J, Bennett DA and Jones R N (2011), A Life Course Model of Cognitive Activities, Socioeconomic Status, Education, Reading Ability, and Cognition. Journal of the American Geriatrics Society, 59: 1403-1411.
79. Lindenberger U, Baltes P. Sensory functioning and intelligence in old age: a strong connection. Psychol Aging 1994;9:339-355.
80. Christensen H, Mackinnon AJ, Korten A, Jorm AF. The "Common Cause Hypothesis" of cognitive aging: evidence for not only a common factor but also specific associations of age with vision and grip strength in a cross-sectional analysis. Psychol Aging 2001;16:588-599.
81. Anstey KJ, Smith GA. Interrelationships among biological markers of aging, health, activity, acculturation and cognitive performance in late adulthood. Psychol Aging 1999;14:605-618.
82. Guralnik JM, Ferrucci L, Penninx BWJH, Kasper JD, Leveille SG, Bandeen-Roche K, Fried LP. New and worsening conditions and change in physical and cognitive peformance during weekly evaluations over 6 months: The Women's Health and Aging Study. J Gerontol 1999;54A:M410-M422.
83. Kuh D, Bassey EJ, Butterworth S, Hardy R, Wadsworth MEJ. on behalf of the Musculoskeletal study team. Grip strength, postural control, and functional leg power in a representative cohort of British men and women; associations with physical activity, health status, and socioeconomic conditions. J Gerontol Med Sci 2005;60A:224-231.
84. Richards M. Cognitive links across the lifecourse and implications for health in later life. Age Ageing 2003;29:477-478.
85. Richards M, Sacker A. Lifetime antecedents of cognitive reserve. J Clin Exp Neuropsychol 2003;25:614-624.
86. Atkinson HH, Rapp SR, Williamson JD, Lovato J, Absher JR, Gass M, Henderson VW, Johnson KC, Kostis JB, Sink KM, Mouton CP, Ockene JK, Stefanick ML, Lane DS, Espeland MA. The relationship between cognitive function and physical performance in older women: results from the women's health initiative memory study. J Gerontol A Biol Sci Med Sci. 2010 Mar;65(3):300-306. Epub 2009 Sep 29.
87. Angevaren M, Aufdemkampe G, Verhaar HJ, Aleman A, Vanhees L. Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment. Cochrane Database Syst Rev. 2008 Jul 16;(3):CD005381.
88. Teri L, Logsdon RG, McCurry SM. Exercise interventions for dementia and cognitive impairment: the Seattle Protocols. J Nutr Health Aging. 2008 Jun-Jul;12(6):391-394.
89. Geda YE, Roberts RO, Knopman DS et al.; Physical exercise, aging, and mild cognitive impairment: a population-based study. Arch Neurol. 2010 Jan;67(1):80-86.
90. Liu-Ambrose T, Eng JJ, Boyd LA, Jacova C, Davis JC, Bryan S, Lee P, Brasher P, Hsiung GY. Promotion of the mind through exercise (PROMoTE): a proof-of-concept randomized controlled trial of aerobic exercise training in older adults with vascular cognitive impairment. BMC Neurol. 2010 Feb 17;10:14.
91. Schneider BC, Lichtenberg PA. Executive ability and physical performance in urban Black older adults. Archives of Clinical Neuropsychology 23 (2008) 593-601
92. Verghese J, Wang C, Lipton RB, Holtzer R, Xue X. Quantitative gait dysfunction and risk of cognitive decline and dementia. J Neurol Neu.rosurg Psychiatry. 2007;78(9):929-935.
93. Buchman AS, Wilson RS, Boyle PA, Bienias JL, Bennett DA. Grip strength and the risk of incident Alzheimer's disease. Neuroepidemiol.ogy. 2007;29(1-2):66-73.
94. Verghese J, Lipton RB, Hall CB, Kuslansky G, Katz MJ, Buschke H. Abnormality of gait as a predictor of non-Alzheimer's dementia. N Engl J Med. 200228;347(22):1761-1768.
95. Marquis S, Moore MM, Howieson DB, et al. Independent predictors of cognitive decline in healthy elderly persons. Arch Neurol. 2002;59(4):601-606.
96. Louis ED, Tang MX, Mayeux R. Parkinsonian signs in older people in a community-based study: risk of incident dementia. Arch Neurol. 2004;61(8):1273-1276.
97. Waite LM, Grayson DA, Piguet O, Creasey H, Bennett HP, Broe GA. Gait slowing as a predictor of incident dementia: 6-year longitudinal data from the Sydney Older Persons Study. J Neurol Sci. 2005;229-230:89
98. Abellan van Kan G, Rolland Y, Andrieu S, Bauer J, Beauchet O, Bonnefoy M, Cesari M, Donini LM, Gillette Guyonnet S, Inzitari M, Nourhashemi F, Onder G, Ritz P, Salva A, Visser M, Vellas B. Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force. J Nutr Health Aging. 2009 Dec;13(10):881-889.
99. Guralnik, J M, Ferrucci, L, Simonsick, E M, Salive, M E, & Wallace, R B (1995). Lowerextremity function in persons over the age of 70 years as a predictor of subsequent disability. The New England Journal of Medicine, 332(9), 556-561.
100. Ferrer E.; Salthouse T.A.; Stewart W.F.; Schwartz B.S. (2004) Modeling age and retest processes in longitudinal studies of cognitive abilities. Psychology and Aging, 19(2), 243-259.
101. Mazzonna F. and Peracchi F. (2009) Aging, cognitive abilities and retirement in Europe. CEIS Tor Vergata Research Paper Series, vol. 7, Issue 5, n. 152.
102. Cheng G, Huang C, Deng H, Wang H. Diabetes as a risk factor for dementia and mild cognitive impairment: a meta-analysis of longitudinal studies. Intern Med J. 2012 May;42(5):484-491.
103. Sharp SI, Aarsland D, Day S, Sonnesyn H, Ballard C. Hypertension is a potential risk factor for vascular dementia: systematic review. Int J Geriatr Psychiatry. 2011;26:661-669