Cytoplasmic localization of DGKζ exerts a protective effect against p53-mediated cytotoxicity

Journal of Cell Science

Volumn 126, Issue 13, 2013, Pages 2785-2797

  Tanaka, Toshiaki ^a   Okada, Masashi ^a   Hozumi, Yasukazu ^a   Tachibana, Ken ^a   Kitanaka, Chifumi ^a   Hamamoto, Yoshioki ^a   Martelli, Alberto M ^b   Topham, Matthew K ^c   Iino, Mitsuyoshi ^a   Goto, Kaoru ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

DGK ; Doxorubicin; Excitotoxicity; Nucleocytoplasmic translocation; p53; Ubiquitin proteasome system

Indexed keywords

DIACYLGLYCEROL; DIACYLGLYCEROL KINASE; DIACYLGLYCEROL KINASE ZETA; DOXORUBICIN; KAINIC ACID; NUCLEOSOME ASSEMBLY PROTEIN 1; PROTEASOME; PROTEIN P53; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; CYTOPLASM; CYTOTOXICITY; DELETION MUTANT; DNA BINDING; DNA DAMAGE; ENZYME ACTIVE SITE; EXCITOTOXICITY; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SECOND MESSENGER; SEIZURE; TRANSACTIVATION;

DGKΖ; DOXORUBICIN; EXCITOTOXICITY; NUCLEOCYTOPLASMIC TRANSLOCATION; P53; UBIQUITIN-PROTEASOME SYSTEM;

ANIMALS; BINDING SITES; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; CYTOPLASM; DIACYLGLYCEROL KINASE; DIGLYCERIDES; DNA DAMAGE; DOXORUBICIN; GENE EXPRESSION REGULATION; HUMANS; INJECTIONS, INTRAPERITONEAL; KAINIC ACID; MALE; MICE; MICE, INBRED C57BL; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN;

EID: 84880689056     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.118711     Document Type: Article

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